HK1211474A1 - Treatment of immune-related and inflammatory diseases - Google Patents

Treatment of immune-related and inflammatory diseases

Info

Publication number
HK1211474A1
HK1211474A1 HK15112280.7A HK15112280A HK1211474A1 HK 1211474 A1 HK1211474 A1 HK 1211474A1 HK 15112280 A HK15112280 A HK 15112280A HK 1211474 A1 HK1211474 A1 HK 1211474A1
Authority
HK
Hong Kong
Prior art keywords
immune
treatment
inflammatory diseases
inflammatory
diseases
Prior art date
Application number
HK15112280.7A
Other languages
English (en)
Chinese (zh)
Inventor
彼得‧
‧謝弗
拉傑什‧喬普拉
阿尼塔‧甘地
Original Assignee
Celgene Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Celgene Corp filed Critical Celgene Corp
Publication of HK1211474A1 publication Critical patent/HK1211474A1/xx

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/53751,4-Oxazines, e.g. morpholine
    • A61K31/53771,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Transplantation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
HK15112280.7A 2012-08-09 2015-12-14 Treatment of immune-related and inflammatory diseases HK1211474A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261681491P 2012-08-09 2012-08-09
US201261722718P 2012-11-05 2012-11-05
PCT/US2013/054051 WO2014025958A2 (en) 2012-08-09 2013-08-08 Treatment of immune-related and inflammatory diseases

Publications (1)

Publication Number Publication Date
HK1211474A1 true HK1211474A1 (en) 2016-05-27

Family

ID=49029213

Family Applications (1)

Application Number Title Priority Date Filing Date
HK15112280.7A HK1211474A1 (en) 2012-08-09 2015-12-14 Treatment of immune-related and inflammatory diseases

Country Status (30)

