HK1175242A1 - Methods and reagents for improved detection of amyloid beta peptides - Google Patents
Methods and reagents for improved detection of amyloid beta peptidesInfo
- Publication number
- HK1175242A1 HK1175242A1 HK13102393.4A HK13102393A HK1175242A1 HK 1175242 A1 HK1175242 A1 HK 1175242A1 HK 13102393 A HK13102393 A HK 13102393A HK 1175242 A1 HK1175242 A1 HK 1175242A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- reagents
- methods
- amyloid beta
- improved detection
- beta peptides
- Prior art date
Links
- 102000013455 Amyloid beta-Peptides Human genes 0.000 title 1
- 108010090849 Amyloid beta-Peptides Proteins 0.000 title 1
- 239000003153 chemical reaction reagent Substances 0.000 title 1
- 238000001514 detection method Methods 0.000 title 1
- 238000000034 method Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
- G01N33/6896—Neurological disorders, e.g. Alzheimer's disease
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/46—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
- G01N2333/47—Assays involving proteins of known structure or function as defined in the subgroups
- G01N2333/4701—Details
- G01N2333/4709—Amyloid plaque core protein
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Organic Chemistry (AREA)
- Analytical Chemistry (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Pathology (AREA)
- Physics & Mathematics (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Cell Biology (AREA)
- Medicinal Chemistry (AREA)
- Neurology (AREA)
- General Physics & Mathematics (AREA)
- Neurosurgery (AREA)
- Food Science & Technology (AREA)
- Biophysics (AREA)
- General Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Hospice & Palliative Care (AREA)
- Oncology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP09382279 | 2009-12-11 | ||
| PCT/EP2010/069474 WO2011070174A1 (en) | 2009-12-11 | 2010-12-13 | Methods and reagents for improved detection of amyloid beta peptides |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HK1175242A1 true HK1175242A1 (en) | 2013-06-28 |
Family
ID=41818879
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HK13102393.4A HK1175242A1 (en) | 2009-12-11 | 2013-02-26 | Methods and reagents for improved detection of amyloid beta peptides |
Country Status (21)
| Country | Link |
|---|---|
| US (2) | US20120264642A1 (ru) |
| EP (1) | EP2510359B1 (ru) |
| JP (1) | JP5745531B2 (ru) |
| KR (1) | KR101531949B1 (ru) |
| CN (1) | CN102713633B (ru) |
| AR (1) | AR079443A1 (ru) |
| AU (1) | AU2010329844B2 (ru) |
| BR (1) | BR112012014060B8 (ru) |
| CA (1) | CA2782250C (ru) |
| DK (1) | DK2510359T3 (ru) |
| ES (1) | ES2552627T3 (ru) |
| HK (1) | HK1175242A1 (ru) |
| HU (1) | HUE028105T2 (ru) |
| IL (1) | IL220276A (ru) |
| IN (1) | IN2012DN05056A (ru) |
| MX (1) | MX2012006512A (ru) |
| PL (1) | PL2510359T3 (ru) |
| PT (1) | PT2510359E (ru) |
| RU (1) | RU2554774C2 (ru) |
| TW (1) | TWI509246B (ru) |
| WO (1) | WO2011070174A1 (ru) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20140128229A (ko) * | 2013-04-26 | 2014-11-05 | 한국과학기술연구원 | 체내 단백질 응집체의 용해를 이용한 단백질의 비정상적인 응집 또는 미스폴딩과 관련된 질환 또는 질병을 진단하는 혈액진단키트 |
| CN106574930B (zh) * | 2014-05-22 | 2019-09-03 | 株式会社岛津制作所 | 评价脑内的淀粉样蛋白β肽蓄积状态的替代性生物标记物和其分析方法 |
| US10139419B2 (en) * | 2014-09-05 | 2018-11-27 | System Of Systems Analytics, Inc. | Methods for detecting Aβ oligomers |
| KR101786859B1 (ko) * | 2015-04-30 | 2017-10-17 | 서울대학교산학협력단 | 혈장 내 아밀로이드베타의 농도를 통해 알츠하이머병을 임상학적 및 병리학적으로 모니터링하는 방법 |
