PT802257E - Linhagem imortalizada de celulas epiteliais do colon humano - Google Patents

Linhagem imortalizada de celulas epiteliais do colon humano

Info

Publication number
PT802257E
PT802257E PT96201064T PT96201064T PT802257E PT 802257 E PT802257 E PT 802257E PT 96201064 T PT96201064 T PT 96201064T PT 96201064 T PT96201064 T PT 96201064T PT 802257 E PT802257 E PT 802257E
Authority
PT
Portugal
Prior art keywords
human colon
epithelial cells
colon epithelial
cells
immortalising
Prior art date
Application number
PT96201064T
Other languages
English (en)
Inventor
Stephanie Blum
Andrea Pfeifer
Yvonne Troumvoukis
Original Assignee
Nestle Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nestle Sa filed Critical Nestle Sa
Publication of PT802257E publication Critical patent/PT802257E/pt

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0679Cells of the gastro-intestinal tract
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00Specific components of cell culture medium
    • C12N2500/05Inorganic components
    • C12N2500/10Metals; Metal chelators
    • C12N2500/20Transition metals
    • C12N2500/24Iron; Fe chelators; Transferrin
    • C12N2500/25Insulin-transferrin; Insulin-transferrin-selenium
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00Specific components of cell culture medium
    • C12N2500/30Organic components
    • C12N2500/38Vitamins
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00Specific components of cell culture medium
    • C12N2500/90Serum-free medium, which may still contain naturally-sourced components
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10Growth factors
    • C12N2501/11Epidermal growth factor [EGF]
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/30Hormones
    • C12N2501/38Hormones with nuclear receptors
    • C12N2501/39Steroid hormones
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/30Hormones
    • C12N2501/38Hormones with nuclear receptors
    • C12N2501/395Thyroid hormones
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2503/00Use of cells in diagnostics
    • C12N2503/02Drug screening
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2510/00Genetically modified cells
    • C12N2510/04Immortalised cells

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Prostheses (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
PT96201064T 1996-04-19 1996-04-19 Linhagem imortalizada de celulas epiteliais do colon humano PT802257E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP96201064A EP0802257B1 (fr) 1996-04-19 1996-04-19 Lignée immortalisée de cellules épithéliales du colon humain

Publications (1)

Publication Number Publication Date
PT802257E true PT802257E (pt) 2003-01-31

Family

ID=8223895

Family Applications (1)

Application Number Title Priority Date Filing Date
PT96201064T PT802257E (pt) 1996-04-19 1996-04-19 Linhagem imortalizada de celulas epiteliais do colon humano

Country Status (14)

Country Link
US (3) US6194203B1 (pt)
EP (1) EP0802257B1 (pt)
JP (1) JP3931212B2 (pt)
AT (1) ATE222598T1 (pt)
AU (1) AU733913B2 (pt)
CA (1) CA2202923C (pt)
DE (1) DE69623109T2 (pt)
DK (1) DK0802257T3 (pt)
ES (1) ES2180689T3 (pt)
FI (1) FI120352B (pt)
NO (1) NO319494B1 (pt)
NZ (1) NZ314614A (pt)
PT (1) PT802257E (pt)
RU (1) RU2220201C2 (pt)

