HK1222176A1 - 新型glp-1受体调节剂 - Google Patents

新型glp-1受体调节剂 Download PDF

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Publication number
HK1222176A1
HK1222176A1 HK16110427.4A HK16110427A HK1222176A1 HK 1222176 A1 HK1222176 A1 HK 1222176A1 HK 16110427 A HK16110427 A HK 16110427A HK 1222176 A1 HK1222176 A1 HK 1222176A1
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HK
Hong Kong
Prior art keywords
receptor modulators
novel glp
glp
novel
modulators
Prior art date
Application number
HK16110427.4A
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English (en)
Chinese (zh)
Inventor
F. Boehm Marcus
Martinborough Esther
Moorjani Manisha
Tamiya Junko
Huang Liming
R. YEAGER Adam
Brahmachary Enugurthi
Fowler Thomas
Novak Andrew
Meghani Premji
Knaggs Michael
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Receptos Llc
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Publication of HK1222176A1 publication Critical patent/HK1222176A1/zh

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    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
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    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
    • A—HUMAN NECESSITIES
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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
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    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4453—Non condensed piperidines, e.g. piperocaine only substituted in position 1, e.g. propipocaine, diperodon
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    • A61K31/4985—Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
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    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
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    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
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    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
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  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pyridine Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
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HK16110427.4A 2013-06-11 2014-06-11 新型glp-1受体调节剂 HK1222176A1 (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201361833737P 2013-06-11 2013-06-11
US61/833,737 2013-06-11
US201461981643P 2014-04-18 2014-04-18
US61/981,643 2014-04-18
PCT/US2014/041997 WO2014201172A1 (en) 2013-06-11 2014-06-11 Novel glp-1 receptor modulators

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HK1222176A1 true HK1222176A1 (zh) 2017-06-23

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US (3) US9260427B2 (enExample)
EP (1) EP3008056B8 (enExample)
JP (1) JP6573604B2 (enExample)
KR (1) KR102271179B1 (enExample)
CN (2) CN105593225B (enExample)
AU (1) AU2014278183B2 (enExample)
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