HK1201067A1 - Sialic acid analogs - Google Patents

Sialic acid analogs Download PDF

Info

Publication number
HK1201067A1
HK1201067A1 HK15101526.4A HK15101526A HK1201067A1 HK 1201067 A1 HK1201067 A1 HK 1201067A1 HK 15101526 A HK15101526 A HK 15101526A HK 1201067 A1 HK1201067 A1 HK 1201067A1
Authority
HK
Hong Kong
Prior art keywords
sialic acid
acid analogs
analogs
treatment
present
Prior art date
Application number
HK15101526.4A
Other languages
English (en)
Chinese (zh)
Inventor
埃米爾.卡吉斯
埃米尔.卡吉斯
史蒂文.賈格爾
史蒂文.贾格尔
何釗
何钊
Original Assignee
罕见病药物研发公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 罕见病药物研发公司 filed Critical 罕见病药物研发公司
Publication of HK1201067A1 publication Critical patent/HK1201067A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H7/00—Compounds containing non-saccharide radicals linked to saccharide radicals by a carbon-to-carbon bond
    • C07H7/02—Acyclic radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/08—Bridged systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
    • C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
    • C07H13/04—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals attached to acyclic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
    • C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
    • C07H13/10—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals directly attached to heterocyclic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H7/00—Compounds containing non-saccharide radicals linked to saccharide radicals by a carbon-to-carbon bond
    • C07H7/02—Acyclic radicals
    • C07H7/027—Keto-aldonic acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Neurology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Medicinal Preparation (AREA)
HK15101526.4A 2011-10-24 2012-10-24 Sialic acid analogs HK1201067A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161550610P 2011-10-24 2011-10-24
US61/550,610 2011-10-24
PCT/US2012/061737 WO2013063149A1 (en) 2011-10-24 2012-10-24 Sialic acid analogs

Publications (1)

Publication Number Publication Date
HK1201067A1 true HK1201067A1 (en) 2015-08-21

Family

ID=48168447

Family Applications (1)

Application Number Title Priority Date Filing Date
HK15101526.4A HK1201067A1 (en) 2011-10-24 2012-10-24 Sialic acid analogs

Country Status (13)

Country Link
US (5) US8840926B2 (enExample)
EP (1) EP2771348B1 (enExample)
JP (1) JP6196224B2 (enExample)
KR (1) KR102049214B1 (enExample)
CN (1) CN103974965B (enExample)
AU (1) AU2012328874B2 (enExample)
BR (1) BR112014009760B1 (enExample)
CA (1) CA2849114C (enExample)
ES (1) ES2807890T3 (enExample)
HK (1) HK1201067A1 (enExample)
IL (1) IL231714B (enExample)
MX (1) MX347541B (enExample)
WO (1) WO2013063149A1 (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9241896B2 (en) 2008-12-19 2016-01-26 Ultragenyx Pharmaceutical Inc. Methods and formulations for treating sialic acid deficiencies
KR20140003380A (ko) 2010-07-13 2014-01-09 울트라제닉스 파마수티컬 인코포레이티드 시알산 결함 치료용 방법들 및 제형들
AU2012328874B2 (en) 2011-10-24 2017-08-31 Ultragenyx Pharmaceutical Inc. Sialic acid analogs
CN104271125A (zh) * 2012-01-18 2015-01-07 奥特吉尼克斯制药公司 用于治疗唾液酸缺乏的方法和制剂
AR106025A1 (es) 2015-09-14 2017-12-06 Ultragenyx Pharmaceutical Inc Formas cristalinas de ácido siálico o una sal o solvato de este
EP4665860A1 (en) * 2023-02-17 2025-12-24 Ultragenyx Pharmaceutical Inc. Crystalline forms of sialic acid derivatives and methods for their use

