HK1153152A1 - Use of epothilone d in treating tau-associated diseases including alzheimers disease d tau - Google Patents
Use of epothilone d in treating tau-associated diseases including alzheimers disease d tauInfo
- Publication number
- HK1153152A1 HK1153152A1 HK11107477.4A HK11107477A HK1153152A1 HK 1153152 A1 HK1153152 A1 HK 1153152A1 HK 11107477 A HK11107477 A HK 11107477A HK 1153152 A1 HK1153152 A1 HK 1153152A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- tau
- epothilone
- diseases including
- associated diseases
- treating
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/427—Thiazoles not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US4772908P | 2008-04-24 | 2008-04-24 | |
PCT/US2009/041634 WO2009132253A1 (en) | 2008-04-24 | 2009-04-24 | Use of epothelone d in treating tau-associated diseases including alzheimer's disease |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1153152A1 true HK1153152A1 (en) | 2012-03-23 |
Family
ID=40887113
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK11107477.4A HK1153152A1 (en) | 2008-04-24 | 2011-07-19 | Use of epothilone d in treating tau-associated diseases including alzheimers disease d tau |
Country Status (26)
Country | Link |
---|---|
US (3) | US20090270465A1 (es) |
EP (1) | EP2276485B1 (es) |
JP (1) | JP5548675B2 (es) |
KR (1) | KR20100137576A (es) |
CN (3) | CN104116736A (es) |
AR (1) | AR071598A1 (es) |
AU (1) | AU2009240538B2 (es) |
BR (1) | BRPI0911482A2 (es) |
CA (1) | CA2722371C (es) |
CL (1) | CL2009000990A1 (es) |
CY (1) | CY1115617T1 (es) |
DK (1) | DK2276485T3 (es) |
EA (1) | EA021758B1 (es) |
ES (1) | ES2501565T3 (es) |
HK (1) | HK1153152A1 (es) |
HR (1) | HRP20140783T1 (es) |
HU (1) | HUE024506T2 (es) |
IL (1) | IL208926A0 (es) |
MX (1) | MX2010011209A (es) |
NZ (1) | NZ588555A (es) |
PL (1) | PL2276485T3 (es) |
PT (1) | PT2276485E (es) |
SI (1) | SI2276485T1 (es) |
TW (1) | TWI472329B (es) |
WO (1) | WO2009132253A1 (es) |
ZA (1) | ZA201007460B (es) |
Families Citing this family (21)
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US7645789B2 (en) | 2006-04-07 | 2010-01-12 | Vertex Pharmaceuticals Incorporated | Indole derivatives as CFTR modulators |
PT2007756E (pt) | 2006-04-07 | 2015-11-02 | Vertex Pharma | Modeladores de transportadores de cassetes de ligação de atp |
US10022352B2 (en) | 2006-04-07 | 2018-07-17 | Vertex Pharmaceuticals Incorporated | Modulators of ATP-binding cassette transporters |
US8563573B2 (en) | 2007-11-02 | 2013-10-22 | Vertex Pharmaceuticals Incorporated | Azaindole derivatives as CFTR modulators |
WO2008112525A2 (en) * | 2007-03-09 | 2008-09-18 | Link Medicine Corporation | Treatment of lysosomal storage diseases |
WO2009151683A2 (en) | 2008-03-12 | 2009-12-17 | Link Medicine Corporation | Quinolinone farnesyl transferase inhibitors for the treatment of synucleinopathies and other indications |
NZ588555A (en) | 2008-04-24 | 2012-06-29 | Bristol Myers Squibb Co | Use of epothilone d in treating tau-associated diseases including alzheimer's disease |
WO2010057006A1 (en) | 2008-11-13 | 2010-05-20 | Link Medicine Corporation | Azaquinolinone derivatives and uses thereof |
US20110294794A1 (en) * | 2008-11-13 | 2011-12-01 | Link Medicine Corporation | Treatment of proteinopathies using a farnesyl transferase inhibitor |
US8802868B2 (en) | 2010-03-25 | 2014-08-12 | Vertex Pharmaceuticals Incorporated | Solid forms of (R)-1(2,2-difluorobenzo[D][1,3]dioxo1-5-yl)-N-(1-(2,3-dihydroxypropyl-6-fluoro-2-(1-hydroxy-2-methylpropan2-yl)-1H-Indol-5-yl)-Cyclopropanecarboxamide |
EP3381899B1 (en) | 2010-04-22 | 2021-01-06 | Vertex Pharmaceuticals Incorporated | Intermediate compound for process of producing cycloalkylcarboxamido-indole compounds |
US8563593B2 (en) * | 2010-06-08 | 2013-10-22 | Vertex Pharmaceuticals Incorporated | Formulations of (R)-1-(2,2-difluorobenzo[D] [1,3] dioxol-5-yl)-N-(1-(2,3-dihydroxypropyl)-6-fluoro-2-(1-hydroxy-2-methylpropan-2-yl)-1H-indol-5-yl)cyclopropanecarboxamide |
