HK1137509A1 - Circulating tumor cell assay - Google Patents

Circulating tumor cell assay

Info

Publication number
HK1137509A1
HK1137509A1 HK10100979.3A HK10100979A HK1137509A1 HK 1137509 A1 HK1137509 A1 HK 1137509A1 HK 10100979 A HK10100979 A HK 10100979A HK 1137509 A1 HK1137509 A1 HK 1137509A1
Authority
HK
Hong Kong
Prior art keywords
tumor cell
circulating tumor
cell assay
assay
circulating
Prior art date
Application number
HK10100979.3A
Other languages
English (en)
Chinese (zh)
Inventor
‧瓜爾貝托
‧羅伯茨
‧梅爾文
‧雷伯萊特
‧錢尼斯
‧康奈利
‧特斯塔潘
Original Assignee
輝瑞產品公司
維利迪克斯有限責任公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 輝瑞產品公司, 維利迪克斯有限責任公司 filed Critical 輝瑞產品公司
Publication of HK1137509A1 publication Critical patent/HK1137509A1/xx

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/502Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
    • G01N33/5023Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects on expression patterns
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5044Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
    • G01N33/5064Endothelial cells
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57484Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
    • G01N33/57492Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites involving compounds localized on the membrane of tumor or cancer cells
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57484Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
    • G01N33/57496Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites involving intracellular compounds
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/46Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
    • G01N2333/47Assays involving proteins of known structure or function as defined in the subgroups
    • G01N2333/4701Details
    • G01N2333/4742Keratin; Cytokeratin
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/46Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
    • G01N2333/47Assays involving proteins of known structure or function as defined in the subgroups
    • G01N2333/4701Details
    • G01N2333/4745Insulin-like growth factor binding protein
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705Assays involving receptors, cell surface antigens or cell surface determinants
    • G01N2333/71Assays involving receptors, cell surface antigens or cell surface determinants for growth factors; for growth regulators
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90Enzymes; Proenzymes
    • G01N2333/91Transferases (2.)
    • G01N2333/912Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • G01N2333/91205Phosphotransferases in general
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2458/00Labels used in chemical analysis of biological material
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/52Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02Column chromatography

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Cell Biology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Oncology (AREA)
  • Hospice & Palliative Care (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Toxicology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
HK10100979.3A 2006-06-02 2010-01-29 Circulating tumor cell assay HK1137509A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US81081106P 2006-06-02 2006-06-02
PCT/IB2007/001483 WO2007141626A1 (en) 2006-06-02 2007-05-29 Circulating tumor cell assay

Publications (1)

Publication Number Publication Date
HK1137509A1 true HK1137509A1 (en) 2010-07-30

Family

ID=38476880

Family Applications (1)

Application Number Title Priority Date Filing Date
HK10100979.3A HK1137509A1 (en) 2006-06-02 2010-01-29 Circulating tumor cell assay

Country Status (20)

Country Link
US (4) US8940493B2 (xx)
EP (1) EP2027470B1 (xx)
JP (1) JP4943504B2 (xx)
KR (3) KR20090023423A (xx)
CN (1) CN101600966B (xx)
AU (1) AU2007255110B8 (xx)
BR (1) BRPI0712225A8 (xx)
CA (1) CA2653745C (xx)
DK (1) DK2027470T3 (xx)
ES (1) ES2397971T3 (xx)
HK (1) HK1137509A1 (xx)
IL (1) IL195577A (xx)
MX (1) MX2008015425A (xx)
NZ (1) NZ573187A (xx)
PL (1) PL2027470T3 (xx)
PT (1) PT2027470E (xx)
RU (1) RU2429486C2 (xx)
SI (1) SI2027470T1 (xx)
WO (1) WO2007141626A1 (xx)
ZA (1) ZA200810203B (xx)

