HK1256304A1 - 用於生成單克隆抗體的方法和試劑 - Google Patents
用於生成單克隆抗體的方法和試劑Info
- Publication number
- HK1256304A1 HK1256304A1 HK18115369.1A HK18115369A HK1256304A1 HK 1256304 A1 HK1256304 A1 HK 1256304A1 HK 18115369 A HK18115369 A HK 18115369A HK 1256304 A1 HK1256304 A1 HK 1256304A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- reagents
- methods
- monoclonal antibodies
- creating monoclonal
- creating
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
- C07K16/081—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from DNA viruses
- C07K16/082—Hepadnaviridae, e.g. hepatitis B virus
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/44—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material not provided for elsewhere, e.g. haptens, metals, DNA, RNA, amino acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201161450922P | 2011-03-09 | 2011-03-09 | |
US201161560006P | 2011-11-15 | 2011-11-15 | |
US201161566876P | 2011-12-05 | 2011-12-05 | |
US201261594729P | 2012-02-03 | 2012-02-03 |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1256304A1 true HK1256304A1 (zh) | 2019-09-20 |
Family
ID=45922811
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK18115369.1A HK1256304A1 (zh) | 2011-03-09 | 2018-11-30 | 用於生成單克隆抗體的方法和試劑 |
Country Status (12)
Country | Link |
---|---|
US (2) | US9920110B2 (zh) |
EP (2) | EP2683736B1 (zh) |
JP (3) | JP6211931B2 (zh) |
KR (3) | KR20190107761A (zh) |
CN (2) | CN108220297A (zh) |
AU (3) | AU2012225310B2 (zh) |
CA (1) | CA2829606C (zh) |
DK (1) | DK2683736T3 (zh) |
ES (1) | ES2666301T3 (zh) |
HK (1) | HK1256304A1 (zh) |
HU (1) | HUE037095T2 (zh) |
WO (1) | WO2012122484A1 (zh) |
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ES2726702T3 (es) | 2009-01-15 | 2019-10-08 | Adaptive Biotechnologies Corp | Perfilado de la inmunidad adaptativa y métodos para la generación de anticuerpos monoclonales |
EP2783214A2 (en) | 2011-11-23 | 2014-10-01 | The Board of Regents of The University of Texas System | Proteomic identification of antibodies |
EP2823060B1 (en) | 2012-03-05 | 2018-02-14 | Adaptive Biotechnologies Corporation | Determining paired immune receptor chains from frequency matched subunits |
SG11201407107VA (en) | 2012-05-08 | 2014-11-27 | Adaptive Biotechnologies Corp | Compositions and method for measuring and calibrating amplification bias in multiplexed pcr reactions |
CA2875695C (en) | 2012-06-15 | 2022-11-15 | The Board Of Regents Of The University Of Texas System | High throughput sequencing of multiple transcripts of a single cell |
SG10201707394PA (en) * | 2013-03-15 | 2017-10-30 | Adaptive Biotechnologies Corp | Uniquely tagged rearranged adaptive immune receptor genes in a complex gene set |
US9708657B2 (en) | 2013-07-01 | 2017-07-18 | Adaptive Biotechnologies Corp. | Method for generating clonotype profiles using sequence tags |
US10208125B2 (en) | 2013-07-15 | 2019-02-19 | University of Pittsburgh—of the Commonwealth System of Higher Education | Anti-mucin 1 binding agents and uses thereof |
CA2922372C (en) * | 2013-09-09 | 2018-05-15 | Shimadzu Corporation | Method for preparing peptide fragments, kit for preparing peptide fragments to be used therein, and analysis method |
GB201316644D0 (en) * | 2013-09-19 | 2013-11-06 | Kymab Ltd | Expression vector production & High-Throughput cell screening |
US10066265B2 (en) | 2014-04-01 | 2018-09-04 | Adaptive Biotechnologies Corp. | Determining antigen-specific t-cells |
