ATE222598T1 - Menschliche immortalisierte colon- epithelialzellen - Google Patents

Menschliche immortalisierte colon- epithelialzellen

Info

Publication number
ATE222598T1
ATE222598T1 AT96201064T AT96201064T ATE222598T1 AT E222598 T1 ATE222598 T1 AT E222598T1 AT 96201064 T AT96201064 T AT 96201064T AT 96201064 T AT96201064 T AT 96201064T AT E222598 T1 ATE222598 T1 AT E222598T1
Authority
AT
Austria
Prior art keywords
epithelial cells
colon epithelial
cells
human colon
immortalising
Prior art date
Application number
AT96201064T
Other languages
English (en)
Inventor
Stephanie Blum
Andrea Pfeifer
Yvonne Troumvoukis
Original Assignee
Nestle Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nestle Sa filed Critical Nestle Sa
Application granted granted Critical
Publication of ATE222598T1 publication Critical patent/ATE222598T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0679Cells of the gastro-intestinal tract
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00Specific components of cell culture medium
    • C12N2500/05Inorganic components
    • C12N2500/10Metals; Metal chelators
    • C12N2500/20Transition metals
    • C12N2500/24Iron; Fe chelators; Transferrin
    • C12N2500/25Insulin-transferrin; Insulin-transferrin-selenium
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00Specific components of cell culture medium
    • C12N2500/30Organic components
    • C12N2500/38Vitamins
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00Specific components of cell culture medium
    • C12N2500/90Serum-free medium, which may still contain naturally-sourced components
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10Growth factors
    • C12N2501/11Epidermal growth factor [EGF]
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/30Hormones
    • C12N2501/38Hormones with nuclear receptors
    • C12N2501/39Steroid hormones
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/30Hormones
    • C12N2501/38Hormones with nuclear receptors
    • C12N2501/395Thyroid hormones
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2503/00Use of cells in diagnostics
    • C12N2503/02Drug screening
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2510/00Genetically modified cells
    • C12N2510/04Immortalised cells

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Prostheses (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
AT96201064T 1996-04-19 1996-04-19 Menschliche immortalisierte colon- epithelialzellen ATE222598T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP96201064A EP0802257B1 (de) 1996-04-19 1996-04-19 Menschliche immortalisierte Colon-Epithelialzellen

Publications (1)

Publication Number Publication Date
ATE222598T1 true ATE222598T1 (de) 2002-09-15

Family

ID=8223895

Family Applications (1)

Application Number Title Priority Date Filing Date
AT96201064T ATE222598T1 (de) 1996-04-19 1996-04-19 Menschliche immortalisierte colon- epithelialzellen

Country Status (14)

Country Link
US (3) US6194203B1 (de)
EP (1) EP0802257B1 (de)
JP (1) JP3931212B2 (de)
AT (1) ATE222598T1 (de)
AU (1) AU733913B2 (de)
CA (1) CA2202923C (de)
DE (1) DE69623109T2 (de)
DK (1) DK0802257T3 (de)
ES (1) ES2180689T3 (de)
FI (1) FI120352B (de)
NO (1) NO319494B1 (de)
NZ (1) NZ314614A (de)
PT (1) PT802257E (de)
RU (1) RU2220201C2 (de)

