HK1171755A1 - 螺環酰胺衍生物 - Google Patents

螺環酰胺衍生物

Info

Publication number
HK1171755A1
HK1171755A1 HK12112653.9A HK12112653A HK1171755A1 HK 1171755 A1 HK1171755 A1 HK 1171755A1 HK 12112653 A HK12112653 A HK 12112653A HK 1171755 A1 HK1171755 A1 HK 1171755A1
Authority
HK
Hong Kong
Prior art keywords
amide derivatives
spirocyclic amide
spirocyclic
derivatives
amide
Prior art date
Application number
HK12112653.9A
Other languages
English (en)
Inventor
Lilian Alcaraz
Andrew Bailey
Nicholas Kindon
Original Assignee
阿斯利康 瑞典 有限公司 帕爾梅根治療 協同 有限公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=41129405&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HK1171755(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by 阿斯利康 瑞典 有限公司 帕爾梅根治療 協同 有限公司 filed Critical 阿斯利康 瑞典 有限公司 帕爾梅根治療 協同 有限公司
Publication of HK1171755A1 publication Critical patent/HK1171755A1/zh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/10—Spiro-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/5386—1,4-Oxazines, e.g. morpholine spiro-condensed or forming part of bridged ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
    • C07D519/04—Dimeric indole alkaloids, e.g. vincaleucoblastine
HK12112653.9A 2009-07-31 2012-12-07 螺環酰胺衍生物 HK1171755A1 (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0913342.2A GB0913342D0 (en) 2009-07-31 2009-07-31 Compounds - 801
PCT/GB2010/051242 WO2011012896A2 (en) 2009-07-31 2010-07-29 Compounds - 801

Publications (1)

Publication Number Publication Date
HK1171755A1 true HK1171755A1 (zh) 2013-04-05

Family

ID=41129405

Family Applications (1)

Application Number Title Priority Date Filing Date
HK12112653.9A HK1171755A1 (zh) 2009-07-31 2012-12-07 螺環酰胺衍生物

Country Status (34)

Country Link
US (2) US8455483B2 (zh)
EP (1) EP2459572B1 (zh)
JP (1) JP5612092B2 (zh)
KR (1) KR101664525B1 (zh)
CN (1) CN102625808B (zh)
AR (1) AR080601A1 (zh)
AU (1) AU2010277384B2 (zh)
BR (1) BR112012008043A2 (zh)
CA (1) CA2768527C (zh)
CL (1) CL2012000263A1 (zh)
CO (1) CO6491034A2 (zh)
CR (1) CR20120054A (zh)
CU (1) CU24103B1 (zh)
DO (1) DOP2012000032A (zh)
EA (1) EA020566B1 (zh)
ES (1) ES2702467T3 (zh)
GB (1) GB0913342D0 (zh)
GT (1) GT201200028A (zh)
HK (1) HK1171755A1 (zh)
HN (1) HN2012000217A (zh)
IL (1) IL217557A (zh)
MX (1) MX2012001232A (zh)
MY (1) MY163117A (zh)
NI (1) NI201200018A (zh)
NZ (1) NZ597589A (zh)
PE (1) PE20121441A1 (zh)
SA (1) SA110310628B1 (zh)
SG (1) SG177634A1 (zh)
TR (1) TR201819140T4 (zh)
TW (1) TWI443103B (zh)
UA (1) UA106887C2 (zh)
UY (1) UY32814A (zh)
WO (1) WO2011012896A2 (zh)
ZA (1) ZA201201473B (zh)

Families Citing this family (10)

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MY149731A (en) 2008-02-06 2013-10-14 Astrazeneca Ab Compounds
GB0913342D0 (en) 2009-07-31 2009-09-16 Astrazeneca Ab Compounds - 801
TWI466885B (zh) 2009-07-31 2015-01-01 Japan Tobacco Inc 含氮螺環化合物及其醫藥用途
GB201021979D0 (en) * 2010-12-23 2011-02-02 Astrazeneca Ab New compound
GB201021992D0 (en) * 2010-12-23 2011-02-02 Astrazeneca Ab Compound
US10435375B2 (en) 2015-05-05 2019-10-08 Northwestern University CXCR4 chemokine receptor modulators
WO2018059537A1 (zh) * 2016-09-30 2018-04-05 四川海思科制药有限公司 一种二氮杂螺[5.5]十一碳烷衍生物及其用途
JP6963616B2 (ja) 2016-12-14 2021-11-10 ベイジン ショウバイ ファーマシューティカル カンパニー，リミティッド ４級アンモニウム塩構造を有する二官能性化合物
AU2018275552B2 (en) 2017-06-01 2022-01-20 Bristol-Myers Squibb Company Substituted nitrogen containing compounds
EP3682906A1 (en) * 2019-01-17 2020-07-22 Julius-Maximilians-Universität Würzburg Compound targeting norepinephrine transporter

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DE102004024453A1 (de) * 2004-05-14 2006-01-05 Boehringer Ingelheim Pharma Gmbh & Co. Kg Neue langwirksame Bronchodilatoren zur Behandlung von Atemwegserkrankungen
JP2008510015A (ja) 2004-08-16 2008-04-03 セラヴァンス， インコーポレーテッド β２アドレナリン作用性レセプターアゴニスト活性およびムスカリン性レセプターアンタゴニスト活性を有する化合物
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Also Published As

Publication number Publication date
UY32814A (es) 2011-02-28
BR112012008043A2 (pt) 2020-08-25
AU2010277384A1 (en) 2012-03-22
GB0913342D0 (en) 2009-09-16
US20130018037A1 (en) 2013-01-17
UA106887C2 (uk) 2014-10-27
AR080601A1 (es) 2012-04-25
CR20120054A (es) 2012-03-26
US8476265B2 (en) 2013-07-02
SA110310628B1 (ar) 2014-02-27
CN102625808A (zh) 2012-08-01
EP2459572B1 (en) 2018-09-12
EA020566B1 (ru) 2014-12-30
JP5612092B2 (ja) 2014-10-22
CU24103B1 (es) 2015-07-30
WO2011012896A2 (en) 2011-02-03
WO2011012896A3 (en) 2011-04-21
CO6491034A2 (es) 2012-07-31
SG177634A1 (en) 2012-02-28
US20110053909A1 (en) 2011-03-03
JP2013500958A (ja) 2013-01-10
TW201107335A (en) 2011-03-01
MY163117A (en) 2017-08-15
GT201200028A (es) 2013-09-26
MX2012001232A (es) 2012-03-26
EP2459572A2 (en) 2012-06-06
TWI443103B (zh) 2014-07-01
EA201290077A1 (ru) 2012-08-30
NZ597589A (en) 2013-12-20
CA2768527C (en) 2017-07-11
CN102625808B (zh) 2014-08-27
HN2012000217A (es) 2015-03-09
DOP2012000032A (es) 2017-08-15
ZA201201473B (en) 2012-11-28
IL217557A (en) 2015-01-29
IL217557A0 (en) 2012-02-29
TR201819140T4 (tr) 2019-01-21
ES2702467T3 (es) 2019-03-01
CL2012000263A1 (es) 2012-08-31
KR101664525B1 (ko) 2016-10-11
CU20120021A7 (es) 2012-06-21
AU2010277384B2 (en) 2014-01-30
CA2768527A1 (en) 2011-02-03
NI201200018A (es) 2012-09-10
PE20121441A1 (es) 2012-11-16
US8455483B2 (en) 2013-06-04
KR20120056838A (ko) 2012-06-04

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Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20210731