ATE222598T1 - Menschliche immortalisierte colon- epithelialzellen - Google Patents

Menschliche immortalisierte colon- epithelialzellen

Info

Publication number
ATE222598T1
ATE222598T1 AT96201064T AT96201064T ATE222598T1 AT E222598 T1 ATE222598 T1 AT E222598T1 AT 96201064 T AT96201064 T AT 96201064T AT 96201064 T AT96201064 T AT 96201064T AT E222598 T1 ATE222598 T1 AT E222598T1
Authority
AT
Austria
Prior art keywords
epithelial cells
colon epithelial
cells
human colon
immortalising
Prior art date
Application number
AT96201064T
Other languages
English (en)
Inventor
Stephanie Blum
Andrea Pfeifer
Yvonne Troumvoukis
Original Assignee
Nestle Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nestle Sa filed Critical Nestle Sa
Application granted granted Critical
Publication of ATE222598T1 publication Critical patent/ATE222598T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0679Cells of the gastro-intestinal tract
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00Specific components of cell culture medium
    • C12N2500/05Inorganic components
    • C12N2500/10Metals; Metal chelators
    • C12N2500/20Transition metals
    • C12N2500/24Iron; Fe chelators; Transferrin
    • C12N2500/25Insulin-transferrin; Insulin-transferrin-selenium
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00Specific components of cell culture medium
    • C12N2500/30Organic components
    • C12N2500/38Vitamins
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00Specific components of cell culture medium
    • C12N2500/90Serum-free medium, which may still contain naturally-sourced components
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10Growth factors
    • C12N2501/11Epidermal growth factor [EGF]
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/30Hormones
    • C12N2501/38Hormones with nuclear receptors
    • C12N2501/39Steroid hormones
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/30Hormones
    • C12N2501/38Hormones with nuclear receptors
    • C12N2501/395Thyroid hormones
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2503/00Use of cells in diagnostics
    • C12N2503/02Drug screening
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2510/00Genetically modified cells
    • C12N2510/04Immortalised cells
AT96201064T 1996-04-19 1996-04-19 Menschliche immortalisierte colon- epithelialzellen ATE222598T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP96201064A EP0802257B1 (de) 1996-04-19 1996-04-19 Menschliche immortalisierte Colon-Epithelialzellen

Publications (1)

Publication Number Publication Date
ATE222598T1 true ATE222598T1 (de) 2002-09-15

Family

ID=8223895

Family Applications (1)

Application Number Title Priority Date Filing Date
AT96201064T ATE222598T1 (de) 1996-04-19 1996-04-19 Menschliche immortalisierte colon- epithelialzellen

Country Status (14)

Country Link
US (3) US6194203B1 (de)
EP (1) EP0802257B1 (de)
JP (1) JP3931212B2 (de)
AT (1) ATE222598T1 (de)
AU (1) AU733913B2 (de)
CA (1) CA2202923C (de)
DE (1) DE69623109T2 (de)
DK (1) DK0802257T3 (de)
ES (1) ES2180689T3 (de)
FI (1) FI120352B (de)
NO (1) NO319494B1 (de)
NZ (1) NZ314614A (de)
PT (1) PT802257E (de)
RU (1) RU2220201C2 (de)