Family Cites Families (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6168418A (ja) 1984-09-11 1986-04-08 Kanto Ishi Pharma Co Ltd 去痰薬
JPS63139193A (ja) * 1986-11-28 1988-06-10 Mect Corp シアル酸誘導体1,7−ラクトン
US6156544A (en) 1993-06-09 2000-12-05 Glaxo Group Limited Process for the preparation of N-acetylneuraminic acid
WO1996031237A2 (en) 1995-04-04 1996-10-10 Wound Healing Of Oklahoma Cancer treatment by photodynamic therapy, in combination with an immunoadjuvant
US5624677A (en) 1995-06-13 1997-04-29 Pentech Pharmaceuticals, Inc. Controlled release of drugs delivered by sublingual or buccal administration
WO1999052931A1 (fr) 1998-04-10 1999-10-21 Mitsubishi Chemical Corporation Dispersion solide contenant un derive d'acide sialique
KR20030006721A (ko) 2001-07-14 2003-01-23 삼성전자 주식회사 리소그라피 시스템 및 이를 이용한 레티클 표면의 파티클제거방법
ES2363205T3 (es) 2002-06-21 2011-07-26 Novo Nordisk Health Care Ag Glicoformas del factor vii pegilado.
US7238677B2 (en) 2003-03-28 2007-07-03 Kimberly-Clark Worldwide, Inc. Prevention of urogenital infections
WO2005056708A2 (en) * 2003-12-09 2005-06-23 Spherics, Inc. Bioadhesive polymers with catechol functionality
NZ561116A (en) 2005-03-03 2010-02-26 Mannatech Inc Methods and compositions for modified release of nutritional supplements
WO2007103286A2 (en) * 2006-03-02 2007-09-13 Spherics, Inc. Rate-controlled bioadhesive oral dosage formulations
WO2008027557A2 (en) * 2006-08-31 2008-03-06 Spherics, Inc. Topiramate compositions and methods of enhancing its bioavailability
CA2903133C (en) 2007-05-31 2021-10-19 Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services National Institutes Of Health N-acetyl mannosamine or derivatives thereof for use in treating a kidney disorder in a mammal
US20090081249A1 (en) 2007-08-27 2009-03-26 Massachusetts Institute Of Technology Bi-Functional Polymer-Attached Inhibitors of Influenza Virus
CN102316730A (zh) 2008-05-09 2012-01-11 天雅瑞药业有限公司 用于减轻全身性炎症和/或血管炎症的n-乙酰半胱氨酸(nac)的控释
KR101116864B1 (ko) 2008-08-01 2012-02-29 주식회사 베네비오 고지혈증, 지방간 또는 비만의 예방 또는 치료용 조성물
US20100160363A1 (en) 2008-12-19 2010-06-24 Aaipharma Services Corp. Extended-release pharmaceutical formulations
US9241896B2 (en) 2008-12-19 2016-01-26 Ultragenyx Pharmaceutical Inc. Methods and formulations for treating sialic acid deficiencies
US20100159001A1 (en) 2008-12-19 2010-06-24 Cardinal John R Extended-Release Pharmaceutical Formulations
JP5626734B2 (ja) * 2009-05-15 2014-11-19 公益財団法人ヒューマンサイエンス振興財団 Gneタンパク質の機能低下に起因する疾患の治療用医薬剤、食品組成物
KR20140003380A (ko) 2010-07-13 2014-01-09 울트라제닉스 파마수티컬 인코포레이티드 시알산 결함 치료용 방법들 및 제형들
AU2012328874B2 (en) 2011-10-24 2017-08-31 Ultragenyx Pharmaceutical Inc. Sialic acid analogs
CN104271125A (zh) 2012-01-18 2015-01-07 奥特吉尼克斯制药公司 用于治疗唾液酸缺乏的方法和制剂
ES2777838T3 (es) 2015-01-28 2020-08-06 Kyowa Hakko Bio Co Ltd Cristal de anhidrato de N-acetilneuraminato de amonio y procedimiento para producir el mismo
AR106025A1 (es) 2015-09-14 2017-12-06 Ultragenyx Pharmaceutical Inc Formas cristalinas de ácido siálico o una sal o solvato de este

Also Published As

Publication number Publication date
KR20140084277A (ko) 2014-07-04
JP6196224B2 (ja) 2017-09-13
CN103974965B (zh) 2019-09-24
US9221858B2 (en) 2015-12-29
KR102049214B1 (ko) 2019-11-28
US8840926B2 (en) 2014-09-23
IL231714A0 (en) 2014-05-28
BR112014009760B1 (pt) 2022-11-29
EP2771348B1 (en) 2020-05-20
BR112014009760A2 (pt) 2017-04-18
US20200131215A1 (en) 2020-04-30
CN103974965A (zh) 2014-08-06
US10889607B2 (en) 2021-01-12
US10065981B2 (en) 2018-09-04
BR112014009760A8 (pt) 2018-01-16
CA2849114A1 (en) 2013-05-02
US20190127409A1 (en) 2019-05-02
ES2807890T3 (es) 2021-02-24
WO2013063149A1 (en) 2013-05-02
US20150038693A1 (en) 2015-02-05
CA2849114C (en) 2020-12-15
EP2771348A4 (en) 2015-09-09
AU2012328874B2 (en) 2017-08-31
MX2014004928A (es) 2014-11-10
IL231714B (en) 2018-10-31
US10457701B2 (en) 2019-10-29
JP2014530882A (ja) 2014-11-20
MX347541B (es) 2017-04-28
EP2771348A1 (en) 2014-09-03
US20130122094A1 (en) 2013-05-16
AU2012328874A1 (en) 2014-04-10
US20160297846A1 (en) 2016-10-13

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