SI2276485T1 - Uporaba epotilona D pri zdravljenju Tau- povezanih bolezni, vključno z Alzheimerjevo boleznijo - Google Patents

Uporaba epotilona D pri zdravljenju Tau- povezanih bolezni, vključno z Alzheimerjevo boleznijo

Info

Publication number
SI2276485T1
SI2276485T1 SI200931008T SI200931008T SI2276485T1 SI 2276485 T1 SI2276485 T1 SI 2276485T1 SI 200931008 T SI200931008 T SI 200931008T SI 200931008 T SI200931008 T SI 200931008T SI 2276485 T1 SI2276485 T1 SI 2276485T1
Authority
SI
Slovenia
Prior art keywords
epothilone
disease
diseases including
associated diseases
including alzheimer
Prior art date
Application number
SI200931008T
Other languages
English (en)
Inventor
Charles F. Albright
Donna Marie Barten
Francis Y. Lee
Original Assignee
Bristol-Myers Squibb Company
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=40887113&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SI2276485(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Bristol-Myers Squibb Company filed Critical Bristol-Myers Squibb Company
Publication of SI2276485T1 publication Critical patent/SI2276485T1/sl

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425Thiazoles
    • A61K31/427Thiazoles not condensed and containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/06Antiglaucoma agents or miotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
SI200931008T 2008-04-24 2009-04-24 Uporaba epotilona D pri zdravljenju Tau- povezanih bolezni, vključno z Alzheimerjevo boleznijo SI2276485T1 (sl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US4772908P 2008-04-24 2008-04-24
EP09735906.1A EP2276485B1 (en) 2008-04-24 2009-04-24 Use of epothilone d in treating tau-associated diseases including alzheimer's disease
PCT/US2009/041634 WO2009132253A1 (en) 2008-04-24 2009-04-24 Use of epothelone d in treating tau-associated diseases including alzheimer's disease

Publications (1)

Publication Number Publication Date
SI2276485T1 true SI2276485T1 (sl) 2014-10-30

Family

ID=40887113

Family Applications (1)

Application Number Title Priority Date Filing Date
SI200931008T SI2276485T1 (sl) 2008-04-24 2009-04-24 Uporaba epotilona D pri zdravljenju Tau- povezanih bolezni, vključno z Alzheimerjevo boleznijo

Country Status (26)

Country Link
US (3) US20090270465A1 (sl)
EP (1) EP2276485B1 (sl)
JP (1) JP5548675B2 (sl)
KR (1) KR20100137576A (sl)
CN (3) CN102076339A (sl)
AR (1) AR071598A1 (sl)
AU (1) AU2009240538B2 (sl)
BR (1) BRPI0911482A2 (sl)
CA (1) CA2722371C (sl)
CL (1) CL2009000990A1 (sl)
CY (1) CY1115617T1 (sl)
DK (1) DK2276485T3 (sl)
EA (1) EA021758B1 (sl)
ES (1) ES2501565T3 (sl)
HK (1) HK1153152A1 (sl)
HR (1) HRP20140783T1 (sl)
HU (1) HUE024506T2 (sl)
IL (1) IL208926A0 (sl)
MX (1) MX2010011209A (sl)
NZ (1) NZ588555A (sl)
PL (1) PL2276485T3 (sl)
PT (1) PT2276485E (sl)
SI (1) SI2276485T1 (sl)
TW (1) TWI472329B (sl)
WO (1) WO2009132253A1 (sl)
ZA (1) ZA201007460B (sl)