Families Citing this family (45)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2374450T3 (es) 2005-09-20 2012-02-16 OSI Pharmaceuticals, LLC Marcadores biológicos predictivos de respuesta anticancerígena para inhibidores de cinasa del receptor del factor de crecimiento 1 similar a insulina.
KR20090023423A (ko) 2006-06-02 2009-03-04 화이자 프로덕츠 인코포레이티드 순환 종양 세포 분석
PE20090368A1 (es) 2007-06-19 2009-04-28 Boehringer Ingelheim Int Anticuerpos anti-igf
CA2694154A1 (en) 2007-10-03 2009-04-09 Osi Pharmaceuticals, Inc. Biological markers predictive of anti-cancer response to insulin-like growth factor-1 receptor kinase inhibitors
AU2008307579A1 (en) 2007-10-03 2009-04-09 Osi Pharmaceuticals, Inc. Biological markers predictive of anti-cancer response to insulin-like growth factor-1 receptor kinase inhibitors
US20090258365A1 (en) 2008-03-25 2009-10-15 Terstappen Leon W M M METHOD FOR DETECTING IGF1R/Chr 15 in CIRCULATING TUMOR CELLS USING FISH
NZ592151A (en) 2008-12-12 2012-10-26 Boehringer Ingelheim Int Anti-igf antibodies
ES2661735T3 (es) * 2009-10-21 2018-04-03 The Scripps Research Institute Método para usar células no raras para detectar células raras
WO2011083391A2 (en) * 2010-01-05 2011-07-14 Pfizer Inc. Biomarkers for anti-igf-ir cancer therapy
BR112013009008A2 (pt) * 2010-10-14 2017-10-17 Veridex Llc métodos e kits para a detecção de células circulantes de tumor em pacientes pancreáticos com o uso de reagentes de detecção de captura e de coquetel poliespecíficos
AU2012209329A1 (en) * 2011-01-24 2013-09-12 Epic Sciences, Inc. Methods for obtaining single cells and applications of single cell omics
WO2012149014A1 (en) 2011-04-25 2012-11-01 OSI Pharmaceuticals, LLC Use of emt gene signatures in cancer drug discovery, diagnostics, and treatment
MX351113B (es) * 2011-07-21 2017-10-02 Janssen Diagnostics Llc Ensayo para capturar y detectar células circulantes de mieloma múltiple de la sangre.
US9535065B2 (en) * 2011-09-06 2017-01-03 Becton, Dickinson And Company Methods and compositions for cytometric detection of rare target cells in a sample
AU2013302867A1 (en) 2012-08-13 2015-02-26 The Regents Of The University Of California Methods and systems for detecting biological components
BR112015007528A2 (pt) * 2012-10-05 2018-09-04 Genentech Inc método para prever a resposta, para prever a responsividade, para identificar e para tratar um paciente que tem uma disfunção inflamatória gastrointestinal.
EP2912433B1 (en) * 2012-10-26 2019-03-20 Fluidigm Canada Inc. Cell analysis by mass cytometry
US9396532B2 (en) * 2012-11-15 2016-07-19 Siemens Healthcare Diagnostics, Inc. Cell feature-based automatic circulating tumor cell detection
JP6509745B2 (ja) 2013-01-25 2019-05-08 エックスセル・バイオサイエンシズ・インコーポレイテッド 標的細胞の選択的富化のための方法、組成物、キット、及びシステム
US20150233932A1 (en) * 2013-02-19 2015-08-20 Ching-Ping Tseng Methods, Systems, and Compositions for Enrichment of Rare Cells
US20140255413A1 (en) 2013-03-07 2014-09-11 Boehringer Ingelheim International Gmbh Combination therapy for neoplasia treatment
EP3060680B1 (en) 2013-10-21 2019-02-27 The General Hospital Corporation Methods relating to circulating tumor cell clusters and the treatment of cancer
CN103630440A (zh) * 2013-11-28 2014-03-12 武汉大学 一种循环肿瘤细胞的富集方法
WO2015112955A1 (en) 2014-01-27 2015-07-30 Epic Sciences, Inc. Circulating tumor cell diagnostics for prostate cancer biomarkers
US20160377624A1 (en) * 2014-02-05 2016-12-29 Fujirebio Diagnostics Ab Composition and method for detecting malignant neoplastic disease
WO2015127008A1 (en) 2014-02-21 2015-08-27 Epic Sciences, Inc. Methods for analyzing rare circulating cells
CN103940997B (zh) * 2014-03-21 2017-01-04 上海柏慧康生物科技有限公司 一种乳腺癌循环肿瘤细胞检测系统及试剂盒
KR101656037B1 (ko) * 2014-04-30 2016-09-08 울산과학기술원 희소 세포 분리장치, 희소 세포 분리 방법 및 이를 이용한 희소 세포 검출 방법
EP3160654A4 (en) 2014-06-27 2017-11-15 The Regents of The University of California Pcr-activated sorting (pas)
CN104345052B (zh) * 2014-09-29 2017-10-20 南通市肿瘤医院 一种荧光负染法检测活细胞的方法
EP3209419A4 (en) 2014-10-22 2018-10-03 The Regents of The University of California High definition microdroplet printer
EP3253479B1 (en) 2015-02-04 2022-09-21 The Regents of The University of California Sequencing of nucleic acids via barcoding in discrete entities
JP6746845B2 (ja) * 2015-04-22 2020-08-26 イミューノメディクス、インコーポレイテッドImmunomedics, Inc. 循環trop−2陽性癌細胞の単離、検出、診断及び/または特徴付け
KR101701618B1 (ko) 2015-06-23 2017-02-13 국립암센터 전도성 고분자를 이용한 세포 유리 dna 검출용 구조체 및 이의 용도
RU2616532C1 (ru) * 2015-12-28 2017-04-17 Федеральное государственное бюджетное учреждение "Ростовский научно-исследовательский онкологический институт" Министерства здравоохранения Российской Федерации Способ оценки чувствительности опухоли к проводимой химиотерапии больных местно-распространенным раком молочной железы
KR102130872B1 (ko) 2016-04-27 2020-07-06 주식회사 엘지화학 고체 시료의 수분 측정 장치, 고체 시료 수분 함량 측정 방법 및 이미드화율 분석 방법
WO2018031691A1 (en) 2016-08-10 2018-02-15 The Regents Of The University Of California Combined multiple-displacement amplification and pcr in an emulsion microdroplet
CA3047328A1 (en) 2016-12-21 2018-06-28 The Regents Of The University Of California Single cell genomic sequencing using hydrogel based droplets
US11576424B2 (en) 2017-04-05 2023-02-14 Altria Client Services Llc Susceptor for use with an inductively heated aerosol-generating device or system
KR102607651B1 (ko) 2017-04-05 2023-11-30 필립모리스 프로덕츠 에스.에이. 유도 가열식 에어로졸 발생 장치 또는 시스템과 함께 사용하기 위한 서셉터
US10501739B2 (en) 2017-10-18 2019-12-10 Mission Bio, Inc. Method, systems and apparatus for single cell analysis
EP3540631A1 (de) * 2018-03-15 2019-09-18 Siemens Healthcare GmbH In-vitro-verfahren zum markierungsfreien bestimmen eines zelltyps einer weissen blutzelle
CN109406245A (zh) * 2018-09-12 2019-03-01 中国辐射防护研究院 一种电子线照射对小鼠igf相关蛋白表达影响的检测方法
AU2020280104A1 (en) 2019-05-22 2022-01-20 Mission Bio, Inc. Method and apparatus for simultaneous targeted sequencing of DNA, RNA and protein
WO2021003255A1 (en) 2019-07-01 2021-01-07 Mission Bio Method and apparatus to normalize quantitative readouts in single-cell experiments

