FI120352B - Menetelmä ihmisen koolonin epiteelisolujen immortalisoimiseksi, ihmisen koolonin epiteelisolujen viljelemiseen ja immortalisoimiseen sopiva seerumia sisältämätön viljelyalusta, ihmisen koolonin immortalisoitu epiteelisolulinja, menetelmä suolikanavan.... - Google Patents

Menetelmä ihmisen koolonin epiteelisolujen immortalisoimiseksi, ihmisen koolonin epiteelisolujen viljelemiseen ja immortalisoimiseen sopiva seerumia sisältämätön viljelyalusta, ihmisen koolonin immortalisoitu epiteelisolulinja, menetelmä suolikanavan.... Download PDF

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FI120352B
FI120352B FI971628A FI971628A FI120352B FI 120352 B FI120352 B FI 120352B FI 971628 A FI971628 A FI 971628A FI 971628 A FI971628 A FI 971628A FI 120352 B FI120352 B FI 120352B
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cells
epithelial cells
cell line
human colon
colon epithelial
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FI971628A
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FI971628A (fi
FI971628A0 (fi
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Stephanie Blum
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Nestle Sa
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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0679Cells of the gastro-intestinal tract
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N2500/00Specific components of cell culture medium
    • C12N2500/05Inorganic components
    • C12N2500/10Metals; Metal chelators
    • C12N2500/20Transition metals
    • C12N2500/24Iron; Fe chelators; Transferrin
    • C12N2500/25Insulin-transferrin; Insulin-transferrin-selenium
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    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N2500/00Specific components of cell culture medium
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    • C12N2500/38Vitamins
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    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N2500/00Specific components of cell culture medium
    • C12N2500/90Serum-free medium, which may still contain naturally-sourced components
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    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10Growth factors
    • C12N2501/11Epidermal growth factor [EGF]
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    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/30Hormones
    • C12N2501/38Hormones with nuclear receptors
    • C12N2501/39Steroid hormones
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    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/30Hormones
    • C12N2501/38Hormones with nuclear receptors
    • C12N2501/395Thyroid hormones
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N2503/00Use of cells in diagnostics
    • C12N2503/02Drug screening
    • CCHEMISTRY; METALLURGY
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    • C12N2510/00Genetically modified cells
    • C12N2510/04Immortalised cells

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Wood Science & Technology (AREA)
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  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Prostheses (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
FI971628A 1996-04-19 1997-04-17 Menetelmä ihmisen koolonin epiteelisolujen immortalisoimiseksi, ihmisen koolonin epiteelisolujen viljelemiseen ja immortalisoimiseen sopiva seerumia sisältämätön viljelyalusta, ihmisen koolonin immortalisoitu epiteelisolulinja, menetelmä suolikanavan.... FI120352B (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP96201064A EP0802257B1 (de) 1996-04-19 1996-04-19 Menschliche immortalisierte Colon-Epithelialzellen
EP96201064 1996-04-19

Publications (3)

Publication Number Publication Date
FI971628A0 FI971628A0 (fi) 1997-04-17
FI971628A FI971628A (fi) 1997-10-20
FI120352B true FI120352B (fi) 2009-09-30

Family

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Family Applications (1)

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FI971628A FI120352B (fi) 1996-04-19 1997-04-17 Menetelmä ihmisen koolonin epiteelisolujen immortalisoimiseksi, ihmisen koolonin epiteelisolujen viljelemiseen ja immortalisoimiseen sopiva seerumia sisältämätön viljelyalusta, ihmisen koolonin immortalisoitu epiteelisolulinja, menetelmä suolikanavan....

Country Status (14)

Country Link
US (3) US6194203B1 (de)
EP (1) EP0802257B1 (de)
JP (1) JP3931212B2 (de)
AT (1) ATE222598T1 (de)
AU (1) AU733913B2 (de)
CA (1) CA2202923C (de)
DE (1) DE69623109T2 (de)
DK (1) DK0802257T3 (de)
ES (1) ES2180689T3 (de)
FI (1) FI120352B (de)
NO (1) NO319494B1 (de)
NZ (1) NZ314614A (de)
PT (1) PT802257E (de)
RU (1) RU2220201C2 (de)