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US10022352B2 (en) 2006-04-07 2018-07-17 Vertex Pharmaceuticals Incorporated Modulators of ATP-binding cassette transporters
US8563573B2 (en) 2007-11-02 2013-10-22 Vertex Pharmaceuticals Incorporated Azaindole derivatives as CFTR modulators
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WO2009151683A2 (en) 2008-03-12 2009-12-17 Link Medicine Corporation Quinolinone farnesyl transferase inhibitors for the treatment of synucleinopathies and other indications
CA2722371C (en) 2008-04-24 2016-06-21 Bristol-Myers Squibb Company Use of epothelone d in treating tau-associated diseases including alzheimer's disease
AU2009313906A1 (en) * 2008-11-13 2010-05-20 Link Medicine Corporation Treatment of proteinopathies using a farnesyl transferase inhibitor
WO2010057006A1 (en) 2008-11-13 2010-05-20 Link Medicine Corporation Azaquinolinone derivatives and uses thereof
US8802868B2 (en) 2010-03-25 2014-08-12 Vertex Pharmaceuticals Incorporated Solid forms of (R)-1(2,2-difluorobenzo[D][1,3]dioxo1-5-yl)-N-(1-(2,3-dihydroxypropyl-6-fluoro-2-(1-hydroxy-2-methylpropan2-yl)-1H-Indol-5-yl)-Cyclopropanecarboxamide
CA3108488A1 (en) 2010-04-22 2011-10-27 Vertex Pharmaceuticals Incorporated Process of producing cycloalkylcarboxamido-indole compounds
US8563593B2 (en) * 2010-06-08 2013-10-22 Vertex Pharmaceuticals Incorporated Formulations of (R)-1-(2,2-difluorobenzo[D] [1,3] dioxol-5-yl)-N-(1-(2,3-dihydroxypropyl)-6-fluoro-2-(1-hydroxy-2-methylpropan-2-yl)-1H-indol-5-yl)cyclopropanecarboxamide
EP2811980A4 (en) * 2012-01-31 2015-12-23 Cerulean Pharma Inc POLYMER-AGENT CONJUGATES, PARTICLES, COMPOSITIONS AND METHODS OF USE THEREOF
EP2870176A4 (en) 2012-07-03 2016-09-28 Univ Washington ANTIBODIES DIRECTED AGAINST TAU
EP2872122A1 (en) 2012-07-16 2015-05-20 Vertex Pharmaceuticals Incorporated Pharmaceutical compositions of (r)-1-(2,2-diflurorbenzo[d][1,3]dioxol-5-yl)-n-(1-(2,3-dihydroxypropyl)-6-fluoro-2-(1-hydroxy-2-methylpropan-2-yl)-1h-indol-5-yl) cyclopropanecarboxamide and administration thereof
IL266286B2 (en) 2014-04-15 2023-11-01 Vertex Pharma Pharmaceutical preparations for the treatment of diseases related to cystic fibrosis transmembrane conductance regulator modulators
TWI734975B (zh) 2014-06-27 2021-08-01 美商C2N醫療診斷有限責任公司 人類化抗-tau抗體
JP6321521B2 (ja) 2014-11-04 2018-05-09 Well Stone 有限会社 タウ蛋白産生促進剤、タウ蛋白の欠乏に起因する疾患の治療薬・予防薬および治療用・予防用食品組成物
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Also Published As

Publication number Publication date
US8673949B2 (en) 2014-03-18
CA2722371A1 (en) 2009-10-29
HRP20140783T1 (hr) 2014-09-12
MX2010011209A (es) 2010-11-12
KR20100137576A (ko) 2010-12-30
CL2009000990A1 (es) 2010-10-15
EA201001695A1 (ru) 2011-08-30
ES2501565T3 (es) 2014-10-02
AU2009240538B2 (en) 2014-08-07
US20140135367A1 (en) 2014-05-15
WO2009132253A1 (en) 2009-10-29
TWI472329B (zh) 2015-02-11
CN104116736A (zh) 2014-10-29
IL208926A0 (en) 2011-01-31
TW200948360A (en) 2009-12-01
JP2011522782A (ja) 2011-08-04
CN102076339A (zh) 2011-05-25
NZ588555A (en) 2012-06-29
EA021758B1 (ru) 2015-08-31
CY1115617T1 (el) 2017-01-04
CN104666297A (zh) 2015-06-03
AR071598A1 (es) 2010-06-30
DK2276485T3 (da) 2014-10-13
PL2276485T3 (pl) 2014-12-31
AU2009240538A1 (en) 2009-10-29
US20090270465A1 (en) 2009-10-29
HK1153152A1 (en) 2012-03-23
CA2722371C (en) 2016-06-21
US20110230528A1 (en) 2011-09-22
HUE024506T2 (en) 2016-01-28
EP2276485A1 (en) 2011-01-26
ZA201007460B (en) 2012-03-28
PT2276485E (pt) 2014-10-20
BRPI0911482A2 (pt) 2017-08-29
JP5548675B2 (ja) 2014-07-16
EP2276485B1 (en) 2014-07-16

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