ES2807890T3 - Análogos de ácido siálico - Google Patents
Análogos de ácido siálico Download PDFInfo
- Publication number
- ES2807890T3 ES2807890T3 ES12843460T ES12843460T ES2807890T3 ES 2807890 T3 ES2807890 T3 ES 2807890T3 ES 12843460 T ES12843460 T ES 12843460T ES 12843460 T ES12843460 T ES 12843460T ES 2807890 T3 ES2807890 T3 ES 2807890T3
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- UYWQUFXKFGHYNT-UHFFFAOYSA-N phenylmethyl ester of formic acid Chemical group O=COCC1=CC=CC=C1 UYWQUFXKFGHYNT-UHFFFAOYSA-N 0.000 description 1
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- 102000020233 phosphotransferase Human genes 0.000 description 1
- LFSXCDWNBUNEEM-UHFFFAOYSA-N phthalazine Chemical compound C1=NN=CC2=CC=CC=C21 LFSXCDWNBUNEEM-UHFFFAOYSA-N 0.000 description 1
- IUGYQRQAERSCNH-UHFFFAOYSA-N pivalic acid Chemical compound CC(C)(C)C(O)=O IUGYQRQAERSCNH-UHFFFAOYSA-N 0.000 description 1
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- 108090000765 processed proteins & peptides Proteins 0.000 description 1
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- CPNGPNLZQNNVQM-UHFFFAOYSA-N pteridine Chemical compound N1=CN=CC2=NC=CN=C21 CPNGPNLZQNNVQM-UHFFFAOYSA-N 0.000 description 1
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- IUVKMZGDUIUOCP-BTNSXGMBSA-N quinbolone Chemical compound O([C@H]1CC[C@H]2[C@H]3[C@@H]([C@]4(C=CC(=O)C=C4CC3)C)CC[C@@]21C)C1=CCCC1 IUVKMZGDUIUOCP-BTNSXGMBSA-N 0.000 description 1
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- 229910052708 sodium Inorganic materials 0.000 description 1
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- 229940005550 sodium alginate Drugs 0.000 description 1
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H7/00—Compounds containing non-saccharide radicals linked to saccharide radicals by a carbon-to-carbon bond
- C07H7/02—Acyclic radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
- C07D493/08—Bridged systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
- C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
- C07H13/04—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals attached to acyclic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
- C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
- C07H13/10—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals directly attached to heterocyclic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H7/00—Compounds containing non-saccharide radicals linked to saccharide radicals by a carbon-to-carbon bond
- C07H7/02—Acyclic radicals
- C07H7/027—Keto-aldonic acids
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Physical Education & Sports Medicine (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Animal Behavior & Ethology (AREA)
- Neurology (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161550610P | 2011-10-24 | 2011-10-24 | |
| PCT/US2012/061737 WO2013063149A1 (en) | 2011-10-24 | 2012-10-24 | Sialic acid analogs |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2807890T3 true ES2807890T3 (es) | 2021-02-24 |
Family
ID=48168447
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES12843460T Active ES2807890T3 (es) | 2011-10-24 | 2012-10-24 | Análogos de ácido siálico |
Country Status (13)
| Country | Link |
|---|---|
| US (5) | US8840926B2 (enExample) |
