ATE222598T1 - Menschliche immortalisierte colon- epithelialzellen - Google Patents
Menschliche immortalisierte colon- epithelialzellenInfo
- Publication number
- ATE222598T1 ATE222598T1 AT96201064T AT96201064T ATE222598T1 AT E222598 T1 ATE222598 T1 AT E222598T1 AT 96201064 T AT96201064 T AT 96201064T AT 96201064 T AT96201064 T AT 96201064T AT E222598 T1 ATE222598 T1 AT E222598T1
- Authority
- AT
- Austria
- Prior art keywords
- epithelial cells
- colon epithelial
- cells
- human colon
- immortalising
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0679—Cells of the gastro-intestinal tract
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/05—Inorganic components
- C12N2500/10—Metals; Metal chelators
- C12N2500/20—Transition metals
- C12N2500/24—Iron; Fe chelators; Transferrin
- C12N2500/25—Insulin-transferrin; Insulin-transferrin-selenium
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/30—Organic components
- C12N2500/38—Vitamins
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/90—Serum-free medium, which may still contain naturally-sourced components
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/11—Epidermal growth factor [EGF]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/30—Hormones
- C12N2501/38—Hormones with nuclear receptors
- C12N2501/39—Steroid hormones
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/30—Hormones
- C12N2501/38—Hormones with nuclear receptors
- C12N2501/395—Thyroid hormones
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2503/00—Use of cells in diagnostics
- C12N2503/02—Drug screening
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2510/00—Genetically modified cells
- C12N2510/04—Immortalised cells
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP96201064A EP0802257B1 (de) | 1996-04-19 | 1996-04-19 | Menschliche immortalisierte Colon-Epithelialzellen |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE222598T1 true ATE222598T1 (de) | 2002-09-15 |
Family
ID=8223895
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT96201064T ATE222598T1 (de) | 1996-04-19 | 1996-04-19 | Menschliche immortalisierte colon- epithelialzellen |
Country Status (14)
Country | Link |
---|---|
US (3) | US6194203B1 (de) |
EP (1) | EP0802257B1 (de) |
JP (1) | JP3931212B2 (de) |
AT (1) | ATE222598T1 (de) |
AU (1) | AU733913B2 (de) |
CA (1) | CA2202923C (de) |
DE (1) | DE69623109T2 (de) |
DK (1) | DK0802257T3 (de) |
ES (1) | ES2180689T3 (de) |
FI (1) | FI120352B (de) |
NO (1) | NO319494B1 (de) |
NZ (1) | NZ314614A (de) |
PT (1) | PT802257E (de) |
RU (1) | RU2220201C2 (de) |
Families Citing this family (46)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
PT802257E (pt) * | 1996-04-19 | 2003-01-31 | Nestle Sa | Linhagem imortalizada de celulas epiteliais do colon humano |
DE69636755T2 (de) | 1996-12-24 | 2007-10-11 | Société des Produits Nestlé S.A. | Immortalisierte menschliche Epithelzell-Linie |
US5960073A (en) * | 1997-04-03 | 1999-09-28 | Genesys Telecommunications Laboratories , Inc. | Method and apparatus for providing an interactive home agent with access to call center functionality and resources |
DE19755023C2 (de) * | 1997-12-11 | 2000-03-09 | Celanese Chem Europe Gmbh | Katalysator und Verfahren zur Herstellung von Vinylacetat |