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ES2180689T3 (es) * 1996-04-19 2003-02-16 Nestle Sa Linea inmortalizada de celulas epiteliales del colon humano.
DE69636755T2 (de) 1996-12-24 2007-10-11 Société des Produits Nestlé S.A. Immortalisierte menschliche Epithelzell-Linie
US5960073A (en) * 1997-04-03 1999-09-28 Genesys Telecommunications Laboratories , Inc. Method and apparatus for providing an interactive home agent with access to call center functionality and resources
DE19755023C2 (de) * 1997-12-11 2000-03-09 Celanese Chem Europe Gmbh Katalysator und Verfahren zur Herstellung von Vinylacetat
EP1048724A1 (en) * 1999-04-27 2000-11-02 Transgene S.A. Human myoblast cell lines and their uses
ES2241246T3 (es) * 1999-04-27 2005-10-16 Transgene S.A. Proceso para la produccion de lineas celulares de mamiferos.
US7078232B2 (en) 1999-08-19 2006-07-18 Artecel, Inc. Adipose tissue-derived adult stem or stromal cells for the repair of articular cartilage fractures and uses thereof
US6429013B1 (en) * 1999-08-19 2002-08-06 Artecel Science, Inc. Use of adipose tissue-derived stromal cells for chondrocyte differentiation and cartilage repair
US6416999B1 (en) * 2000-04-07 2002-07-09 Raven Biotechnologies, Inc. Human Müllerian duct-derived epithelial cells and methods of isolation and uses thereof
EP1360314B1 (en) * 2001-02-15 2009-01-14 Centocor, Inc. Chemically defined medium for cultured mammalian cells
CA2479072A1 (en) * 2002-03-12 2003-12-18 Surface Logix, Inc. Assay device that analyzes the absorption, metabolism, permeability and/or toxicity of a candidate compound
GB0212405D0 (en) * 2002-05-29 2002-07-10 Insignion Holdings Ltd Composition and its therapeutic use
US7115563B2 (en) * 2002-05-29 2006-10-03 Insignion Holding Limited Composition and its therapeutic use
EP1768669B1 (en) * 2004-07-19 2009-11-11 Institut de Recherche pour le Développement ( IRD) Pharmaceutical compositions for the treatment of leishmaniasis
US8273553B2 (en) * 2004-11-02 2012-09-25 Ares Trading S.A. Production of growth hormone in serum-free cell culture medium for mammalian cells
SI1807504T1 (sl) 2004-11-02 2011-05-31 Ares Trading Sa Brezserumski celiäśni kultivacijski medij za celice sesalcev
EP1917276B1 (en) 2005-08-26 2018-03-21 Ares Trading S.A. Process for the preparation of glycosylated interferon beta
AU2007294731B2 (en) 2006-09-13 2014-04-17 Abbvie Inc. Cell culture improvements
US8911964B2 (en) 2006-09-13 2014-12-16 Abbvie Inc. Fed-batch method of making human anti-TNF-alpha antibody
CA2911256A1 (en) * 2008-10-20 2010-12-09 Robert K. Hickman Isolation and purification of antibodies using protein a affinity chromatography
NZ592097A (en) 2008-10-20 2013-01-25 Abbott Lab Viral inactivation during purification of il-12 and il-18 antibodies
WO2012149197A2 (en) 2011-04-27 2012-11-01 Abbott Laboratories Methods for controlling the galactosylation profile of recombinantly-expressed proteins
AU2012283667B2 (en) * 2011-07-12 2015-07-09 Foodchek Systems, Inc. Culture medium, method for culturing Salmonella and E. coli and method for detecting Salmonella and E. coli
US9334319B2 (en) 2012-04-20 2016-05-10 Abbvie Inc. Low acidic species compositions
WO2013158273A1 (en) 2012-04-20 2013-10-24 Abbvie Inc. Methods to modulate c-terminal lysine variant distribution
US9067990B2 (en) 2013-03-14 2015-06-30 Abbvie, Inc. Protein purification using displacement chromatography
US20130281355A1 (en) * 2012-04-24 2013-10-24 Genentech, Inc. Cell culture compositions and methods for polypeptide production
WO2013176754A1 (en) 2012-05-24 2013-11-28 Abbvie Inc. Novel purification of antibodies using hydrophobic interaction chromatography
US9512214B2 (en) 2012-09-02 2016-12-06 Abbvie, Inc. Methods to control protein heterogeneity
KR20150043523A (ko) 2012-09-02 2015-04-22 애브비 인코포레이티드 단백질 불균일성의 제어 방법
EP2767273A1 (en) 2013-02-15 2014-08-20 Universitätsklinikum Erlangen Death-associated protein kinases, inhibitors and activators thereof for use in pharmaceutical compositions and in predictive medicine
SG11201507230PA (en) 2013-03-12 2015-10-29 Abbvie Inc Human antibodies that bind human tnf-alpha and methods of preparing the same
WO2014151878A2 (en) 2013-03-14 2014-09-25 Abbvie Inc. Methods for modulating protein glycosylation profiles of recombinant protein therapeutics using monosaccharides and oligosacharides
US9017687B1 (en) 2013-10-18 2015-04-28 Abbvie, Inc. Low acidic species compositions and methods for producing and using the same using displacement chromatography
WO2014159579A1 (en) 2013-03-14 2014-10-02 Abbvie Inc. MUTATED ANTI-TNFα ANTIBODIES AND METHODS OF THEIR USE
US9598667B2 (en) 2013-10-04 2017-03-21 Abbvie Inc. Use of metal ions for modulation of protein glycosylation profiles of recombinant proteins
US9085618B2 (en) 2013-10-18 2015-07-21 Abbvie, Inc. Low acidic species compositions and methods for producing and using the same
US9181337B2 (en) 2013-10-18 2015-11-10 Abbvie, Inc. Modulated lysine variant species compositions and methods for producing and using the same
US8946395B1 (en) 2013-10-18 2015-02-03 Abbvie Inc. Purification of proteins using hydrophobic interaction chromatography
WO2015073884A2 (en) 2013-11-15 2015-05-21 Abbvie, Inc. Glycoengineered binding protein compositions
WO2017053328A1 (en) * 2015-09-21 2017-03-30 The Board Of Trustees Of The Leland Stanford Junior University Nutritional treatment for cancer
EP3666889A4 (en) * 2017-08-09 2021-04-28 Mandom Corporation IMMORTALIZED SWEAT GLANDS MYOEPITHELIAL CELL
WO2019118519A1 (en) 2017-12-11 2019-06-20 Filtricine, Inc. Compositions, methods, kits and systems for cancer treatment and metabolic intervention therapy
CN111172114B (zh) * 2019-12-10 2021-11-30 上海中医药大学附属岳阳中西医结合医院 一种人源化肠癌前病变永生化上皮细胞系、构建方法及其应用
CN114891722A (zh) * 2022-05-13 2022-08-12 广东省农业科学院动物卫生研究所 禽肠道上皮细胞及其制备方法和应用
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Also Published As

Publication number Publication date
DE69623109T2 (de) 2002-12-12
NO971757D0 (no) 1997-04-17
NZ314614A (en) 1999-04-29
JPH1028580A (ja) 1998-02-03
AU1893397A (en) 1997-10-23
EP0802257A1 (fr) 1997-10-22
ES2180689T3 (es) 2003-02-16
FI971628A (fi) 1997-10-20
AU733913B2 (en) 2001-05-31
ATE222598T1 (de) 2002-09-15
NO971757L (no) 1997-10-20
US6194203B1 (en) 2001-02-27
FI120352B (fi) 2009-09-30
NO319494B1 (no) 2005-08-22
CA2202923A1 (en) 1997-10-19
US6395542B1 (en) 2002-05-28
DE69623109D1 (de) 2002-09-26
US6399381B1 (en) 2002-06-04
CA2202923C (en) 2008-06-10
RU2220201C2 (ru) 2003-12-27
EP0802257B1 (fr) 2002-08-21
FI971628A0 (fi) 1997-04-17
DK0802257T3 (da) 2002-10-28
JP3931212B2 (ja) 2007-06-13

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