| EP (1) | EP2771348B1 (enExample) |
| JP (1) | JP6196224B2 (enExample) |
| KR (1) | KR102049214B1 (enExample) |
| CN (1) | CN103974965B (enExample) |
| AU (1) | AU2012328874B2 (enExample) |
| BR (1) | BR112014009760B1 (enExample) |
| CA (1) | CA2849114C (enExample) |
| ES (1) | ES2807890T3 (enExample) |
| HK (1) | HK1201067A1 (enExample) |
| IL (1) | IL231714B (enExample) |
| MX (1) | MX347541B (enExample) |
| WO (1) | WO2013063149A1 (enExample) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9241896B2 (en) | 2008-12-19 | 2016-01-26 | Ultragenyx Pharmaceutical Inc. | Methods and formulations for treating sialic acid deficiencies |
| CA2805222A1 (en) | 2010-07-13 | 2012-01-19 | Ultragenyx Pharmaceutical Inc. | Methods and formulations for treating sialic acid deficiencies |
| CN103974965B (zh) | 2011-10-24 | 2019-09-24 | 奥特吉尼克斯制药公司 | 唾液酸类似物 |
| BR112014017587A8 (pt) * | 2012-01-18 | 2017-07-04 | Ultragenyx Pharmaceutical Inc | métodos e formulações para o tratamento de deficiências de ácido siálico |
| US10385085B2 (en) | 2015-09-14 | 2019-08-20 | Ultragenyx Pharmaceutical Inc. | Crystal forms of sialic acid or salt or solvate thereof |
| WO2024173797A1 (en) * | 2023-02-17 | 2024-08-22 | Ultragenyx Pharmaceutical Inc. | Crystalline forms of sialic acid derivatives and methods for their use |
Family Cites Families (26)
| Publication number | Priority date | Publication date | Assignee | Title |
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| JPS6168418A (ja) | 1984-09-11 | 1986-04-08 | Kanto Ishi Pharma Co Ltd | 去痰薬 |
| JPS63139193A (ja) * | 1986-11-28 | 1988-06-10 | Mect Corp | シアル酸誘導体１，７−ラクトン |
| US6156544A (en) | 1993-06-09 | 2000-12-05 | Glaxo Group Limited | Process for the preparation of N-acetylneuraminic acid |
| CN1090022C (zh) | 1995-04-04 | 2002-09-04 | 俄克拉荷马创伤治疗所 | 通过光动力疗法与免疫佐剂联合应用治疗癌症 |
| US5624677A (en) | 1995-06-13 | 1997-04-29 | Pentech Pharmaceuticals, Inc. | Controlled release of drugs delivered by sublingual or buccal administration |
| DE69942721D1 (de) | 1998-04-10 | 2010-10-14 | Mitsubishi Chem Corp | Sialsäure-derivate enthaltende feste dispersion |
| KR20030006721A (ko) | 2001-07-14 | 2003-01-23 | 삼성전자 주식회사 | 리소그라피 시스템 및 이를 이용한 레티클 표면의 파티클제거방법 |
| BR0311978A (pt) | 2002-06-21 | 2005-03-22 | Novo Nordisk Healthcare Ag | Preparação, método para preparar a mesma, formulação farmacêutica, métodos para tratar de uma sìndrome responsiva ao fator vii, para prevenir hemorragias indesejáveis, para prevenir coagulação sanguìnea indesejável e para prevenir as reações mediadas pelo fator tecidual, e, uso de uma preparação |
| US7238677B2 (en) | 2003-03-28 | 2007-07-03 | Kimberly-Clark Worldwide, Inc. | Prevention of urogenital infections |
| CA2549195A1 (en) * | 2003-12-09 | 2005-06-23 | Spherics, Inc. | Bioadhesive polymers with catechol functionality |
| CA2599733C (en) | 2005-03-03 | 2013-05-28 | Mannatech, Inc. | Methods and compositons for modified release of nutritional supplements |
| EP2086515A2 (en) * | 2006-03-02 | 2009-08-12 | Vaunnex, Inc. | Rate-controlled bioadhesive oral dosage formulations |
| WO2008027557A2 (en) * | 2006-08-31 | 2008-03-06 | Spherics, Inc. | Topiramate compositions and methods of enhancing its bioavailability |
| US8410063B2 (en) | 2007-05-31 | 2013-04-02 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | N-acetyl mannosamine as a therapeutic agent |