| RU2611408C1 (ru) * | 2015-09-23 | 2017-02-21 | Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования "Чувашский государственный университет имени И.Н. Ульянова" | Способ флуоресцентного гистологического выявления амилоида |
| GB201518675D0 (en) * | 2015-10-21 | 2015-12-02 | Cellcap Technologies Ltd | Detection of structural forms of proteins |
| EP3760640A4 (en) * | 2018-02-27 | 2021-11-17 | Shimadzu Corporation | ANTIBODIES SPECIFICALLY RECOGNIZING THE N-TERMINAL END OF APP669-X, AND METHOD OF IMMUNOLOGICAL ASSAY |
| WO2019167128A1 (ja) * | 2018-02-27 | 2019-09-06 | 株式会社 島津製作所 | サンドイッチ型免疫測定法 |
| RU2708465C1 (ru) * | 2019-02-18 | 2019-12-09 | Федеральное Государственное Бюджетное Учреждение Науки Институт Молекулярной Биологии Им. В.А. Энгельгардта Российской Академии Наук (Имб Ран) | Способ детекции модификаций амилоидного пептида с помощью высокоспецифичных антител |
| CN113597429A (zh) * | 2019-03-01 | 2021-11-02 | 株式会社岛津制作所 | App669-711测定方法及测定用试剂盒 |
| GB201904810D0 (en) | 2019-04-05 | 2019-05-22 | Cynapsedx Ltd | The treatment of protein aggregation diseases |
| CN114072678A (zh) * | 2019-05-10 | 2022-02-18 | 奎斯特诊断投资有限责任公司 | 用于确定人血浆样本中的β-淀粉样蛋白42/40比率的多重测定 |
| WO2021009074A1 (en) | 2019-07-12 | 2021-01-21 | Adx Neurosciences Nv | Novel markers as early predictors of alzheimer's pathology |
| CN116574271B (zh) * | 2023-06-06 | 2023-12-19 | 苏州谱迪生物科技有限公司 | 一种用于免疫检测低丰度生物标志物信号级联放大的荧光树状大分子的制备方法及其应用 |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5976817A (en) * | 1996-10-31 | 1999-11-02 | Trustees Of Boston University | Diagnostic method for detecting Alzheimer's disease in living patients |
| US8173127B2 (en) * | 1997-04-09 | 2012-05-08 | Intellect Neurosciences, Inc. | Specific antibodies to amyloid beta peptide, pharmaceutical compositions and methods of use thereof |
| CZ2008595A3 (cs) | 2000-02-24 | 2017-05-03 | Washington University | Léčivo pro prevenci nebo léčení preklinické nebo klinické Alzheimerovy nemoci |
| TWI255272B (en) | 2000-12-06 | 2006-05-21 | Guriq Basi | Humanized antibodies that recognize beta amyloid peptide |
| CA2457145C (en) | 2001-08-17 | 2010-12-21 | Washington University | Assay method for alzheimer's disease |
| WO2004013172A2 (en) | 2002-07-24 | 2004-02-12 | Innogenetics N.V. | Fragments of beta-amyloid as targets for vaccination against alzheimer disease |
| ES2201929B1 (es) | 2002-09-12 | 2005-05-16 | Araclon Biotech, S.L. | Anticuerpos policlonales, metodo de preparacion y uso de los mismos. |
| US20040096907A1 (en) * | 2002-11-06 | 2004-05-20 | Bernd Bohrmann | Quantification of beta amyloid |
| ES2246178B1 (es) | 2003-05-08 | 2007-03-01 | Universidad De Zaragoza. | Uso de anticuerpos para el tratamiento de enfermedades amiloideas. |
| EP1480041A1 (en) * | 2003-05-22 | 2004-11-24 | Innogenetics N.V. | Method for the prediction, diagnosis and differential diagnosis of Alzheimer's disease |
| WO2005019828A1 (en) * | 2003-08-20 | 2005-03-03 | Amorfix Life Sciences Ltd. | Epitope protection assay and method for detecting protein conformations |
| CN101048662A (zh) | 2004-10-28 | 2007-10-03 | 三光纯药株式会社 | 阿尔茨海默氏病的检验方法及诊断试剂 |
| JP2008519988A (ja) | 2004-11-12 | 2008-06-12 | ファイザー・インク | アミロイド−ベータペプチドを測定する方法 |
| WO2007022015A1 (en) | 2005-08-12 | 2007-02-22 | Georgetown University | Methods to evaluate amyloid beta-lowering agents using wild-type mice |
