HK1152898A1 - Beta turn peptidomimetic cyclic compounds for treating dry eye - Google Patents
Beta turn peptidomimetic cyclic compounds for treating dry eyeInfo
- Publication number
- HK1152898A1 HK1152898A1 HK11107167.9A HK11107167A HK1152898A1 HK 1152898 A1 HK1152898 A1 HK 1152898A1 HK 11107167 A HK11107167 A HK 11107167A HK 1152898 A1 HK1152898 A1 HK 1152898A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- dry eye
- cyclic compounds
- treating dry
- beta turn
- peptidomimetic cyclic
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/04—Artificial tears; Irrigation solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/12—Cyclic peptides with only normal peptide bonds in the ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/12—Cyclic peptides with only normal peptide bonds in the ring
- C07K5/123—Tripeptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Ophthalmology & Optometry (AREA)
- Heart & Thoracic Surgery (AREA)
- Urology & Nephrology (AREA)
- Cardiology (AREA)
- Vascular Medicine (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US12303608P | 2008-04-04 | 2008-04-04 | |
US20887309P | 2009-02-27 | 2009-02-27 | |
PCT/US2009/002121 WO2009123761A1 (fr) | 2008-04-04 | 2009-04-03 | Composés cycliques peptidomimétiques à spire bêta utilisés pour traiter l'œil sec |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1152898A1 true HK1152898A1 (en) | 2012-03-16 |
Family
ID=40897413
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK11107167.9A HK1152898A1 (en) | 2008-04-04 | 2011-07-11 | Beta turn peptidomimetic cyclic compounds for treating dry eye |
Country Status (10)
Country | Link |
---|---|
US (4) | US8293713B2 (fr) |
EP (1) | EP2271337B1 (fr) |
JP (2) | JP5480242B2 (fr) |
KR (1) | KR101565185B1 (fr) |
CN (1) | CN102046166B (fr) |
AU (1) | AU2009232352B2 (fr) |
CA (1) | CA2720141C (fr) |
ES (1) | ES2521515T3 (fr) |
HK (1) | HK1152898A1 (fr) |
WO (1) | WO2009123761A1 (fr) |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102046166B (zh) | 2008-04-04 | 2012-10-17 | 米梅托根药物公司 | 用于治疗干眼症的β-转角模拟肽环状化合物 |
CN104619717B (zh) * | 2012-06-22 | 2019-04-02 | 米梅奥亨制药公司 | β-转角模拟肽环状化合物的合成 |
KR20150004652A (ko) | 2013-07-03 | 2015-01-13 | 삼성디스플레이 주식회사 | 표시 패널, 이를 포함하는 표시 장치 및 이를 이용하는 영상 표시 방법 |
JP6267003B2 (ja) * | 2014-02-27 | 2018-01-24 | 参天製薬株式会社 | ジクアホソルまたはその塩およびレバミピドまたはその塩を組み合わせたことを特徴とする涙液分泌促進剤 |
CN113230021A (zh) | 2015-01-12 | 2021-08-10 | 科达莱昂治疗公司 | 微滴递送设备和方法 |
EP3253433A4 (fr) | 2015-04-10 | 2018-08-22 | Kedalion Therapeutics, Inc. | Distributeur piézoélectrique avec ampoule remplaçable |
CA2991661A1 (fr) | 2015-07-09 | 2017-01-12 | Mimetogen Pharmaceuticals, Inc. | Synthese en phase de solution et cristallisation de sels cycliques peptidomimetiques a coude beta |
KR101718733B1 (ko) | 2015-08-21 | 2017-03-22 | 국제약품 주식회사 | 레바미피드의 가용화 방법 및 이에 의해 제조된 안구건조증 치료용 액제 |
JP2019507193A (ja) | 2016-03-04 | 2019-03-14 | ジェームズ・エム・ライナーソン | 細菌のバイオフィルム形成を阻止又は妨害することによって眼障害を治療する方法 |
CA3039106A1 (fr) | 2017-01-20 | 2018-07-26 | Kedalion Therapeutics, Inc. | Distributeur de fluide piezoelectrique |
WO2019113483A1 (fr) | 2017-12-08 | 2019-06-13 | Kedalion Therapeutics, Inc. | Système d'alignement pour administration de fluide |
CN110092799B (zh) * | 2018-01-29 | 2021-11-12 | 广州丹康医药生物有限公司 | 一种环状化合物、其制备方法和应用 |
US12097145B2 (en) | 2019-03-06 | 2024-09-24 | Bausch + Lomb Ireland Limited | Vented multi-dose ocular fluid delivery system |
US11679028B2 (en) | 2019-03-06 | 2023-06-20 | Novartis Ag | Multi-dose ocular fluid delivery system |
US11925577B2 (en) | 2020-04-17 | 2024-03-12 | Bausch + Lomb Ireland Limted | Hydrodynamically actuated preservative free dispensing system |
US11938057B2 (en) | 2020-04-17 | 2024-03-26 | Bausch + Lomb Ireland Limited | Hydrodynamically actuated preservative free dispensing system |
WO2021212038A1 (fr) | 2020-04-17 | 2021-10-21 | Kedalion Therapeutics, Inc. | Système de distribution sans conservateur à actionnement hydrodynamique comprenant un réservoir de liquide pliable |
