HK1250373A1 - Alk7:actriib异多聚体和其用途 - Google Patents

Alk7:actriib异多聚体和其用途 Download PDF

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Publication number
HK1250373A1
HK1250373A1 HK18109788.7A HK18109788A HK1250373A1 HK 1250373 A1 HK1250373 A1 HK 1250373A1 HK 18109788 A HK18109788 A HK 18109788A HK 1250373 A1 HK1250373 A1 HK 1250373A1
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Hong Kong
Prior art keywords
heteromultimer
seq
actriib
alk7
amino acid
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HK18109788.7A
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English (en)
Chinese (zh)
Inventor
John Knopf
Ravindra Kumar
Asya Grinberg
Dianne S. Sako
Robert Scott Pearsall
Roselyne CASTONGUAY
Gang Li
Yossi Dagon
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Acceleron Pharma Inc.
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Publication of HK1250373A1 publication Critical patent/HK1250373A1/zh

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    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/71—Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/45—Transferases (2)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y207/00—Transferases transferring phosphorus-containing groups (2.7)
    • C12Y207/11—Protein-serine/threonine kinases (2.7.11)
    • C12Y207/1103—Receptor protein serine/threonine kinase (2.7.11.30)
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    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto

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HK18109788.7A 2015-04-06 2016-04-06 Alk7:actriib异多聚体和其用途 HK1250373A1 (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562143579P 2015-04-06 2015-04-06
US62/143579 2015-04-06
PCT/US2016/026277 WO2016164503A1 (en) 2015-04-06 2016-04-06 Alk7:actriib heteromultimers and uses thereof

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Publication Number Publication Date
HK1250373A1 true HK1250373A1 (zh) 2018-12-14

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Application Number Title Priority Date Filing Date
HK18109788.7A HK1250373A1 (zh) 2015-04-06 2016-04-06 Alk7:actriib异多聚体和其用途
HK18112314.4A HK1252957A1 (zh) 2015-04-06 2016-04-06 TGF-β超家族I型和II型受体异多聚体及其用途

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HK18112314.4A HK1252957A1 (zh) 2015-04-06 2016-04-06 TGF-β超家族I型和II型受体异多聚体及其用途

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US (7) US10227393B2 (enExample)
EP (5) EP3280728B1 (enExample)
JP (3) JP7055636B2 (enExample)
KR (2) KR20180002661A (enExample)
CN (4) CN114736307A (enExample)
AU (4) AU2016246708B2 (enExample)
BR (1) BR112017021510A2 (enExample)
CA (2) CA2981833A1 (enExample)
DK (1) DK3280728T3 (enExample)
EA (2) EA037293B1 (enExample)
ES (1) ES2863564T3 (enExample)
HK (2) HK1250373A1 (enExample)
MA (4) MA41920B1 (enExample)
MX (1) MX391964B (enExample)
WO (2) WO2016164503A1 (enExample)

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