HK1212377A1 - Sirna and their use in methods and compositions for the treatment and/or prevention of eye conditions sirna / - Google Patents

Sirna and their use in methods and compositions for the treatment and/or prevention of eye conditions sirna /

Info

Publication number
HK1212377A1
HK1212377A1 HK16100039.5A HK16100039A HK1212377A1 HK 1212377 A1 HK1212377 A1 HK 1212377A1 HK 16100039 A HK16100039 A HK 16100039A HK 1212377 A1 HK1212377 A1 HK 1212377A1
Authority
HK
Hong Kong
Prior art keywords
sirna
prevention
compositions
treatment
methods
Prior art date
Application number
HK16100039.5A
Other languages
English (en)
Chinese (zh)
Inventor
Fajardo Victoria Gonzalez
Anton Ana Isabel Jimenez
Palomar Veronica Ruz
Original Assignee
Sylentis Sau
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sylentis Sau filed Critical Sylentis Sau
Publication of HK1212377A1 publication Critical patent/HK1212377A1/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088—Compounds having three or more nucleosides or nucleotides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/04—Artificial tears; Irrigation solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A61P29/02—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • C12N15/1138—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against receptors or cell surface proteins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/10—Type of nucleic acid
    • C12N2310/14—Type of nucleic acid interfering N.A.
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/30—Chemical structure
    • C12N2310/32—Chemical structure of the sugar
    • C12N2310/321—2'-O-R Modification

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Biochemistry (AREA)
  • Plant Pathology (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Ophthalmology & Optometry (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
HK16100039.5A 2012-09-05 2016-01-05 Sirna and their use in methods and compositions for the treatment and/or prevention of eye conditions sirna / HK1212377A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB1215857.2A GB201215857D0 (en) 2012-09-05 2012-09-05 siRNA and their use in methods and compositions for the treatment and/or prevention of eye conditions
PCT/EP2013/068245 WO2014037377A1 (en) 2012-09-05 2013-09-04 Sirna and their use in methods and compositions for the treatment and/or prevention of eye conditions

Publications (1)

Publication Number Publication Date
HK1212377A1 true HK1212377A1 (en) 2016-06-10

Family

ID=47136985

Family Applications (1)

Application Number Title Priority Date Filing Date
HK16100039.5A HK1212377A1 (en) 2012-09-05 2016-01-05 Sirna and their use in methods and compositions for the treatment and/or prevention of eye conditions sirna /

Country Status (30)

Country Link
US (1) US9808479B2 (hr)
EP (1) EP2893019B1 (hr)
JP (2) JP2015529210A (hr)
KR (1) KR102136539B1 (hr)
CN (2) CN104640988A (hr)
AU (1) AU2013311781B2 (hr)
BR (1) BR112015004469B8 (hr)
CA (1) CA2883040C (hr)
CL (1) CL2015000537A1 (hr)
CY (1) CY1121000T1 (hr)
DK (1) DK2893019T3 (hr)
EC (1) ECSP15009391A (hr)
ES (1) ES2685346T3 (hr)
GB (1) GB201215857D0 (hr)
HK (1) HK1212377A1 (hr)
HR (1) HRP20181079T1 (hr)
HU (1) HUE040096T2 (hr)
IL (1) IL237389B (hr)
IN (1) IN2015DN02501A (hr)
LT (1) LT2893019T (hr)
MX (1) MX362854B (hr)
PE (1) PE20150619A1 (hr)
PL (1) PL2893019T3 (hr)
PT (1) PT2893019T (hr)
RS (1) RS57620B1 (hr)
RU (1) RU2663100C2 (hr)
SG (1) SG11201501386TA (hr)
SI (1) SI2893019T1 (hr)
WO (1) WO2014037377A1 (hr)
ZA (1) ZA201501494B (hr)

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KR20180038465A (ko) 2015-08-07 2018-04-16 애로우헤드 파마슈티컬스 인코포레이티드 Ｂ형 간염 바이러스 감염에 대한 ｒｎａｉ 치료법
JOP20170161A1 (ar) 2016-08-04 2019-01-30 Arrowhead Pharmaceuticals Inc عوامل RNAi للعدوى بفيروس التهاب الكبد ب
JP6994061B2 (ja) 2019-02-15 2022-01-14 ノバルティス アーゲー ４－（７－ヒドロキシ－２－イソプロピル－４－オキソ－４ｈ－キナゾリン－３－イル）－ベンゾニトリルの製剤
JP2022520832A (ja) 2019-02-15 2022-04-01 ノバルティス アーゲー 眼表面疼痛を治療する方法
CA3156484A1 (en) * 2019-10-04 2021-04-08 Senju Pharmaceutical Co., Ltd. PHARMACEUTICAL MEDICINAL PRODUCT CONTAINING A HETEROCYCLIDENE ACETAMIDE DERIVATIVE

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Also Published As

Publication number Publication date
KR20150047513A (ko) 2015-05-04
MX2015002802A (es) 2015-05-15
IN2015DN02501A (hr) 2015-09-11
JP2018138596A (ja) 2018-09-06
ECSP15009391A (es) 2015-12-31
PL2893019T3 (pl) 2018-12-31
RU2663100C2 (ru) 2018-08-01
CN108354944A (zh) 2018-08-03
ES2685346T3 (es) 2018-10-08
PE20150619A1 (es) 2015-05-11
RU2015112121A (ru) 2016-10-27
PT2893019T (pt) 2018-10-19
CY1121000T1 (el) 2019-12-11
IL237389B (en) 2019-01-31
EP2893019B1 (en) 2018-05-30
AU2013311781A1 (en) 2015-03-12
WO2014037377A1 (en) 2014-03-13
KR102136539B1 (ko) 2020-07-23
MX362854B (es) 2019-02-20
JP2015529210A (ja) 2015-10-05
CL2015000537A1 (es) 2015-07-10
IL237389A0 (en) 2015-04-30
GB201215857D0 (en) 2012-10-24
CA2883040C (en) 2023-01-17
US20150224131A1 (en) 2015-08-13
JP6742362B2 (ja) 2020-08-19
BR112015004469B8 (pt) 2022-12-06
SI2893019T1 (sl) 2018-09-28
AU2013311781B2 (en) 2018-10-18
EP2893019A1 (en) 2015-07-15
RS57620B1 (sr) 2018-11-30
HRP20181079T1 (hr) 2018-09-07
SG11201501386TA (en) 2015-03-30
US9808479B2 (en) 2017-11-07
ZA201501494B (en) 2016-01-27
DK2893019T3 (en) 2018-09-03
BR112015004469A2 (pt) 2017-08-08
CN104640988A (zh) 2015-05-20
LT2893019T (lt) 2018-08-10
CA2883040A1 (en) 2014-03-13
BR112015004469B1 (pt) 2022-11-16
HUE040096T2 (hu) 2019-02-28

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