ES2713181T3 - Composiciones de ciclohexenona y proceso para hacerla - Google Patents

Composiciones de ciclohexenona y proceso para hacerla Download PDF

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Publication number
ES2713181T3
ES2713181T3 ES14754902T ES14754902T ES2713181T3 ES 2713181 T3 ES2713181 T3 ES 2713181T3 ES 14754902 T ES14754902 T ES 14754902T ES 14754902 T ES14754902 T ES 14754902T ES 2713181 T3 ES2713181 T3 ES 2713181T3
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ES
Spain
Prior art keywords
compound
acid
alkyl
groups
compounds
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES14754902T
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English (en)
Spanish (es)
Inventor
Sheng-Yung Liu
Wu-Che Wen
Chih-Ming Chen
Hsiu-Yi Cheng
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Golden Biotechnology Corp
Original Assignee
Golden Biotechnology Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
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Publication of ES2713181T3 publication Critical patent/ES2713181T3/es
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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C403/00—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone
    • C07C403/02—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains containing only carbon and hydrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C403/00—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone
    • C07C403/20—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by carboxyl groups or halides, anhydrides, or (thio)esters thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/587—Unsaturated compounds containing a keto groups being part of a ring
    • C07C49/753—Unsaturated compounds containing a keto groups being part of a ring containing ether groups, groups, groups, or groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/04—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D307/18—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/20—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/26—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D307/30—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/32—Oxygen atoms
    • C07D307/33—Oxygen atoms in position 2, the oxygen atom being in its keto or unsubstituted enol form
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ES14754902T 2013-02-20 2014-02-20 Composiciones de ciclohexenona y proceso para hacerla Active ES2713181T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361767212P 2013-02-20 2013-02-20
PCT/US2014/017284 WO2014130618A1 (en) 2013-02-20 2014-02-20 Cyclohexenone compositions and process for making thereof

Publications (1)

Publication Number Publication Date
ES2713181T3 true ES2713181T3 (es) 2019-05-20

Family

ID=51391788

Family Applications (1)

Application Number Title Priority Date Filing Date
ES14754902T Active ES2713181T3 (es) 2013-02-20 2014-02-20 Composiciones de ciclohexenona y proceso para hacerla

Country Status (9)

Country Link
US (2) US9365481B2 (enExample)
EP (1) EP2958883B1 (enExample)
JP (2) JP6706018B2 (enExample)
CN (1) CN105263893A (enExample)
CA (1) CA2901581C (enExample)
ES (1) ES2713181T3 (enExample)
HK (1) HK1220174A1 (enExample)
TW (1) TWI612026B (enExample)
WO (1) WO2014130618A1 (enExample)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI612026B (zh) * 2013-02-20 2018-01-21 國鼎生物科技股份有限公司 環己烯酮組成物及其製造方法
TW201632491A (zh) * 2014-09-09 2016-09-16 翁慶豐 安卓奎諾爾於治療肥胖的用途及製備安卓奎諾爾的方法
US20160237012A1 (en) * 2015-02-17 2016-08-18 Golden Biotechnology Corporation Anticancer agents and process of making thereof
KR102399856B1 (ko) * 2016-02-17 2022-05-20 골든 바이오테크놀러지 코포레이션 간암 치료용 조성물 및 방법
TW201831436A (zh) * 2017-02-24 2018-09-01 郭盈妤 分離自牛樟芝的化合物及其用途
AU2018247249B2 (en) 2017-12-20 2023-10-19 Golden Biotechnology Corporation Therapeutic compositions for treating pancreatic cancer
US11406605B2 (en) 2017-12-20 2022-08-09 Golden Biotechnology Corporation Therapeutic compositions for treating pancreatic cancer
CN111018686B (zh) * 2019-11-19 2020-09-22 南通大学 6-苄亚基-2-芳基乙炔基环己烯酮衍生物及其制备方法和医药用途
CA3168432A1 (en) 2020-05-08 2021-11-11 Golden Biotechnology Corporation Methods and compositions for treating an rna virus induced disease
WO2025165622A1 (en) * 2024-01-31 2025-08-07 Golden Biotechnology Corporation Therapeutic compositions for treating liver cancer

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW200829234A (en) * 2007-01-08 2008-07-16 Golden Biotechnology Corp Antrodia camphorata isophorone extract
CN101417934B (zh) * 2007-10-24 2012-04-18 国鼎生物科技股份有限公司 分离自牛樟芝萃取物的化合物
TWI389699B (zh) * 2009-02-13 2013-03-21 高雄醫學大學 用於誘導細胞凋亡之樟芝子實體乙醇萃取物及其製備方法
TW201109013A (en) * 2009-09-09 2011-03-16 Golden Biotechnology Corp Cyclohexenone chemical compounds of Antrodia cinnamomea for suppressing the growth of the Lymphoma tumor cell
TWI394566B (zh) * 2009-09-09 2013-05-01 國鼎生物科技股份有限公司 Used to inhibit the growth of ovarian cancer tumor cells of the cattle camphor cyclohexene ketone compounds
TW201109023A (en) * 2009-09-09 2011-03-16 Golden Biotechnology Corp Cyclohexenone compound of Antrodia cinnomomea that suppresses growth of tumor cell of colorectal cancer
US8309611B2 (en) * 2010-09-20 2012-11-13 Golden Biotechnology Corporation Methods and compositions for treating lung cancer
TWI444189B (zh) * 2011-05-31 2014-07-11 財團法人台灣基督長老教會馬偕紀念社會事業基金會馬偕紀念醫院 羊毛甾醇－８，２４－二烯－３β，１５α，２１－三醇抑制腫瘤細胞生長之用途
CN103796647A (zh) * 2011-06-10 2014-05-14 国鼎生物科技股份有限公司 用于治疗脑癌的方法和组合物
TWI612026B (zh) * 2013-02-20 2018-01-21 國鼎生物科技股份有限公司 環己烯酮組成物及其製造方法

Also Published As

Publication number Publication date
JP2019142854A (ja) 2019-08-29
WO2014130618A1 (en) 2014-08-28
HK1220174A1 (zh) 2017-04-28
CA2901581C (en) 2020-07-14
EP2958883A1 (en) 2015-12-30
EP2958883A4 (en) 2016-08-17
US20160251308A1 (en) 2016-09-01
TWI612026B (zh) 2018-01-21
EP2958883B1 (en) 2019-01-30
US9365481B2 (en) 2016-06-14
TW201500330A (zh) 2015-01-01
US20150018567A1 (en) 2015-01-15
JP6706018B2 (ja) 2020-06-03
CA2901581A1 (en) 2014-08-28
CN105263893A (zh) 2016-01-20
JP2016513122A (ja) 2016-05-12

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