FI120352B - Menetelmä ihmisen koolonin epiteelisolujen immortalisoimiseksi, ihmisen koolonin epiteelisolujen viljelemiseen ja immortalisoimiseen sopiva seerumia sisältämätön viljelyalusta, ihmisen koolonin immortalisoitu epiteelisolulinja, menetelmä suolikanavan.... - Google Patents

Menetelmä ihmisen koolonin epiteelisolujen immortalisoimiseksi, ihmisen koolonin epiteelisolujen viljelemiseen ja immortalisoimiseen sopiva seerumia sisältämätön viljelyalusta, ihmisen koolonin immortalisoitu epiteelisolulinja, menetelmä suolikanavan.... Download PDF

Info

Publication number
FI120352B
FI120352B FI971628A FI971628A FI120352B FI 120352 B FI120352 B FI 120352B FI 971628 A FI971628 A FI 971628A FI 971628 A FI971628 A FI 971628A FI 120352 B FI120352 B FI 120352B
Authority
FI
Finland
Prior art keywords
cells
epithelial cells
cell line
human colon
colon epithelial
Prior art date
Application number
FI971628A
Other languages
English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI971628A0 (fi
FI971628A (fi
Inventor
Stephanie Blum
Original Assignee
Nestle Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nestle Sa filed Critical Nestle Sa
Publication of FI971628A0 publication Critical patent/FI971628A0/fi
Publication of FI971628A publication Critical patent/FI971628A/fi
Application granted granted Critical
Publication of FI120352B publication Critical patent/FI120352B/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0679—Cells of the gastro-intestinal tract
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/05—Inorganic components
    • C12N2500/10—Metals; Metal chelators
    • C12N2500/20—Transition metals
    • C12N2500/24—Iron; Fe chelators; Transferrin
    • C12N2500/25—Insulin-transferrin; Insulin-transferrin-selenium
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/30—Organic components
    • C12N2500/38—Vitamins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/90—Serum-free medium, which may still contain naturally-sourced components
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
    • C12N2501/11—Epidermal growth factor [EGF]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/30—Hormones
    • C12N2501/38—Hormones with nuclear receptors
    • C12N2501/39—Steroid hormones
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/30—Hormones
    • C12N2501/38—Hormones with nuclear receptors
    • C12N2501/395—Thyroid hormones
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2503/00—Use of cells in diagnostics
    • C12N2503/02—Drug screening
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2510/00—Genetically modified cells
    • C12N2510/04—Immortalised cells

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Prostheses (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
FI971628A 1996-04-19 1997-04-17 Menetelmä ihmisen koolonin epiteelisolujen immortalisoimiseksi, ihmisen koolonin epiteelisolujen viljelemiseen ja immortalisoimiseen sopiva seerumia sisältämätön viljelyalusta, ihmisen koolonin immortalisoitu epiteelisolulinja, menetelmä suolikanavan.... FI120352B (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP96201064A EP0802257B1 (de) 1996-04-19 1996-04-19 Menschliche immortalisierte Colon-Epithelialzellen
EP96201064 1996-04-19

Publications (3)

Publication Number Publication Date
FI971628A0 FI971628A0 (fi) 1997-04-17
FI971628A FI971628A (fi) 1997-10-20
FI120352B true FI120352B (fi) 2009-09-30

Family

ID=8223895

Family Applications (1)

Application Number Title Priority Date Filing Date
FI971628A FI120352B (fi) 1996-04-19 1997-04-17 Menetelmä ihmisen koolonin epiteelisolujen immortalisoimiseksi, ihmisen koolonin epiteelisolujen viljelemiseen ja immortalisoimiseen sopiva seerumia sisältämätön viljelyalusta, ihmisen koolonin immortalisoitu epiteelisolulinja, menetelmä suolikanavan....