Families Citing this family (46)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2180689T3 (es) * 1996-04-19 2003-02-16 Nestle Sa Linea inmortalizada de celulas epiteliales del colon humano.
DE69636755T2 (de) 1996-12-24 2007-10-11 Société des Produits Nestlé S.A. Immortalisierte menschliche Epithelzell-Linie
US5960073A (en) * 1997-04-03 1999-09-28 Genesys Telecommunications Laboratories , Inc. Method and apparatus for providing an interactive home agent with access to call center functionality and resources
DE19755023C2 (de) * 1997-12-11 2000-03-09 Celanese Chem Europe Gmbh Katalysator und Verfahren zur Herstellung von Vinylacetat
DK1048725T3 (da) * 1999-04-27 2005-08-22 Transgene Sa Fremgangsmåde til fremstilling af pattedyrcellelinjer
EP1048724A1 (de) * 1999-04-27 2000-11-02 Transgene S.A. Humane Myoblastzellinien und deren Anwendungen
US7078232B2 (en) * 1999-08-19 2006-07-18 Artecel, Inc. Adipose tissue-derived adult stem or stromal cells for the repair of articular cartilage fractures and uses thereof
US6429013B1 (en) * 1999-08-19 2002-08-06 Artecel Science, Inc. Use of adipose tissue-derived stromal cells for chondrocyte differentiation and cartilage repair
US6416999B1 (en) * 2000-04-07 2002-07-09 Raven Biotechnologies, Inc. Human Müllerian duct-derived epithelial cells and methods of isolation and uses thereof
EP1360314B1 (de) * 2001-02-15 2009-01-14 Centocor, Inc. Chemisch definiertes medium für kultivierte säugerzellen
US20030215941A1 (en) * 2002-03-12 2003-11-20 Stewart Campbell Assay device that analyzes the absorption, metabolism, permeability and/or toxicity of a candidate compound
US7115563B2 (en) * 2002-05-29 2006-10-03 Insignion Holding Limited Composition and its therapeutic use
GB0212405D0 (en) * 2002-05-29 2002-07-10 Insignion Holdings Ltd Composition and its therapeutic use
BRPI0513549A (pt) * 2004-07-19 2008-05-06 Inst Rech Pour Le Developpment composições farmacêuticas para o tratamento de leishmaniose
US8273553B2 (en) * 2004-11-02 2012-09-25 Ares Trading S.A. Production of growth hormone in serum-free cell culture medium for mammalian cells
DE602005026548D1 (de) 2004-11-02 2011-04-07 Ares Trading Sa Serumfreies kulturmedium für säugerzellen
BRPI0520498B8 (pt) 2005-08-26 2021-05-25 Ares Trading Sa processo para fabricação de interferon beta humano recombinante glicosilado, e uso de um meio de cultura isento de soro
US8911964B2 (en) 2006-09-13 2014-12-16 Abbvie Inc. Fed-batch method of making human anti-TNF-alpha antibody
SG10201510384UA (en) 2006-09-13 2016-01-28 Abbvie Inc Cell culture improvements
CA2738499A1 (en) 2008-10-20 2010-04-29 Abbott Laboratories Viral inactivation during purification of antibodies
AU2009347206C1 (en) 2008-10-20 2016-12-08 Abbvie Inc. Isolation and purification of antibodies using Protein A affinity chromatography
EP2702077A2 (de) 2011-04-27 2014-03-05 AbbVie Inc. Verfahren zur steuerung des galactosylierungsprofil von rekombinant exprimierten proteinen
ES2627342T3 (es) * 2011-07-12 2017-07-27 Foodchek Systems, Inc. Medio de cultivo, método para cultivar Salmonella y E. coli y método para detectar Salmonella y E. coli
US9150645B2 (en) 2012-04-20 2015-10-06 Abbvie, Inc. Cell culture methods to reduce acidic species
US9067990B2 (en) 2013-03-14 2015-06-30 Abbvie, Inc. Protein purification using displacement chromatography
WO2013158273A1 (en) 2012-04-20 2013-10-24 Abbvie Inc. Methods to modulate c-terminal lysine variant distribution
US20130281355A1 (en) * 2012-04-24 2013-10-24 Genentech, Inc. Cell culture compositions and methods for polypeptide production
US9249182B2 (en) 2012-05-24 2016-02-02 Abbvie, Inc. Purification of antibodies using hydrophobic interaction chromatography
US9206390B2 (en) 2012-09-02 2015-12-08 Abbvie, Inc. Methods to control protein heterogeneity
US9512214B2 (en) 2012-09-02 2016-12-06 Abbvie, Inc. Methods to control protein heterogeneity
EP2767273A1 (de) 2013-02-15 2014-08-20 Universitätsklinikum Erlangen Todassoziierte Proteinkinasen, Hemmer und Aktivatoren für die Verwendung in pharmazeutischen Zusammensetzungen und vorhersagbare Medizin
CA2905010A1 (en) 2013-03-12 2014-09-18 Abbvie Inc. Human antibodies that bind human tnf-alpha and methods of preparing the same
WO2014159579A1 (en) 2013-03-14 2014-10-02 Abbvie Inc. MUTATED ANTI-TNFα ANTIBODIES AND METHODS OF THEIR USE
US9017687B1 (en) 2013-10-18 2015-04-28 Abbvie, Inc. Low acidic species compositions and methods for producing and using the same using displacement chromatography
WO2014151878A2 (en) 2013-03-14 2014-09-25 Abbvie Inc. Methods for modulating protein glycosylation profiles of recombinant protein therapeutics using monosaccharides and oligosacharides
EP3052640A2 (de) 2013-10-04 2016-08-10 AbbVie Inc. Verwendung von metallionen zur modulation von proteinglykosylierungsprofilen rekombinanter proteine
US8946395B1 (en) 2013-10-18 2015-02-03 Abbvie Inc. Purification of proteins using hydrophobic interaction chromatography
US9181337B2 (en) 2013-10-18 2015-11-10 Abbvie, Inc. Modulated lysine variant species compositions and methods for producing and using the same
US9085618B2 (en) 2013-10-18 2015-07-21 Abbvie, Inc. Low acidic species compositions and methods for producing and using the same
WO2015073884A2 (en) 2013-11-15 2015-05-21 Abbvie, Inc. Glycoengineered binding protein compositions
EP3352586A4 (de) 2015-09-21 2019-05-15 The Board Of Trustees Of The Leland Stanford Junior University Ernährungsbehandlung bei krebserkrankungen
US11060061B2 (en) * 2017-08-09 2021-07-13 Mandom Corporation Immortalized sweat gland myoepithelial cell
WO2019118519A1 (en) 2017-12-11 2019-06-20 Filtricine, Inc. Compositions, methods, kits and systems for cancer treatment and metabolic intervention therapy
CN111172114B (zh) * 2019-12-10 2021-11-30 上海中医药大学附属岳阳中西医结合医院 一种人源化肠癌前病变永生化上皮细胞系、构建方法及其应用
CN114891722A (zh) * 2022-05-13 2022-08-12 广东省农业科学院动物卫生研究所 禽肠道上皮细胞及其制备方法和应用
CN116083342A (zh) * 2023-01-16 2023-05-09 细新(上海)医疗科技有限公司 一种原代上皮细胞的培养体系和应用

