HK1208496A1 - Cell culture compositions and methods for polypeptide production - Google Patents
Cell culture compositions and methods for polypeptide productionInfo
- Publication number
- HK1208496A1 HK1208496A1 HK15109118.1A HK15109118A HK1208496A1 HK 1208496 A1 HK1208496 A1 HK 1208496A1 HK 15109118 A HK15109118 A HK 15109118A HK 1208496 A1 HK1208496 A1 HK 1208496A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- methods
- cell culture
- polypeptide production
- culture compositions
- compositions
- Prior art date
Links
- 238000004113 cell culture Methods 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
- 229920001184 polypeptide Polymers 0.000 title 1
- 102000004196 processed proteins & peptides Human genes 0.000 title 1
- 108090000765 processed proteins & peptides Proteins 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/0018—Culture media for cell or tissue culture
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/0018—Culture media for cell or tissue culture
- C12N5/005—Protein-free medium
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/05—Inorganic components
- C12N2500/10—Metals; Metal chelators
- C12N2500/20—Transition metals
- C12N2500/24—Iron; Fe chelators; Transferrin
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/30—Organic components
- C12N2500/32—Amino acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/30—Organic components
- C12N2500/38—Vitamins
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/30—Hormones
- C12N2501/38—Hormones with nuclear receptors
- C12N2501/39—Steroid hormones
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Molecular Biology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicinal Chemistry (AREA)
- Biophysics (AREA)
- Immunology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201261637780P | 2012-04-24 | 2012-04-24 | |
US201261637778P | 2012-04-24 | 2012-04-24 | |
US13/841,864 US20130281355A1 (en) | 2012-04-24 | 2013-03-15 | Cell culture compositions and methods for polypeptide production |
PCT/US2013/037992 WO2013163294A1 (en) | 2012-04-24 | 2013-04-24 | Cell culture compositions and methods for polypeptide production |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1208496A1 true HK1208496A1 (en) | 2016-03-04 |
Family
ID=49380652
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK15109118.1A HK1208496A1 (en) | 2012-04-24 | 2015-09-17 | Cell culture compositions and methods for polypeptide production |
Country Status (22)
Country | Link |
---|---|
US (2) | US20130281355A1 (ru) |
EP (2) | EP2841561B1 (ru) |
JP (4) | JP6367792B2 (ru) |
KR (2) | KR102115052B1 (ru) |
CN (2) | CN111440758A (ru) |
AR (1) | AR090822A1 (ru) |
AU (2) | AU2013251647B2 (ru) |
BR (1) | BR112014026308A8 (ru) |
CA (1) | CA2871006C (ru) |
ES (1) | ES2716301T3 (ru) |
HK (1) | HK1208496A1 (ru) |
HR (1) | HRP20190484T1 (ru) |
IL (1) | IL235235A0 (ru) |
MX (2) | MX363493B (ru) |
MY (1) | MY181513A (ru) |
NZ (1) | NZ701791A (ru) |
PL (1) | PL2841561T3 (ru) |
RU (2) | RU2678142C2 (ru) |
SG (2) | SG11201406903SA (ru) |
SI (1) | SI2841561T1 (ru) |
WO (1) | WO2013163294A1 (ru) |
ZA (2) | ZA201408092B (ru) |
Families Citing this family (20)
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US9334319B2 (en) | 2012-04-20 | 2016-05-10 | Abbvie Inc. | Low acidic species compositions |
WO2013158273A1 (en) | 2012-04-20 | 2013-10-24 | Abbvie Inc. | Methods to modulate c-terminal lysine variant distribution |
WO2014145091A1 (en) * | 2013-03-15 | 2014-09-18 | Genentech, Inc. | Cell culture media and methods of antibody production |
CA2903596C (en) * | 2013-03-15 | 2023-10-03 | Genentech, Inc. | Cell culture compositions with antioxidants and methods for polypeptide production |
EP3052640A2 (en) * | 2013-10-04 | 2016-08-10 | AbbVie Inc. | Use of metal ions for modulation of protein glycosylation profiles of recombinant proteins |
GB201708655D0 (en) | 2017-05-31 | 2017-07-12 | Ucb Biopharma Sprl | Cell culture methods |
CN110945593A (zh) * | 2017-06-16 | 2020-03-31 | 通用电气健康护理生物科学股份公司 | 用于预测生物反应器中的过程的产出和对生物反应器中的过程建模的方法 |
EP3492582A1 (en) | 2017-12-01 | 2019-06-05 | UCB Biopharma SPRL | Cell culture methods |
CN108823267B (zh) * | 2018-06-25 | 2020-05-08 | 深圳市菲鹏生物制药股份有限公司 | 调节cho-k1表达系统所分泌抗体的酸性峰含量的方法 |