Family Cites Families (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4551435A (en) * 1983-08-24 1985-11-05 Immunicon, Inc. Selective removal of immunospecifically recognizable substances from solution
US4795698A (en) * 1985-10-04 1989-01-03 Immunicon Corporation Magnetic-polymer particles
US4925788A (en) * 1986-10-24 1990-05-15 Immunicon Corporation Immunoassay system and procedure based on precipitin-like interaction between immune complex and Clq or other non-immunospecific factor
US5108933A (en) * 1988-09-16 1992-04-28 Immunicon Corporation Manipulation of colloids for facilitating magnetic separations
US5200084A (en) * 1990-09-26 1993-04-06 Immunicon Corporation Apparatus and methods for magnetic separation
JP2000508171A (ja) * 1996-04-05 2000-07-04 ザ・ジョンズ・ホプキンス・ユニバーシティ・スクール・オブ・メディシン 希少細胞の富化方法
US20010018192A1 (en) * 1998-02-12 2001-08-30 Terstappen Leon W.M.M. Labeled cells for use as an internal functional control in rare cell detection assays
AU760560B2 (en) * 1998-02-12 2003-05-15 Board Of Regents, The University Of Texas System Methods and reagents for the rapid and efficient isolation of circulating cancer cells
US20020172987A1 (en) * 1998-02-12 2002-11-21 Terstappen Leon W.M.M. Methods and reagents for the rapid and efficient isolation of circulating cancer cells
CA2350692A1 (en) 1998-10-29 2000-05-11 Cell Works Inc. Multiple marker characterization of single cells
WO2000047998A1 (en) 1999-02-10 2000-08-17 Cell Works Inc. Class characterization of circulating cancer cells isolated from body fluids and methods of use
JP2001041959A (ja) * 1999-05-24 2001-02-16 Toray Ind Inc 癌細胞検出システムおよび癌細胞検出キット
AU6790300A (en) 1999-08-18 2001-03-13 Children's Medical Center Corporation Methods, compositions and kits for promoting recovery from damage to the central nervous system
US7537938B2 (en) * 2000-04-28 2009-05-26 Monogram Biosciences, Inc. Biomarker detection in circulating cells
JP2004523232A (ja) * 2001-01-23 2004-08-05 プリマゲン ホールディング ベー.フェー. 治療評価の手段と方法
AU2002306561A2 (en) * 2001-02-16 2003-09-02 Immunivest Corporation Methods and reagents for the rapid and efficient isolation of circulating cancer cells
CN1571634A (zh) * 2001-08-23 2005-01-26 免疫公司 用于分析的细胞和生物学标本的稳定
US7863012B2 (en) * 2004-02-17 2011-01-04 Veridex, Llc Analysis of circulating tumor cells, fragments, and debris
US6670142B2 (en) * 2001-10-26 2003-12-30 The Regents Of The University Of California Method for screening combinatorial bead library, capturing cells from body fluids, and ligands for cancer cells
CN100410275C (zh) * 2002-01-18 2008-08-13 皮埃尔法布雷医药公司 新的抗igf-ir抗体及其应用
US20040229294A1 (en) * 2002-05-21 2004-11-18 Po-Ying Chan-Hui ErbB surface receptor complexes as biomarkers
PL1656391T3 (pl) * 2003-08-13 2011-03-31 Pfizer Prod Inc Zmodyfikowane ludzkie przeciwciała IGF-1R
EP2322217A3 (en) * 2004-07-16 2011-09-28 Pfizer Products Inc. Combination treatment for non-hematologic malignancies using an anti-IGF-1R antibody
US20060045881A1 (en) * 2004-08-26 2006-03-02 Board Of Regents, The University Of Texas System Anti-cancer vaccines
WO2006041453A1 (en) 2004-09-30 2006-04-20 Immunivest Corporation Circulating tumor cells (ctc’s): apoptotic assessment in prostate cancer patients
EP1861509B1 (en) 2005-03-14 2015-09-09 Janssen Diagnostics, LLC A method for predicting progression free and overall survival at each follow-up time point during therapy of metastatic breast cancer patients using circulating tumor cells
US20070037173A1 (en) * 2005-08-12 2007-02-15 Allard Jeffrey W Circulating tumor cells (CTC's): early assessment of time to progression, survival and response to therapy in metastatic cancer patients
KR20090023423A (ko) 2006-06-02 2009-03-04 화이자 프로덕츠 인코포레이티드 순환 종양 세포 분석
JP2011501190A (ja) * 2007-10-24 2011-01-06 バイオマーカー ストラテジーズ リミテッド ライアビリティ カンパニー 細胞分析の進歩した方法および装置