Families Citing this family (46)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT802257E (pt) * 1996-04-19 2003-01-31 Nestle Sa Linhagem imortalizada de celulas epiteliais do colon humano
DE69636755T2 (de) 1996-12-24 2007-10-11 Société des Produits Nestlé S.A. Immortalisierte menschliche Epithelzell-Linie
US5960073A (en) * 1997-04-03 1999-09-28 Genesys Telecommunications Laboratories , Inc. Method and apparatus for providing an interactive home agent with access to call center functionality and resources
DE19755023C2 (de) * 1997-12-11 2000-03-09 Celanese Chem Europe Gmbh Katalysator und Verfahren zur Herstellung von Vinylacetat
DE69926053T2 (de) * 1999-04-27 2006-04-27 Transgene S.A. Verfahren zur Herstellung von Säugetier-Zellinien
EP1048724A1 (de) * 1999-04-27 2000-11-02 Transgene S.A. Humane Myoblastzellinien und deren Anwendungen
US6429013B1 (en) * 1999-08-19 2002-08-06 Artecel Science, Inc. Use of adipose tissue-derived stromal cells for chondrocyte differentiation and cartilage repair
US7078232B2 (en) 1999-08-19 2006-07-18 Artecel, Inc. Adipose tissue-derived adult stem or stromal cells for the repair of articular cartilage fractures and uses thereof
US6416999B1 (en) * 2000-04-07 2002-07-09 Raven Biotechnologies, Inc. Human Müllerian duct-derived epithelial cells and methods of isolation and uses thereof
ATE420945T1 (de) * 2001-02-15 2009-01-15 Centocor Inc Chemisch definiertes medium für kultivierte säugerzellen
WO2003104439A2 (en) * 2002-03-12 2003-12-18 Surface Logix, Inc. Assay device that analyzes the absorption, metabolism, permeability and/or toxicity of a candidate compound
GB0212405D0 (en) * 2002-05-29 2002-07-10 Insignion Holdings Ltd Composition and its therapeutic use
US7115563B2 (en) * 2002-05-29 2006-10-03 Insignion Holding Limited Composition and its therapeutic use
ES2333889T3 (es) * 2004-07-19 2010-03-02 Institut De Recherche Pour Le Developpement (Ird) Composiciones farmaceuticas para el tratamiento de la leishmaniasis.
US8273553B2 (en) * 2004-11-02 2012-09-25 Ares Trading S.A. Production of growth hormone in serum-free cell culture medium for mammalian cells
SI1807504T1 (sl) 2004-11-02 2011-05-31 Ares Trading Sa Brezserumski celiäśni kultivacijski medij za celice sesalcev
RS57549B1 (sr) 2005-08-26 2018-10-31 Ares Trading Sa Proces za pripremu glikoziliranog interferona beta
TWI548747B (zh) 2006-09-13 2016-09-11 艾伯維有限公司 細胞培養改良
US8911964B2 (en) 2006-09-13 2014-12-16 Abbvie Inc. Fed-batch method of making human anti-TNF-alpha antibody
ES2535734T3 (es) 2008-10-20 2015-05-14 Abbvie Inc. Aislamiento y purificación de anticuerpos mediante cromatografía de afinidad con la proteína A
TW201028433A (en) 2008-10-20 2010-08-01 Abbott Lab Viral inactivation during purification of antibodies
WO2012149197A2 (en) 2011-04-27 2012-11-01 Abbott Laboratories Methods for controlling the galactosylation profile of recombinantly-expressed proteins
EP2732027B1 (de) * 2011-07-12 2017-03-01 Foodchek Systems, Inc. Kulturmedium, verfahren zur kultivierung von salmonella und e. coli sowie verfahren zur erkennung von salmonella und e. coli
US9067990B2 (en) 2013-03-14 2015-06-30 Abbvie, Inc. Protein purification using displacement chromatography
WO2013158273A1 (en) 2012-04-20 2013-10-24 Abbvie Inc. Methods to modulate c-terminal lysine variant distribution
WO2013158279A1 (en) 2012-04-20 2013-10-24 Abbvie Inc. Protein purification methods to reduce acidic species
US9505833B2 (en) 2012-04-20 2016-11-29 Abbvie Inc. Human antibodies that bind human TNF-alpha and methods of preparing the same
US20130281355A1 (en) * 2012-04-24 2013-10-24 Genentech, Inc. Cell culture compositions and methods for polypeptide production
US9249182B2 (en) 2012-05-24 2016-02-02 Abbvie, Inc. Purification of antibodies using hydrophobic interaction chromatography
US9206390B2 (en) 2012-09-02 2015-12-08 Abbvie, Inc. Methods to control protein heterogeneity
US9512214B2 (en) 2012-09-02 2016-12-06 Abbvie, Inc. Methods to control protein heterogeneity
EP2767273A1 (de) 2013-02-15 2014-08-20 Universitätsklinikum Erlangen Todassoziierte Proteinkinasen, Hemmer und Aktivatoren für die Verwendung in pharmazeutischen Zusammensetzungen und vorhersagbare Medizin
US9499614B2 (en) 2013-03-14 2016-11-22 Abbvie Inc. Methods for modulating protein glycosylation profiles of recombinant protein therapeutics using monosaccharides and oligosaccharides
WO2014159579A1 (en) 2013-03-14 2014-10-02 Abbvie Inc. MUTATED ANTI-TNFα ANTIBODIES AND METHODS OF THEIR USE
US9017687B1 (en) 2013-10-18 2015-04-28 Abbvie, Inc. Low acidic species compositions and methods for producing and using the same using displacement chromatography
WO2015051293A2 (en) 2013-10-04 2015-04-09 Abbvie, Inc. Use of metal ions for modulation of protein glycosylation profiles of recombinant proteins
US9085618B2 (en) 2013-10-18 2015-07-21 Abbvie, Inc. Low acidic species compositions and methods for producing and using the same
US9181337B2 (en) 2013-10-18 2015-11-10 Abbvie, Inc. Modulated lysine variant species compositions and methods for producing and using the same
US8946395B1 (en) 2013-10-18 2015-02-03 Abbvie Inc. Purification of proteins using hydrophobic interaction chromatography
WO2015073884A2 (en) 2013-11-15 2015-05-21 Abbvie, Inc. Glycoengineered binding protein compositions
CA3033333A1 (en) 2015-09-21 2017-03-30 The Board Of Trustees Of The Leland Stanford Junior University Nutritional treatment for cancer
KR102334203B1 (ko) * 2017-08-09 2021-12-02 가부시키가이샤 만다무 불사화(不死化) 땀샘 근상피 세포
WO2019118519A1 (en) 2017-12-11 2019-06-20 Filtricine, Inc. Compositions, methods, kits and systems for cancer treatment and metabolic intervention therapy
CN111172114B (zh) * 2019-12-10 2021-11-30 上海中医药大学附属岳阳中西医结合医院 一种人源化肠癌前病变永生化上皮细胞系、构建方法及其应用
CN114891722A (zh) * 2022-05-13 2022-08-12 广东省农业科学院动物卫生研究所 禽肠道上皮细胞及其制备方法和应用
CN116083342A (zh) * 2023-01-16 2023-05-09 细新(上海)医疗科技有限公司 一种原代上皮细胞的培养体系和应用

