HK1201199A1 - Methods of using fgf19 modulators - Google Patents

Methods of using fgf19 modulators Download PDF

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Publication number
HK1201199A1
HK1201199A1 HK15101805.6A HK15101805A HK1201199A1 HK 1201199 A1 HK1201199 A1 HK 1201199A1 HK 15101805 A HK15101805 A HK 15101805A HK 1201199 A1 HK1201199 A1 HK 1201199A1
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HK
Hong Kong
Prior art keywords
fgf19
individual
bile acid
antibody
level
Prior art date
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HK15101805.6A
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English (en)
Chinese (zh)
Inventor
Rama PAI
Donna M. DAMBACH
Dorothy French
Veronique V. LAURIAULT
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霍夫曼-拉罗奇有限公司
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Publication of HK1201199A1 publication Critical patent/HK1201199A1/xx

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/22Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Physics & Mathematics (AREA)
  • Endocrinology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Steroid Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
HK15101805.6A 2012-01-18 2013-01-18 Methods of using fgf19 modulators HK1201199A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261587885P 2012-01-18 2012-01-18
US61/587,885 2012-01-18
PCT/US2013/022103 WO2013109856A2 (en) 2012-01-18 2013-01-18 Methods of using fgf19 modulators

Publications (1)

Publication Number Publication Date
HK1201199A1 true HK1201199A1 (en) 2015-08-28

Family

ID=47604273

Family Applications (1)

Application Number Title Priority Date Filing Date
HK15101805.6A HK1201199A1 (en) 2012-01-18 2013-01-18 Methods of using fgf19 modulators

Country Status (11)

Country Link
US (2) US20130183294A1 (enExample)
EP (1) EP2804630B1 (enExample)
JP (2) JP2015506944A (enExample)
KR (1) KR20140119114A (enExample)
CN (1) CN104168920A (enExample)
BR (1) BR112014017626A2 (enExample)
CA (1) CA2862424A1 (enExample)
HK (1) HK1201199A1 (enExample)
MX (1) MX2014008699A (enExample)
RU (1) RU2014133547A (enExample)
WO (1) WO2013109856A2 (enExample)

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CN110354128A (zh) 2013-10-18 2019-10-22 卫材R&D管理有限公司 嘧啶fgfr4抑制剂
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US10456449B2 (en) 2014-06-16 2019-10-29 Ngm Biopharmaceuticals, Inc. Methods and uses for modulating bile acid homeostasis and treatment of bile acid disorders and diseases
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CN107108711B (zh) 2014-10-23 2021-11-23 恩格姆生物制药公司 包含肽变异体的药物组合物及其使用方法
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EP3503882A4 (en) 2016-08-26 2020-07-29 NGM Biopharmaceuticals, Inc. METHOD FOR TREATING FIBROBLAST GROWTH FACTOR-19-MEDIATED CARCINOMAS AND TUMORS
CN109709220B (zh) * 2017-10-25 2021-09-17 中国科学院大连化学物理研究所 一种用于诊断膀胱癌的联合标志物及试剂盒和应用
CN109722480B (zh) * 2018-05-17 2022-04-26 上海交通大学 一种非小细胞肺癌检测试剂盒及其应用
JP7193114B2 (ja) * 2018-08-29 2022-12-20 学校法人同志社 胆汁酸サイクルの観察方法
CN110558256B (zh) * 2019-10-09 2020-06-26 中国水产科学研究院黄海水产研究所 一种程序化调控红鳍东方鲀胆汁酸分泌的营养学方法
CN114106161A (zh) * 2020-08-28 2022-03-01 安源医药科技(上海)有限公司 针对SARS-CoV-2冠状病毒S蛋白的抗体及其用途

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EP2804630A2 (en) 2014-11-26
CA2862424A1 (en) 2013-07-25
US20170342488A1 (en) 2017-11-30
WO2013109856A3 (en) 2013-11-14
WO2013109856A2 (en) 2013-07-25
BR112014017626A2 (pt) 2018-05-22
EP2804630B1 (en) 2017-10-18
RU2014133547A (ru) 2016-03-10
MX2014008699A (es) 2014-11-21
JP2015506944A (ja) 2015-03-05
CN104168920A (zh) 2014-11-26
KR20140119114A (ko) 2014-10-08
US20130183294A1 (en) 2013-07-18

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