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PT2027470E (pt) 2013-01-28
BRPI0712225A2 (pt) 2012-07-24
AU2007255110A1 (en) 2007-12-13
US20100028915A1 (en) 2010-02-04
JP2009539097A (ja) 2009-11-12
US20180011103A1 (en) 2018-01-11
AU2007255110A8 (en) 2014-04-10
US8940493B2 (en) 2015-01-27
RU2429486C2 (ru) 2011-09-20
CN101600966B (zh) 2014-07-02
EP2027470B1 (en) 2012-11-21
US20200191793A1 (en) 2020-06-18
MX2008015425A (es) 2008-12-12
WO2007141626A1 (en) 2007-12-13
AU2007255110B2 (en) 2014-03-20
ES2397971T3 (es) 2013-03-12
KR20130091788A (ko) 2013-08-19
BRPI0712225A8 (pt) 2019-01-22
AU2007255110B8 (en) 2014-04-10
CN101600966A (zh) 2009-12-09
CA2653745C (en) 2013-11-19
JP4943504B2 (ja) 2012-05-30
NZ573187A (en) 2011-11-25
IL195577A0 (en) 2009-09-01
SI2027470T1 (sl) 2013-01-31
ZA200810203B (en) 2020-05-27
CA2653745A1 (en) 2007-12-13
DK2027470T3 (da) 2013-02-04
KR20090023423A (ko) 2009-03-04
KR20140052081A (ko) 2014-05-02
IL195577A (en) 2012-12-31
PL2027470T3 (pl) 2013-03-29
EP2027470A1 (en) 2009-02-25
RU2008147415A (ru) 2010-06-10
KR101467136B1 (ko) 2014-12-01
US20150177252A1 (en) 2015-06-25
WO2007141626A8 (en) 2009-01-08

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PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20200527