| CA2626783A1 (en) | 2005-10-21 | 2007-05-03 | Merck & Co., Inc. | Anti-addl monoclonal antibody and use thereof |
| EP2020602A1 (en) * | 2007-08-02 | 2009-02-04 | Araclon Biotech | High sensitivty immunoassays and kits for the determination of peptides and proteins of biological interest |
| US20090246191A1 (en) * | 2007-10-11 | 2009-10-01 | University Of Tennessee Research Foundation | Preparation of Purified Covalently Cross-linked Abeta Oligomers and Uses Thereof |
| JP2013511734A (ja) * | 2009-11-24 | 2013-04-04 | プロビオドルグ エージー | アルツハイマー病又は軽度認知障害の診断のための新規診断方法 |
-
2010
- 2010-12-13 KR KR1020127018082A patent/KR101531949B1/ko active IP Right Grant
- 2010-12-13 MX MX2012006512A patent/MX2012006512A/es active IP Right Grant
- 2010-12-13 EP EP10787797.9A patent/EP2510359B1/en active Active
- 2010-12-13 AR ARP100104604A patent/AR079443A1/es active IP Right Grant
- 2010-12-13 TW TW099143622A patent/TWI509246B/zh not_active IP Right Cessation
- 2010-12-13 HU HUE10787797A patent/HUE028105T2/en unknown
- 2010-12-13 PT PT107877979T patent/PT2510359E/pt unknown
- 2010-12-13 JP JP2012542576A patent/JP5745531B2/ja active Active
- 2010-12-13 CN CN201080062241.9A patent/CN102713633B/zh active Active
- 2010-12-13 US US13/514,825 patent/US20120264642A1/en not_active Abandoned
- 2010-12-13 AU AU2010329844A patent/AU2010329844B2/en active Active
- 2010-12-13 DK DK10787797.9T patent/DK2510359T3/en active
- 2010-12-13 ES ES10787797.9T patent/ES2552627T3/es active Active
- 2010-12-13 CA CA2782250A patent/CA2782250C/en active Active
- 2010-12-13 WO PCT/EP2010/069474 patent/WO2011070174A1/en active Application Filing
- 2010-12-13 BR BR112012014060A patent/BR112012014060B8/pt active IP Right Grant
- 2010-12-13 PL PL10787797T patent/PL2510359T3/pl unknown
- 2010-12-13 RU RU2012129184/15A patent/RU2554774C2/ru active
-
2012
- 2012-06-07 IN IN5056DEN2012 patent/IN2012DN05056A/en unknown
- 2012-06-10 IL IL220276A patent/IL220276A/en active IP Right Grant
-
2013
- 2013-02-26 HK HK13102393.4A patent/HK1175242A1/xx not_active IP Right Cessation
-
2020
- 2020-08-05 US US16/985,387 patent/US20210011032A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| CA2782250A1 (en) | 2011-06-16 |
| DK2510359T3 (en) | 2015-12-07 |
| IN2012DN05056A (ru) | 2015-10-09 |
| RU2012129184A (ru) | 2014-01-20 |
| MX2012006512A (es) | 2012-08-17 |
| PT2510359E (pt) | 2015-12-02 |
| CN102713633B (zh) | 2015-03-11 |
| RU2554774C2 (ru) | 2015-06-27 |
| AR079443A1 (es) | 2012-01-25 |
| EP2510359B1 (en) | 2015-09-02 |
| BR112012014060B8 (pt) | 2021-07-27 |
| US20210011032A1 (en) | 2021-01-14 |
| IL220276A0 (en) | 2012-07-31 |
| BR112012014060A2 (pt) | 2016-12-13 |
| WO2011070174A1 (en) | 2011-06-16 |
| PL2510359T3 (pl) | 2016-02-29 |
| AU2010329844B2 (en) | 2015-07-16 |
| IL220276A (en) | 2016-02-29 |
| KR20120115306A (ko) | 2012-10-17 |
| CA2782250C (en) | 2016-08-30 |
| JP2013513791A (ja) | 2013-04-22 |
| KR101531949B1 (ko) | 2015-06-26 |
| EP2510359A1 (en) | 2012-10-17 |
| ES2552627T3 (es) | 2015-12-01 |
| US20120264642A1 (en) | 2012-10-18 |
| TWI509246B (zh) | 2015-11-21 |
| CN102713633A (zh) | 2012-10-03 |
| TW201131167A (en) | 2011-09-16 |
| AU2010329844A1 (en) | 2012-06-14 |
| BR112012014060B1 (pt) | 2021-01-19 |
| HUE028105T2 (en) | 2016-11-28 |
| JP5745531B2 (ja) | 2015-07-08 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PC | Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee) |
Effective date: 20231215 |