HK1178887A1 - 2,5-substituted oxazolopyrimidine derivatives as edg-1 agonists edg-1 25- - Google Patents
2,5-substituted oxazolopyrimidine derivatives as edg-1 agonists edg-1 25-Info
- Publication number
- HK1178887A1 HK1178887A1 HK13105593.5A HK13105593A HK1178887A1 HK 1178887 A1 HK1178887 A1 HK 1178887A1 HK 13105593 A HK13105593 A HK 13105593A HK 1178887 A1 HK1178887 A1 HK 1178887A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- edg
- agonists
- derivatives
- substituted oxazolopyrimidine
- substituted
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/22—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains four or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Endocrinology (AREA)
- Emergency Medicine (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Dermatology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP10305044 | 2010-01-14 | ||
| PCT/EP2011/050303 WO2011086081A1 (de) | 2010-01-14 | 2011-01-12 | 2,5-substituierte oxazolopyrimidinderivate |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HK1178887A1 true HK1178887A1 (en) | 2013-09-19 |
Family
ID=41800382
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HK13105593.5A HK1178887A1 (en) | 2010-01-14 | 2013-05-10 | 2,5-substituted oxazolopyrimidine derivatives as edg-1 agonists edg-1 25- |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US9040544B2 (ru) |
| EP (1) | EP2523963B1 (ru) |
| JP (1) | JP5841069B2 (ru) |
| KR (1) | KR101764607B1 (ru) |
| CN (1) | CN102834400B (ru) |
| AR (1) | AR079885A1 (ru) |
| AU (1) | AU2011206617B2 (ru) |
| BR (1) | BR112012017484A2 (ru) |
| CA (1) | CA2784565C (ru) |
| DK (1) | DK2523963T3 (ru) |
| ES (1) | ES2524712T3 (ru) |
| HK (1) | HK1178887A1 (ru) |
| IL (1) | IL220719A (ru) |
| MX (1) | MX2012007837A (ru) |
| MY (1) | MY159857A (ru) |
| PT (1) | PT2523963E (ru) |
| RU (1) | RU2554874C2 (ru) |
| SG (1) | SG182483A1 (ru) |
| TW (1) | TWI544926B (ru) |
| UY (1) | UY33181A (ru) |
| WO (1) | WO2011086081A1 (ru) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| UY33176A (es) | 2010-01-13 | 2011-08-31 | Sanofi Aventis | Derivados de oxazolopirimidina sustituida en 2, 5, 7. |
| TWI478929B (zh) | 2010-01-13 | 2015-04-01 | Sanofi Aventis | 含２，５，７－經取代唑并嘧啶環之羧酸衍生物 |
| MY156476A (en) * | 2010-01-14 | 2016-02-26 | Sanofi Sa | Heterocyclic carboxylic acid derivatives having a 2,5-substituted oxazolopyrimidine ring |
| PT2523962E (pt) * | 2010-01-14 | 2014-02-06 | Sanofi Sa | Derivados de ácidos carboxílicos com um anel oxazolopirimidina substituído em 2,5 |
| US9321787B2 (en) | 2011-07-07 | 2016-04-26 | Sanofi | Carboxylic acid derivatives having an oxazolo[5,4-d]pyrimidine ring |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3679682A (en) * | 1970-04-23 | 1972-07-25 | Fmc Corp | CERTAIN 5H-ISOXAZOLO{8 5,4-d{9 PYRIMIDIN-4-ONES |
| JP2006524672A (ja) * | 2003-04-25 | 2006-11-02 | ユニバーシティー・カッレッジ・カーディフ・コンサルタンツ・リミテッド | ウイルス感染の治療において使用するための複素環式化合物 |
| JP4638410B2 (ja) * | 2003-04-30 | 2011-02-23 | ノバルティス アーゲー | スフィンゴシン−１−ホスフェートレセプターモジュレーターとしての、アミノプロパノール誘導体 |
| PE20050158A1 (es) * | 2003-05-19 | 2005-05-12 | Irm Llc | Compuestos inmunosupresores y composiciones |
| ATE537825T1 (de) * | 2003-05-19 | 2012-01-15 | Irm Llc | Immunosuppressive verbindungen und zusammensetzungen |
| CN101291908A (zh) * | 2005-08-23 | 2008-10-22 | Irm责任有限公司 | 免疫抑制剂化合物和组合物 |
| AU2006317689B2 (en) | 2005-11-23 | 2013-07-25 | Epix Delaware, Inc. | S1P receptor modulating compounds and use thereof |
| US7919519B2 (en) * | 2005-11-23 | 2011-04-05 | Epix Pharmaceuticals Inc. | S1P receptor modulating compounds and use thereof |
| EP2364976B1 (en) * | 2007-03-21 | 2014-10-08 | EPIX Pharmaceuticals, Inc. | S1P receptor modulating compounds and use thereof |
