HK1174035A1 - Bromo-phenyl substituted thiazolyl dihydropyrimidines - Google Patents

Bromo-phenyl substituted thiazolyl dihydropyrimidines

Info

Publication number
HK1174035A1
HK1174035A1 HK13101360.5A HK13101360A HK1174035A1 HK 1174035 A1 HK1174035 A1 HK 1174035A1 HK 13101360 A HK13101360 A HK 13101360A HK 1174035 A1 HK1174035 A1 HK 1174035A1
Authority
HK
Hong Kong
Prior art keywords
bromo
phenyl substituted
substituted thiazolyl
dihydropyrimidines
thiazolyl dihydropyrimidines
Prior art date
Application number
HK13101360.5A
Other languages
English (en)
Inventor
Siegfried Goldmann
Jing Li
Yisong Liu
Original Assignee
Sunshine Lake Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=40155886&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HK1174035(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Sunshine Lake Pharma Co Ltd filed Critical Sunshine Lake Pharma Co Ltd
Publication of HK1174035A1 publication Critical patent/HK1174035A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Virology (AREA)
  • Engineering & Computer Science (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Plural Heterocyclic Compounds (AREA)
HK13101360.5A 2007-06-18 2013-01-31 Bromo-phenyl substituted thiazolyl dihydropyrimidines HK1174035A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN200710119019 2007-06-18

Publications (1)

Publication Number Publication Date
HK1174035A1 true HK1174035A1 (en) 2013-05-31

Family

ID=40155886

Family Applications (1)

Application Number Title Priority Date Filing Date
HK13101360.5A HK1174035A1 (en) 2007-06-18 2013-01-31 Bromo-phenyl substituted thiazolyl dihydropyrimidines

Country Status (15)

Country Link
US (4) USRE45004E1 (zh)
EP (2) EP2159224B1 (zh)
JP (2) JP5361879B2 (zh)
KR (1) KR101173892B1 (zh)
CN (2) CN101328171A (zh)
AU (1) AU2008265397C1 (zh)
BR (1) BRPI0813237B8 (zh)
CA (1) CA2691056C (zh)
DK (2) DK2514750T5 (zh)
ES (2) ES2442907T3 (zh)
HK (1) HK1174035A1 (zh)
PL (2) PL2514750T3 (zh)
PT (2) PT2159224E (zh)
RU (1) RU2443703C2 (zh)
WO (1) WO2008154817A1 (zh)

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CN101575318B (zh) * 2009-06-25 2012-02-08 中国人民解放军军事医学科学院毒物药物研究所 二氢嘧啶类化合物及其用于制备治疗和/或预防病毒性疾病的药物的用途
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CN103664925B (zh) * 2012-09-07 2018-01-23 广东东阳光药业有限公司 杂芳基取代的二氢嘧啶类化合物及其在药物中的应用
MA37942B1 (fr) 2012-09-10 2020-01-31 Hoffmann La Roche Hétéroaryldihydropyrimidines d'acide 6-aminé pour le traitement et la prophylaxie d'une infection par le virus de l'hépatite b
CN103664899B (zh) * 2012-09-11 2017-06-16 广东东阳光药业有限公司 杂芳基取代的二氢嘧啶类化合物及其在药物中的应用
CN104945394B (zh) 2012-09-27 2017-12-05 广东东阳光药业有限公司 二氢嘧啶衍生物的晶型
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US11639350B2 (en) 2017-06-27 2023-05-02 Janssen Pharmaceutica Nv Heteroaryldihydropyrimidine derivatives and methods of treating hepatitis B infections
CN107501257B (zh) * 2017-08-17 2020-05-29 山东大学 二氢嘧啶-三氮唑类衍生物及其制备方法与应用
CA3101373A1 (en) 2018-05-25 2019-11-28 Chia Tai Tianqing Pharmaceutical Group Co., Ltd. 2,3-dihydro-1h-pyrrolizine-7-formamide derivative and application thereof
US11053235B2 (en) 2018-08-09 2021-07-06 Janssen Sciences Ireland Unlimited Company Substituted 1,4-dihydropyrimidines for the treatment of HBV infection or HBV-induced diseases
JP7118354B2 (ja) 2018-08-23 2022-08-16 福建▲広▼生中霖生物科技有限公司 三環式化合物の結晶形及びその使用
WO2020255016A1 (en) 2019-06-18 2020-12-24 Janssen Sciences Ireland Unlimited Company Combination of hepatitis b virus (hbv) vaccines and dihydropyrimidine derivatives as capsid assembly modulators
CA3159096A1 (en) 2019-11-22 2021-05-27 Chia Tai Tianqing Pharmaceutical Group Co., Ltd Crystal form of nucleoprotein inhibitor and use thereof
EP4289842A1 (en) 2021-02-05 2023-12-13 Hepagene Therapeutics (HK) Limited Phenyldihydropyrimidine compound and use thereof
CN117136187A (zh) * 2021-06-24 2023-11-28 上海齐鲁制药研究中心有限公司 新型抗乙肝化合物

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Also Published As

Publication number Publication date
USRE45004E1 (en) 2014-07-08
PL2514750T3 (pl) 2014-05-30
USRE44987E1 (en) 2014-07-01
CN102066369A (zh) 2011-05-18
EP2514750B1 (en) 2013-11-20
DK2159224T3 (da) 2012-08-20
AU2008265397C1 (en) 2013-08-29
DK2514750T5 (en) 2014-02-17
US20120282221A1 (en) 2012-11-08
ES2391597T3 (es) 2012-11-28
PL2159224T3 (pl) 2012-12-31
US20100240655A1 (en) 2010-09-23
EP2159224A4 (en) 2011-08-03
JP5361879B2 (ja) 2013-12-04
BRPI0813237B1 (pt) 2020-01-07
JP2010530374A (ja) 2010-09-09
BRPI0813237A2 (pt) 2014-12-23
PT2514750E (pt) 2014-01-23
CN101328171A (zh) 2008-12-24
RU2443703C2 (ru) 2012-02-27
CA2691056C (en) 2014-03-11
RU2010101212A (ru) 2011-07-27
KR20100038104A (ko) 2010-04-12
KR101173892B1 (ko) 2012-08-16
WO2008154817A1 (fr) 2008-12-24
US8236797B2 (en) 2012-08-07
JP2013231036A (ja) 2013-11-14
AU2008265397B9 (en) 2011-08-04
AU2008265397B2 (en) 2011-07-21
EP2159224A1 (en) 2010-03-03
US8343969B2 (en) 2013-01-01
ES2442907T3 (es) 2014-02-14
AU2008265397A1 (en) 2008-12-24
JP5970421B2 (ja) 2016-08-17
DK2514750T3 (da) 2013-12-02
BRPI0813237B8 (pt) 2021-05-25
EP2514750A1 (en) 2012-10-24
CN102066369B (zh) 2013-05-29
PT2159224E (pt) 2012-10-24
CA2691056A1 (en) 2008-12-24
EP2159224B1 (en) 2012-08-01

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