HK1205505A1 - A method of preparing a highly pure potassium salt of azilsartan medoxomil - Google Patents
A method of preparing a highly pure potassium salt of azilsartan medoxomil Download PDFInfo
- Publication number
- HK1205505A1 HK1205505A1 HK15106026.8A HK15106026A HK1205505A1 HK 1205505 A1 HK1205505 A1 HK 1205505A1 HK 15106026 A HK15106026 A HK 15106026A HK 1205505 A1 HK1205505 A1 HK 1205505A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- azilsartan medoxomil
- solvate
- dimethylacetamide
- potassium salt
- methylpyrrolidone
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Peptides Or Proteins (AREA)
- Epidemiology (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CZPV2012-663 | 2012-09-26 | ||
| CZ2012-663A CZ305318B6 (cs) | 2012-09-26 | 2012-09-26 | Způsob přípravy vysoce čisté draselné soli azilsartanu medoxomilu |
| PCT/CZ2013/000114 WO2014048404A1 (en) | 2012-09-26 | 2013-09-25 | A method of preparing a highly pure potassium salt of azilsartan medoxomil |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HK1205505A1 true HK1205505A1 (en) | 2015-12-18 |
Family
ID=66624776
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HK15106026.8A HK1205505A1 (en) | 2012-09-26 | 2013-09-25 | A method of preparing a highly pure potassium salt of azilsartan medoxomil |
Country Status (12)
| Country | Link |
|---|---|
| EP (1) | EP2900662A1 (cs) |
| JP (1) | JP2015532267A (cs) |
| KR (1) | KR20150060733A (cs) |
| CN (1) | CN104662019A (cs) |
| BR (1) | BR112015006572A2 (cs) |
| CZ (1) | CZ305318B6 (cs) |
| EA (1) | EA028171B1 (cs) |
| HK (1) | HK1205505A1 (cs) |
| IL (1) | IL237884A0 (cs) |
| MX (1) | MX2015003209A (cs) |
| UA (1) | UA113668C2 (cs) |
| WO (1) | WO2014048404A1 (cs) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CZ2014702A3 (cs) * | 2014-10-15 | 2016-04-27 | Zentiva, K.S. | Způsob přípravy vysoce čistého azilsartanu |
| CN105753854A (zh) * | 2014-12-16 | 2016-07-13 | 重庆朗天制药有限公司 | 一种阿齐沙坦酯钾盐的新制备方法 |
| CN109071519A (zh) * | 2016-01-28 | 2018-12-21 | 株式会社德山 | 阿齐沙坦及其制造方法 |
| CN108727356A (zh) * | 2018-06-28 | 2018-11-02 | 江苏新瑞药业有限公司 | 一种奥美沙坦酯碱金属盐的合成方法 |
| CN115894472B (zh) * | 2022-12-14 | 2025-08-19 | 仁合益康集团有限公司 | 一种高纯度阿齐沙坦酯钾盐的制备方法 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7157584B2 (en) | 2004-02-25 | 2007-01-02 | Takeda Pharmaceutical Company Limited | Benzimidazole derivative and use thereof |
| WO2012090043A1 (en) * | 2010-12-29 | 2012-07-05 | Jubilant Life Sciences Limited | Novel solid state forms of azilsartan medoxomil and preparation thereof |
| JP2014505097A (ja) * | 2011-02-08 | 2014-02-27 | ジュビラント ライフ サイエンセズ リミテッド | アジルサルタンメドキソミルの改良製造方法 |
| WO2013042067A1 (en) * | 2011-09-20 | 2013-03-28 | Ranbaxy Laboratories Limited | Process for the preparation of potassium salt of azilsartan medoxomil |
| CN104039779B (zh) * | 2012-01-14 | 2016-08-24 | 广东东阳光药业有限公司 | 阿齐沙坦酯钾的晶型及其制备方法及其用途 |
| CZ2012274A3 (cs) * | 2012-04-19 | 2013-10-30 | Zentiva, K.S. | Zpusob prípravy vysoce cisté draselné soli azilsartanu medoxomilu |