Country Link
US (2) US10919883B2 (xx)
EP (2) EP3741372A1 (xx)
JP (2) JP6250671B2 (xx)
KR (3) KR20210073616A (xx)
CN (4) CN114939119A (xx)
AU (1) AU2013299625B2 (xx)
BR (1) BR112015002272A2 (xx)
CA (2) CA3092279C (xx)
CY (1) CY1123106T1 (xx)
DK (1) DK2882441T3 (xx)
EA (1) EA029085B1 (xx)
ES (1) ES2800026T3 (xx)
HK (1) HK1211474A1 (xx)
HR (1) HRP20200836T1 (xx)
HU (1) HUE049569T2 (xx)
IL (1) IL237070B (xx)
LT (1) LT2882441T (xx)
MX (1) MX2015001686A (xx)
NI (1) NI201500013A (xx)
NZ (2) NZ727295A (xx)
PH (1) PH12015500276A1 (xx)
PL (1) PL2882441T3 (xx)
PT (1) PT2882441T (xx)
RS (1) RS60416B1 (xx)
SG (1) SG11201500983RA (xx)
SI (1) SI2882441T1 (xx)
TW (1) TWI641371B (xx)
UA (1) UA116992C2 (xx)
WO (1) WO2014025958A2 (xx)
ZA (1) ZA201500466B (xx)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2730763T3 (es) 2010-02-11 2019-11-12 Celgene Corp Derivados de arilmetoxi isoindolina y composiciones que los comprenden y métodos de uso de los mismos
AU2012236655B2 (en) 2011-03-28 2016-09-22 Deuterx, Llc, 2',6'-dioxo-3'-deutero-piperdin-3-yl-isoindoline compounds
US20150038511A1 (en) 2012-08-09 2015-02-05 Celgene Corporation Treatment of immune-related and inflammatory diseases
US9540340B2 (en) 2013-01-14 2017-01-10 Deuterx, Llc 3-(5-substituted-4-oxoquinazolin-3(4H)-yl)-3-deutero-piperidine-2,6-dione derivatives and compositions comprising and methods of using the same
WO2014116573A1 (en) 2013-01-22 2014-07-31 Celgene Corporation Processes for the preparation of isotopologues of 3-(4-((4-(morpholinomethyl)benzyl)oxy)-1-oxoisoindolin-2-yl)piperidine-2,6-dione and pharmaceutically acceptable salts thereof
EP2968334A4 (en) 2013-03-14 2016-08-03 Deuterx Llc 3- (SUBSTITIERTES-4-OXO-quinazolin-3 (4H) -yl) -3-deutero-PIPERIDINE-2,6-DIONE DERIVATIVES
WO2015179279A1 (en) * 2014-05-19 2015-11-26 Celgene Corporation Treatment of immune-related and inflammatory diseases
JP2017522270A (ja) * 2014-05-19 2017-08-10 セルジーン コーポレイション 全身性エリテマトーデスの治療のための3−(4−((4−(モルホリノメチル−ベンジル)オキシ)−1−オキソイソインドリン−2−イル)ピペリジン−2,6−ジオン
US9809603B1 (en) 2015-08-18 2017-11-07 Deuterx, Llc Deuterium-enriched isoindolinonyl-piperidinonyl conjugates and oxoquinazolin-3(4H)-yl-piperidinonyl conjugates and methods of treating medical disorders using same
DK3496739T3 (da) 2016-07-15 2021-05-10 Acceleron Pharma Inc Sammensætninger omfattende actriia-polypeptider til brug i behandlingen af pulmonal hypertension
AU2019272751B2 (en) * 2018-05-23 2024-08-15 Celgene Corporation Treating multiple myeloma and the use of biomarkers for 4-(4-(4-(((2-(2,6-dioxopiperidin-3-yl)-1- oxoisoindolin-4-yl)oxy)methyl)benzyl) piperazin-1-yl)-3-fluorobenzonitrile
AU2019351811A1 (en) 2018-10-01 2021-05-06 Celgene Corporation Combination therapy for the treatment of cancer
MX2021009079A (es) * 2019-01-28 2022-02-10 Sanofi Sa Metodos para tratar el mieloma multiple.
US11609233B2 (en) 2019-03-28 2023-03-21 Alentic Microscience Inc. Indicator-based analysis of a sample
US10684278B1 (en) * 2019-03-28 2020-06-16 Alentic Microscience Inc. Bead-based analysis of a sample
US11719700B2 (en) 2019-03-28 2023-08-08 Alentic Microscience Inc. Upconversion for microscopy
US11255850B2 (en) 2019-03-28 2022-02-22 Alentic Microscience Inc. Bead-based analysis of a sample
US20210154193A1 (en) * 2019-11-25 2021-05-27 PHPrecisionMed, LLC Pharmaceutical compositions for the treatment of pulmonary hypertension
WO2023097111A2 (en) * 2021-11-29 2023-06-01 Riptide Bioscience, Inc. Methods and compositions for treating calcinosis associated conditions
WO2024064646A1 (en) 2022-09-20 2024-03-28 Celgene Corporation Salts and solid forms of (s)- or racemic 3-(4-((4-(morpholinomethyl)benzyl)oxy)-1-oxoisoindolin-2-yl)piperidine-2,6-dione and methods of using the same