Families Citing this family (47)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE222598T1 (de) * 1996-04-19 2002-09-15 Nestle Sa Menschliche immortalisierte colon- epithelialzellen
ES2277338T3 (es) 1996-12-24 2007-07-01 Societe Des Produits Nestle S.A. Linea inmortalizada de celulas epiteliales humanas de la cornea.
US5960073A (en) * 1997-04-03 1999-09-28 Genesys Telecommunications Laboratories , Inc. Method and apparatus for providing an interactive home agent with access to call center functionality and resources
DE19755023C2 (de) * 1997-12-11 2000-03-09 Celanese Chem Europe Gmbh Katalysator und Verfahren zur Herstellung von Vinylacetat
EP1048724A1 (de) * 1999-04-27 2000-11-02 Transgene S.A. Humane Myoblastzellinien und deren Anwendungen
EP1048725B1 (de) * 1999-04-27 2005-07-06 Transgene S.A. Verfahren zur Herstellung von Säugetier-Zellinien
US7078232B2 (en) * 1999-08-19 2006-07-18 Artecel, Inc. Adipose tissue-derived adult stem or stromal cells for the repair of articular cartilage fractures and uses thereof
US6429013B1 (en) * 1999-08-19 2002-08-06 Artecel Science, Inc. Use of adipose tissue-derived stromal cells for chondrocyte differentiation and cartilage repair
US6416999B1 (en) * 2000-04-07 2002-07-09 Raven Biotechnologies, Inc. Human Müllerian duct-derived epithelial cells and methods of isolation and uses thereof
WO2002066603A2 (en) * 2001-02-15 2002-08-29 Centocor, Inc. Chemically defined medium for cultured mammalian cells
WO2003104439A2 (en) * 2002-03-12 2003-12-18 Surface Logix, Inc. Assay device that analyzes the absorption, metabolism, permeability and/or toxicity of a candidate compound
US7115563B2 (en) * 2002-05-29 2006-10-03 Insignion Holding Limited Composition and its therapeutic use
GB0212405D0 (en) * 2002-05-29 2002-07-10 Insignion Holdings Ltd Composition and its therapeutic use
ES2333889T3 (es) * 2004-07-19 2010-03-02 Institut De Recherche Pour Le Developpement (Ird) Composiciones farmaceuticas para el tratamiento de la leishmaniasis.
US8273553B2 (en) * 2004-11-02 2012-09-25 Ares Trading S.A. Production of growth hormone in serum-free cell culture medium for mammalian cells
KR101196103B1 (ko) 2004-11-02 2012-11-01 아레스 트레이딩 에스.에이. 포유동물 세포용 무?혈청 세포 배양 배지
SG155183A1 (en) 2005-08-26 2009-09-30 Ares Trading Sa Process for the preparation of glycosylated interferon beta
US8911964B2 (en) 2006-09-13 2014-12-16 Abbvie Inc. Fed-batch method of making human anti-TNF-alpha antibody
BRPI0716762A2 (pt) 2006-09-13 2013-09-24 Abbott Lab melhorias da cultura celular
TW201028433A (en) 2008-10-20 2010-08-01 Abbott Lab Viral inactivation during purification of antibodies
TWI610936B (zh) * 2008-10-20 2018-01-11 艾伯維有限公司 使用蛋白質a親和性層析進行抗體之分離及純化
EP2702077A2 (de) 2011-04-27 2014-03-05 AbbVie Inc. Verfahren zur steuerung des galactosylierungsprofil von rekombinant exprimierten proteinen
AU2012283667B2 (en) * 2011-07-12 2015-07-09 Foodchek Systems, Inc. Culture medium, method for culturing Salmonella and E. coli and method for detecting Salmonella and E. coli
US9505833B2 (en) 2012-04-20 2016-11-29 Abbvie Inc. Human antibodies that bind human TNF-alpha and methods of preparing the same
US9181572B2 (en) 2012-04-20 2015-11-10 Abbvie, Inc. Methods to modulate lysine variant distribution
US9334319B2 (en) 2012-04-20 2016-05-10 Abbvie Inc. Low acidic species compositions
US9067990B2 (en) 2013-03-14 2015-06-30 Abbvie, Inc. Protein purification using displacement chromatography
US20130281355A1 (en) * 2012-04-24 2013-10-24 Genentech, Inc. Cell culture compositions and methods for polypeptide production
WO2013176754A1 (en) 2012-05-24 2013-11-28 Abbvie Inc. Novel purification of antibodies using hydrophobic interaction chromatography
US9512214B2 (en) 2012-09-02 2016-12-06 Abbvie, Inc. Methods to control protein heterogeneity
HK1211981A1 (en) 2012-09-02 2016-06-03 Abbvie Inc. Methods to control protein heterogeneity
EP2767273A1 (de) 2013-02-15 2014-08-20 Universitätsklinikum Erlangen Todassoziierte Proteinkinasen, Hemmer und Aktivatoren für die Verwendung in pharmazeutischen Zusammensetzungen und vorhersagbare Medizin
WO2014151878A2 (en) 2013-03-14 2014-09-25 Abbvie Inc. Methods for modulating protein glycosylation profiles of recombinant protein therapeutics using monosaccharides and oligosacharides
WO2014159579A1 (en) 2013-03-14 2014-10-02 Abbvie Inc. MUTATED ANTI-TNFα ANTIBODIES AND METHODS OF THEIR USE
US9017687B1 (en) 2013-10-18 2015-04-28 Abbvie, Inc. Low acidic species compositions and methods for producing and using the same using displacement chromatography
WO2015051293A2 (en) 2013-10-04 2015-04-09 Abbvie, Inc. Use of metal ions for modulation of protein glycosylation profiles of recombinant proteins
US9181337B2 (en) 2013-10-18 2015-11-10 Abbvie, Inc. Modulated lysine variant species compositions and methods for producing and using the same
US9085618B2 (en) 2013-10-18 2015-07-21 Abbvie, Inc. Low acidic species compositions and methods for producing and using the same
US8946395B1 (en) 2013-10-18 2015-02-03 Abbvie Inc. Purification of proteins using hydrophobic interaction chromatography
US20150139988A1 (en) 2013-11-15 2015-05-21 Abbvie, Inc. Glycoengineered binding protein compositions
EP3352586A4 (de) * 2015-09-21 2019-05-15 The Board Of Trustees Of The Leland Stanford Junior University Ernährungsbehandlung bei krebserkrankungen
CN110770337B (zh) * 2017-08-09 2023-11-21 株式会社漫丹 永生化汗腺肌上皮细胞
WO2019118519A1 (en) 2017-12-11 2019-06-20 Filtricine, Inc. Compositions, methods, kits and systems for cancer treatment and metabolic intervention therapy
CN111172114B (zh) * 2019-12-10 2021-11-30 上海中医药大学附属岳阳中西医结合医院 一种人源化肠癌前病变永生化上皮细胞系、构建方法及其应用
JP2023146683A (ja) * 2022-03-29 2023-10-12 株式会社ヤクルト本社 マウス由来大腸上皮細胞株
CN114891722A (zh) * 2022-05-13 2022-08-12 广东省农业科学院动物卫生研究所 禽肠道上皮细胞及其制备方法和应用
CN116083342A (zh) * 2023-01-16 2023-05-09 细新(上海)医疗科技有限公司 一种原代上皮细胞的培养体系和应用