DE69926053T2 (de) * | 1999-04-27 | 2006-04-27 | Transgene S.A. | Verfahren zur Herstellung von Säugetier-Zellinien |
EP1048724A1 (de) * | 1999-04-27 | 2000-11-02 | Transgene S.A. | Humane Myoblastzellinien und deren Anwendungen |
US6429013B1 (en) * | 1999-08-19 | 2002-08-06 | Artecel Science, Inc. | Use of adipose tissue-derived stromal cells for chondrocyte differentiation and cartilage repair |
US7078232B2 (en) | 1999-08-19 | 2006-07-18 | Artecel, Inc. | Adipose tissue-derived adult stem or stromal cells for the repair of articular cartilage fractures and uses thereof |
US6416999B1 (en) * | 2000-04-07 | 2002-07-09 | Raven Biotechnologies, Inc. | Human Müllerian duct-derived epithelial cells and methods of isolation and uses thereof |
ATE420945T1 (de) * | 2001-02-15 | 2009-01-15 | Centocor Inc | Chemisch definiertes medium für kultivierte säugerzellen |
WO2003104439A2 (en) * | 2002-03-12 | 2003-12-18 | Surface Logix, Inc. | Assay device that analyzes the absorption, metabolism, permeability and/or toxicity of a candidate compound |
GB0212405D0 (en) * | 2002-05-29 | 2002-07-10 | Insignion Holdings Ltd | Composition and its therapeutic use |
US7115563B2 (en) * | 2002-05-29 | 2006-10-03 | Insignion Holding Limited | Composition and its therapeutic use |
ES2333889T3 (es) * | 2004-07-19 | 2010-03-02 | Institut De Recherche Pour Le Developpement (Ird) | Composiciones farmaceuticas para el tratamiento de la leishmaniasis. |
US8273553B2 (en) * | 2004-11-02 | 2012-09-25 | Ares Trading S.A. | Production of growth hormone in serum-free cell culture medium for mammalian cells |
SI1807504T1 (sl) | 2004-11-02 | 2011-05-31 | Ares Trading Sa | Brezserumski celiäśni kultivacijski medij za celice sesalcev |
RS57549B1 (sr) | 2005-08-26 | 2018-10-31 | Ares Trading Sa | Proces za pripremu glikoziliranog interferona beta |
TWI548747B (zh) | 2006-09-13 | 2016-09-11 | 艾伯維有限公司 | 細胞培養改良 |
US8911964B2 (en) | 2006-09-13 | 2014-12-16 | Abbvie Inc. | Fed-batch method of making human anti-TNF-alpha antibody |
ES2535734T3 (es) | 2008-10-20 | 2015-05-14 | Abbvie Inc. | Aislamiento y purificación de anticuerpos mediante cromatografía de afinidad con la proteína A |
TW201028433A (en) | 2008-10-20 | 2010-08-01 | Abbott Lab | Viral inactivation during purification of antibodies |
WO2012149197A2 (en) | 2011-04-27 | 2012-11-01 | Abbott Laboratories | Methods for controlling the galactosylation profile of recombinantly-expressed proteins |
EP2732027B1 (de) * | 2011-07-12 | 2017-03-01 | Foodchek Systems, Inc. | Kulturmedium, verfahren zur kultivierung von salmonella und e. coli sowie verfahren zur erkennung von salmonella und e. coli |
US9067990B2 (en) | 2013-03-14 | 2015-06-30 | Abbvie, Inc. | Protein purification using displacement chromatography |
WO2013158273A1 (en) | 2012-04-20 | 2013-10-24 | Abbvie Inc. | Methods to modulate c-terminal lysine variant distribution |
WO2013158279A1 (en) | 2012-04-20 | 2013-10-24 | Abbvie Inc. | Protein purification methods to reduce acidic species |
US9505833B2 (en) | 2012-04-20 | 2016-11-29 | Abbvie Inc. | Human antibodies that bind human TNF-alpha and methods of preparing the same |
US20130281355A1 (en) * | 2012-04-24 | 2013-10-24 | Genentech, Inc. | Cell culture compositions and methods for polypeptide production |
