HK1152035A1 - Pyrrolopyridines as kinase inhibitors - Google Patents
Pyrrolopyridines as kinase inhibitorsInfo
- Publication number
- HK1152035A1 HK1152035A1 HK11106054.7A HK11106054A HK1152035A1 HK 1152035 A1 HK1152035 A1 HK 1152035A1 HK 11106054 A HK11106054 A HK 11106054A HK 1152035 A1 HK1152035 A1 HK 1152035A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- pyrrolopyridines
- kinase inhibitors
- kinase
- inhibitors
- Prior art date
Links
- 229940043355 kinase inhibitor Drugs 0.000 title 1
- 239000003757 phosphotransferase inhibitor Substances 0.000 title 1
- 150000005255 pyrrolopyridines Chemical class 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Pain & Pain Management (AREA)
- Oncology (AREA)
- Hospice & Palliative Care (AREA)
- Hematology (AREA)
- Heart & Thoracic Surgery (AREA)
- Psychiatry (AREA)
- Cardiology (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US5292608P | 2008-05-13 | 2008-05-13 | |
PCT/US2009/043691 WO2009140320A1 (en) | 2008-05-13 | 2009-05-13 | Pyrrolopyridines as kinase inhibitors |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1152035A1 true HK1152035A1 (en) | 2012-02-17 |
Family
ID=40810786
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK11106054.7A HK1152035A1 (en) | 2008-05-13 | 2011-06-14 | Pyrrolopyridines as kinase inhibitors |
HK16107983.6A HK1219950A1 (zh) | 2008-05-13 | 2016-07-08 | 作爲激酶抑制劑的吡咯並吡啶 |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK16107983.6A HK1219950A1 (zh) | 2008-05-13 | 2016-07-08 | 作爲激酶抑制劑的吡咯並吡啶 |
Country Status (30)
Country | Link |
---|---|
US (6) | US8178131B2 (es) |
EP (2) | EP2990407B1 (es) |
JP (2) | JP5703212B2 (es) |
KR (2) | KR101643426B1 (es) |
CN (3) | CN104926810B (es) |
AR (1) | AR071717A1 (es) |
AU (1) | AU2009246402B2 (es) |
BR (1) | BRPI0913580B8 (es) |
CA (1) | CA2724262C (es) |
CL (1) | CL2009001152A1 (es) |
CO (1) | CO6321244A2 (es) |
CR (1) | CR11803A (es) |
CY (1) | CY1116692T1 (es) |
DK (1) | DK2307409T3 (es) |
ES (1) | ES2552643T3 (es) |
HK (2) | HK1152035A1 (es) |
HR (1) | HRP20151018T1 (es) |
HU (1) | HUE026160T2 (es) |
IL (1) | IL209258A (es) |
MX (1) | MX2010012449A (es) |
NZ (1) | NZ589318A (es) |
PH (1) | PH12013501779B1 (es) |
PL (1) | PL2307409T3 (es) |
PT (1) | PT2307409E (es) |
RS (1) | RS54358B1 (es) |
RU (1) | RU2517194C2 (es) |
SI (1) | SI2307409T1 (es) |
TW (2) | TWI554512B (es) |
UA (1) | UA111933C2 (es) |
WO (1) | WO2009140320A1 (es) |
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EP2242755B1 (en) | 2008-01-08 | 2012-09-12 | Array Biopharma, Inc. | Pyrrolopyridines as kinase inhibitors |
CN101965347B (zh) | 2008-01-09 | 2013-01-02 | 阵列生物制药公司 | 作为激酶抑制剂的吡唑并吡啶 |
JP2009256298A (ja) * | 2008-03-26 | 2009-11-05 | Sumitomo Chemical Co Ltd | ピペリジン−3−イルカーバメート化合物の光学分割方法およびその中間体 |
AR071717A1 (es) | 2008-05-13 | 2010-07-07 | Array Biopharma Inc | Pirrolo[2,3-b]piridinas inhibidoras de quinasas chk1 y chk2,composiciones farmaceuticas que las contienen,proceso para prepararlas y uso de las mismas en el tratamiento y prevencion del cancer. |
US8481557B2 (en) * | 2009-04-11 | 2013-07-09 | Array Biopharma Inc. | Method of treatment using checkpoint kinase 1 inhibitors |
MX341368B (es) * | 2009-04-11 | 2016-08-17 | Array Biopharma Inc * | Inhibidores de la cinasa del punto de control 1 para potenciar agentes dañinos del adn. |
TWI466885B (zh) | 2009-07-31 | 2015-01-01 | Japan Tobacco Inc | 含氮螺環化合物及其醫藥用途 |
WO2011029043A1 (en) * | 2009-09-04 | 2011-03-10 | Biogen Idec Ma Inc. | Heteroaryl btk inhibitors |
SG187742A1 (en) | 2010-08-20 | 2013-03-28 | Hutchison Medipharma Ltd | Pyrrolopyrimidine compounds and uses thereof |
RU2017127088A (ru) * | 2010-11-16 | 2019-02-04 | Эррэй Биофарма Инк. | Комбинация ингибиторов чекпойнт-киназы 1 и ингибиторов киназы wee 1 |
MX339899B (es) | 2011-02-25 | 2016-06-16 | Array Biopharma Inc | Compuestos de triazolopiridina como inhibidores de pim cinasa. |
EP2702063A1 (en) | 2011-04-29 | 2014-03-05 | Amgen Inc. | Bicyclic pyridazine compounds as pim inhibitors |
GB201201566D0 (en) * | 2012-01-30 | 2012-03-14 | Vernalis R&D Ltd | New chemical compounds |
MY168958A (en) * | 2012-04-23 | 2019-01-28 | Genentech Inc | Intermediates and processes for preparing compounds |
WO2015013579A1 (en) | 2013-07-26 | 2015-01-29 | Update Pharma Inc. | Compositions to improve the therapeutic benefit of bisantrene |
CN105705499B (zh) * | 2013-08-22 | 2018-10-12 | 基因泰克公司 | 用于制备化合物的方法 |
WO2015027090A1 (en) * | 2013-08-22 | 2015-02-26 | Genentech, Inc. | Intermediates and processes for preparing compounds |
UA117032C2 (uk) * | 2013-09-25 | 2018-06-11 | Вертекс Фармасьютикалз Інкорпорейтед | Селективний інгібітор фосфатидилінозитол-3-кінази-гамма |
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CN112823036A (zh) | 2018-07-03 | 2021-05-18 | 艾福姆德尤股份有限公司 | 用于治疗与sting活性有关的疾病的化合物和组合物 |
CN108912032A (zh) * | 2018-08-13 | 2018-11-30 | 南通大学 | 一种(3s,4r)-4-甲基吡咯烷-3-基氨基甲醇叔丁酯盐酸盐的化学合成方法 |
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TW202043198A (zh) | 2019-01-17 | 2020-12-01 | 美商Ifm Due有限公司 | 用於治療與sting活性相關之病況的化合物及組合物 |
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EP2242755B1 (en) * | 2008-01-08 | 2012-09-12 | Array Biopharma, Inc. | Pyrrolopyridines as kinase inhibitors |
CN101965347B (zh) | 2008-01-09 | 2013-01-02 | 阵列生物制药公司 | 作为激酶抑制剂的吡唑并吡啶 |
AR071717A1 (es) * | 2008-05-13 | 2010-07-07 | Array Biopharma Inc | Pirrolo[2,3-b]piridinas inhibidoras de quinasas chk1 y chk2,composiciones farmaceuticas que las contienen,proceso para prepararlas y uso de las mismas en el tratamiento y prevencion del cancer. |
US8481557B2 (en) * | 2009-04-11 | 2013-07-09 | Array Biopharma Inc. | Method of treatment using checkpoint kinase 1 inhibitors |
US20140221370A1 (en) | 2010-07-09 | 2014-08-07 | Array Biopharma Inc. | Pyrrolopyridines as kinase inhibitors |
RU2017127088A (ru) | 2010-11-16 | 2019-02-04 | Эррэй Биофарма Инк. | Комбинация ингибиторов чекпойнт-киназы 1 и ингибиторов киназы wee 1 |
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2009
- 2009-05-12 AR ARP090101708A patent/AR071717A1/es active IP Right Grant
- 2009-05-12 CL CL2009001152A patent/CL2009001152A1/es unknown
- 2009-05-13 CN CN201510289964.7A patent/CN104926810B/zh not_active Expired - Fee Related
- 2009-05-13 EP EP15175131.0A patent/EP2990407B1/en active Active
- 2009-05-13 KR KR1020107027941A patent/KR101643426B1/ko active IP Right Grant
- 2009-05-13 KR KR1020147015705A patent/KR101657856B1/ko active IP Right Grant
- 2009-05-13 SI SI200931284T patent/SI2307409T1/sl unknown
- 2009-05-13 WO PCT/US2009/043691 patent/WO2009140320A1/en active Application Filing
- 2009-05-13 UA UAA201015012A patent/UA111933C2/uk unknown
- 2009-05-13 PL PL09747404T patent/PL2307409T3/pl unknown
- 2009-05-13 NZ NZ589318A patent/NZ589318A/en not_active IP Right Cessation
- 2009-05-13 PT PT97474043T patent/PT2307409E/pt unknown
- 2009-05-13 HU HUE09747404A patent/HUE026160T2/en unknown
- 2009-05-13 EP EP09747404.3A patent/EP2307409B1/en active Active
- 2009-05-13 CN CN201910068067.1A patent/CN109942575A/zh active Pending
- 2009-05-13 AU AU2009246402A patent/AU2009246402B2/en not_active Ceased
- 2009-05-13 DK DK09747404.3T patent/DK2307409T3/en active
- 2009-05-13 BR BRPI0913580A patent/BRPI0913580B8/pt not_active IP Right Cessation
- 2009-05-13 MX MX2010012449A patent/MX2010012449A/es active IP Right Grant
- 2009-05-13 CN CN200980127299.4A patent/CN102089307B/zh not_active Expired - Fee Related
- 2009-05-13 JP JP2011509628A patent/JP5703212B2/ja not_active Expired - Fee Related
- 2009-05-13 RU RU2010150786/04A patent/RU2517194C2/ru active
- 2009-05-13 TW TW103133772A patent/TWI554512B/zh active
- 2009-05-13 TW TW098115906A patent/TWI458727B/zh active
- 2009-05-13 RS RS20150711A patent/RS54358B1/en unknown
- 2009-05-13 ES ES09747404.3T patent/ES2552643T3/es active Active
- 2009-05-13 US US12/992,468 patent/US8178131B2/en active Active
- 2009-05-13 CA CA2724262A patent/CA2724262C/en active Active
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2010
- 2010-11-11 IL IL209258A patent/IL209258A/en active IP Right Grant
- 2010-11-19 CR CR11803A patent/CR11803A/es unknown
- 2010-11-30 CO CO10150963A patent/CO6321244A2/es active IP Right Grant
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2011
- 2011-06-14 HK HK11106054.7A patent/HK1152035A1/xx not_active IP Right Cessation
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2012
- 2012-03-20 US US13/425,186 patent/US8545897B2/en active Active
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2013
- 2013-08-23 US US13/974,895 patent/US8758830B2/en active Active
- 2013-08-28 PH PH12013501779A patent/PH12013501779B1/en unknown
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2014
- 2014-05-06 US US14/271,129 patent/US8981085B2/en active Active
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2015
- 2015-01-07 US US14/591,691 patent/US9365568B2/en active Active
- 2015-02-23 JP JP2015032474A patent/JP2015098482A/ja not_active Withdrawn
- 2015-09-16 CY CY20151100812T patent/CY1116692T1/el unknown
- 2015-09-28 HR HRP20151018TT patent/HRP20151018T1/hr unknown
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2016
- 2016-01-05 US US14/988,521 patent/US9969727B2/en active Active
- 2016-07-08 HK HK16107983.6A patent/HK1219950A1/zh unknown
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PC | Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee) |
Effective date: 20230511 |