HK1223968A1 - 狂犬病病毒組合物和方法 - Google Patents

狂犬病病毒組合物和方法

Info

Publication number
HK1223968A1
HK1223968A1 HK16111244.3A HK16111244A HK1223968A1 HK 1223968 A1 HK1223968 A1 HK 1223968A1 HK 16111244 A HK16111244 A HK 16111244A HK 1223968 A1 HK1223968 A1 HK 1223968A1
Authority
HK
Hong Kong
Prior art keywords
compositions
methods
rabies virus
rabies
virus
Prior art date
Application number
HK16111244.3A
Other languages
English (en)
Inventor
查爾斯
.盧普里希
吳賢福
Original Assignee
The Government Of The United States Of America As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by The Government Of The United States Of America As filed Critical The Government Of The United States Of America As
Publication of HK1223968A1 publication Critical patent/HK1223968A1/zh

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • A61K39/205Rhabdoviridae, e.g. rabies virus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86Viral vectors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525Virus
    • A61K2039/5254Virus avirulent or attenuated
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011Details
    • C12N2760/20011Rhabdoviridae
    • C12N2760/20111Lyssavirus, e.g. rabies virus
    • C12N2760/20134Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011Details
    • C12N2760/20011Rhabdoviridae
    • C12N2760/20111Lyssavirus, e.g. rabies virus
    • C12N2760/20141Use of virus, viral particle or viral elements as a vector
    • C12N2760/20143Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011Details
    • C12N2760/20011Rhabdoviridae
    • C12N2760/20111Lyssavirus, e.g. rabies virus
    • C12N2760/20161Methods of inactivation or attenuation

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Virology (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biochemistry (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Biophysics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
HK16111244.3A 2005-10-14 2008-12-17 狂犬病病毒組合物和方法 HK1223968A1 (zh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US72703805P 2005-10-14 2005-10-14

Publications (1)

Publication Number Publication Date
HK1223968A1 true HK1223968A1 (zh) 2017-08-11

Family

ID=37775467

Family Applications (2)

Application Number Title Priority Date Filing Date
HK16111244.3A HK1223968A1 (zh) 2005-10-14 2008-12-17 狂犬病病毒組合物和方法
HK08113710.4A HK1123326A1 (zh) 2005-10-14 2008-12-17 狂犬病病毒組合物和方法

Family Applications After (1)

Application Number Title Priority Date Filing Date
HK08113710.4A HK1123326A1 (zh) 2005-10-14 2008-12-17 狂犬病病毒組合物和方法

Country Status (9)

Country Link
US (2) US7863041B2 (zh)
EP (2) EP2351843B1 (zh)
CN (1) CN101287838B (zh)
AU (1) AU2006304268B2 (zh)
BR (1) BRPI0617373B1 (zh)
CA (2) CA2624768C (zh)
HK (2) HK1223968A1 (zh)
WO (1) WO2007047459A1 (zh)
ZA (1) ZA200803131B (zh)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008054544A2 (en) * 2006-05-22 2008-05-08 Immune Disease Institute, Inc. Method for delivery across the blood brain barrier
BRPI0809600B1 (pt) 2007-03-30 2023-01-24 The Research Foundation Of State University Of New York Vírus atenuado útil para vacinas
US8524247B2 (en) 2008-09-17 2013-09-03 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services, Centers For Disease Control And Prevention Rabies virus-based recombinant immunocontraceptive compositions and methods of use
CN101463355B (zh) * 2009-01-15 2011-07-13 中国疾病预防控制中心病毒病预防控制所 狂犬病街毒株hn10全基因组序列及其制备方法和用途
CN101586120B (zh) * 2009-07-15 2011-06-15 中国农业科学院哈尔滨兽医研究所 狂犬病病毒Flury-LEP疫苗株反向遗传操作系统及LEP绿色荧光蛋白重组病毒载体
WO2011048560A1 (en) 2009-10-20 2011-04-28 Novartis Ag Improved reverse genetics methods for virus rescue
WO2013081571A2 (en) * 2010-01-14 2013-06-06 The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services, Centers For Disease Control And Prevention Isolated lyssavirus nucleic acid and protein sequences
EP2585598B1 (en) * 2010-06-24 2015-12-30 THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by the Secretary, Department of Health and Human Services Pan-lyssavirus vaccines against rabies
CN103492574B (zh) 2011-02-22 2015-12-09 加州理工学院 使用腺相关病毒(aav)载体递送蛋白
US9441205B2 (en) 2011-06-08 2016-09-13 Vishwas Joshi Two plasmid mammalian expression system
CN103906843B (zh) * 2011-06-08 2016-12-07 维什瓦斯·乔希 双质粒哺乳动物表达系统
US8689255B1 (en) 2011-09-07 2014-04-01 Imdb.Com, Inc. Synchronizing video content with extrinsic data
US9889192B2 (en) 2012-10-01 2018-02-13 Thomas Jefferson University Immunization with rabies virus vector expressing foreign protein antigen
WO2015069469A1 (en) 2013-11-05 2015-05-14 Clontech Laboratories, Inc. Dry transfection compositions and methods for making and using the same
CN103881985B (zh) * 2014-02-19 2017-10-03 北京中联康生物科技股份有限公司 狂犬病病毒era减毒疫苗突变株及其制备方法和狂犬病活疫苗
CN103877570B (zh) * 2014-02-19 2016-01-20 北京中联康生物科技有限公司 狂犬病活疫苗和制备狂犬病口服活疫苗的方法
RU2626605C2 (ru) * 2015-11-25 2017-07-28 Федеральное Государственное Бюджетное Учреждение Науки Институт Молекулярной Биологии Им. В.А. Энгельгардта Российской Академии Наук (Имб Ран) Генетическая (рекомбинантная) ДНК-конструкция, содержащая кодон-оптимизированный ген гликопротеина (белка G) вируса бешенства с консенсусной аминокислотной последовательностью, которая составлена с учетом аминокислотных последовательностей белка G, выделяемого из штаммов вируса бешенства, циркулирующих на территории Российской Федерации
KR102334083B1 (ko) * 2020-05-04 2021-12-03 대한민국 형광 단백질을 발현하는 재조합 광견병 바이러스 및 이를 이용한 항체 검출 방법