Family Cites Families (61)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3536809A (en) 1969-02-17 1970-10-27 Alza Corp Medication method
US3598123A (en) 1969-04-01 1971-08-10 Alza Corp Bandage for administering drugs
US3845770A (en) 1972-06-05 1974-11-05 Alza Corp Osmatic dispensing device for releasing beneficial agent
US3916899A (en) 1973-04-25 1975-11-04 Alza Corp Osmotic dispensing device with maximum and minimum sizes for the passageway
US4008719A (en) 1976-02-02 1977-02-22 Alza Corporation Osmotic system having laminar arrangement for programming delivery of active agent
ES8702440A1 (es) 1984-10-04 1986-12-16 Monsanto Co Un procedimiento para la preparacion de una composicion de polipeptido inyectable sustancialmente no acuosa.
IE58110B1 (en) 1984-10-30 1993-07-14 Elan Corp Plc Controlled release powder and process for its preparation
US5073543A (en) 1988-07-21 1991-12-17 G. D. Searle & Co. Controlled release formulations of trophic factors in ganglioside-lipsome vehicle
IT1229203B (it) 1989-03-22 1991-07-25 Bioresearch Spa Impiego di acido 5 metiltetraidrofolico, di acido 5 formiltetraidrofolico e dei loro sali farmaceuticamente accettabili per la preparazione di composizioni farmaceutiche in forma a rilascio controllato attive nella terapia dei disturbi mentali organici e composizioni farmaceutiche relative.
PH30995A (en) 1989-07-07 1997-12-23 Novartis Inc Sustained release formulations of water soluble peptides.
US5120548A (en) 1989-11-07 1992-06-09 Merck & Co., Inc. Swelling modulated polymeric drug delivery device
KR0166088B1 (ko) 1990-01-23 1999-01-15 . 수용해도가 증가된 시클로덱스트린 유도체 및 이의 용도
US5733566A (en) 1990-05-15 1998-03-31 Alkermes Controlled Therapeutics Inc. Ii Controlled release of antiparasitic agents in animals
US5580578A (en) 1992-01-27 1996-12-03 Euro-Celtique, S.A. Controlled release formulations coated with aqueous dispersions of acrylic polymers
TW333456B (en) 1992-12-07 1998-06-11 Takeda Pharm Ind Co Ltd A pharmaceutical composition of sustained-release preparation the invention relates to a pharmaceutical composition of sustained-release preparation which comprises a physiologically active peptide.
US5591767A (en) 1993-01-25 1997-01-07 Pharmetrix Corporation Liquid reservoir transdermal patch for the administration of ketorolac
US6087324A (en) 1993-06-24 2000-07-11 Takeda Chemical Industries, Ltd. Sustained-release preparation
IT1270594B (it) 1994-07-07 1997-05-07 Recordati Chem Pharm Composizione farmaceutica a rilascio controllato di moguisteina in sospensione liquida
CA2224381A1 (en) 1995-06-27 1997-01-16 Takeda Chemical Industries, Ltd. Method of producing sustained-release preparation
TW448055B (en) 1995-09-04 2001-08-01 Takeda Chemical Industries Ltd Method of production of sustained-release preparation
JP2909418B2 (ja) 1995-09-18 1999-06-23 株式会社資生堂 薬物の遅延放出型マイクロスフイア
US5980945A (en) 1996-01-16 1999-11-09 Societe De Conseils De Recherches Et D'applications Scientifique S.A. Sustained release drug formulations
US6264970B1 (en) 1996-06-26 2001-07-24 Takeda Chemical Industries, Ltd. Sustained-release preparation
US5635517B1 (en) 1996-07-24 1999-06-29 Celgene Corp Method of reducing TNFalpha levels with amino substituted 2-(2,6-dioxopiperidin-3-YL)-1-oxo-and 1,3-dioxoisoindolines
US6419961B1 (en) 1996-08-29 2002-07-16 Takeda Chemical Industries, Ltd. Sustained release microcapsules of a bioactive substance and a biodegradable polymer
CA2217134A1 (en) 1996-10-09 1998-04-09 Sumitomo Pharmaceuticals Co., Ltd. Sustained release formulation
ATE272394T1 (de) 1996-10-31 2004-08-15 Takeda Chemical Industries Ltd Zubereitung mit verzögerter freisetzung
ZA9711385B (en) 1996-12-20 1999-06-18 Takeda Chemical Industries Ltd Method of producing a sustained-release preparation
US5891474A (en) 1997-01-29 1999-04-06 Poli Industria Chimica, S.P.A. Time-specific controlled release dosage formulations and method of preparing same