Country Status (14)

Country Link
US (3) US6194203B1 (de)
EP (1) EP0802257B1 (de)
JP (1) JP3931212B2 (de)
AT (1) ATE222598T1 (de)
AU (1) AU733913B2 (de)
CA (1) CA2202923C (de)
DE (1) DE69623109T2 (de)
DK (1) DK0802257T3 (de)
ES (1) ES2180689T3 (de)
FI (1) FI120352B (de)
NO (1) NO319494B1 (de)
NZ (1) NZ314614A (de)
PT (1) PT802257E (de)
RU (1) RU2220201C2 (de)

Families Citing this family (46)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2180689T3 (es) * 1996-04-19 2003-02-16 Nestle Sa Linea inmortalizada de celulas epiteliales del colon humano.
ATE347587T1 (de) 1996-12-24 2006-12-15 Nestle Sa Immortalisierte menschliche epithelzell-linie aus kornea
US5960073A (en) * 1997-04-03 1999-09-28 Genesys Telecommunications Laboratories , Inc. Method and apparatus for providing an interactive home agent with access to call center functionality and resources
DE19755023C2 (de) * 1997-12-11 2000-03-09 Celanese Chem Europe Gmbh Katalysator und Verfahren zur Herstellung von Vinylacetat
DK1048725T3 (da) * 1999-04-27 2005-08-22 Transgene Sa Fremgangsmåde til fremstilling af pattedyrcellelinjer
EP1048724A1 (de) * 1999-04-27 2000-11-02 Transgene S.A. Humane Myoblastzellinien und deren Anwendungen
US6429013B1 (en) * 1999-08-19 2002-08-06 Artecel Science, Inc. Use of adipose tissue-derived stromal cells for chondrocyte differentiation and cartilage repair
US7078232B2 (en) * 1999-08-19 2006-07-18 Artecel, Inc. Adipose tissue-derived adult stem or stromal cells for the repair of articular cartilage fractures and uses thereof
US6416999B1 (en) 2000-04-07 2002-07-09 Raven Biotechnologies, Inc. Human Müllerian duct-derived epithelial cells and methods of isolation and uses thereof
US6900056B2 (en) * 2001-02-15 2005-05-31 Centocor, Inc. Chemically defined medium for cultured mammalian cells
US20030215941A1 (en) * 2002-03-12 2003-11-20 Stewart Campbell Assay device that analyzes the absorption, metabolism, permeability and/or toxicity of a candidate compound
GB0212405D0 (en) * 2002-05-29 2002-07-10 Insignion Holdings Ltd Composition and its therapeutic use
US7115563B2 (en) * 2002-05-29 2006-10-03 Insignion Holding Limited Composition and its therapeutic use
ATE447953T1 (de) * 2004-07-19 2009-11-15 Inst Rech Developpement Ird Pharmazeutische zusammensetzungen zur behandlung von leishmaniasis
US8273553B2 (en) * 2004-11-02 2012-09-25 Ares Trading S.A. Production of growth hormone in serum-free cell culture medium for mammalian cells
ZA200702434B (en) 2004-11-02 2008-08-27 Ares Trading Sa Serum-free cell culture medium for mammalian cells
EP2390263A1 (de) 2005-08-26 2011-11-30 Ares Trading S.A. Verfahren zur Herstellung von glycosyliertem Interferon beta
MY185872A (en) 2006-09-13 2021-06-14 Abbvie Inc Cell culture improvements
US8911964B2 (en) 2006-09-13 2014-12-16 Abbvie Inc. Fed-batch method of making human anti-TNF-alpha antibody
TW201028433A (en) 2008-10-20 2010-08-01 Abbott Lab Viral inactivation during purification of antibodies
WO2010141039A1 (en) 2008-10-20 2010-12-09 Abbott Laboratories Isolation and purification of antibodies using protein a affinity chromatography
EP2702077A2 (de) 2011-04-27 2014-03-05 AbbVie Inc. Verfahren zur steuerung des galactosylierungsprofil von rekombinant exprimierten proteinen
GB2497249B (en) * 2011-07-12 2016-12-28 Foodchek Systems Inc Culture medium,method for culturing salmonella and e.coli and method for detecting salmonella and e.coli
US9150645B2 (en) 2012-04-20 2015-10-06 Abbvie, Inc. Cell culture methods to reduce acidic species
US9067990B2 (en) 2013-03-14 2015-06-30 Abbvie, Inc. Protein purification using displacement chromatography
WO2013158273A1 (en) 2012-04-20 2013-10-24 Abbvie Inc. Methods to modulate c-terminal lysine variant distribution
US20130281355A1 (en) * 2012-04-24 2013-10-24 Genentech, Inc. Cell culture compositions and methods for polypeptide production
US9249182B2 (en) 2012-05-24 2016-02-02 Abbvie, Inc. Purification of antibodies using hydrophobic interaction chromatography
US9206390B2 (en) 2012-09-02 2015-12-08 Abbvie, Inc. Methods to control protein heterogeneity
US9512214B2 (en) 2012-09-02 2016-12-06 Abbvie, Inc. Methods to control protein heterogeneity
EP2767273A1 (de) 2013-02-15 2014-08-20 Universitätsklinikum Erlangen Todassoziierte Proteinkinasen, Hemmer und Aktivatoren für die Verwendung in pharmazeutischen Zusammensetzungen und vorhersagbare Medizin
WO2014143205A1 (en) 2013-03-12 2014-09-18 Abbvie Inc. Human antibodies that bind human tnf-alpha and methods of preparing the same
US9499614B2 (en) 2013-03-14 2016-11-22 Abbvie Inc. Methods for modulating protein glycosylation profiles of recombinant protein therapeutics using monosaccharides and oligosaccharides
US9017687B1 (en) 2013-10-18 2015-04-28 Abbvie, Inc. Low acidic species compositions and methods for producing and using the same using displacement chromatography
US8921526B2 (en) 2013-03-14 2014-12-30 Abbvie, Inc. Mutated anti-TNFα antibodies and methods of their use
US9598667B2 (en) 2013-10-04 2017-03-21 Abbvie Inc. Use of metal ions for modulation of protein glycosylation profiles of recombinant proteins
US9181337B2 (en) 2013-10-18 2015-11-10 Abbvie, Inc. Modulated lysine variant species compositions and methods for producing and using the same
US9085618B2 (en) 2013-10-18 2015-07-21 Abbvie, Inc. Low acidic species compositions and methods for producing and using the same
US8946395B1 (en) 2013-10-18 2015-02-03 Abbvie Inc. Purification of proteins using hydrophobic interaction chromatography
WO2015073884A2 (en) 2013-11-15 2015-05-21 Abbvie, Inc. Glycoengineered binding protein compositions
EP3352586A4 (de) 2015-09-21 2019-05-15 The Board Of Trustees Of The Leland Stanford Junior University Ernährungsbehandlung bei krebserkrankungen
US11060061B2 (en) * 2017-08-09 2021-07-13 Mandom Corporation Immortalized sweat gland myoepithelial cell
EP3723772A4 (de) 2017-12-11 2021-09-08 Filtricine, Inc. Zusammensetzungen, verfahren, kits und systeme zur krebsbehandlung und stoffwechselinterventionstherapie
CN111172114B (zh) * 2019-12-10 2021-11-30 上海中医药大学附属岳阳中西医结合医院 一种人源化肠癌前病变永生化上皮细胞系、构建方法及其应用
CN114891722A (zh) * 2022-05-13 2022-08-12 广东省农业科学院动物卫生研究所 禽肠道上皮细胞及其制备方法和应用
CN116083342A (zh) * 2023-01-16 2023-05-09 细新(上海)医疗科技有限公司 一种原代上皮细胞的培养体系和应用

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4229531A (en) * 1978-12-29 1980-10-21 Monsanto Company Production of tumor angiogenesis factor by cell culture
DE3711699A1 (de) * 1987-04-07 1988-11-10 Fraunhofer Ges Forschung Medium zur kultivierung und proliferation von epithelialen zelltypen
US4885238A (en) * 1987-10-30 1989-12-05 The United States Of America As Represented By The Department Of Health And Human Services Immortalized human bronchial epitherial mesothelial cell lines
WO1989005862A1 (en) * 1987-12-09 1989-06-29 Invitron Corporation Human cell life extension
US5093259A (en) * 1988-07-07 1992-03-03 Oak Ridge Associated Universities, Inc. Continuous cell-line tamarin adenocarcinoma of the colon
US5665589A (en) * 1988-12-14 1997-09-09 The United States Of America As Represented By The Department Of Health And Human Services Human liver epithelial cell lines
US5529920A (en) * 1988-12-14 1996-06-25 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Human liver epithelial cell line and culture media therefor
US5376542A (en) 1992-04-27 1994-12-27 Georgetown University Method for producing immortalized cell lines using human papilluma virus genes
ATE172245T1 (de) 1992-07-06 1998-10-15 Nestle Sa Milchbakterien
US5462870A (en) * 1993-04-23 1995-10-31 Wayne State University Human diploid salivary gland epithelial cell lines
US5672498A (en) * 1993-12-28 1997-09-30 The Gillete Company Human corneal epithelial cell lines with extended lifespan
US5610043A (en) * 1994-04-28 1997-03-11 The United States Of America As Represented By The Department Of Health And Human Services Human prostatic cell lines immortalized by adenovirus 12-simian virus 40 (AD12/SV40) hybrid virus
ES2180689T3 (es) * 1996-04-19 2003-02-16 Nestle Sa Linea inmortalizada de celulas epiteliales del colon humano.