-
2012
- 2012-09-26 CZ CZ2012-663A patent/CZ305318B6/cs not_active IP Right Cessation
-
2013
- 2013-09-25 JP JP2015533448A patent/JP2015532267A/ja active Pending
- 2013-09-25 CN CN201380050044.9A patent/CN104662019A/zh active Pending
- 2013-09-25 UA UAA201503960A patent/UA113668C2/uk unknown
- 2013-09-25 MX MX2015003209A patent/MX2015003209A/es unknown
- 2013-09-25 EA EA201590657A patent/EA028171B1/ru not_active IP Right Cessation
- 2013-09-25 KR KR1020157007800A patent/KR20150060733A/ko not_active Withdrawn
- 2013-09-25 EP EP13779507.6A patent/EP2900662A1/en not_active Withdrawn
- 2013-09-25 HK HK15106026.8A patent/HK1205505A1/xx unknown
- 2013-09-25 BR BR112015006572A patent/BR112015006572A2/pt not_active IP Right Cessation
- 2013-09-25 WO PCT/CZ2013/000114 patent/WO2014048404A1/en active Application Filing
-
2015
- 2015-03-22 IL IL237884A patent/IL237884A0/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| UA113668C2 (uk) | 2017-02-27 |
| CN104662019A (zh) | 2015-05-27 |
| CZ305318B6 (cs) | 2015-07-29 |
| JP2015532267A (ja) | 2015-11-09 |
| EA201590657A1 (ru) | 2015-08-31 |
| EA028171B1 (ru) | 2017-10-31 |
| EP2900662A1 (en) | 2015-08-05 |
| KR20150060733A (ko) | 2015-06-03 |
| WO2014048404A1 (en) | 2014-04-03 |
| IL237884A0 (en) | 2015-05-31 |
| BR112015006572A2 (pt) | 2017-07-04 |
| CZ2012663A3 (cs) | 2014-04-02 |
| MX2015003209A (es) | 2015-07-14 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| EP2673274B1 (en) | An improved process for the preparation of azilsartan medoxomil | |
| JP2013532164A (ja) | トロンビン特異的インヒビターを調製する方法 | |
| HK1205505A1 (en) | A method of preparing a highly pure potassium salt of azilsartan medoxomil | |
| WO2013105106A1 (en) | An improved process for the preparation of etoricoxib and polymorphs thereof | |
| US9624207B2 (en) | Polymorphs of azilsartan medoxomil | |
| JP2014524887A (ja) | アジルサルタンの改善された製造方法 | |
| WO2018008219A1 (ja) | アジルサルタン中間体、アジルサルタン、及びこれらの製造方法 | |
| JP2013531004A (ja) | トロンビン特異的インヒビターの調製のための中間体及び方法 | |
| EP3024821A1 (en) | Process for the preparation of perampanel | |
| EP2872499A1 (en) | Process for the preparation of intermediates for the synthesis of dabigatran etexilate, and crystalline forms of said intermediates | |
| EP3589606B1 (en) | Transition metal-catalyzed protodecarboxylation of alpha-halo-acrylic acid derivatives | |
| TW201625582A (zh) | 製備吡蟲啉（ｉｍｉｄａｃｌｏｐｒｉｄ）多晶型的方法 | |
| KR101316653B1 (ko) | 헤테로고리 화합물의 제조방법 | |
| CZ2012274A3 (cs) | Zpusob prípravy vysoce cisté draselné soli azilsartanu medoxomilu | |
| US20100113783A1 (en) | Process for the preparation of crystals of prulifloxacin | |
| EP3207040A1 (en) | A process for preparing highly pure azilsartan | |
| JP2013508418A (ja) | １−（４−（（１ｒ，２ｓ，３ｒ）−１，２，３，４−テトラヒドロキシブチル）−１ｈ−イミダゾール−２−イル）エタノンを調製する方法 | |
| JP2018076258A (ja) | アジルサルタンアルキルエステル、アジルサルタンメチルエステルの製造方法、及びアジルサルタンの製造方法 | |
| JP2018197206A (ja) | アジルサルタン合成中間体の製造方法 | |
| US20150291574A1 (en) | Novel polymorphs of azilsartan | |
| JP2010100562A (ja) | アムロジピン製造中間体の精製方法 |