HK1133018A1 - Anti-myostatin antibodies - Google Patents

Anti-myostatin antibodies

Info

Publication number
HK1133018A1
HK1133018A1 HK09111268.3A HK09111268A HK1133018A1 HK 1133018 A1 HK1133018 A1 HK 1133018A1 HK 09111268 A HK09111268 A HK 09111268A HK 1133018 A1 HK1133018 A1 HK 1133018A1
Authority
HK
Hong Kong
Prior art keywords
myostatin antibodies
myostatin
antibodies
Prior art date
Application number
HK09111268.3A
Other languages
English (en)
Inventor
Lihua Huang
Robert Owen Sayers
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of HK1133018A1 publication Critical patent/HK1133018A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/22—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/06—Anabolic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Neurology (AREA)
  • Endocrinology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
HK09111268.3A 2006-09-05 2009-12-02 Anti-myostatin antibodies HK1133018A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US82449806P 2006-09-05 2006-09-05
PCT/US2007/076604 WO2008030706A2 (en) 2006-09-05 2007-08-23 Anti-myostatin antibodies

Publications (1)

Publication Number Publication Date
HK1133018A1 true HK1133018A1 (en) 2010-03-12

Family

ID=39047560

Family Applications (1)

Application Number Title Priority Date Filing Date
HK09111268.3A HK1133018A1 (en) 2006-09-05 2009-12-02 Anti-myostatin antibodies

Country Status (22)

Country Link
US (1) US8063188B2 (de)
EP (1) EP2066695B1 (de)
JP (1) JP5058261B2 (de)
KR (1) KR101123531B1 (de)
CN (1) CN101511871B (de)
AU (1) AU2007292555B2 (de)
BR (1) BRPI0716249A2 (de)
CA (1) CA2661836A1 (de)
DK (1) DK2066695T3 (de)
EA (1) EA015916B1 (de)
ES (1) ES2404941T3 (de)
HK (1) HK1133018A1 (de)
HR (1) HRP20130320T1 (de)
IL (1) IL196806A0 (de)
MX (1) MX2009002470A (de)
NO (1) NO20091264L (de)
PL (1) PL2066695T3 (de)
PT (1) PT2066695E (de)
RS (1) RS52787B (de)
SI (1) SI2066695T1 (de)
UA (1) UA98308C2 (de)
WO (1) WO2008030706A2 (de)

