HK1220174A1 - 环己烯酮组成物及其制备方法 - Google Patents

环己烯酮组成物及其制备方法 Download PDF

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Publication number
HK1220174A1
HK1220174A1 HK16108277.9A HK16108277A HK1220174A1 HK 1220174 A1 HK1220174 A1 HK 1220174A1 HK 16108277 A HK16108277 A HK 16108277A HK 1220174 A1 HK1220174 A1 HK 1220174A1
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HK
Hong Kong
Prior art keywords
compound
alkyl
independently
formula
alkynyl
Prior art date
Application number
HK16108277.9A
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English (en)
Chinese (zh)
Inventor
劉勝勇
刘胜勇
溫武哲
温武哲
陳志銘
陈志铭
鄭秀宜
郑秀宜
Original Assignee
国鼎生物科技股份有限公司
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Publication of HK1220174A1 publication Critical patent/HK1220174A1/zh

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C403/00—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone
    • C07C403/02—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains containing only carbon and hydrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C403/00—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone
    • C07C403/20—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by carboxyl groups or halides, anhydrides, or (thio)esters thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/587—Unsaturated compounds containing a keto groups being part of a ring
    • C07C49/753—Unsaturated compounds containing a keto groups being part of a ring containing ether groups, groups, groups, or groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/04—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D307/18—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/20—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/26—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D307/30—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/32—Oxygen atoms
    • C07D307/33—Oxygen atoms in position 2, the oxygen atom being in its keto or unsubstituted enol form
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
HK16108277.9A 2013-02-20 2014-02-20 环己烯酮组成物及其制备方法 HK1220174A1 (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361767212P 2013-02-20 2013-02-20
US61/767,212 2013-02-20
PCT/US2014/017284 WO2014130618A1 (en) 2013-02-20 2014-02-20 Cyclohexenone compositions and process for making thereof

Publications (1)

Publication Number Publication Date
HK1220174A1 true HK1220174A1 (zh) 2017-04-28

Family

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Family Applications (1)

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HK16108277.9A HK1220174A1 (zh) 2013-02-20 2014-02-20 环己烯酮组成物及其制备方法

Country Status (9)

Country Link
US (2) US9365481B2 (enExample)
EP (1) EP2958883B1 (enExample)
JP (2) JP6706018B2 (enExample)
CN (1) CN105263893A (enExample)
CA (1) CA2901581C (enExample)
ES (1) ES2713181T3 (enExample)
HK (1) HK1220174A1 (enExample)
TW (1) TWI612026B (enExample)
WO (1) WO2014130618A1 (enExample)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI612026B (zh) * 2013-02-20 2018-01-21 國鼎生物科技股份有限公司 環己烯酮組成物及其製造方法
WO2016037566A1 (en) * 2014-09-09 2016-03-17 Ching-Feng Weng Use of antroqiononol for treating obesity, and process for preparation of antroquinonol
US20160237012A1 (en) * 2015-02-17 2016-08-18 Golden Biotechnology Corporation Anticancer agents and process of making thereof
CN109069448B (zh) * 2016-02-17 2021-09-21 国鼎生物科技股份有限公司 用于治疗肝癌的组合物和方法
TW201831436A (zh) * 2017-02-24 2018-09-01 郭盈妤 分離自牛樟芝的化合物及其用途
AU2018247249B2 (en) 2017-12-20 2023-10-19 Golden Biotechnology Corporation Therapeutic compositions for treating pancreatic cancer
US11406605B2 (en) 2017-12-20 2022-08-09 Golden Biotechnology Corporation Therapeutic compositions for treating pancreatic cancer
CN111018686B (zh) * 2019-11-19 2020-09-22 南通大学 6-苄亚基-2-芳基乙炔基环己烯酮衍生物及其制备方法和医药用途
MX2022013955A (es) 2020-05-08 2023-02-23 Golden Biotechnology Corp Metodos y composiciones para tratar una enfermedad inducida por virus de arn.
WO2025165622A1 (en) * 2024-01-31 2025-08-07 Golden Biotechnology Corporation Therapeutic compositions for treating liver cancer

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW200829234A (en) * 2007-01-08 2008-07-16 Golden Biotechnology Corp Antrodia camphorata isophorone extract
CN101417934B (zh) * 2007-10-24 2012-04-18 国鼎生物科技股份有限公司 分离自牛樟芝萃取物的化合物
TWI389699B (zh) * 2009-02-13 2013-03-21 高雄醫學大學 用於誘導細胞凋亡之樟芝子實體乙醇萃取物及其製備方法
TWI394566B (zh) * 2009-09-09 2013-05-01 國鼎生物科技股份有限公司 Used to inhibit the growth of ovarian cancer tumor cells of the cattle camphor cyclohexene ketone compounds
TW201109023A (en) * 2009-09-09 2011-03-16 Golden Biotechnology Corp Cyclohexenone compound of Antrodia cinnomomea that suppresses growth of tumor cell of colorectal cancer
TW201109013A (en) * 2009-09-09 2011-03-16 Golden Biotechnology Corp Cyclohexenone chemical compounds of Antrodia cinnamomea for suppressing the growth of the Lymphoma tumor cell
US8309611B2 (en) * 2010-09-20 2012-11-13 Golden Biotechnology Corporation Methods and compositions for treating lung cancer
TWI444189B (zh) * 2011-05-31 2014-07-11 Mackay Memorial Hospital 羊毛甾醇－８，２４－二烯－３β，１５α，２１－三醇抑制腫瘤細胞生長之用途
AR086865A1 (es) * 2011-06-10 2014-01-29 Golden Biotechnology Corp Metodos y composiciones para el tratamiento del cancer de cerebro
TWI612026B (zh) * 2013-02-20 2018-01-21 國鼎生物科技股份有限公司 環己烯酮組成物及其製造方法

Also Published As

Publication number Publication date
EP2958883B1 (en) 2019-01-30
CA2901581A1 (en) 2014-08-28
US20160251308A1 (en) 2016-09-01
ES2713181T3 (es) 2019-05-20
US9365481B2 (en) 2016-06-14
JP6706018B2 (ja) 2020-06-03
WO2014130618A1 (en) 2014-08-28
JP2019142854A (ja) 2019-08-29
EP2958883A1 (en) 2015-12-30
TWI612026B (zh) 2018-01-21
EP2958883A4 (en) 2016-08-17
CA2901581C (en) 2020-07-14
US20150018567A1 (en) 2015-01-15
CN105263893A (zh) 2016-01-20
JP2016513122A (ja) 2016-05-12
TW201500330A (zh) 2015-01-01

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