HK1133008A1 - Imidazole derivative - Google Patents
Imidazole derivativeInfo
- Publication number
- HK1133008A1 HK1133008A1 HK09111713.4A HK09111713A HK1133008A1 HK 1133008 A1 HK1133008 A1 HK 1133008A1 HK 09111713 A HK09111713 A HK 09111713A HK 1133008 A1 HK1133008 A1 HK 1133008A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- optionally substituted
- imidazole derivative
- represents optionally
- integer
- pharmaceutically acceptable
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
- C07D233/58—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring nitrogen atoms
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
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- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Immunology (AREA)
- Neurosurgery (AREA)
- Pulmonology (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Rheumatology (AREA)
- Physical Education & Sports Medicine (AREA)
- Pain & Pain Management (AREA)
- Dermatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Ophthalmology & Optometry (AREA)
- Hospice & Palliative Care (AREA)
- Urology & Nephrology (AREA)
- Child & Adolescent Psychology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Transplantation (AREA)
- Psychiatry (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Nutrition Science (AREA)
- Otolaryngology (AREA)
- Epidemiology (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2006239907 | 2006-09-05 | ||
PCT/JP2007/067261 WO2008029825A1 (fr) | 2006-09-05 | 2007-09-05 | Dérivé d'imidazole |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1133008A1 true HK1133008A1 (en) | 2010-03-12 |
Family
ID=39157251
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK09111713.4A HK1133008A1 (en) | 2006-09-05 | 2009-12-14 | Imidazole derivative |
Country Status (14)
Country | Link |
---|---|
US (2) | US8273738B2 (es) |
EP (1) | EP2090570B1 (es) |
JP (2) | JP4388997B2 (es) |
KR (1) | KR101404360B1 (es) |
CN (1) | CN101511796B (es) |
AT (1) | ATE532770T1 (es) |
AU (1) | AU2007292155B2 (es) |
CA (1) | CA2662112A1 (es) |
ES (1) | ES2376668T3 (es) |
HK (1) | HK1133008A1 (es) |
PL (1) | PL2090570T3 (es) |
PT (1) | PT2090570E (es) |
TW (1) | TWI386405B (es) |
WO (1) | WO2008029825A1 (es) |
Families Citing this family (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2732950C (en) | 2008-08-05 | 2013-10-01 | Daiichi Sankyo Company, Limited | Imidazopyridin-2-one derivatives |
PL2374802T3 (pl) | 2008-11-10 | 2014-09-30 | Kyowa Hakko Kirin Co Ltd | Inhibitor wytwarzania kinureniny |
EP2542089B1 (en) | 2010-03-05 | 2017-01-18 | Karyopharm Therapeutics, Inc. | Nuclear transport modulators and uses thereof |
WO2012099807A1 (en) | 2011-01-17 | 2012-07-26 | Karyopharm Therapeutics, Inc. | Olefin containing nuclear transport modulators and uses thereof |
UA115532C2 (uk) | 2011-07-29 | 2017-11-27 | Каріофарм Терапеутікс, Інк. | Модулятори нуклеарного транспорту, що містять гідразид, і їхнє застосування |
JP6006794B2 (ja) * | 2011-07-29 | 2016-10-12 | カリオファーム セラピューティクス,インコーポレイテッド | 核内輸送調節因子およびその使用 |
EA027451B1 (ru) * | 2011-08-30 | 2017-07-31 | Схди Фаундейшн, Инк. | Ингибиторы кинуренин-3-монооксигеназы, фармацевтические композиции и их применение |
MX346147B (es) | 2012-03-07 | 2017-03-09 | Inst Of Cancer Research: Royal Cancer Hospital (The) | Compuestos de 3-aril-5-substituido-isoquinolin-1-ona y su uso terapeutico. |
DK2858991T3 (en) | 2012-05-09 | 2018-11-26 | Biogen Ma Inc | CELL NUCLEAR TRANSPORT MODULATORS AND APPLICATIONS THEREOF |
EP2951174B1 (en) | 2013-01-30 | 2017-04-26 | Bayer Pharma Aktiengesellschaft | Amino-substituted isothiazoles |
US9133166B2 (en) | 2013-03-14 | 2015-09-15 | Quanticel Pharmaceuticals, Inc. | Histone demethylase inhibitors |
US10202366B2 (en) | 2013-03-15 | 2019-02-12 | Karyopharm Therapeutics Inc. | Methods of promoting wound healing using CRM1 inhibitors |