TR200101501T2 (tr) 1998-03-16 2002-06-21 Celgene Corporation 2-(2,6-dioksopiperidin-3-il)izoindolin türevleri, bunların hazırlanması ve enflamatuar sitokinlerin inhibitörleri olarak kullanımı.
US6613358B2 (en) 1998-03-18 2003-09-02 Theodore W. Randolph Sustained-release composition including amorphous polymer
KR19990085365A (ko) 1998-05-16 1999-12-06 허영섭 지속적으로 약물 조절방출이 가능한 생분해성 고분자 미립구 및그 제조방법
US6248363B1 (en) 1999-11-23 2001-06-19 Lipocine, Inc. Solid carriers for improved delivery of active ingredients in pharmaceutical compositions
US6984522B2 (en) 2000-08-03 2006-01-10 Regents Of The University Of Michigan Isolation and use of solid tumor stem cells
CA2418835A1 (en) 2000-10-16 2002-04-25 Phylos, Inc. Protein scaffolds for antibody mimics and other binding proteins
US20030133939A1 (en) 2001-01-17 2003-07-17 Genecraft, Inc. Binding domain-immunoglobulin fusion proteins
US7754208B2 (en) 2001-01-17 2010-07-13 Trubion Pharmaceuticals, Inc. Binding domain-immunoglobulin fusion proteins
US20030082630A1 (en) 2001-04-26 2003-05-01 Maxygen, Inc. Combinatorial libraries of monomer domains
GB0120441D0 (en) 2001-08-22 2001-10-17 Novartis Forschungsstiftung Model of autoimmune disease and methods for identifying anti autoimmune disease disorders
US7173032B2 (en) 2001-09-21 2007-02-06 Reddy Us Therapeutics, Inc. Methods and compositions of novel triazine compounds
US20060234299A1 (en) 2004-11-16 2006-10-19 Avidia Research Institute Protein scaffolds and uses thereof
US8088591B2 (en) 2006-05-12 2012-01-03 University Of Miami Biomarkers for detection and diagnosis of head and neck squamous cell carcinoma
US20080045485A1 (en) 2006-08-17 2008-02-21 Peter Muir Methods of diagnosing synovial disease in a mammal by detecting bacterial DNA in synovial tissues from dogs with inflammatory knee arthritis and degenerative anterior cruciate ligament rupture
MX2009006304A (es) * 2006-12-15 2009-06-23 Abbott Lab Nuevos compuestos de oxadiazol.
WO2008115516A2 (en) 2007-03-20 2008-09-25 Celgene Corporation 4'-o-substituted isoindoline derivatives and compositions comprising and methods of using the same
CN101680887B (zh) 2007-03-30 2014-06-25 褚圣-贾斯汀公司 测定脊柱侧凸风险的方法
JP5442185B2 (ja) * 2007-04-24 2014-03-12 日本メナード化粧品株式会社 感作性物質評価方法
CA2720184C (en) 2008-03-31 2017-07-18 Boston Medical Center Corporation Predictive marker for topoisomerase i inhibitors
JP2011522515A (ja) * 2008-04-10 2011-08-04 マサチューセッツ インスティテュート オブ テクノロジー 癌幹細胞を標的とする薬剤を同定する方法およびその使用
CN106008322B (zh) 2008-12-05 2018-09-04 Abbvie 公司 作为用于治疗癌症和免疫疾病的bcl-2-选择性诱发细胞凋亡药剂的磺酰胺衍生物
JP5836929B2 (ja) 2009-04-18 2015-12-24 ジェネンテック, インコーポレイテッド 抗cd40抗体を用いる治療に対するb細胞性リンパ腫の応答性を評価するための方法
ES2730763T3 (es) 2010-02-11 2019-11-12 Celgene Corp Derivados de arilmetoxi isoindolina y composiciones que los comprenden y métodos de uso de los mismos
JP5808349B2 (ja) 2010-03-01 2015-11-10 カリス ライフ サイエンシズ スウィッツァーランド ホールディングスゲーエムベーハー セラノーシスのためのバイオマーカー
CA2808417A1 (en) 2010-08-18 2012-02-23 Caris Life Sciences Luxembourg Holdings, S.A.R.L. Circulating biomarkers for disease
WO2012115885A1 (en) 2011-02-22 2012-08-30 Caris Life Sciences Luxembourg Holdings, S.A.R.L. Circulating biomarkers
BR112013032232A2 (pt) * 2011-06-16 2016-09-20 Caris Life Sciences Switzerland Holdings S A R L método de caracterização de câncer através do uso de biomarcador de ácido nucleico
EP2867671B1 (en) 2012-06-29 2018-10-24 Celgene Corporation Methods for determining drug efficacy using cereblon-associated proteins
US20150038511A1 (en) 2012-08-09 2015-02-05 Celgene Corporation Treatment of immune-related and inflammatory diseases
US20140343058A1 (en) 2012-08-09 2014-11-20 Celgene Corporation Treatment of systemic lupus erythematosus
UA117141C2 (uk) 2013-10-08 2018-06-25 Селджин Корпорейшн Склади (s)-3-(4-((4-(морфолінометил)бензил)оксі)-1-оксоізоіндолін-2-іл)піперидин-2,6-діону
JP2017522270A (ja) 2014-05-19 2017-08-10 セルジーン コーポレイション 全身性エリテマトーデスの治療のための3−(4−((4−(モルホリノメチル−ベンジル)オキシ)−1−オキソイソインドリン−2−イル)ピペリジン−2,6−ジオン

