DK0802257T3 - Udødeliggjort cellelinie fra epitelceller i human colon - Google Patents

Udødeliggjort cellelinie fra epitelceller i human colon

Info

Publication number
DK0802257T3
DK0802257T3 DK96201064T DK96201064T DK0802257T3 DK 0802257 T3 DK0802257 T3 DK 0802257T3 DK 96201064 T DK96201064 T DK 96201064T DK 96201064 T DK96201064 T DK 96201064T DK 0802257 T3 DK0802257 T3 DK 0802257T3
Authority
DK
Denmark
Prior art keywords
human colon
epithelial cells
colon epithelial
cells
cell line
Prior art date
Application number
DK96201064T
Other languages
Danish (da)
English (en)
Inventor
Stephanie Blum
Andrea Pfeifer
Yvonne Troumvoukis
Original Assignee
Nestle Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nestle Sa filed Critical Nestle Sa
Application granted granted Critical
Publication of DK0802257T3 publication Critical patent/DK0802257T3/da

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0679Cells of the gastro-intestinal tract
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00Specific components of cell culture medium
    • C12N2500/05Inorganic components
    • C12N2500/10Metals; Metal chelators
    • C12N2500/20Transition metals
    • C12N2500/24Iron; Fe chelators; Transferrin
    • C12N2500/25Insulin-transferrin; Insulin-transferrin-selenium
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00Specific components of cell culture medium
    • C12N2500/30Organic components
    • C12N2500/38Vitamins
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00Specific components of cell culture medium
    • C12N2500/90Serum-free medium, which may still contain naturally-sourced components
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10Growth factors
    • C12N2501/11Epidermal growth factor [EGF]
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/30Hormones
    • C12N2501/38Hormones with nuclear receptors
    • C12N2501/39Steroid hormones
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/30Hormones
    • C12N2501/38Hormones with nuclear receptors
    • C12N2501/395Thyroid hormones
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2503/00Use of cells in diagnostics
    • C12N2503/02Drug screening
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2510/00Genetically modified cells
    • C12N2510/04Immortalised cells

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Prostheses (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DK96201064T 1996-04-19 1996-04-19 Udødeliggjort cellelinie fra epitelceller i human colon DK0802257T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP96201064A EP0802257B1 (de) 1996-04-19 1996-04-19 Menschliche immortalisierte Colon-Epithelialzellen

Publications (1)

Publication Number Publication Date
DK0802257T3 true DK0802257T3 (da) 2002-10-28

Family

ID=8223895

Family Applications (1)

Application Number Title Priority Date Filing Date
DK96201064T DK0802257T3 (da) 1996-04-19 1996-04-19 Udødeliggjort cellelinie fra epitelceller i human colon

Country Status (14)

Country Link
US (3) US6194203B1 (de)
EP (1) EP0802257B1 (de)
JP (1) JP3931212B2 (de)
AT (1) ATE222598T1 (de)
AU (1) AU733913B2 (de)
CA (1) CA2202923C (de)
DE (1) DE69623109T2 (de)
DK (1) DK0802257T3 (de)
ES (1) ES2180689T3 (de)
FI (1) FI120352B (de)
NO (1) NO319494B1 (de)
NZ (1) NZ314614A (de)
PT (1) PT802257E (de)
RU (1) RU2220201C2 (de)