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UA92504C2 (en) 2005-10-12 2010-11-10 Эли Лилли Энд Компани Anti-myostatin monoclonal antibody
US11046784B2 (en) 2006-03-31 2021-06-29 Chugai Seiyaku Kabushiki Kaisha Methods for controlling blood pharmacokinetics of antibodies
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AR074777A1 (es) 2008-12-19 2011-02-09 Glaxo Group Ltd Proteinas de union a antigeno
JO3340B1 (ar) 2010-05-26 2019-03-13 Regeneron Pharma مضادات حيوية لـعامل تمايز النمو 8 البشري
TW201210612A (en) 2010-06-03 2012-03-16 Glaxo Group Ltd Humanised antigen binding proteins
SG10201506405YA (en) 2010-08-16 2015-10-29 Amgen Inc Polypeptides That Bind Myostatin, Compositions And Methods
RU2658504C9 (ru) 2010-11-30 2018-08-21 Чугаи Сейяку Кабусики Кайся Антигенсвязывающая молекула, способная многократно связываться с множеством антигенных молекул
RS56796B1 (sr) 2011-11-14 2018-04-30 Regeneron Pharma Kompozicije i postupci za uvećanje mišićne mase i jačine mišića specifičnim antagonizovanjem gdf8 i/ili aktivina a
FR2982860B1 (fr) * 2011-11-18 2015-07-10 Ass Fr Contre Les Myopathies Utilisation de la fibromoduline et du lumican pour augmenter la masse musculaire
EP3597747B1 (de) 2012-08-24 2023-03-15 Chugai Seiyaku Kabushiki Kaisha Maus-fgcgammarii-spezifischer fc-antikörper
KR20210084688A (ko) 2012-08-24 2021-07-07 추가이 세이야쿠 가부시키가이샤 ＦｃγＲＩＩｂ 특이적 Ｆｃ영역 개변체
KR20220107082A (ko) 2012-09-13 2022-08-01 브리스톨-마이어스 스큅 컴퍼니 미오스타틴에 결합하는 피브로넥틴 기반 스캐폴드 도메인 단백질
WO2014163101A1 (ja) 2013-04-02 2014-10-09 中外製薬株式会社 Ｆｃ領域改変体
JP2016521283A (ja) 2013-05-06 2016-07-21 スカラー ロック インコーポレイテッドＳｃｈｏｌａｒ Ｒｏｃｋ，Ｉｎｃ． 成長因子モジュレーションのための組成物および方法
TW201920262A (zh) 2013-07-30 2019-06-01 美商再生元醫藥公司 抗活化素ａ之抗體及其用途
CN105992951A (zh) 2014-01-27 2016-10-05 诺华股份有限公司 预测肌萎缩的生物标志物、方法和用途
EP3215175A4 (de) * 2014-11-06 2018-06-27 Scholar Rock, Inc. Anti-pro/latentes-myostatin-antikörper und verwendungen davon
AU2015353767B2 (en) 2014-11-24 2021-09-09 Somalogic Operating Co., Inc. Nucleic acid compounds for binding growth differentiation factor 11
TWI808330B (zh) 2014-12-19 2023-07-11 日商中外製藥股份有限公司 抗肌抑素之抗體、含變異Fc區域之多胜肽及使用方法
WO2016120647A2 (en) 2015-01-30 2016-08-04 Debreceni Egyetem Muscle regeneration
SG10201907215QA (en) 2015-02-05 2019-09-27 Chugai Pharmaceutical Co Ltd Antibodies Comprising An Ion Concentration Dependent Antigen-Binding Domain, Fc Region Variants, Il-8-Binding Antibodies, And Uses Therof
TWI708845B (zh) * 2015-02-09 2020-11-01 美商身體邏輯股份有限公司 用於結合生長分化因數8之核酸化合物
CN107771081A (zh) 2015-04-15 2018-03-06 瑞泽恩制药公司 用gdf8抑制剂增加力量和功能的方法
HU230620B1 (hu) 2015-05-14 2017-04-28 ALU-ÖNTŐ Fémöntő és Fémmegmunkáló Ipari Eljárás vékonyfalú, tagolt, részletgazdag alumínium öntvények homokformázásos technológiával, gravitációs öntéssel történő előállítására
SG10201707267RA (en) * 2015-12-18 2017-10-30 Chugai Pharmaceutical Co Ltd Anti-myostatin antibodies, polypeptides containing variant fc regions, and methods of use
JP7141336B2 (ja) 2015-12-25 2022-09-22 中外製薬株式会社 抗ミオスタチン抗体および使用方法
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GB201620119D0 (en) * 2016-11-29 2017-01-11 Pharmafox Therapeutics Ag Compounds
PL3565592T3 (pl) * 2017-01-06 2023-08-21 Scholar Rock, Inc. Leczenie chorób metabolicznych poprzez inhibicję aktywacji miostatyny
CA3092334A1 (en) 2018-03-01 2019-09-06 Regeneron Pharmaceuticals, Inc. Methods for altering body composition
CN113195532A (zh) 2018-12-18 2021-07-30 瑞泽恩制药公司 使用针对瘦素受体、gdf8和活化素a的拮抗剂增加体重和瘦肌肉质量的组合物和方法
US20240199728A1 (en) 2022-09-21 2024-06-20 Regeneron Pharmaceuticals, Inc. Methods of treating obesity, diabetes, and liver dysfunction

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Also Published As

Publication number Publication date
EP2066695A2 (de) 2009-06-10
CN101511871A (zh) 2009-08-19
DK2066695T3 (da) 2013-06-10
CN101511871B (zh) 2012-07-18
WO2008030706A2 (en) 2008-03-13
PT2066695E (pt) 2013-05-23
US8063188B2 (en) 2011-11-22
MX2009002470A (es) 2009-03-20
RS52787B (en) 2013-10-31
UA98308C2 (en) 2012-05-10
ES2404941T3 (es) 2013-05-29
CA2661836A1 (en) 2008-03-13
US20100166764A1 (en) 2010-07-01
WO2008030706A3 (en) 2008-05-02
EP2066695B1 (de) 2013-03-27
AU2007292555A1 (en) 2008-03-13
NO20091264L (no) 2009-04-02
IL196806A0 (en) 2011-08-01
EA015916B1 (ru) 2011-12-30
KR101123531B1 (ko) 2012-04-20
AU2007292555B2 (en) 2012-05-31
JP2010502633A (ja) 2010-01-28
KR20090039821A (ko) 2009-04-22
JP5058261B2 (ja) 2012-10-24
PL2066695T3 (pl) 2013-08-30
HRP20130320T1 (en) 2013-05-31
EA200970251A1 (ru) 2009-08-28
BRPI0716249A2 (pt) 2013-09-03
SI2066695T1 (sl) 2013-05-31

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Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20170823