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4229531A (en) * 1978-12-29 1980-10-21 Monsanto Company Production of tumor angiogenesis factor by cell culture
DE3711699A1 (de) * 1987-04-07 1988-11-10 Fraunhofer Ges Forschung Medium zur kultivierung und proliferation von epithelialen zelltypen
US4885238A (en) * 1987-10-30 1989-12-05 The United States Of America As Represented By The Department Of Health And Human Services Immortalized human bronchial epitherial mesothelial cell lines
AU2921289A (en) * 1987-12-09 1989-07-19 Invitron Corporation Human cell life extension
US5093259A (en) * 1988-07-07 1992-03-03 Oak Ridge Associated Universities, Inc. Continuous cell-line tamarin adenocarcinoma of the colon
US5529920A (en) * 1988-12-14 1996-06-25 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Human liver epithelial cell line and culture media therefor
US5665589A (en) * 1988-12-14 1997-09-09 The United States Of America As Represented By The Department Of Health And Human Services Human liver epithelial cell lines
US5376542A (en) 1992-04-27 1994-12-27 Georgetown University Method for producing immortalized cell lines using human papilluma virus genes
DE69219768T2 (de) 1992-07-06 1997-08-28 Societe Des Produits Nestle S.A., Vevey Milchbakterien
US5462870A (en) * 1993-04-23 1995-10-31 Wayne State University Human diploid salivary gland epithelial cell lines
US5672498A (en) * 1993-12-28 1997-09-30 The Gillete Company Human corneal epithelial cell lines with extended lifespan
US5610043A (en) * 1994-04-28 1997-03-11 The United States Of America As Represented By The Department Of Health And Human Services Human prostatic cell lines immortalized by adenovirus 12-simian virus 40 (AD12/SV40) hybrid virus
ES2180689T3 (es) * 1996-04-19 2003-02-16 Nestle Sa Linea inmortalizada de celulas epiteliales del colon humano.

Also Published As

Publication number Publication date
NO971757D0 (no) 1997-04-17
US6395542B1 (en) 2002-05-28
AU1893397A (en) 1997-10-23
RU2220201C2 (ru) 2003-12-27
ES2180689T3 (es) 2003-02-16
FI971628A (fi) 1997-10-20
FI971628A0 (fi) 1997-04-17
DE69623109T2 (de) 2002-12-12
PT802257E (pt) 2003-01-31
ATE222598T1 (de) 2002-09-15
JPH1028580A (ja) 1998-02-03
DK0802257T3 (da) 2002-10-28
CA2202923C (en) 2008-06-10
JP3931212B2 (ja) 2007-06-13
DE69623109D1 (de) 2002-09-26
NO319494B1 (no) 2005-08-22
EP0802257A1 (de) 1997-10-22
NZ314614A (en) 1999-04-29
US6399381B1 (en) 2002-06-04
NO971757L (no) 1997-10-20
AU733913B2 (en) 2001-05-31
EP0802257B1 (de) 2002-08-21
US6194203B1 (en) 2001-02-27
CA2202923A1 (en) 1997-10-19

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