Also Published As

Publication number Publication date
CN108938642A (zh) 2018-12-07
EP2882441B1 (en) 2020-04-29
NI201500013A (es) 2019-05-10
NZ727295A (en) 2018-06-29
US20140045844A1 (en) 2014-02-13
CA3092279C (en) 2023-08-08
WO2014025958A2 (en) 2014-02-13
MX2015001686A (es) 2015-04-10
PH12015500276A1 (en) 2015-04-27
CN104703605A (zh) 2015-06-10
KR20210073616A (ko) 2021-06-18
JP2018070623A (ja) 2018-05-10
US10919883B2 (en) 2021-02-16
DK2882441T3 (da) 2020-05-25
IL237070A0 (en) 2015-03-31
PL2882441T3 (pl) 2020-09-21
RS60416B1 (sr) 2020-07-31
TWI641371B (zh) 2018-11-21
BR112015002272A2 (pt) 2017-07-04
PT2882441T (pt) 2020-06-29
KR20200058606A (ko) 2020-05-27
UA116992C2 (uk) 2018-06-11
EA201590342A1 (ru) 2015-07-30
HUE049569T2 (hu) 2020-09-28
CA3092279A1 (en) 2014-02-13
HRP20200836T1 (hr) 2020-08-07
WO2014025958A3 (en) 2014-04-17
EP3741372A1 (en) 2020-11-25
IL237070B (en) 2019-06-30
KR20150039848A (ko) 2015-04-13
ZA201500466B (en) 2016-06-29
ES2800026T3 (es) 2020-12-23
CN115068484A (zh) 2022-09-20
CA2881113C (en) 2020-10-27
SG11201500983RA (en) 2015-04-29
EA029085B1 (ru) 2018-02-28
NZ628077A (en) 2017-04-28
SI2882441T1 (sl) 2020-08-31
AU2013299625A1 (en) 2015-02-12
CY1123106T1 (el) 2021-10-29
KR102266509B1 (ko) 2021-06-16
CN114939119A (zh) 2022-08-26
JP6595565B2 (ja) 2019-10-23
JP6250671B2 (ja) 2017-12-20
TW201408298A (zh) 2014-03-01
AU2013299625B2 (en) 2018-02-01
US20210340132A1 (en) 2021-11-04
JP2015527349A (ja) 2015-09-17
KR102118559B1 (ko) 2020-06-03
EP2882441A2 (en) 2015-06-17
CA2881113A1 (en) 2014-02-13
LT2882441T (lt) 2020-07-27

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