US9249182B2 (en) | 2012-05-24 | 2016-02-02 | Abbvie, Inc. | Purification of antibodies using hydrophobic interaction chromatography |
US9206390B2 (en) | 2012-09-02 | 2015-12-08 | Abbvie, Inc. | Methods to control protein heterogeneity |
US9512214B2 (en) | 2012-09-02 | 2016-12-06 | Abbvie, Inc. | Methods to control protein heterogeneity |
EP2767273A1 (de) | 2013-02-15 | 2014-08-20 | Universitätsklinikum Erlangen | Todassoziierte Proteinkinasen, Hemmer und Aktivatoren für die Verwendung in pharmazeutischen Zusammensetzungen und vorhersagbare Medizin |
US9499614B2 (en) | 2013-03-14 | 2016-11-22 | Abbvie Inc. | Methods for modulating protein glycosylation profiles of recombinant protein therapeutics using monosaccharides and oligosaccharides |
WO2014159579A1 (en) | 2013-03-14 | 2014-10-02 | Abbvie Inc. | MUTATED ANTI-TNFα ANTIBODIES AND METHODS OF THEIR USE |
US9017687B1 (en) | 2013-10-18 | 2015-04-28 | Abbvie, Inc. | Low acidic species compositions and methods for producing and using the same using displacement chromatography |
WO2015051293A2 (en) | 2013-10-04 | 2015-04-09 | Abbvie, Inc. | Use of metal ions for modulation of protein glycosylation profiles of recombinant proteins |
US9085618B2 (en) | 2013-10-18 | 2015-07-21 | Abbvie, Inc. | Low acidic species compositions and methods for producing and using the same |
US9181337B2 (en) | 2013-10-18 | 2015-11-10 | Abbvie, Inc. | Modulated lysine variant species compositions and methods for producing and using the same |
US8946395B1 (en) | 2013-10-18 | 2015-02-03 | Abbvie Inc. | Purification of proteins using hydrophobic interaction chromatography |
WO2015073884A2 (en) | 2013-11-15 | 2015-05-21 | Abbvie, Inc. | Glycoengineered binding protein compositions |
CA3033333A1 (en) | 2015-09-21 | 2017-03-30 | The Board Of Trustees Of The Leland Stanford Junior University | Nutritional treatment for cancer |
KR102334203B1 (ko) * | 2017-08-09 | 2021-12-02 | 가부시키가이샤 만다무 | 불사화(不死化) 땀샘 근상피 세포 |
WO2019118519A1 (en) | 2017-12-11 | 2019-06-20 | Filtricine, Inc. | Compositions, methods, kits and systems for cancer treatment and metabolic intervention therapy |
CN111172114B (zh) * | 2019-12-10 | 2021-11-30 | 上海中医药大学附属岳阳中西医结合医院 | 一种人源化肠癌前病变永生化上皮细胞系、构建方法及其应用 |
CN114891722A (zh) * | 2022-05-13 | 2022-08-12 | 广东省农业科学院动物卫生研究所 | 禽肠道上皮细胞及其制备方法和应用 |
CN116083342A (zh) * | 2023-01-16 | 2023-05-09 | 细新(上海)医疗科技有限公司 | 一种原代上皮细胞的培养体系和应用 |
Family Cites Families (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4229531A (en) * | 1978-12-29 | 1980-10-21 | Monsanto Company | Production of tumor angiogenesis factor by cell culture |
DE3711699A1 (de) * | 1987-04-07 | 1988-11-10 | Fraunhofer Ges Forschung | Medium zur kultivierung und proliferation von epithelialen zelltypen |
US4885238A (en) * | 1987-10-30 | 1989-12-05 | The United States Of America As Represented By The Department Of Health And Human Services | Immortalized human bronchial epitherial mesothelial cell lines |
AU2921289A (en) * | 1987-12-09 | 1989-07-19 | Invitron Corporation | Human cell life extension |
US5093259A (en) * | 1988-07-07 | 1992-03-03 | Oak Ridge Associated Universities, Inc. | Continuous cell-line tamarin adenocarcinoma of the colon |