| EP2192923A2 (en) | 2007-08-27 | 2010-06-09 | Massachusetts Institute of Technology | Bi-functional polymer-attached inhibitors of influenza virus |
| CN102316730A (zh) | 2008-05-09 | 2012-01-11 | 天雅瑞药业有限公司 | 用于减轻全身性炎症和/或血管炎症的n-乙酰半胱氨酸(nac)的控释 |
| KR101116864B1 (ko) | 2008-08-01 | 2012-02-29 | 주식회사 베네비오 | 고지혈증, 지방간 또는 비만의 예방 또는 치료용 조성물 |
| US9241896B2 (en) | 2008-12-19 | 2016-01-26 | Ultragenyx Pharmaceutical Inc. | Methods and formulations for treating sialic acid deficiencies |
| US20100160363A1 (en) | 2008-12-19 | 2010-06-24 | Aaipharma Services Corp. | Extended-release pharmaceutical formulations |
| US20100159001A1 (en) | 2008-12-19 | 2010-06-24 | Cardinal John R | Extended-Release Pharmaceutical Formulations |
| WO2010131712A1 (ja) * | 2009-05-15 | 2010-11-18 | 財団法人ヒューマンサイエンス振興財団 | Ｇｎｅタンパク質の機能低下に起因する疾患の治療用医薬剤、食品組成物、食品添加物 |
| CA2805222A1 (en) | 2010-07-13 | 2012-01-19 | Ultragenyx Pharmaceutical Inc. | Methods and formulations for treating sialic acid deficiencies |
| CN103974965B (zh) | 2011-10-24 | 2019-09-24 | 奥特吉尼克斯制药公司 | 唾液酸类似物 |
| BR112014017587A8 (pt) | 2012-01-18 | 2017-07-04 | Ultragenyx Pharmaceutical Inc | métodos e formulações para o tratamento de deficiências de ácido siálico |
| CN107207552B (zh) | 2015-01-28 | 2021-03-26 | 协和发酵生化株式会社 | N-乙酰神经氨酸铵盐无水物的晶体及其制造方法 |
| US10385085B2 (en) | 2015-09-14 | 2019-08-20 | Ultragenyx Pharmaceutical Inc. | Crystal forms of sialic acid or salt or solvate thereof |
-
2012
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2014
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- 2014-08-15 US US14/461,295 patent/US9221858B2/en active Active
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2015
- 2015-11-18 US US14/944,779 patent/US10065981B2/en active Active
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2018
- 2018-07-31 US US16/050,343 patent/US10457701B2/en active Active
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2019
- 2019-09-16 US US16/571,589 patent/US10889607B2/en active Active
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| US20190127409A1 (en) | 2019-05-02 |
| KR20140084277A (ko) | 2014-07-04 |
| US20160297846A1 (en) | 2016-10-13 |
| US10457701B2 (en) | 2019-10-29 |
| EP2771348B1 (en) | 2020-05-20 |
| BR112014009760A8 (pt) | 2018-01-16 |
| US20150038693A1 (en) | 2015-02-05 |
| CN103974965B (zh) | 2019-09-24 |
| CN103974965A (zh) | 2014-08-06 |
| KR102049214B1 (ko) | 2019-11-28 |
| CA2849114A1 (en) | 2013-05-02 |
| US9221858B2 (en) | 2015-12-29 |
| AU2012328874A1 (en) | 2014-04-10 |
| US10889607B2 (en) | 2021-01-12 |
| HK1201067A1 (en) | 2015-08-21 |
| MX2014004928A (es) | 2014-11-10 |
| BR112014009760A2 (pt) | 2017-04-18 |
| US8840926B2 (en) | 2014-09-23 |
| US10065981B2 (en) | 2018-09-04 |
| CA2849114C (en) | 2020-12-15 |
| IL231714B (en) | 2018-10-31 |
| WO2013063149A1 (en) | 2013-05-02 |
| US20130122094A1 (en) | 2013-05-16 |
| MX347541B (es) | 2017-04-28 |
| BR112014009760B1 (pt) | 2022-11-29 |
| EP2771348A1 (en) | 2014-09-03 |
| EP2771348A4 (en) | 2015-09-09 |
| JP2014530882A (ja) | 2014-11-20 |
| US20200131215A1 (en) | 2020-04-30 |
| IL231714A0 (en) | 2014-05-28 |
| AU2012328874B2 (en) | 2017-08-31 |
| JP6196224B2 (ja) | 2017-09-13 |
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