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4229531A (en) * 1978-12-29 1980-10-21 Monsanto Company Production of tumor angiogenesis factor by cell culture
DE3711699A1 (de) * 1987-04-07 1988-11-10 Fraunhofer Ges Forschung Medium zur kultivierung und proliferation von epithelialen zelltypen
US4885238A (en) * 1987-10-30 1989-12-05 The United States Of America As Represented By The Department Of Health And Human Services Immortalized human bronchial epitherial mesothelial cell lines
AU2921289A (en) * 1987-12-09 1989-07-19 Invitron Corporation Human cell life extension
US5093259A (en) * 1988-07-07 1992-03-03 Oak Ridge Associated Universities, Inc. Continuous cell-line tamarin adenocarcinoma of the colon
US5665589A (en) * 1988-12-14 1997-09-09 The United States Of America As Represented By The Department Of Health And Human Services Human liver epithelial cell lines
US5529920A (en) * 1988-12-14 1996-06-25 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Human liver epithelial cell line and culture media therefor
US5376542A (en) 1992-04-27 1994-12-27 Georgetown University Method for producing immortalized cell lines using human papilluma virus genes
ATE172245T1 (de) 1992-07-06 1998-10-15 Nestle Sa Milchbakterien
US5462870A (en) * 1993-04-23 1995-10-31 Wayne State University Human diploid salivary gland epithelial cell lines
US5672498A (en) * 1993-12-28 1997-09-30 The Gillete Company Human corneal epithelial cell lines with extended lifespan
US5610043A (en) * 1994-04-28 1997-03-11 The United States Of America As Represented By The Department Of Health And Human Services Human prostatic cell lines immortalized by adenovirus 12-simian virus 40 (AD12/SV40) hybrid virus
PT802257E (pt) * 1996-04-19 2003-01-31 Nestle Sa Linhagem imortalizada de celulas epiteliais do colon humano