EP2811980A4 (en) * | 2012-01-31 | 2015-12-23 | Cerulean Pharma Inc | POLYMER-AGENT CONJUGATES, PARTICLES, COMPOSITIONS AND METHODS OF USE THEREOF |
US9834596B2 (en) | 2012-07-03 | 2017-12-05 | Washington University | Antibodies to tau |
EP2872122A1 (en) | 2012-07-16 | 2015-05-20 | Vertex Pharmaceuticals Incorporated | Pharmaceutical compositions of (r)-1-(2,2-diflurorbenzo[d][1,3]dioxol-5-yl)-n-(1-(2,3-dihydroxypropyl)-6-fluoro-2-(1-hydroxy-2-methylpropan-2-yl)-1h-indol-5-yl) cyclopropanecarboxamide and administration thereof |
HRP20230709T1 (hr) | 2014-04-15 | 2023-10-13 | Vertex Pharmaceuticals Incorporated | Farmaceutski pripravci za liječenje bolesti povezanih s regulatorom provodljivosti transmembrane cistične fibroze |
TW202136296A (zh) | 2014-06-27 | 2021-10-01 | 美商C2N醫療診斷有限責任公司 | 人類化抗-tau抗體 |
JP6321521B2 (ja) | 2014-11-04 | 2018-05-09 | Well Stone 有限会社 | タウ蛋白産生促進剤、タウ蛋白の欠乏に起因する疾患の治療薬・予防薬および治療用・予防用食品組成物 |
BR112019000098A2 (pt) | 2016-07-14 | 2019-04-09 | Bioarctic Ab | proteína de fornecimento ao cérebro, método de tratamento e/ou profilaxia de distúrbios cerebrais em mamíferos que possuem ou encontram-se em risco de desenvolver o mencionado distúrbio e método de diagnóstico e/ou detecção de distúrbios cerebrais em mamíferos suspeitos de possuir ou que se encontram em risco de desenvolver o mencionado distúrbio |
CN114727995A (zh) * | 2020-09-02 | 2022-07-08 | 北京华昊中天生物医药股份有限公司 | 优替德隆的固体口服制剂 |
CN113005086B (zh) * | 2021-02-01 | 2022-10-28 | 中国科学院遗传与发育生物学研究所 | 埃博霉素D和Apol8在调控神经干细胞定向神经元分化中的应用 |
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2009
- 2009-04-24 NZ NZ588555A patent/NZ588555A/en unknown
- 2009-04-24 AR ARP090101472A patent/AR071598A1/es unknown
- 2009-04-24 HU HUE09735906A patent/HUE024506T2/en unknown
- 2009-04-24 EP EP09735906.1A patent/EP2276485B1/en active Active
- 2009-04-24 KR KR1020107026208A patent/KR20100137576A/ko not_active Application Discontinuation
- 2009-04-24 EA EA201001695A patent/EA021758B1/ru not_active IP Right Cessation
- 2009-04-24 DK DK09735906.1T patent/DK2276485T3/da active
- 2009-04-24 TW TW98113762A patent/TWI472329B/zh not_active IP Right Cessation
- 2009-04-24 PL PL09735906T patent/PL2276485T3/pl unknown
- 2009-04-24 WO PCT/US2009/041634 patent/WO2009132253A1/en active Application Filing
- 2009-04-24 SI SI200931008T patent/SI2276485T1/sl unknown
- 2009-04-24 BR BRPI0911482A patent/BRPI0911482A2/pt not_active IP Right Cessation
- 2009-04-24 CA CA2722371A patent/CA2722371C/en not_active Expired - Fee Related
- 2009-04-24 MX MX2010011209A patent/MX2010011209A/es active IP Right Grant
- 2009-04-24 CL CL2009000990A patent/CL2009000990A1/es unknown
- 2009-04-24 ES ES09735906.1T patent/ES2501565T3/es active Active
- 2009-04-24 CN CN201410305166.4A patent/CN104116736A/zh active Pending
- 2009-04-24 PT PT97359061T patent/PT2276485E/pt unknown
- 2009-04-24 AU AU2009240538A patent/AU2009240538B2/en not_active Ceased
- 2009-04-24 CN CN201510082526.3A patent/CN104666297A/zh active Pending
- 2009-04-24 US US12/429,492 patent/US20090270465A1/en not_active Abandoned
- 2009-04-24 CN CN2009801242965A patent/CN102076339A/zh active Pending
- 2009-04-24 JP JP2011506476A patent/JP5548675B2/ja not_active Expired - Fee Related
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2010
- 2010-10-19 ZA ZA2010/07460A patent/ZA201007460B/en unknown
- 2010-10-25 IL IL208926A patent/IL208926A0/en unknown
-
2011
- 2011-06-01 US US13/150,671 patent/US8673949B2/en active Active
- 2011-07-19 HK HK11107477.4A patent/HK1153152A1/xx not_active IP Right Cessation
-
2014
- 2014-01-23 US US14/162,286 patent/US20140135367A1/en not_active Abandoned
- 2014-08-19 HR HRP20140783AT patent/HRP20140783T1/hr unknown
- 2014-10-10 CY CY20141100830T patent/CY1115617T1/el unknown
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