HK1160012A1 - Monoclonal antibodies to fibroblast growth factor receptor - Google Patents

Monoclonal antibodies to fibroblast growth factor receptor

Info

Publication number
HK1160012A1
HK1160012A1 HK12100557.1A HK12100557A HK1160012A1 HK 1160012 A1 HK1160012 A1 HK 1160012A1 HK 12100557 A HK12100557 A HK 12100557A HK 1160012 A1 HK1160012 A1 HK 1160012A1
Authority
HK
Hong Kong
Prior art keywords
growth factor
monoclonal antibodies
factor receptor
fibroblast growth
fibroblast
Prior art date
Application number
HK12100557.1A
Other languages
English (en)
Chinese (zh)
Inventor
Kyung Jin Kim
Wei-Meng Zhao
Hangil Park
Maximiliano Vasquez
Original Assignee
Galaxy Biotech Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Galaxy Biotech Llc filed Critical Galaxy Biotech Llc
Publication of HK1160012A1 publication Critical patent/HK1160012A1/xx

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2863Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for growth factors, growth regulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57484Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
    • G01N33/57492Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites involving compounds localized on the membrane of tumor or cancer cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/33Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/51Complete heavy chain or Fd fragment, i.e. VH + CH1
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565Complementarity determining region [CDR]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/90Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705Assays involving receptors, cell surface antigens or cell surface determinants
    • G01N2333/71Assays involving receptors, cell surface antigens or cell surface determinants for growth factors; for growth regulators

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Hospice & Palliative Care (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
HK12100557.1A 2008-11-07 2012-01-17 Monoclonal antibodies to fibroblast growth factor receptor HK1160012A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US11268608P 2008-11-07 2008-11-07
US16487009P 2009-03-30 2009-03-30
PCT/US2009/063647 WO2010054265A2 (en) 2008-11-07 2009-11-06 Monoclonal antibodies to fibroblast growth factor receptor 2

Publications (1)

Publication Number Publication Date
HK1160012A1 true HK1160012A1 (en) 2012-08-10

Family

ID=42153600

Family Applications (3)

Application Number Title Priority Date Filing Date
HK12100557.1A HK1160012A1 (en) 2008-11-07 2012-01-17 Monoclonal antibodies to fibroblast growth factor receptor
HK15108641.9A HK1207974A1 (en) 2008-11-07 2015-09-04 Monoclonal antibodies to fibroblast growth factor receptor
HK18108939.7A HK1249053A1 (zh) 2008-11-07 2018-07-10 成纖維細胞生長因子受體2的單克隆抗體

Family Applications After (2)

Application Number Title Priority Date Filing Date
HK15108641.9A HK1207974A1 (en) 2008-11-07 2015-09-04 Monoclonal antibodies to fibroblast growth factor receptor
HK18108939.7A HK1249053A1 (zh) 2008-11-07 2018-07-10 成纖維細胞生長因子受體2的單克隆抗體

Country Status (21)

Country Link
US (8) US8101723B2 (de)
EP (4) EP2365828B1 (de)
JP (7) JP5627591B2 (de)
KR (1) KR101699432B1 (de)
CN (1) CN102131524B (de)
AU (1) AU2009313357B2 (de)
BR (1) BRPI0917315B8 (de)
CA (2) CA3166399A1 (de)
DK (3) DK3290052T3 (de)
ES (3) ES2770134T3 (de)
HK (3) HK1160012A1 (de)
HR (2) HRP20171640T1 (de)
HU (1) HUE035700T2 (de)
LT (2) LT3290052T (de)
MX (1) MX2011000455A (de)
NO (1) NO2842573T3 (de)
PL (3) PL2365828T3 (de)
PT (3) PT2842573T (de)
RU (1) RU2546254C9 (de)
SI (2) SI2842573T1 (de)
WO (1) WO2010054265A2 (de)

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Also Published As

Publication number Publication date
JP2019052165A (ja) 2019-04-04
HK1207974A1 (en) 2016-02-19
US9834609B2 (en) 2017-12-05
US20200347141A1 (en) 2020-11-05
CA3166399A1 (en) 2010-05-14
CA2733668C (en) 2022-08-30
CN102131524A (zh) 2011-07-20
EP2365828A4 (de) 2012-06-06
PL3290052T3 (pl) 2020-06-29
EP3290052B1 (de) 2019-12-25
US20230242650A1 (en) 2023-08-03
DK3290052T3 (da) 2020-02-03
NO2842573T3 (de) 2018-02-24
EP3290052A1 (de) 2018-03-07
AU2009313357A1 (en) 2010-05-14
EP2365828A2 (de) 2011-09-21
BRPI0917315A2 (pt) 2015-11-17
US20160362496A1 (en) 2016-12-15
US8603987B2 (en) 2013-12-10
JP2017019807A (ja) 2017-01-26
CN102131524B (zh) 2014-05-14
JP2022008996A (ja) 2022-01-14
JP7301106B2 (ja) 2023-06-30
JP5627591B2 (ja) 2014-11-19
SI2842573T1 (en) 2018-01-31
KR20110081141A (ko) 2011-07-13
US20100196364A1 (en) 2010-08-05
AU2009313357B2 (en) 2015-06-11
EP2842573A1 (de) 2015-03-04
EP3783024A1 (de) 2021-02-24
EP2365828B1 (de) 2014-10-15
JP6661734B2 (ja) 2020-03-11
ES2523740T3 (es) 2014-12-01
US20140193899A1 (en) 2014-07-10
PT3290052T (pt) 2020-02-06
ES2770134T3 (es) 2020-06-30
JP2023116746A (ja) 2023-08-22
LT3290052T (lt) 2020-02-25
US20190153105A1 (en) 2019-05-23
WO2010054265A3 (en) 2010-09-16
SI3290052T1 (sl) 2020-07-31
PT2842573T (pt) 2017-12-04
RU2011141890A (ru) 2013-04-27
EP2842573B1 (de) 2017-09-27
JP6342223B2 (ja) 2018-06-13
PL2365828T3 (pl) 2015-04-30
HRP20200090T1 (hr) 2020-04-03
HRP20171640T1 (hr) 2018-01-12
US20120134994A1 (en) 2012-05-31
MX2011000455A (es) 2011-02-25
RU2546254C9 (ru) 2015-07-10
PT2365828E (pt) 2014-12-12
US9382324B2 (en) 2016-07-05
LT2842573T (lt) 2017-12-11
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BRPI0917315B8 (pt) 2021-05-25
DK2365828T3 (en) 2014-12-08
CA2733668A1 (en) 2010-05-14
JP2012508184A (ja) 2012-04-05
US10689448B2 (en) 2020-06-23
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JP2014240385A (ja) 2014-12-25
WO2010054265A2 (en) 2010-05-14
RU2546254C2 (ru) 2015-04-10
KR101699432B1 (ko) 2017-01-24
US20180094063A1 (en) 2018-04-05
US8101723B2 (en) 2012-01-24
ES2646168T3 (es) 2017-12-12
JP2020096615A (ja) 2020-06-25
BRPI0917315B1 (pt) 2020-12-08
HK1249053A1 (zh) 2018-10-26
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US10138301B2 (en) 2018-11-27

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