CN105492433B (zh) * | 2013-03-29 | 2018-11-23 | 武田药品工业株式会社 | 6-(5-羟基-1h-吡唑-1-基)烟碱酰胺衍生物和其作为phd抑制剂的用途 |
WO2014205389A1 (en) | 2013-06-21 | 2014-12-24 | Karyopharm Therapeutics Inc. | Nuclear transport modulators and uses thereof |
CN103450089B (zh) * | 2013-09-03 | 2015-07-15 | 张家港市信谊化工有限公司 | 一种4-苯基咪唑的制备方法 |
NO3044221T3 (es) | 2013-09-11 | 2018-07-21 | ||
WO2015163446A1 (ja) * | 2014-04-25 | 2015-10-29 | 協和発酵キリン株式会社 | イミダゾール化合物の製造方法 |
US10258621B2 (en) | 2014-07-17 | 2019-04-16 | Chdi Foundation, Inc. | Methods and compositions for treating HIV-related disorders |
DK3180331T3 (da) | 2014-08-15 | 2022-09-12 | Karyopharm Therapeutics Inc | Polymorfer af selinexor |
US10112939B2 (en) | 2014-08-21 | 2018-10-30 | Bristol-Myers Squibb Company | Tied-back benzamide derivatives as potent rock inhibitors |
WO2017117529A1 (en) | 2015-12-31 | 2017-07-06 | Karyopharm Therapeutics Inc. | Nuclear transport modulators and uses thereof |
MA43530A (fr) | 2015-12-31 | 2018-11-07 | Karyopharm Therapeutics Inc | Modulateurs de transport nucléaire et leurs utilisations |
GB201614934D0 (en) * | 2016-09-02 | 2016-10-19 | Glaxosmithkline Intellectual Property (No 2) Ltd | Chemical compounds |
WO2018098472A1 (en) | 2016-11-28 | 2018-05-31 | Karyopharm Therapeutics Inc. | Crm1 inhibitors for treating epilepsy |
WO2018166855A1 (en) | 2017-03-16 | 2018-09-20 | Basf Se | Heterobicyclic substituted dihydroisoxazoles |
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US2008A (en) * | 1841-03-18 | Gas-lamp eok conducting gas pkom ah elevated buhner to one below it | ||
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-
2007
- 2007-09-05 TW TW096133025A patent/TWI386405B/zh not_active IP Right Cessation
- 2007-09-05 US US12/440,237 patent/US8273738B2/en active Active
- 2007-09-05 CN CN2007800329106A patent/CN101511796B/zh not_active Expired - Fee Related
- 2007-09-05 PL PL07828189T patent/PL2090570T3/pl unknown
- 2007-09-05 PT PT07828189T patent/PT2090570E/pt unknown
- 2007-09-05 AU AU2007292155A patent/AU2007292155B2/en not_active Ceased
- 2007-09-05 ES ES07828189T patent/ES2376668T3/es active Active
- 2007-09-05 AT AT07828189T patent/ATE532770T1/de active
- 2007-09-05 CA CA002662112A patent/CA2662112A1/en not_active Abandoned
- 2007-09-05 EP EP07828189A patent/EP2090570B1/en active Active
- 2007-09-05 JP JP2008533175A patent/JP4388997B2/ja not_active Expired - Fee Related
- 2007-09-05 WO PCT/JP2007/067261 patent/WO2008029825A1/ja active Application Filing
- 2007-09-05 KR KR1020097006879A patent/KR101404360B1/ko active IP Right Grant
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2009
- 2009-06-15 JP JP2009141916A patent/JP5221453B2/ja not_active Expired - Fee Related
- 2009-12-14 HK HK09111713.4A patent/HK1133008A1/xx not_active IP Right Cessation
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2012
- 2012-07-25 US US13/558,325 patent/US20120289502A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
CN101511796B (zh) | 2012-05-09 |
CA2662112A1 (en) | 2008-03-13 |
JP2009203238A (ja) | 2009-09-10 |
KR20090051775A (ko) | 2009-05-22 |
TWI386405B (zh) | 2013-02-21 |
JP5221453B2 (ja) | 2013-06-26 |
PT2090570E (pt) | 2011-12-29 |
KR101404360B1 (ko) | 2014-06-09 |
CN101511796A (zh) | 2009-08-19 |
JP4388997B2 (ja) | 2009-12-24 |
JPWO2008029825A1 (ja) | 2010-01-21 |
ES2376668T3 (es) | 2012-03-15 |
EP2090570A1 (en) | 2009-08-19 |
US20100152178A1 (en) | 2010-06-17 |
EP2090570B1 (en) | 2011-11-09 |
AU2007292155A1 (en) | 2008-03-13 |
PL2090570T3 (pl) | 2012-03-30 |
TW200819443A (en) | 2008-05-01 |
AU2007292155B2 (en) | 2012-11-01 |
EP2090570A4 (en) | 2010-09-01 |
WO2008029825A1 (fr) | 2008-03-13 |
US20120289502A1 (en) | 2012-11-15 |
ATE532770T1 (de) | 2011-11-15 |
US8273738B2 (en) | 2012-09-25 |
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