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4229531A (en) * 1978-12-29 1980-10-21 Monsanto Company Production of tumor angiogenesis factor by cell culture
DE3711699A1 (de) * 1987-04-07 1988-11-10 Fraunhofer Ges Forschung Medium zur kultivierung und proliferation von epithelialen zelltypen
US4885238A (en) * 1987-10-30 1989-12-05 The United States Of America As Represented By The Department Of Health And Human Services Immortalized human bronchial epitherial mesothelial cell lines
WO1989005862A1 (en) * 1987-12-09 1989-06-29 Invitron Corporation Human cell life extension
US5093259A (en) * 1988-07-07 1992-03-03 Oak Ridge Associated Universities, Inc. Continuous cell-line tamarin adenocarcinoma of the colon
US5665589A (en) * 1988-12-14 1997-09-09 The United States Of America As Represented By The Department Of Health And Human Services Human liver epithelial cell lines
US5529920A (en) * 1988-12-14 1996-06-25 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Human liver epithelial cell line and culture media therefor
US5376542A (en) 1992-04-27 1994-12-27 Georgetown University Method for producing immortalized cell lines using human papilluma virus genes
DE69219768T2 (de) 1992-07-06 1997-08-28 Societe Des Produits Nestle S.A., Vevey Milchbakterien
US5462870A (en) * 1993-04-23 1995-10-31 Wayne State University Human diploid salivary gland epithelial cell lines
US5672498A (en) * 1993-12-28 1997-09-30 The Gillete Company Human corneal epithelial cell lines with extended lifespan
US5610043A (en) * 1994-04-28 1997-03-11 The United States Of America As Represented By The Department Of Health And Human Services Human prostatic cell lines immortalized by adenovirus 12-simian virus 40 (AD12/SV40) hybrid virus
ATE222598T1 (de) * 1996-04-19 2002-09-15 Nestle Sa Menschliche immortalisierte colon- epithelialzellen