Also Published As

Publication number Publication date
NO971757L (no) 1997-10-20
DE69623109T2 (de) 2002-12-12
JPH1028580A (ja) 1998-02-03
AU1893397A (en) 1997-10-23
FI120352B (fi) 2009-09-30
NO319494B1 (no) 2005-08-22
EP0802257B1 (de) 2002-08-21
PT802257E (pt) 2003-01-31
US6194203B1 (en) 2001-02-27
FI971628A0 (fi) 1997-04-17
DE69623109D1 (de) 2002-09-26
ES2180689T3 (es) 2003-02-16
NO971757D0 (no) 1997-04-17
JP3931212B2 (ja) 2007-06-13
NZ314614A (en) 1999-04-29
US6399381B1 (en) 2002-06-04
US6395542B1 (en) 2002-05-28
RU2220201C2 (ru) 2003-12-27
CA2202923A1 (en) 1997-10-19
EP0802257A1 (de) 1997-10-22
FI971628A (fi) 1997-10-20
AU733913B2 (en) 2001-05-31
DK0802257T3 (da) 2002-10-28
CA2202923C (en) 2008-06-10

Similar Documents

Publication Publication Date Title
ATE222598T1 (de) Menschliche immortalisierte colon- epithelialzellen
Tong et al. Long-term culture of rat liver cell spheroids in hormonally defined media
Peehl et al. Growth and differentiation of human keratinocytes without a feeder layer or conditioned medium
EP2752484B1 (de) Verfahren zur herstellung eines basischen kulturmediums für mesenchymale stammzellen, basisches kulturmedium für mesenchymale stammzellen und
US5712163A (en) Chemically defined cell culture media and system and methods for use, particularly for culturing epithelial cells
US5342777A (en) Cell culture medium for human liver epithelial cell line
WO1998059035A3 (en) Serum-free cell growth medium
Brandi et al. Bovine parathyroid cells: cultures maintained for more than 140 population doublings.
US11485955B2 (en) Formula of serum-free medium for human pluripotent stem cells
TW200927927A (en) Stem cell medium
Kaighn et al. Growth control of prostatic carcinoma cells in serum-free media: interrelationship of hormone response, cell density, and nutrient media.
CN100506977C (zh) 一种中国仓鼠卵巢细胞扩增培养基及其用途
Ham Dermal fibroblasts
Webber et al. Serum‐free culture of rabbit meniscal fibrochondrocytes: Proliferative response
Wu et al. Replacement of serum in cell culture by hormones: A study of hormonal regulation of cell growth and specific gene expression
CN111440764A (zh) 间充质干细胞的无血清培养基及间充质干细胞的临床级规模化培养方法
Gasser et al. Long-term multiplication of the Chinese hamster ovary (CHO) cell line in a serum-free medium
Washizu et al. Amino acid supplementation improves cell-specific functions of the rat hepatocytes exposed to human plasma
Roberts et al. A novel epithelial cell from neonatal rat lung: isolation and differentiated phenotype
Agy et al. Protein-free medium for C-1300 mouse neuroblastoma cells
Riss et al. Rat pituitary tumor cells in serum-free culture. I. Selection of thyroid hormone-responsive and autonomous cells
RU2795065C1 (ru) Состав бессывороточной питательной среды для культивирования мезенхимных стволовых клеток свиньи
Suryawan et al. The primary cell culture system for preadipocytes
Kitano Serum‐free media
CN117625519A (zh) 促肌肉干细胞体外存活和增殖的无胎牛血清培养基及其应用

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification