HK1148471A1 - Pegylation by dock and lock (dnl) technique (dnl) - Google Patents

Pegylation by dock and lock (dnl) technique (dnl)

Info

Publication number
HK1148471A1
HK1148471A1 HK11102652.2A HK11102652A HK1148471A1 HK 1148471 A1 HK1148471 A1 HK 1148471A1 HK 11102652 A HK11102652 A HK 11102652A HK 1148471 A1 HK1148471 A1 HK 1148471A1
Authority
HK
Hong Kong
Prior art keywords
dnl
pegylation
dock
lock
technique
Prior art date
Application number
HK11102652.2A
Other languages
English (en)
Chinese (zh)
Inventor
William Mcbride
Chien-Hsing Chang
Edmund Rossi
David Goldenberg
Original Assignee
Ibc Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ibc Pharmaceuticals Inc filed Critical Ibc Pharmaceuticals Inc
Publication of HK1148471A1 publication Critical patent/HK1148471A1/xx

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    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/68Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
    • A61K47/6835Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site
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    • BPERFORMING OPERATIONS; TRANSPORTING
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    • BPERFORMING OPERATIONS; TRANSPORTING
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    • CCHEMISTRY; METALLURGY
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HK11102652.2A 2007-10-26 2011-03-16 Pegylation by dock and lock (dnl) technique (dnl) HK1148471A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11/925,408 US7666400B2 (en) 2005-04-06 2007-10-26 PEGylation by the dock and lock (DNL) technique
PCT/US2008/081085 WO2009055653A1 (fr) 2007-10-26 2008-10-24 Pegylation par la technique d'accostage et verrouillage (dnl)

Publications (1)

Publication Number Publication Date
HK1148471A1 true HK1148471A1 (en) 2011-09-09

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HK11102652.2A HK1148471A1 (en) 2007-10-26 2011-03-16 Pegylation by dock and lock (dnl) technique (dnl)

Country Status (11)

Country Link
US (5) US7666400B2 (fr)
EP (1) EP2197468B1 (fr)
JP (2) JP5577558B2 (fr)
KR (1) KR101583388B1 (fr)
CN (1) CN101951939B (fr)
AU (1) AU2008316741B9 (fr)
CA (1) CA2696160C (fr)
HK (1) HK1148471A1 (fr)
IL (1) IL204066A (fr)
MX (1) MX2010004547A (fr)
WO (1) WO2009055653A1 (fr)

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US7534866B2 (en) * 2005-10-19 2009-05-19 Ibc Pharmaceuticals, Inc. Methods and compositions for generating bioactive assemblies of increased complexity and uses
US7666400B2 (en) * 2005-04-06 2010-02-23 Ibc Pharmaceuticals, Inc. PEGylation by the dock and lock (DNL) technique
US7550143B2 (en) * 2005-04-06 2009-06-23 Ibc Pharmaceuticals, Inc. Methods for generating stably linked complexes composed of homodimers, homotetramers or dimers of dimers and uses
ES2367891T3 (es) 2000-09-29 2011-11-10 Schering Corporation Interleucina-10 pegilada.
US20160279239A1 (en) 2011-05-02 2016-09-29 Immunomedics, Inc. Subcutaneous administration of anti-cd74 antibody for systemic lupus erythematosus and autoimmune disease
US8658773B2 (en) 2011-05-02 2014-02-25 Immunomedics, Inc. Ultrafiltration concentration of allotype selected antibodies for small-volume administration
US7906118B2 (en) 2005-04-06 2011-03-15 Ibc Pharmaceuticals, Inc. Modular method to prepare tetrameric cytokines with improved pharmacokinetics by the dock-and-lock (DNL) technology
US8551480B2 (en) 2004-02-13 2013-10-08 Immunomedics, Inc. Compositions and methods of use of immunotoxins comprising ranpirnase (Rap) show potent cytotoxic activity
US8435539B2 (en) * 2004-02-13 2013-05-07 Immunomedics, Inc. Delivery system for cytotoxic drugs by bispecific antibody pretargeting
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EP2197468A4 (fr) 2012-04-25
US20130177532A1 (en) 2013-07-11
IL204066A (en) 2015-06-30
US20090060862A1 (en) 2009-03-05
US20100261885A1 (en) 2010-10-14

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