US5665589A (en) * | 1988-12-14 | 1997-09-09 | The United States Of America As Represented By The Department Of Health And Human Services | Human liver epithelial cell lines |
US5529920A (en) * | 1988-12-14 | 1996-06-25 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Human liver epithelial cell line and culture media therefor |
US5376542A (en) | 1992-04-27 | 1994-12-27 | Georgetown University | Method for producing immortalized cell lines using human papilluma virus genes |
ATE172245T1 (de) | 1992-07-06 | 1998-10-15 | Nestle Sa | Milchbakterien |
US5462870A (en) * | 1993-04-23 | 1995-10-31 | Wayne State University | Human diploid salivary gland epithelial cell lines |
US5672498A (en) * | 1993-12-28 | 1997-09-30 | The Gillete Company | Human corneal epithelial cell lines with extended lifespan |
US5610043A (en) * | 1994-04-28 | 1997-03-11 | The United States Of America As Represented By The Department Of Health And Human Services | Human prostatic cell lines immortalized by adenovirus 12-simian virus 40 (AD12/SV40) hybrid virus |
PT802257E (pt) * | 1996-04-19 | 2003-01-31 | Nestle Sa | Linhagem imortalizada de celulas epiteliais do colon humano |
-
1996
- 1996-04-19 PT PT96201064T patent/PT802257E/pt unknown
- 1996-04-19 DK DK96201064T patent/DK0802257T3/da active
- 1996-04-19 ES ES96201064T patent/ES2180689T3/es not_active Expired - Lifetime
- 1996-04-19 DE DE69623109T patent/DE69623109T2/de not_active Expired - Lifetime
- 1996-04-19 EP EP96201064A patent/EP0802257B1/de not_active Expired - Lifetime
- 1996-04-19 AT AT96201064T patent/ATE222598T1/de active
-
1997
- 1997-04-16 CA CA002202923A patent/CA2202923C/en not_active Expired - Fee Related
- 1997-04-16 NZ NZ314614A patent/NZ314614A/en not_active IP Right Cessation
- 1997-04-16 RU RU97106170/13A patent/RU2220201C2/ru not_active IP Right Cessation
- 1997-04-17 NO NO19971757A patent/NO319494B1/no not_active IP Right Cessation
- 1997-04-17 AU AU18933/97A patent/AU733913B2/en not_active Ceased
- 1997-04-17 FI FI971628A patent/FI120352B/fi not_active IP Right Cessation
- 1997-04-17 US US08/839,271 patent/US6194203B1/en not_active Expired - Lifetime
- 1997-04-18 JP JP10217297A patent/JP3931212B2/ja not_active Expired - Fee Related
-
2000
- 2000-06-14 US US09/593,134 patent/US6395542B1/en not_active Expired - Lifetime
- 2000-06-14 US US09/593,135 patent/US6399381B1/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
NO971757L (no) | 1997-10-20 |
DE69623109T2 (de) | 2002-12-12 |
JPH1028580A (ja) | 1998-02-03 |
AU1893397A (en) | 1997-10-23 |
FI120352B (fi) | 2009-09-30 |
NO319494B1 (no) | 2005-08-22 |
EP0802257B1 (de) | 2002-08-21 |
PT802257E (pt) | 2003-01-31 |
US6194203B1 (en) | 2001-02-27 |
FI971628A0 (fi) | 1997-04-17 |
DE69623109D1 (de) | 2002-09-26 |
ES2180689T3 (es) | 2003-02-16 |
NO971757D0 (no) | 1997-04-17 |
JP3931212B2 (ja) | 2007-06-13 |
NZ314614A (en) | 1999-04-29 |
US6399381B1 (en) | 2002-06-04 |
US6395542B1 (en) | 2002-05-28 |
RU2220201C2 (ru) | 2003-12-27 |
CA2202923A1 (en) | 1997-10-19 |
EP0802257A1 (de) | 1997-10-22 |
FI971628A (fi) | 1997-10-20 |
AU733913B2 (en) | 2001-05-31 |
DK0802257T3 (da) | 2002-10-28 |
CA2202923C (en) | 2008-06-10 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
UEP | Publication of translation of european patent specification |