HK1161583A1 - Deacetylase inhibitors and uses thereof - Google Patents

Deacetylase inhibitors and uses thereof

Info

Publication number
HK1161583A1
HK1161583A1 HK12101694.3A HK12101694A HK1161583A1 HK 1161583 A1 HK1161583 A1 HK 1161583A1 HK 12101694 A HK12101694 A HK 12101694A HK 1161583 A1 HK1161583 A1 HK 1161583A1
Authority
HK
Hong Kong
Prior art keywords
deacetylase inhibitors
deacetylase
inhibitors
Prior art date
Application number
HK12101694.3A
Other languages
English (en)
Chinese (zh)
Inventor
湯偉平
詹姆斯‧埃利奧特‧布拉德納
斯圖爾特‧
‧施賴伯
Original Assignee
哈佛大學校長及研究員協會
達納-法伯癌症研究所有限公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 哈佛大學校長及研究員協會, 達納-法伯癌症研究所有限公司 filed Critical 哈佛大學校長及研究員協會
Publication of HK1161583A1 publication Critical patent/HK1161583A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C259/00—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups
    • C07C259/04—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids
    • C07C259/06—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids having carbon atoms of hydroxamic groups bound to hydrogen atoms or to acyclic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C251/00—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton
    • C07C251/72—Hydrazones
    • C07C251/86—Hydrazones having doubly-bound carbon atoms of hydrazone groups bound to carbon atoms of six-membered aromatic rings

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
HK12101694.3A 2008-07-23 2012-02-21 Deacetylase inhibitors and uses thereof HK1161583A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US8289908P 2008-07-23 2008-07-23
PCT/US2009/004235 WO2010011296A2 (fr) 2008-07-23 2009-07-22 Inhibiteurs de désacétylase et leurs utilisations

Publications (1)

Publication Number Publication Date
HK1161583A1 true HK1161583A1 (en) 2012-07-27

Family

ID=41570773

Family Applications (1)

Application Number Title Priority Date Filing Date
HK12101694.3A HK1161583A1 (en) 2008-07-23 2012-02-21 Deacetylase inhibitors and uses thereof

Country Status (11)

Country Link
US (2) US8440716B2 (fr)
EP (1) EP2321264B1 (fr)
JP (2) JP5665740B2 (fr)
KR (1) KR101708946B1 (fr)
CN (1) CN102164888B (fr)
AU (1) AU2009274549B2 (fr)
CA (1) CA2731730C (fr)
HK (1) HK1161583A1 (fr)
IL (1) IL210804A (fr)
RU (1) RU2515611C2 (fr)
WO (1) WO2010011296A2 (fr)

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WO2010011296A2 (fr) 2008-07-23 2010-01-28 President And Fellows Of Harvard College Inhibiteurs de désacétylase et leurs utilisations
WO2011019393A2 (fr) 2009-08-11 2011-02-17 President And Fellows Of Harvard College Inhibiteurs de hdac classe- et isoforme-spécifiques et utilisations de ceux-ci
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US10206925B2 (en) * 2016-06-07 2019-02-19 Eisai R&D Management Co, Ltd. Topical formulations of PDE-4 inhibitors and their methods of use
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CN102164888B (zh) 2015-06-03
IL210804A (en) 2015-06-30
RU2515611C2 (ru) 2014-05-20
US20130331455A1 (en) 2013-12-12
US8440716B2 (en) 2013-05-14
KR101708946B1 (ko) 2017-02-21
CN102164888A (zh) 2011-08-24
WO2010011296A2 (fr) 2010-01-28
IL210804A0 (en) 2011-04-28
EP2321264B1 (fr) 2016-05-04
US9434686B2 (en) 2016-09-06
RU2011106799A (ru) 2012-08-27
KR20110046484A (ko) 2011-05-04
US20110172303A1 (en) 2011-07-14
CA2731730A1 (fr) 2010-01-28
AU2009274549A1 (en) 2010-01-28
EP2321264A4 (fr) 2011-09-21
EP2321264A2 (fr) 2011-05-18
JP2011529048A (ja) 2011-12-01
AU2009274549B2 (en) 2014-05-01
JP5665740B2 (ja) 2015-02-04
WO2010011296A3 (fr) 2010-04-22
JP2014101380A (ja) 2014-06-05

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