| WO2009013545A2 (en) * | 2007-07-26 | 2009-01-29 | Astrazeneca Ab | Chemical compounds |
| US7863291B2 (en) * | 2008-04-23 | 2011-01-04 | Bristol-Myers Squibb Company | Quinuclidine compounds as alpha-7 nicotinic acetylcholine receptor ligands |
| TW201000099A (en) * | 2008-06-20 | 2010-01-01 | Amgen Inc | S1P1 receptor agonists and use thereof |
| CN102159582B (zh) * | 2008-07-15 | 2014-05-07 | 赛诺菲-安万特 | 作为Edg-1受体激动剂的噁唑并嘧啶 |
| TWI478929B (zh) | 2010-01-13 | 2015-04-01 | Sanofi Aventis | 含２，５，７－經取代唑并嘧啶環之羧酸衍生物 |
| UY33176A (es) | 2010-01-13 | 2011-08-31 | Sanofi Aventis | Derivados de oxazolopirimidina sustituida en 2, 5, 7. |
| UY33178A (es) * | 2010-01-13 | 2011-08-31 | Sanofi Aventis | Derivados de ácido carboxílico heteroxíclicos que comprenden un anillo de oxazolopirimidina 2, 5, 7-sustituido |
| MY156476A (en) | 2010-01-14 | 2016-02-26 | Sanofi Sa | Heterocyclic carboxylic acid derivatives having a 2,5-substituted oxazolopyrimidine ring |
| PT2523962E (pt) | 2010-01-14 | 2014-02-06 | Sanofi Sa | Derivados de ácidos carboxílicos com um anel oxazolopirimidina substituído em 2,5 |
-
2011
- 2011-01-12 KR KR1020127021237A patent/KR101764607B1/ko active IP Right Grant
- 2011-01-12 AU AU2011206617A patent/AU2011206617B2/en not_active Ceased
- 2011-01-12 EP EP11700529.8A patent/EP2523963B1/de active Active
- 2011-01-12 CN CN201180014162.5A patent/CN102834400B/zh active Active
- 2011-01-12 SG SG2012051397A patent/SG182483A1/en unknown
- 2011-01-12 CA CA2784565A patent/CA2784565C/en not_active Expired - Fee Related
- 2011-01-12 DK DK11700529.8T patent/DK2523963T3/en active
- 2011-01-12 JP JP2012548412A patent/JP5841069B2/ja active Active
- 2011-01-12 RU RU2012134636/04A patent/RU2554874C2/ru active
- 2011-01-12 TW TW100101051A patent/TWI544926B/zh not_active IP Right Cessation
- 2011-01-12 ES ES11700529.8T patent/ES2524712T3/es active Active
- 2011-01-12 MX MX2012007837A patent/MX2012007837A/es active IP Right Grant
- 2011-01-12 UY UY0001033181A patent/UY33181A/es not_active Application Discontinuation
- 2011-01-12 MY MYPI2012002622A patent/MY159857A/en unknown
- 2011-01-12 AR ARP110100094A patent/AR079885A1/es active IP Right Grant
- 2011-01-12 BR BR112012017484-3A patent/BR112012017484A2/pt active Search and Examination
- 2011-01-12 PT PT117005298T patent/PT2523963E/pt unknown
- 2011-01-12 WO PCT/EP2011/050303 patent/WO2011086081A1/de active Application Filing
- 2011-01-14 US US13/521,825 patent/US9040544B2/en active Active
-
2012
- 2012-07-02 IL IL220719A patent/IL220719A/en active IP Right Grant
-
2013
- 2013-05-10 HK HK13105593.5A patent/HK1178887A1/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| AR079885A1 (es) | 2012-02-29 |
| MX2012007837A (es) | 2012-07-30 |
| WO2011086081A1 (de) | 2011-07-21 |
| KR20120115403A (ko) | 2012-10-17 |
| PT2523963E (pt) | 2014-11-06 |
| JP5841069B2 (ja) | 2016-01-06 |
| TW201134473A (en) | 2011-10-16 |
| TWI544926B (zh) | 2016-08-11 |
| MY159857A (en) | 2017-02-15 |
| JP2013517243A (ja) | 2013-05-16 |
| ES2524712T3 (es) | 2014-12-11 |
| AU2011206617B2 (en) | 2015-07-16 |
| IL220719A (en) | 2015-03-31 |
| EP2523963A1 (de) | 2012-11-21 |
| US9040544B2 (en) | 2015-05-26 |
| SG182483A1 (en) | 2012-08-30 |
| BR112012017484A2 (pt) | 2020-08-25 |
| RU2554874C2 (ru) | 2015-06-27 |
| CA2784565A1 (en) | 2011-07-21 |
| US20130072501A1 (en) | 2013-03-21 |
| KR101764607B1 (ko) | 2017-08-03 |
| CN102834400B (zh) | 2015-06-10 |
| DK2523963T3 (en) | 2014-12-01 |
| RU2012134636A (ru) | 2014-02-20 |
| UY33181A (es) | 2011-08-31 |
| EP2523963B1 (de) | 2014-08-27 |
| AU2011206617A1 (en) | 2012-08-02 |
| CN102834400A (zh) | 2012-12-19 |
| CA2784565C (en) | 2018-03-13 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PC | Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee) |
Effective date: 20220108 |