US20220411795A1 (en) * | 2019-10-31 | 2022-12-29 | William Marsh Rice University | Engineered cells for controlled production |
JP2022550930A (ja) * | 2019-12-06 | 2022-12-06 | リジェネロン・ファーマシューティカルズ・インコーポレイテッド | 抗vegfタンパク質組成物及びその製造方法 |
BR112022012467A2 (pt) * | 2020-01-31 | 2022-09-06 | Chugai Pharmaceutical Co Ltd | Método para produção de composição contendo polipeptídeo com coloração suprimida |
JP7404930B2 (ja) | 2020-02-26 | 2023-12-26 | 富士フイルムビジネスイノベーション株式会社 | 発光装置、光学装置及び計測装置 |
JP7404929B2 (ja) | 2020-02-26 | 2023-12-26 | 富士フイルムビジネスイノベーション株式会社 | 発光装置、光学装置及び計測装置 |
AU2021268026A1 (en) | 2020-05-08 | 2023-01-19 | Regeneron Pharmaceuticals, Inc. | VEGF traps and mini-traps and methods for treating ocular disorders and cancer |
GB202012991D0 (en) | 2020-08-20 | 2020-10-07 | Ucb Biopharma Sprl | Cell culture processes |
IL303951A (en) * | 2020-12-22 | 2023-08-01 | Novartis Ag | Methods for reducing the oxidation level of cysteine residues in recombinantly secreted protein during cell culture |
GB202105424D0 (en) | 2021-04-16 | 2021-06-02 | UCB Biopharma SRL | Cell culture processes |
WO2023031409A1 (en) | 2021-09-02 | 2023-03-09 | Boehringer Ingelheim International Gmbh | Method of determining a future color value or corresponding property and arrangement therefor |
KR102682066B1 (ko) * | 2021-10-12 | 2024-07-05 | 프레스티지바이오로직스 주식회사 | 항체 집단의 제조 방법 |
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RU2011116319A (ru) * | 2008-09-26 | 2012-11-10 | Шеринг Корпорейшн (US) | Производство высокого титра антител |
JO3672B1 (ar) * | 2008-12-15 | 2020-08-27 | Regeneron Pharma | أجسام مضادة بشرية عالية التفاعل الكيماوي بالنسبة لإنزيم سبتيليسين كنفرتيز بروبروتين / كيكسين نوع 9 (pcsk9). |
US9540426B2 (en) * | 2009-10-06 | 2017-01-10 | Bristol-Myers Squibb Company | Mammalian cell culture processes for protein production |
SG185038A1 (en) | 2010-04-26 | 2012-11-29 | Novartis Ag | Improved cell culture medium |
-
2013
- 2013-03-15 US US13/841,864 patent/US20130281355A1/en not_active Abandoned
- 2013-04-24 KR KR1020147032389A patent/KR102115052B1/ko active IP Right Grant
- 2013-04-24 SI SI201331376T patent/SI2841561T1/sl unknown
- 2013-04-24 MX MX2014012838A patent/MX363493B/es unknown
- 2013-04-24 CN CN202010250367.4A patent/CN111440758A/zh active Pending
- 2013-04-24 BR BR112014026308A patent/BR112014026308A8/pt not_active Application Discontinuation
- 2013-04-24 CA CA2871006A patent/CA2871006C/en active Active
- 2013-04-24 SG SG11201406903SA patent/SG11201406903SA/en unknown
- 2013-04-24 AR ARP130101367 patent/AR090822A1/es unknown
- 2013-04-24 MY MYPI2014003007A patent/MY181513A/en unknown
- 2013-04-24 CN CN201380032959.7A patent/CN104428409A/zh active Pending
- 2013-04-24 WO PCT/US2013/037992 patent/WO2013163294A1/en active Application Filing
- 2013-04-24 SG SG10201810830UA patent/SG10201810830UA/en unknown
- 2013-04-24 NZ NZ701791A patent/NZ701791A/en unknown
- 2013-04-24 AU AU2013251647A patent/AU2013251647B2/en active Active
- 2013-04-24 JP JP2015509107A patent/JP6367792B2/ja active Active
- 2013-04-24 EP EP13720203.2A patent/EP2841561B1/en not_active Revoked
- 2013-04-24 PL PL13720203T patent/PL2841561T3/pl unknown
- 2013-04-24 EP EP18213796.8A patent/EP3533864A1/en active Pending
- 2013-04-24 KR KR1020207014171A patent/KR102339106B1/ko active IP Right Grant
- 2013-04-24 ES ES13720203T patent/ES2716301T3/es active Active
- 2013-04-24 RU RU2014147018A patent/RU2678142C2/ru active
- 2013-04-24 RU RU2018146497A patent/RU2018146497A/ru unknown
-
2014
- 2014-10-21 IL IL235235A patent/IL235235A0/en unknown
- 2014-10-23 MX MX2019003427A patent/MX2019003427A/es unknown
- 2014-11-05 ZA ZA2014/08092A patent/ZA201408092B/en unknown
-
2015
- 2015-09-17 HK HK15109118.1A patent/HK1208496A1/xx unknown
-
2017
- 2017-11-03 ZA ZA2017/07452A patent/ZA201707452B/en unknown
-
2018
- 2018-07-05 JP JP2018128429A patent/JP7323272B2/ja active Active
-
2019
- 2019-03-11 HR HRP20190484TT patent/HRP20190484T1/hr unknown
- 2019-04-02 AU AU2019202259A patent/AU2019202259B2/en active Active
-
2021
- 2021-03-16 JP JP2021042702A patent/JP2021104023A/ja not_active Withdrawn
-
2023
- 2023-07-28 JP JP2023123219A patent/JP2023156371A/ja active Pending
- 2023-10-30 US US18/497,162 patent/US20240093143A1/en not_active Abandoned
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