Also Published As

Publication number Publication date
AU1893397A (en) 1997-10-23
NZ314614A (en) 1999-04-29
DK0802257T3 (da) 2002-10-28
CA2202923C (en) 2008-06-10
EP0802257B1 (de) 2002-08-21
JPH1028580A (ja) 1998-02-03
CA2202923A1 (en) 1997-10-19
NO319494B1 (no) 2005-08-22
FI971628A0 (fi) 1997-04-17
FI971628A (fi) 1997-10-20
DE69623109D1 (de) 2002-09-26
NO971757D0 (no) 1997-04-17
RU2220201C2 (ru) 2003-12-27
ES2180689T3 (es) 2003-02-16
EP0802257A1 (de) 1997-10-22
US6194203B1 (en) 2001-02-27
NO971757L (no) 1997-10-20
JP3931212B2 (ja) 2007-06-13
ATE222598T1 (de) 2002-09-15
US6395542B1 (en) 2002-05-28
PT802257E (pt) 2003-01-31
US6399381B1 (en) 2002-06-04
DE69623109T2 (de) 2002-12-12
AU733913B2 (en) 2001-05-31

Similar Documents

Publication Publication Date Title
FI120352B (fi) Menetelmä ihmisen koolonin epiteelisolujen immortalisoimiseksi, ihmisen koolonin epiteelisolujen viljelemiseen ja immortalisoimiseen sopiva seerumia sisältämätön viljelyalusta, ihmisen koolonin immortalisoitu epiteelisolulinja, menetelmä suolikanavan....
US11530385B2 (en) Hormone responsive tissue culture system and uses thereof
US20050260748A1 (en) Adult stem cells and uses thereof
US9951315B2 (en) Immortalization of epithelial cells and methods of use
US8715954B2 (en) Method of producing C3A serum-free clonal cell line
CN1439049A (zh) 衍生自多能干细胞的肝细胞谱系细胞
US7294509B2 (en) Pre-adipose cell lines
CN1205737A (zh) 改良无限增殖化人类皮肤细胞系和用于其生产的新型无血清培育基
ES2229219T3 (es) Lineas celulares humanas inmortalizadas que contienen genes del citocromo p450 exogenos.
US20060154235A1 (en) Human hepatocyte-like cells and uses thereof
EP1704227A1 (de) Immortalisierte hepatozyten
EP0851028B1 (de) Immortalisierte menschliche Epithelzell-Linie aus Kornea
EP0929661A1 (de) Neuartiges verfahren der kultivierung menschlicher epithelzellenzur identifizierung von therapeutika und diagnostika gegen krebs
Stacey et al. Immortalisation of primary cells
Yoshizato Growth potential of adult hepatocytes in mammals: Highly replicative small hepatocytes with liver progenitor‐like traits
Brash et al. Overview of human cells in genetic research: Altered phenotypes in human cells caused by transferred genes
US8133729B2 (en) Biomimetic urothelium
Grisham et al. Clonal analysis of neoplastic transformation in cultured diploid rat liver epithelial cells
WO2002064017A2 (en) Immortalized human prostatic cancer cell lines
WO2002064018A2 (en) Immortalized human familial prostatic cancer cell lines

Legal Events

Date Code Title Description
FG Patent granted

Ref document number: 120352

Country of ref document: FI

MM Patent lapsed