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4040904A (en) * 1975-07-21 1977-08-09 Slater Eban A Novel rabies virus vaccine and processes
US4393201A (en) * 1981-11-04 1983-07-12 The Wistar Institute DNA Which codes for glycoprotein of era-strain rabies virus
AU622426B2 (en) 1987-12-11 1992-04-09 Abbott Laboratories Assay using template-dependent nucleic acid probe reorganization
FR2633832B1 (fr) 1988-07-05 1991-05-31 Virbac Vaccin antirabique avirulent
ATE138106T1 (de) 1988-07-20 1996-06-15 David Segev Verfahren zur amplifizierung und zum nachweis von nukleinsäuresequenzen
US5427930A (en) 1990-01-26 1995-06-27 Abbott Laboratories Amplification of target nucleic acids using gap filling ligase chain reaction
FR2693655B1 (fr) 1992-07-20 1994-10-14 Virbac Vaccin antirabique avirulent.
WO1994027639A1 (en) * 1993-05-26 1994-12-08 Thomas Jefferson University Methods for treating post-exposure rabies and anti-rabies compositions
AU7847094A (en) 1993-09-30 1995-04-18 Thomas Jefferson University Oral vaccination of mammals
US5648211A (en) 1994-04-18 1997-07-15 Becton, Dickinson And Company Strand displacement amplification using thermophilic enzymes
AU711115B2 (en) 1994-07-15 1999-10-07 Akzo Nobel N.V. Use of RNA polymerase to improve nucleic acid amplification process
PT702085E (pt) 1994-07-18 2004-04-30 Karl Klaus Conzelmann Virus de arn de cadeia negativa nao segmentada infeccioso recombinante
US5789229A (en) * 1994-09-30 1998-08-04 Uab Research Foundation Stranded RNA virus particles
AT402203B (de) 1995-06-13 1997-03-25 Himmler Gottfried Dipl Ing Dr Verfahren zur transkriptionsfreien amplifizierung von nucleinsäuren
DK0780475T4 (da) 1995-08-09 2006-10-23 Schweiz Serum & Impfinst Fremgangsmåde til fremstilling af infektiöse negativ-streng RNA-virus
DK1131414T3 (da) * 1998-11-27 2007-06-18 Intervet Int Bv Stabile, svækkede rabiesvirusmutanter og levende vacciner deraf
US20030224017A1 (en) * 2002-03-06 2003-12-04 Samal Siba K. Recombinant Newcastle disease viruses useful as vaccines or vaccine vectors
US7074413B2 (en) * 2000-03-23 2006-07-11 Thomas Jefferson University Genetically engineered rabies recombinant vaccine for immunization of stray dogs and wildlife
JP2004517057A (ja) * 2000-11-03 2004-06-10 オックスフォード バイオメディカ(ユーケイ)リミテッド ベクターシステム
ATE316572T1 (de) 2001-04-23 2006-02-15 Akzo Nobel Nv Attenuierte rekombinante stabile tollwutvirusmutanten und lebendimpfstoffe
CA2454397A1 (en) * 2001-07-20 2003-06-05 The University Of Georgia Research Foundation, Inc. Attenuated rabies virus with nucleoprotein mutation at the phosphorylation site for vaccination against rabies and gene therapy in the cns
EP1439856B1 (en) * 2001-10-10 2009-04-01 Thomas Jefferson University Recombinant rabies vaccine and methods of preparation and use
US9912298B2 (en) 2014-05-13 2018-03-06 Skyworks Solutions, Inc. Systems and methods related to linear load modulated power amplifiers

Also Published As

Publication number Publication date
CA2624768C (en) 2016-10-04
CN101287838B (zh) 2016-03-30
AU2006304268B2 (en) 2011-09-29
HK1123326A1 (zh) 2009-06-12
US20110070264A1 (en) 2011-03-24
BRPI0617373B1 (pt) 2022-04-05
CA2943039A1 (en) 2007-04-26
US7863041B2 (en) 2011-01-04
CA2943039C (en) 2018-11-06
EP2351843A3 (en) 2011-11-09
AU2006304268A2 (en) 2008-06-12
AU2006304268A1 (en) 2007-04-26
US8865461B2 (en) 2014-10-21
CN101287838A (zh) 2008-10-15
BRPI0617373A2 (pt) 2013-01-01
ZA200803131B (en) 2018-11-28
EP1945780B1 (en) 2015-09-16
EP2351843B1 (en) 2013-06-12
EP1945780A1 (en) 2008-07-23
EP2351843A2 (en) 2011-08-03
US20080274130A1 (en) 2008-11-06
WO2007047459A1 (en) 2007-04-26
CA2624768A1 (en) 2007-04-26
WO2007047459A8 (en) 2007-09-20

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