HK1178887A1 - 作為 激動劑的 -取代的噁唑並嘧啶衍生物 - Google Patents
作為 激動劑的 -取代的噁唑並嘧啶衍生物Info
- Publication number
- HK1178887A1 HK1178887A1 HK13105593.5A HK13105593A HK1178887A1 HK 1178887 A1 HK1178887 A1 HK 1178887A1 HK 13105593 A HK13105593 A HK 13105593A HK 1178887 A1 HK1178887 A1 HK 1178887A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- edg
- agonists
- derivatives
- substituted oxazolopyrimidine
- substituted
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/22—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains four or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Obesity (AREA)
- Endocrinology (AREA)
- Hematology (AREA)
- Emergency Medicine (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Dermatology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP10305044 | 2010-01-14 | ||
| PCT/EP2011/050303 WO2011086081A1 (de) | 2010-01-14 | 2011-01-12 | 2,5-substituierte oxazolopyrimidinderivate |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HK1178887A1 true HK1178887A1 (zh) | 2013-09-19 |
Family
ID=41800382
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HK13105593.5A HK1178887A1 (zh) | 2010-01-14 | 2013-05-10 | 作為 激動劑的 -取代的噁唑並嘧啶衍生物 |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US9040544B2 (zh) |
| EP (1) | EP2523963B1 (zh) |
| JP (1) | JP5841069B2 (zh) |
| KR (1) | KR101764607B1 (zh) |
| CN (1) | CN102834400B (zh) |
| AR (1) | AR079885A1 (zh) |
| AU (1) | AU2011206617B2 (zh) |
| BR (1) | BR112012017484A2 (zh) |
| CA (1) | CA2784565C (zh) |
| DK (1) | DK2523963T3 (zh) |
| ES (1) | ES2524712T3 (zh) |
| HK (1) | HK1178887A1 (zh) |
| IL (1) | IL220719A (zh) |
| MX (1) | MX2012007837A (zh) |
| MY (1) | MY159857A (zh) |
| PT (1) | PT2523963E (zh) |
| RU (1) | RU2554874C2 (zh) |
| SG (1) | SG182483A1 (zh) |
| TW (1) | TWI544926B (zh) |
| UY (1) | UY33181A (zh) |
| WO (1) | WO2011086081A1 (zh) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| UY33177A (es) | 2010-01-13 | 2011-08-31 | Sanofi Aventis | Derivados de ácido carboxílico que comprenden un anillo de oxazolopirimidina 2, 5, 7-sustituido |
| TWI485153B (zh) | 2010-01-13 | 2015-05-21 | Sanofi Aventis | ２，５，７－經取代唑并嘧啶衍生物 |
| CN102791717B (zh) * | 2010-01-14 | 2016-03-30 | 赛诺菲 | 具有2,5-取代的噁唑并嘧啶环的羧酸衍生物 |
| PT2523960E (pt) * | 2010-01-14 | 2013-12-09 | Sanofi Sa | Derivados heterocíclicos de ácidos carboxílicos com um anel oxazolopirimidina substituído em 2,5 |
| US9321787B2 (en) | 2011-07-07 | 2016-04-26 | Sanofi | Carboxylic acid derivatives having an oxazolo[5,4-d]pyrimidine ring |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3679682A (en) * | 1970-04-23 | 1972-07-25 | Fmc Corp | CERTAIN 5H-ISOXAZOLO{8 5,4-d{9 PYRIMIDIN-4-ONES |
| WO2004096813A1 (en) * | 2003-04-25 | 2004-11-11 | University College Cardiff Consultants Limited | Heterocyclic compounds for use in the treatment of viral infections |
| EP1622866B1 (en) * | 2003-04-30 | 2012-07-25 | Novartis AG | Aminopropanol derivatives as sphingosine-1-phosphate receptor modulators |
| AR044402A1 (es) * | 2003-05-19 | 2005-09-14 | Irm Llc | Compuestos heterociclicos y su uso como inmunodepresores. composiciones farmaceuticas que los contienen. |
| BRPI0410454A (pt) * | 2003-05-19 | 2006-06-13 | Irm Llc | composições e compostos imunossupressores |
| CA2619101A1 (en) * | 2005-08-23 | 2007-03-01 | Irm Llc | Immunosuppressant compounds and compositions |
| WO2007061458A2 (en) | 2005-11-23 | 2007-05-31 | Epix Delaware, Inc. | S1p receptor modulating compounds and use thereof |
| US7919519B2 (en) * | 2005-11-23 | 2011-04-05 | Epix Pharmaceuticals Inc. | S1P receptor modulating compounds and use thereof |
| WO2007109334A2 (en) * | 2006-03-21 | 2007-09-27 | Epix Delaware, Inc. | Sip receptor modulating compounds and use thereof |
| WO2009013545A2 (en) * | 2007-07-26 | 2009-01-29 | Astrazeneca Ab | Chemical compounds |
