HK1139658A1 - Benzimidazole derivatives - Google Patents

Benzimidazole derivatives

Info

Publication number
HK1139658A1
HK1139658A1 HK10105659.9A HK10105659A HK1139658A1 HK 1139658 A1 HK1139658 A1 HK 1139658A1 HK 10105659 A HK10105659 A HK 10105659A HK 1139658 A1 HK1139658 A1 HK 1139658A1
Authority
HK
Hong Kong
Prior art keywords
benzimidazole derivatives
mammals
compounds
treatment
cell growth
Prior art date
Application number
HK10105659.9A
Other languages
English (en)
Inventor
Christopher Scott Jones
GRECA Susan LA
Qifang Li
Michael John Munchhof
Lawrence Alan Reiter
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of HK1139658A1 publication Critical patent/HK1139658A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
HK10105659.9A 2007-06-29 2010-06-09 Benzimidazole derivatives HK1139658A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US94728707P 2007-06-29 2007-06-29
US4164508P 2008-04-02 2008-04-02
PCT/IB2008/001575 WO2009004427A2 (en) 2007-06-29 2008-06-16 Benzimidazole derivatives

Publications (1)

Publication Number Publication Date
HK1139658A1 true HK1139658A1 (en) 2010-09-24

Family

ID=40161351

Family Applications (1)

Application Number Title Priority Date Filing Date
HK10105659.9A HK1139658A1 (en) 2007-06-29 2010-06-09 Benzimidazole derivatives

Country Status (46)