ES2777529T3 (es) | 2014-04-17 | 2020-08-05 | Adaptive Biotechnologies Corp | Cuantificación de genomas de células inmunitarias adaptativas en una mezcla compleja de células |
EP3161166A4 (en) * | 2014-06-25 | 2017-11-29 | The Rockefeller University | Compositions and methods for rapid production of versatile nanobody repertoires |
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US10246701B2 (en) | 2014-11-14 | 2019-04-02 | Adaptive Biotechnologies Corp. | Multiplexed digital quantitation of rearranged lymphoid receptors in a complex mixture |
CN104560979B (zh) * | 2015-01-20 | 2017-04-05 | 中国人民解放军第三军医大学 | 基于高通量测序构建鼠bcr重链文库的多重pcr引物和方法 |
CN104560980B (zh) * | 2015-01-20 | 2017-04-05 | 中国人民解放军第三军医大学 | 基于高通量测序构建鼠BCR轻链Lamda文库的多重PCR引物和方法 |
AU2016222788B2 (en) | 2015-02-24 | 2022-03-31 | Adaptive Biotechnologies Corp. | Methods for diagnosing infectious disease and determining HLA status using immune repertoire sequencing |
CN107635478A (zh) | 2015-03-06 | 2018-01-26 | 英国质谱公司 | 通过质谱或离子迁移谱进行的组织分析 |
US11367605B2 (en) | 2015-03-06 | 2022-06-21 | Micromass Uk Limited | Ambient ionization mass spectrometry imaging platform for direct mapping from bulk tissue |
GB2554206B (en) | 2015-03-06 | 2021-03-24 | Micromass Ltd | Spectrometric analysis of microbes |
EP3264989B1 (en) | 2015-03-06 | 2023-12-20 | Micromass UK Limited | Spectrometric analysis |
WO2016142693A1 (en) | 2015-03-06 | 2016-09-15 | Micromass Uk Limited | In vivo endoscopic tissue identification tool |
CN110057901B (zh) * | 2015-03-06 | 2022-07-01 | 英国质谱公司 | 拭子和活检样品的快速蒸发电离质谱和解吸电喷雾电离质谱分析 |
WO2016142674A1 (en) | 2015-03-06 | 2016-09-15 | Micromass Uk Limited | Cell population analysis |
US10513733B2 (en) | 2015-03-23 | 2019-12-24 | Board Of Regents, The University Of Texas System | High throughout sequencing of paired VH and VL transcripts from B cells secreting antigen-specific antibodies |
WO2016161273A1 (en) | 2015-04-01 | 2016-10-06 | Adaptive Biotechnologies Corp. | Method of identifying human compatible t cell receptors specific for an antigenic target |
WO2017044885A1 (en) * | 2015-09-09 | 2017-03-16 | uBiome, Inc. | Method and system for microbiome-derived diagnostics and therapeutics for conditions associated with cerebro-craniofacial health |
EP3443354A1 (en) | 2016-04-14 | 2019-02-20 | Micromass UK Limited | Spectrometric analysis of plants |
CN106047857B (zh) * | 2016-06-01 | 2020-04-03 | 苏州金唯智生物科技有限公司 | 一种发掘特异性功能抗体的方法 |
CN107525934A (zh) * | 2016-06-21 | 2017-12-29 | 张效龙 | 一种测定血液中抗体氨基酸序列的方法 |
US10428325B1 (en) | 2016-09-21 | 2019-10-01 | Adaptive Biotechnologies Corporation | Identification of antigen-specific B cell receptors |
US11401299B2 (en) * | 2017-07-21 | 2022-08-02 | Novimmune Sa | Generating multispecific antibody mixtures and methods of uses thereof |
CN109425662A (zh) * | 2017-08-23 | 2019-03-05 | 深圳华大基因研究院 | 一种鉴定蛋白的方法及系统 |
WO2019084538A1 (en) | 2017-10-27 | 2019-05-02 | Board Of Regents, The University Of Texas System | TUMOR SPECIFIC ANTIBODIES, T CELL RECEPTORS AND METHODS OF IDENTIFICATION THEREOF |
US11254980B1 (en) | 2017-11-29 | 2022-02-22 | Adaptive Biotechnologies Corporation | Methods of profiling targeted polynucleotides while mitigating sequencing depth requirements |
US11155575B2 (en) | 2018-03-21 | 2021-10-26 | Waters Technologies Corporation | Non-antibody high-affinity-based sample preparation, sorbent, devices and methods |