| US7863291B2 (en) * | 2008-04-23 | 2011-01-04 | Bristol-Myers Squibb Company | Quinuclidine compounds as alpha-7 nicotinic acetylcholine receptor ligands |
| TW201000099A (en) * | 2008-06-20 | 2010-01-01 | Amgen Inc | S1P1 receptor agonists and use thereof |
| RU2503680C2 (ru) * | 2008-07-15 | 2014-01-10 | Санофи-Авентис | ОКСАЗОЛОПИРИМИДИНЫ КАК АГОНИСТЫ РЕЦЕПТОРА Edg-1 |
| TWI485153B (zh) * | 2010-01-13 | 2015-05-21 | Sanofi Aventis | ２，５，７－經取代唑并嘧啶衍生物 |
| UY33177A (es) * | 2010-01-13 | 2011-08-31 | Sanofi Aventis | Derivados de ácido carboxílico que comprenden un anillo de oxazolopirimidina 2, 5, 7-sustituido |
| AR079982A1 (es) | 2010-01-13 | 2012-03-07 | Sanofi Aventis | Derivados de acido carboxilico heterociclicos que comprenden un anillo de oxazolopirimidina 2,5,7- sustituido., composiciones farmaceuticas y procesos para prepararlos. |
| PT2523960E (pt) * | 2010-01-14 | 2013-12-09 | Sanofi Sa | Derivados heterocíclicos de ácidos carboxílicos com um anel oxazolopirimidina substituído em 2,5 |
| CN102791717B (zh) * | 2010-01-14 | 2016-03-30 | 赛诺菲 | 具有2,5-取代的噁唑并嘧啶环的羧酸衍生物 |
-
2011
- 2011-01-12 JP JP2012548412A patent/JP5841069B2/ja active Active
- 2011-01-12 ES ES11700529.8T patent/ES2524712T3/es active Active
- 2011-01-12 AU AU2011206617A patent/AU2011206617B2/en not_active Ceased
- 2011-01-12 DK DK11700529.8T patent/DK2523963T3/en active
- 2011-01-12 MY MYPI2012002622A patent/MY159857A/en unknown
- 2011-01-12 SG SG2012051397A patent/SG182483A1/en unknown
- 2011-01-12 WO PCT/EP2011/050303 patent/WO2011086081A1/de active Application Filing
- 2011-01-12 CA CA2784565A patent/CA2784565C/en not_active Expired - Fee Related
- 2011-01-12 BR BR112012017484-3A patent/BR112012017484A2/pt active Search and Examination
- 2011-01-12 AR ARP110100094A patent/AR079885A1/es active IP Right Grant
- 2011-01-12 PT PT117005298T patent/PT2523963E/pt unknown
- 2011-01-12 CN CN201180014162.5A patent/CN102834400B/zh active Active
- 2011-01-12 RU RU2012134636/04A patent/RU2554874C2/ru active
- 2011-01-12 TW TW100101051A patent/TWI544926B/zh not_active IP Right Cessation
- 2011-01-12 UY UY0001033181A patent/UY33181A/es not_active Application Discontinuation
- 2011-01-12 KR KR1020127021237A patent/KR101764607B1/ko active IP Right Grant
- 2011-01-12 MX MX2012007837A patent/MX2012007837A/es active IP Right Grant
- 2011-01-12 EP EP11700529.8A patent/EP2523963B1/de active Active
- 2011-01-14 US US13/521,825 patent/US9040544B2/en active Active
-
2012
- 2012-07-02 IL IL220719A patent/IL220719A/en active IP Right Grant
-
2013
- 2013-05-10 HK HK13105593.5A patent/HK1178887A1/zh not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| EP2523963A1 (de) | 2012-11-21 |
| EP2523963B1 (de) | 2014-08-27 |
| WO2011086081A1 (de) | 2011-07-21 |
| CA2784565C (en) | 2018-03-13 |
| MY159857A (en) | 2017-02-15 |
| ES2524712T3 (es) | 2014-12-11 |
| PT2523963E (pt) | 2014-11-06 |
| MX2012007837A (es) | 2012-07-30 |
| US9040544B2 (en) | 2015-05-26 |
| TW201134473A (en) | 2011-10-16 |
| RU2554874C2 (ru) | 2015-06-27 |
| AR079885A1 (es) | 2012-02-29 |
| AU2011206617B2 (en) | 2015-07-16 |
| SG182483A1 (en) | 2012-08-30 |
| KR101764607B1 (ko) | 2017-08-03 |
| US20130072501A1 (en) | 2013-03-21 |
| IL220719A (en) | 2015-03-31 |
| JP2013517243A (ja) | 2013-05-16 |
| JP5841069B2 (ja) | 2016-01-06 |
| UY33181A (es) | 2011-08-31 |
| RU2012134636A (ru) | 2014-02-20 |
| BR112012017484A2 (pt) | 2020-08-25 |
| CN102834400A (zh) | 2012-12-19 |
| CN102834400B (zh) | 2015-06-10 |
| CA2784565A1 (en) | 2011-07-21 |
| AU2011206617A1 (en) | 2012-08-02 |
| KR20120115403A (ko) | 2012-10-17 |
| DK2523963T3 (en) | 2014-12-01 |
| TWI544926B (zh) | 2016-08-11 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PC | Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee) |
Effective date: 20220108 |