JP2024520670A (ja) * | 2021-06-02 | 2024-05-24 | ザ テキサス エーアンドエム ユニヴァーシティ システム | Trk受容体の選択的小分子アゴニスト及び部分アゴニスト |
KR20240108412A (ko) * | 2021-10-20 | 2024-07-09 | 스텔스 바이오테라퓨틱스 인코포레이티드 | 안과 병태를 치료하거나, 예방하거나, 억제하거나, 경감하거나 발병을 지연시키기 위한 방법 및 펩타이드 모방체를 포함하는 조성물 |
WO2023069255A1 (fr) * | 2021-10-20 | 2023-04-27 | Stealth Biotherapeutics Inc. | Procédés et compositions comprenant des peptidomimétiques pour le traitement, la prévention, l'inhibition, l'amélioration ou le retardement de l'apparition d'affections ophtalmiques |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB8917217D0 (en) * | 1989-07-27 | 1989-09-13 | Smith & Nephew | Ophthalmic compositions |
US5545617A (en) | 1993-11-12 | 1996-08-13 | The Schepens Eye Research Institute, Inc. | Therapeutic regulation of abnormal conjunctival goblet cell mucous secretion |
KR20010033484A (ko) * | 1997-12-22 | 2001-04-25 | 휴먼 게놈 사이언시즈, 인크. | 각질세포 성장 인자-2 제제 |
JP2001064198A (ja) | 1999-08-24 | 2001-03-13 | Teika Seiyaku Kk | 角膜疾患治療剤 |
ATE340571T1 (de) | 2000-01-18 | 2006-10-15 | Univ Mcgill | Pharmazeutische zubereitungen enthaltend beta- turn peptidomimetische zyklische substanzen |
ATE423135T1 (de) | 2005-06-13 | 2009-03-15 | Primm Srl | Heterodimere peptide mit ngf aktivität und deren verwendung zur behandlung von neurodegenerativen krankheiten |
EP1921087A1 (fr) | 2006-11-10 | 2008-05-14 | Primm S.R.L. | Procede de preparation des peptides cycliques |
CA2671613C (fr) | 2006-12-05 | 2018-07-03 | The Royal Institution For The Advancement Of Learning/Mcgill University | Procedes d'utilisation de modulateurs de recepteur trk |
CN102046166B (zh) | 2008-04-04 | 2012-10-17 | 米梅托根药物公司 | 用于治疗干眼症的β-转角模拟肽环状化合物 |
AU2010217889B2 (en) * | 2009-02-27 | 2014-12-18 | Mimetogen Pharmaceuticals Inc. | Peptidomimetic cyclic compounds for treating retinitis pigmentosa |
CN104619717B (zh) * | 2012-06-22 | 2019-04-02 | 米梅奥亨制药公司 | β-转角模拟肽环状化合物的合成 |
-
2009
- 2009-04-03 CN CN2009801190689A patent/CN102046166B/zh active Active
- 2009-04-03 AU AU2009232352A patent/AU2009232352B2/en active Active
- 2009-04-03 ES ES09726969.0T patent/ES2521515T3/es active Active
- 2009-04-03 WO PCT/US2009/002121 patent/WO2009123761A1/fr active Application Filing
- 2009-04-03 US US12/935,217 patent/US8293713B2/en active Active
- 2009-04-03 JP JP2011502992A patent/JP5480242B2/ja active Active
- 2009-04-03 EP EP09726969.0A patent/EP2271337B1/fr active Active
- 2009-04-03 CA CA2720141A patent/CA2720141C/fr active Active
- 2009-04-03 KR KR1020107024714A patent/KR101565185B1/ko active IP Right Grant
-
2011
- 2011-07-11 HK HK11107167.9A patent/HK1152898A1/xx unknown
-
2012
- 2012-08-31 US US13/601,258 patent/US8748391B2/en active Active
-
2014
- 2014-02-13 JP JP2014025563A patent/JP5870348B2/ja active Active
- 2014-05-29 US US14/290,845 patent/US9156882B2/en active Active
-
2015
- 2015-09-18 US US14/858,874 patent/US9707267B2/en active Active
Also Published As
Publication number | Publication date |
---|---|
CN102046166B (zh) | 2012-10-17 |
EP2271337B1 (fr) | 2014-09-03 |
EP2271337A1 (fr) | 2011-01-12 |
CA2720141C (fr) | 2014-01-28 |
ES2521515T3 (es) | 2014-11-12 |
CN102046166A (zh) | 2011-05-04 |
AU2009232352B2 (en) | 2013-09-05 |
US20120322747A1 (en) | 2012-12-20 |
JP2014080447A (ja) | 2014-05-08 |
JP5870348B2 (ja) | 2016-02-24 |
US9707267B2 (en) | 2017-07-18 |
KR20110010712A (ko) | 2011-02-07 |
KR101565185B1 (ko) | 2015-11-02 |
US20160082072A1 (en) | 2016-03-24 |
US9156882B2 (en) | 2015-10-13 |
CA2720141A1 (fr) | 2009-10-08 |
US8748391B2 (en) | 2014-06-10 |
US8293713B2 (en) | 2012-10-23 |
JP5480242B2 (ja) | 2014-04-23 |
AU2009232352A1 (en) | 2009-10-08 |
JP2011516477A (ja) | 2011-05-26 |
WO2009123761A1 (fr) | 2009-10-08 |
US20140274910A1 (en) | 2014-09-18 |
US20110105410A1 (en) | 2011-05-05 |
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Legal Events
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CHRG | Changes in the register |
Free format text: ADDITION OF INVENTOR: SARAGOVI, URI, H. - 391/394 |