CN108713136B (zh) * | 2018-03-29 | 2020-10-09 | 深圳达闼科技控股有限公司 | 物质检测方法、装置、电子设备及计算机可读存储介质 |
CN108530533B (zh) * | 2018-04-13 | 2020-09-04 | 吉林大学 | 猪瘟病毒单克隆抗体hk24及医用用途 |
US20220034902A1 (en) * | 2018-12-11 | 2022-02-03 | Merck Sharp & Dohme Corp. | Method for identifying high affinity monoclonal antibody heavy and light chain pairs from high throughput screens of b-cell and hybridoma libraries |
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IT202100019334A1 (it) * | 2021-07-21 | 2023-01-21 | Univ Degli Studi Di Pavia | Metodo per l’identificazione dell’intera sequenza della regione variabile delle catene pesanti e leggere di immunoglobuline |
CN115894687A (zh) * | 2022-03-31 | 2023-04-04 | 台州恩泽医疗中心(集团) | 一种抗hla-g1,-g2,-g5及hla-g6异构体分子的单克隆抗体及其用途 |
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-
2012
- 2012-03-09 KR KR1020197026655A patent/KR20190107761A/ko not_active Application Discontinuation
- 2012-03-09 CN CN201810154961.6A patent/CN108220297A/zh active Pending
- 2012-03-09 KR KR1020197000660A patent/KR20190006083A/ko not_active Application Discontinuation
- 2012-03-09 EP EP12711501.2A patent/EP2683736B1/en active Active
- 2012-03-09 EP EP17196465.3A patent/EP3345922A1/en not_active Withdrawn
- 2012-03-09 US US13/416,582 patent/US9920110B2/en active Active
- 2012-03-09 KR KR1020137026647A patent/KR101938343B1/ko active IP Right Grant
- 2012-03-09 WO PCT/US2012/028501 patent/WO2012122484A1/en unknown
- 2012-03-09 CN CN201280021326.1A patent/CN103842379A/zh active Pending
- 2012-03-09 CA CA2829606A patent/CA2829606C/en active Active
- 2012-03-09 AU AU2012225310A patent/AU2012225310B2/en active Active
- 2012-03-09 JP JP2013557906A patent/JP6211931B2/ja active Active
- 2012-03-09 ES ES12711501.2T patent/ES2666301T3/es active Active
- 2012-03-09 DK DK12711501.2T patent/DK2683736T3/en active
- 2012-03-09 HU HUE12711501A patent/HUE037095T2/hu unknown
-
2017
- 2017-09-13 JP JP2017175320A patent/JP6557709B2/ja not_active Expired - Fee Related
- 2017-10-12 AU AU2017245395A patent/AU2017245395B2/en active Active
-
2018
- 2018-01-19 US US15/875,615 patent/US20190002532A1/en not_active Abandoned
- 2018-11-30 HK HK18115369.1A patent/HK1256304A1/zh unknown
-
2019
- 2019-07-11 JP JP2019128863A patent/JP2019195335A/ja active Pending
- 2019-08-14 AU AU2019216660A patent/AU2019216660A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
KR20140010436A (ko) | 2014-01-24 |
JP6211931B2 (ja) | 2017-10-11 |
KR101938343B1 (ko) | 2019-01-14 |
JP2014509853A (ja) | 2014-04-24 |
AU2017245395B2 (en) | 2019-05-16 |
AU2017245395A2 (en) | 2017-11-23 |
DK2683736T3 (en) | 2018-04-23 |
CN108220297A (zh) | 2018-06-29 |
AU2017245395A1 (en) | 2017-11-02 |
EP2683736B1 (en) | 2018-01-17 |
KR20190006083A (ko) | 2019-01-16 |
CN103842379A (zh) | 2014-06-04 |
JP2018027090A (ja) | 2018-02-22 |
JP2019195335A (ja) | 2019-11-14 |
US20190002532A1 (en) | 2019-01-03 |
WO2012122484A1 (en) | 2012-09-13 |
AU2019216660A1 (en) | 2019-09-05 |
EP2683736A1 (en) | 2014-01-15 |
CA2829606C (en) | 2020-06-02 |
US20120308555A1 (en) | 2012-12-06 |
KR20190107761A (ko) | 2019-09-20 |
ES2666301T3 (es) | 2018-05-03 |
JP6557709B2 (ja) | 2019-08-07 |
CA2829606A1 (en) | 2012-09-13 |
AU2012225310B2 (en) | 2017-08-03 |
AU2012225310A1 (en) | 2013-09-26 |
HUE037095T2 (hu) | 2018-08-28 |
US9920110B2 (en) | 2018-03-20 |
EP3345922A1 (en) | 2018-07-11 |
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