Country Link
US (2) US8148401B2 (lt)
EP (1) EP2170860B9 (lt)
JP (2) JP4567099B2 (lt)
KR (1) KR101143246B1 (lt)
CN (1) CN101687841B (lt)
AP (1) AP2377A (lt)
AR (1) AR067346A1 (lt)
AU (1) AU2008272641B2 (lt)
BR (1) BRPI0813412B8 (lt)
CA (1) CA2690953C (lt)
CL (1) CL2008001922A1 (lt)
CO (1) CO6160232A2 (lt)
CR (1) CR11150A (lt)
CU (1) CU23847B1 (lt)
CY (2) CY1118650T1 (lt)
DK (1) DK2170860T5 (lt)
DO (1) DOP2009000278A (lt)
EA (1) EA016888B1 (lt)
EC (1) ECSP099803A (lt)
ES (1) ES2609258T3 (lt)
FR (1) FR20C1038I2 (lt)
GE (1) GEP20125702B (lt)
GT (1) GT200900328A (lt)
HK (1) HK1139658A1 (lt)
HN (1) HN2008000974A (lt)
HR (1) HRP20161562T2 (lt)
HU (2) HUE030052T4 (lt)
IL (1) IL202420A (lt)
LT (2) LT2170860T (lt)
MA (1) MA31466B1 (lt)
ME (1) ME00962B (lt)
MY (1) MY148636A (lt)
NI (1) NI200900219A (lt)
NL (1) NL301057I2 (lt)
NO (1) NO2020027I1 (lt)
NZ (1) NZ581889A (lt)
PA (1) PA8785401A1 (lt)
PE (2) PE20090772A1 (lt)
PL (1) PL2170860T3 (lt)
PT (1) PT2170860T (lt)
RS (1) RS55395B9 (lt)
SI (1) SI2170860T1 (lt)
TN (1) TN2009000544A1 (lt)
TW (1) TWI371451B (lt)
UY (1) UY31164A1 (lt)
WO (1) WO2009004427A2 (lt)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HUE030052T4 (en) * 2007-06-29 2017-06-28 Pfizer Benzimidazole derivatives
US9265734B2 (en) 2008-09-03 2016-02-23 Biomarin Pharmaceutical Inc. Compositions including 6-aminohexanoic acid derivatives as HDAC inhibitors
KR20120026534A (ko) * 2009-06-11 2012-03-19 시에나 바이오테크 에스.피.에이. 헤지호그 경로 길항제 및 그의 치료적 적용
JP5599802B2 (ja) 2009-08-26 2014-10-01 武田薬品工業株式会社 縮合複素環誘導体およびその用途
US10010439B2 (en) 2010-06-13 2018-07-03 Synerz Medical, Inc. Intragastric device for treating obesity
US8628554B2 (en) 2010-06-13 2014-01-14 Virender K. Sharma Intragastric device for treating obesity
US10420665B2 (en) 2010-06-13 2019-09-24 W. L. Gore & Associates, Inc. Intragastric device for treating obesity
US9526648B2 (en) 2010-06-13 2016-12-27 Synerz Medical, Inc. Intragastric device for treating obesity
CA2813162C (en) 2010-10-20 2015-06-16 Pfizer Inc. Pyridine-2- derivatives as smoothened receptor modulators
JP5452459B2 (ja) 2010-12-16 2014-03-26 株式会社Ｎｔｔドコモ ホーム基地局及びハンドオーバ方法
US10059723B2 (en) 2011-02-28 2018-08-28 Biomarin Pharmaceutical Inc. Histone deacetylase inhibitors
JP6250403B2 (ja) 2011-02-28 2017-12-20 バイオマリン ファーマシューティカル インク ヒストン脱アセチル化酵素阻害剤
US8957066B2 (en) 2011-02-28 2015-02-17 Biomarin Pharmaceutical Inc. Histone deacetylase inhibitors
US9051305B2 (en) 2011-03-08 2015-06-09 Eutropics Pharmaceuticals, Inc. Compositions and methods useful for treating diseases
FR2980477B1 (fr) 2011-09-23 2013-10-18 Centre Nat Rech Scient Nouveaux composes modulateurs de la voie de signalisation des proteines hedgehog, leurs formes marquees, et applications
JP6163156B2 (ja) * 2011-09-26 2017-07-12 メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツングＭｅｒｃｋ Ｐａｔｅｎｔ Ｇｅｓｅｌｌｓｃｈａｆｔ ｍｉｔ ｂｅｓｃｈｒａｅｎｋｔｅｒ Ｈａｆｔｕｎｇ リゾホスファチジン酸（ｌｐａ）受容体アンタゴニストとしてのベンジルピペリジン化合物
WO2013192423A2 (en) 2012-06-20 2013-12-27 Eutropics Pharmaceuticals, Inc. Methods and compositions useful for treating diseases involving bcl-2 family proteins with quinoline derivatives
WO2014081953A1 (en) 2012-11-21 2014-05-30 Richard David J Methods and compositions useful for treating diseases involving bcl-2 family proteins with isoquinoline and quinoline derivatives
CA2903490C (en) 2013-03-15 2021-04-13 Biomarin Pharmaceutical Inc. Hdac inhibitors
US10435364B2 (en) 2013-04-17 2019-10-08 Albert Ludwigs Universität Freiburg Compounds for use as bromodomain inhibitors
US10732182B2 (en) 2013-08-01 2020-08-04 Eutropics Pharmaceuticals, Inc. Method for predicting cancer sensitivity
GB2519344A (en) * 2013-10-18 2015-04-22 Redx Pharma Ltd Compounds
WO2015066305A1 (en) 2013-10-30 2015-05-07 Eutropics Pharmaceuticals, Inc. Methods for determining chemosensitivity and chemotoxicity
KR20190038677A (ko) * 2015-04-24 2019-04-08 화이자 인코포레이티드 1-((2r,4r)-2-(1h-벤조[d]이미다졸-2-일)-1-메틸피페리딘-4-일)-3-(4-시아노페닐)우레아 말레에이트의 결정질 형태
US10779980B2 (en) 2016-04-27 2020-09-22 Synerz Medical, Inc. Intragastric device for treating obesity
JP2020164722A (ja) * 2019-03-29 2020-10-08 デクセリアルズ株式会社 接着剤組成物
US20230107634A1 (en) 2020-01-28 2023-04-06 Teva Pharmaceuticals International Gmbh Processes for the preparation of glasdegib and salt thereof and solid state forms of glasdegib maleate and process for preparation thereof
CN113248475B (zh) * 2020-02-11 2023-03-17 中国科学院上海药物研究所 一类杂环取代的苯并咪唑二聚体或其药学上可接受的盐、组合物及其用途
WO2021191278A1 (en) 2020-03-26 2021-09-30 Lek Pharmaceuticals D.D. Dimaleate form of 1-((2r,4r)-2-(1h-benzo[d]imidazol-2-yl)-1-methylpiperidin-4-yl)-3-(4-cyanophenyl)urea
CN115997122A (zh) 2020-06-26 2023-04-21 拉夸里亚创药株式会社 类维生素a与癌治疗剂的组合疗法有效的癌患者的选择方法、及类维生素a与癌治疗剂的组合药物
WO2023002362A1 (en) 2021-07-22 2023-01-26 Pfizer Inc. Treatment of hematological malignancy

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL366799A1 (en) 2001-07-27 2005-02-07 Curis, Inc. Mediators of hedgehog signaling pathways, compositions and uses related thereto
HUP0402184A2 (hu) * 2001-12-04 2005-02-28 Actelion Pharmaceuticals Ltd. 4-(Piperidil- és pirrolidil-alkil-ureido)-kinolin-származékok mint urotenzin II receptor antagonisták és ezeket tartalmazó gyógyszerkészítmények
TW200304820A (en) 2002-03-25 2003-10-16 Avanir Pharmaceuticals Use of benzimidazole analogs in the treatment of cell proliferation
WO2004035549A1 (en) 2002-10-17 2004-04-29 Amgen Inc. Benzimidazole derivatives and their use as vanilloid receptor ligands
WO2005042495A1 (en) 2003-10-21 2005-05-12 Imclone Systems Incorporated (benzimidazol-2-yl)-phenyl-phenyl-urea compounds and methods for inhibiting heparanase activity
US7309716B2 (en) 2003-10-28 2007-12-18 Vertex Pharmaceuticals Incorporated Benzimidazoles useful as modulators of ion channels
WO2006050506A1 (en) * 2004-11-03 2006-05-11 Curis, Inc. Mediators of hedgehog signaling pathways, compositions and uses related thereto
DE102005012875B4 (de) 2005-03-19 2006-11-16 Sanofi-Aventis Deutschland Gmbh Verwendung von Amino substituierten 8-N-Benzimidazolen
WO2006124780A2 (en) * 2005-05-12 2006-11-23 Kalypsys, Inc. Ih-benzo [d] imidazole compounds as inhibitors of b-raf kinase
WO2008064830A1 (en) 2006-11-27 2008-06-05 Ucb Pharma, S.A. Bicyclic and heterobicyclic derivatives, processes for preparing them and their pharmaceutical uses
CA2672815A1 (en) 2006-12-15 2008-06-26 Pfizer Products Inc. Benzimidazole derivatives for use in treating abnormal cell growth
HUE030052T4 (en) 2007-06-29 2017-06-28 Pfizer Benzimidazole derivatives
EP2303275A4 (en) 2008-06-17 2012-05-09 Univ Duke STANDARD RECEPTOR MODULATORS
US8507491B2 (en) 2008-08-25 2013-08-13 Irm Llc Compounds and compositions as hedgehog pathway inhibitors

Also Published As

Publication number Publication date
HRP20161562T2 (hr) 2017-04-21
HN2008000974A (es) 2011-01-24
CO6160232A2 (es) 2010-05-20
HUE030052T4 (en) 2017-06-28
WO2009004427A3 (en) 2009-06-04
PT2170860T (pt) 2017-01-04
EA200971104A1 (ru) 2010-06-30
JP4567099B2 (ja) 2010-10-20
NL301057I2 (nl) 2020-09-10
CN101687841A (zh) 2010-03-31
TN2009000544A1 (fr) 2011-03-31
US8431597B2 (en) 2013-04-30
EP2170860B9 (en) 2017-02-22
KR101143246B1 (ko) 2012-05-18
MY148636A (en) 2013-05-15
DK2170860T5 (en) 2017-03-20
US8148401B2 (en) 2012-04-03
LT2170860T (lt) 2017-01-10
AR067346A1 (es) 2009-10-07
US20120157495A1 (en) 2012-06-21
IL202420A (en) 2014-05-28
LTC2170860I2 (lt) 2022-03-10
EP2170860B1 (en) 2016-11-02
ECSP099803A (es) 2010-01-29
MA31466B1 (fr) 2010-06-01
EA016888B1 (ru) 2012-08-30
FR20C1038I1 (lt) 2020-10-02
BRPI0813412A2 (pt) 2014-12-30
EP2170860A2 (en) 2010-04-07
NI200900219A (es) 2010-03-11
PE20090772A1 (es) 2009-06-24
JP2010531869A (ja) 2010-09-30
AP2377A (en) 2012-03-07
AU2008272641A1 (en) 2009-01-08
CY2020028I2 (el) 2020-11-25
CU23847B1 (es) 2012-10-15
HUE030052T2 (hu) 2017-04-28
PA8785401A1 (es) 2009-01-23
CN101687841B (zh) 2013-07-10
HRP20161562T1 (hr) 2016-12-30
IL202420A0 (en) 2010-06-30
AU2008272641B2 (en) 2013-08-29
CY2020028I1 (el) 2020-11-25
UY31164A1 (es) 2009-01-30
NZ581889A (en) 2011-05-27
BRPI0813412B8 (pt) 2021-05-25
GT200900328A (es) 2011-08-29
NL301057I1 (nl) 2020-07-22
CA2690953A1 (en) 2009-01-08
KR20100028120A (ko) 2010-03-11
TWI371451B (en) 2012-09-01
JP2010280693A (ja) 2010-12-16
TW200911792A (en) 2009-03-16
DK2170860T3 (en) 2017-01-09
NO2020027I1 (no) 2020-08-11
DOP2009000278A (es) 2009-12-31
GEP20125702B (en) 2012-12-10
HUS2000031I1 (hu) 2020-09-28
WO2009004427A2 (en) 2009-01-08
BRPI0813412B1 (pt) 2020-01-21
ES2609258T3 (es) 2017-04-19
PE20121010A1 (es) 2012-08-06
CL2008001922A1 (es) 2009-01-02
ME00962B (me) 2012-06-20
CA2690953C (en) 2012-10-02
RS55395B1 (sr) 2017-04-28
CR11150A (es) 2010-02-08
FR20C1038I2 (fr) 2021-08-13
PL2170860T3 (pl) 2017-05-31
CY1118650T1 (el) 2017-07-12
AP2009005089A0 (en) 2009-12-31
SI2170860T1 (sl) 2017-01-31
RS55395B9 (sr) 2020-01-31
US20090005416A1 (en) 2009-01-01
LTPA2020528I1 (lt) 2020-09-25
CU20090225A7 (es) 2012-02-15

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