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DE19755023C2 (de) * 1997-12-11 2000-03-09 Celanese Chem Europe Gmbh Katalysator und Verfahren zur Herstellung von Vinylacetat
DK1048725T3 (da) * 1999-04-27 2005-08-22 Transgene Sa Fremgangsmåde til fremstilling af pattedyrcellelinjer
EP1048724A1 (de) * 1999-04-27 2000-11-02 Transgene S.A. Humane Myoblastzellinien und deren Anwendungen
US6429013B1 (en) * 1999-08-19 2002-08-06 Artecel Science, Inc. Use of adipose tissue-derived stromal cells for chondrocyte differentiation and cartilage repair
US7078232B2 (en) * 1999-08-19 2006-07-18 Artecel, Inc. Adipose tissue-derived adult stem or stromal cells for the repair of articular cartilage fractures and uses thereof
US6416999B1 (en) 2000-04-07 2002-07-09 Raven Biotechnologies, Inc. Human Müllerian duct-derived epithelial cells and methods of isolation and uses thereof
US6900056B2 (en) * 2001-02-15 2005-05-31 Centocor, Inc. Chemically defined medium for cultured mammalian cells
US20030215941A1 (en) * 2002-03-12 2003-11-20 Stewart Campbell Assay device that analyzes the absorption, metabolism, permeability and/or toxicity of a candidate compound
GB0212405D0 (en) * 2002-05-29 2002-07-10 Insignion Holdings Ltd Composition and its therapeutic use
US7115563B2 (en) * 2002-05-29 2006-10-03 Insignion Holding Limited Composition and its therapeutic use
ATE447953T1 (de) * 2004-07-19 2009-11-15 Inst Rech Developpement Ird Pharmazeutische zusammensetzungen zur behandlung von leishmaniasis
US8273553B2 (en) * 2004-11-02 2012-09-25 Ares Trading S.A. Production of growth hormone in serum-free cell culture medium for mammalian cells
ZA200702434B (en) 2004-11-02 2008-08-27 Ares Trading Sa Serum-free cell culture medium for mammalian cells
EP2390263A1 (de) 2005-08-26 2011-11-30 Ares Trading S.A. Verfahren zur Herstellung von glycosyliertem Interferon beta
MY185872A (en) 2006-09-13 2021-06-14 Abbvie Inc Cell culture improvements
US8911964B2 (en) 2006-09-13 2014-12-16 Abbvie Inc. Fed-batch method of making human anti-TNF-alpha antibody
TW201028433A (en) 2008-10-20 2010-08-01 Abbott Lab Viral inactivation during purification of antibodies
WO2010141039A1 (en) 2008-10-20 2010-12-09 Abbott Laboratories Isolation and purification of antibodies using protein a affinity chromatography
EP2702077A2 (de) 2011-04-27 2014-03-05 AbbVie Inc. Verfahren zur steuerung des galactosylierungsprofil von rekombinant exprimierten proteinen
GB2497249B (en) * 2011-07-12 2016-12-28 Foodchek Systems Inc Culture medium,method for culturing salmonella and e.coli and method for detecting salmonella and e.coli
US9150645B2 (en) 2012-04-20 2015-10-06 Abbvie, Inc. Cell culture methods to reduce acidic species
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US20130281355A1 (en) * 2012-04-24 2013-10-24 Genentech, Inc. Cell culture compositions and methods for polypeptide production
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US9206390B2 (en) 2012-09-02 2015-12-08 Abbvie, Inc. Methods to control protein heterogeneity
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EP2767273A1 (de) 2013-02-15 2014-08-20 Universitätsklinikum Erlangen Todassoziierte Proteinkinasen, Hemmer und Aktivatoren für die Verwendung in pharmazeutischen Zusammensetzungen und vorhersagbare Medizin
WO2014143205A1 (en) 2013-03-12 2014-09-18 Abbvie Inc. Human antibodies that bind human tnf-alpha and methods of preparing the same
US9499614B2 (en) 2013-03-14 2016-11-22 Abbvie Inc. Methods for modulating protein glycosylation profiles of recombinant protein therapeutics using monosaccharides and oligosaccharides
US9017687B1 (en) 2013-10-18 2015-04-28 Abbvie, Inc. Low acidic species compositions and methods for producing and using the same using displacement chromatography
US8921526B2 (en) 2013-03-14 2014-12-30 Abbvie, Inc. Mutated anti-TNFα antibodies and methods of their use
US9598667B2 (en) 2013-10-04 2017-03-21 Abbvie Inc. Use of metal ions for modulation of protein glycosylation profiles of recombinant proteins
US9181337B2 (en) 2013-10-18 2015-11-10 Abbvie, Inc. Modulated lysine variant species compositions and methods for producing and using the same
US9085618B2 (en) 2013-10-18 2015-07-21 Abbvie, Inc. Low acidic species compositions and methods for producing and using the same
US8946395B1 (en) 2013-10-18 2015-02-03 Abbvie Inc. Purification of proteins using hydrophobic interaction chromatography
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EP3352586A4 (de) 2015-09-21 2019-05-15 The Board Of Trustees Of The Leland Stanford Junior University Ernährungsbehandlung bei krebserkrankungen
US11060061B2 (en) * 2017-08-09 2021-07-13 Mandom Corporation Immortalized sweat gland myoepithelial cell
EP3723772A4 (de) 2017-12-11 2021-09-08 Filtricine, Inc. Zusammensetzungen, verfahren, kits und systeme zur krebsbehandlung und stoffwechselinterventionstherapie
CN111172114B (zh) * 2019-12-10 2021-11-30 上海中医药大学附属岳阳中西医结合医院 一种人源化肠癌前病变永生化上皮细胞系、构建方法及其应用
CN114891722A (zh) * 2022-05-13 2022-08-12 广东省农业科学院动物卫生研究所 禽肠道上皮细胞及其制备方法和应用
CN116083342A (zh) * 2023-01-16 2023-05-09 细新(上海)医疗科技有限公司 一种原代上皮细胞的培养体系和应用

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Also Published As

Publication number Publication date
AU1893397A (en) 1997-10-23
NZ314614A (en) 1999-04-29
CA2202923C (en) 2008-06-10
EP0802257B1 (de) 2002-08-21
JPH1028580A (ja) 1998-02-03
CA2202923A1 (en) 1997-10-19
NO319494B1 (no) 2005-08-22
FI971628A0 (fi) 1997-04-17
FI120352B (fi) 2009-09-30
FI971628A (fi) 1997-10-20
DE69623109D1 (de) 2002-09-26
NO971757D0 (no) 1997-04-17
RU2220201C2 (ru) 2003-12-27
ES2180689T3 (es) 2003-02-16
EP0802257A1 (de) 1997-10-22
US6194203B1 (en) 2001-02-27
NO971757L (no) 1997-10-20
JP3931212B2 (ja) 2007-06-13
ATE222598T1 (de) 2002-09-15
US6395542B1 (en) 2002-05-28
PT802257E (pt) 2003-01-31
US6399381B1 (en) 2002-06-04
DE69623109T2 (de) 2002-12-12
AU733913B2 (en) 2001-05-31

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