Also Published As

Publication number Publication date
PT802257E (pt) 2003-01-31
US6194203B1 (en) 2001-02-27
NO971757L (no) 1997-10-20
CA2202923A1 (en) 1997-10-19
EP0802257B1 (de) 2002-08-21
AU733913B2 (en) 2001-05-31
RU2220201C2 (ru) 2003-12-27
FI971628A7 (fi) 1997-10-20
DK0802257T3 (da) 2002-10-28
DE69623109T2 (de) 2002-12-12
US6395542B1 (en) 2002-05-28
ES2180689T3 (es) 2003-02-16
NZ314614A (en) 1999-04-29
FI120352B (fi) 2009-09-30
NO971757D0 (no) 1997-04-17
CA2202923C (en) 2008-06-10
EP0802257A1 (de) 1997-10-22
US6399381B1 (en) 2002-06-04
JPH1028580A (ja) 1998-02-03
DE69623109D1 (de) 2002-09-26
JP3931212B2 (ja) 2007-06-13
AU1893397A (en) 1997-10-23
FI971628A0 (fi) 1997-04-17
NO319494B1 (no) 2005-08-22

Similar Documents

Publication Publication Date Title
ATE222598T1 (de) Menschliche immortalisierte colon- epithelialzellen
Peehl et al. Growth and differentiation of human keratinocytes without a feeder layer or conditioned medium
Tong et al. Long-term culture of rat liver cell spheroids in hormonally defined media
US5712163A (en) Chemically defined cell culture media and system and methods for use, particularly for culturing epithelial cells
US5342777A (en) Cell culture medium for human liver epithelial cell line
CN103857789B (zh) 制备间充质干细胞基础培养基和利用间充质干细胞基础培养基制备细胞治疗产品的方法及用该培养基得到的分化产品
Brandi et al. Bovine parathyroid cells: cultures maintained for more than 140 population doublings.
WO1998059035A3 (en) Serum-free cell growth medium
EP0501435B1 (de) Serumfreies Medium zur Züchtung von Tierzellen
CN108949678B (zh) 一种干细胞培养基及培养方法
US11485955B2 (en) Formula of serum-free medium for human pluripotent stem cells
Gilchrest et al. Autocrine and paracrine growth stimulation of cells derived from human skin
TW200927927A (en) Stem cell medium
CN111440764A (zh) 间充质干细胞的无血清培养基及间充质干细胞的临床级规模化培养方法
CN101984051A (zh) 适合肿瘤干细胞富集与培养的无血清细胞培养液
Kaighn et al. Growth control of prostatic carcinoma cells in serum-free media: interrelationship of hormone response, cell density, and nutrient media.
Ham Dermal fibroblasts
Webber et al. Serum‐free culture of rabbit meniscal fibrochondrocytes: Proliferative response
CN100506977C (zh) 一种中国仓鼠卵巢细胞扩增培养基及其用途
Wu et al. Replacement of serum in cell culture by hormones: A study of hormonal regulation of cell growth and specific gene expression
Gasser et al. Long-term multiplication of the Chinese hamster ovary (CHO) cell line in a serum-free medium
CN117625519B (zh) 促肌肉干细胞体外存活和增殖的无胎牛血清培养基及其应用
Rikimaru et al. Growth of the malignant and nonmalignant human squamous cells in a protein-free defined medium
CN106801030A (zh) 适于肝样细胞体外培养的替代血清组合物及其使用方法
Roberts et al. A novel epithelial cell from neonatal rat lung: isolation and differentiated phenotype

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification