HK1129689A1 - 標靶補體因子 來治療疾病 - Google Patents
標靶補體因子 來治療疾病Info
- Publication number
- HK1129689A1 HK1129689A1 HK09108674.7A HK09108674A HK1129689A1 HK 1129689 A1 HK1129689 A1 HK 1129689A1 HK 09108674 A HK09108674 A HK 09108674A HK 1129689 A1 HK1129689 A1 HK 1129689A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- diseases
- treatment
- complement factor
- targeting complement
- targeting
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/04—Antipruritics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/04—Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70596—Molecules with a "CD"-designation not provided for elsewhere
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Immunology (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Cell Biology (AREA)
- Urology & Nephrology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Rheumatology (AREA)
- Pulmonology (AREA)
- Pain & Pain Management (AREA)
- Heart & Thoracic Surgery (AREA)
- Dermatology (AREA)
- Neurology (AREA)
- Ophthalmology & Optometry (AREA)
- Transplantation (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US81574806P | 2006-06-21 | 2006-06-21 | |
PCT/US2007/014602 WO2007149567A2 (en) | 2006-06-21 | 2007-06-21 | Targeting complement factor h for treatment of diseases |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1129689A1 true HK1129689A1 (zh) | 2009-12-04 |
Family
ID=38695591
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK09108674.7A HK1129689A1 (zh) | 2006-06-21 | 2009-09-23 | 標靶補體因子 來治療疾病 |
HK15106966.0A HK1206368A1 (zh) | 2006-06-21 | 2015-07-21 | 分子治療疾病的靶向補體因子 |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK15106966.0A HK1206368A1 (zh) | 2006-06-21 | 2015-07-21 | 分子治療疾病的靶向補體因子 |
Country Status (14)
Country | Link |
---|---|
US (3) | US7759304B2 (zh) |
EP (2) | EP2044111B1 (zh) |
JP (1) | JP5250548B2 (zh) |
CN (1) | CN101563363B (zh) |
AU (1) | AU2007261315B2 (zh) |
BR (1) | BRPI0712987A2 (zh) |
CA (1) | CA2656063C (zh) |
DK (1) | DK2044111T3 (zh) |
ES (1) | ES2523640T3 (zh) |
HK (2) | HK1129689A1 (zh) |
PL (1) | PL2044111T3 (zh) |
PT (1) | PT2044111E (zh) |
SI (1) | SI2044111T1 (zh) |
WO (1) | WO2007149567A2 (zh) |
Families Citing this family (45)
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US6820011B2 (en) * | 2001-04-11 | 2004-11-16 | The Regents Of The University Of Colorado | Three-dimensional structure of complement receptor type 2 and uses thereof |
JP4915980B2 (ja) * | 2002-11-15 | 2012-04-11 | エムユーエスシー ファウンデーション フォー リサーチ デベロップメント | 補体レセプター2標的化補体調節因子 |
ES2432112T3 (es) * | 2004-02-10 | 2013-11-29 | The Regents Of The University Of Colorado, A Body Corporate | Inhibición del factor B, de la vía alternativa del complemento y métodos relacionados |
US8911733B2 (en) * | 2005-05-26 | 2014-12-16 | Musc Foundation For Research Development | Inhibition of the alternative complement pathway for treatment of traumatic brain injury, spinal cord injury and related conditions |
PT2044111E (pt) | 2006-06-21 | 2014-11-12 | Univ Colorado Regents | Abordagem seletiva do fator h do complemento para o tratamento de doenças |
US8664176B2 (en) | 2006-10-20 | 2014-03-04 | Celldex Therapeutics, Inc. | Treatment for age-related macular degeneration and other diseases of the eye |
EP2236518B1 (en) | 2007-03-14 | 2014-08-06 | Alexion Cambridge Corporation | Humaneered anti-factor B antibody |
CA2687395C (en) * | 2007-05-03 | 2017-07-11 | Medizinische Universitat Innsbruck | Complement factor h-derived short consensus repeat-antibody constructs |
US20090324585A1 (en) * | 2008-06-12 | 2009-12-31 | The Trustees of the Leland Standford Junior University | Complement inhibitory agents as therapeutics in posttraumatic and degenerative arthritis |
GB0904427D0 (en) * | 2009-03-13 | 2009-04-29 | Lachmann Peter | Treatment of diseases related to hyperactivity of the complement system |
AU2010266127B2 (en) * | 2009-07-02 | 2015-11-05 | Musc Foundation For Research Development | Methods of stimulating liver regeneration |
KR20120130748A (ko) | 2009-11-05 | 2012-12-03 | 알렉시온 캠브리지 코포레이션 | 발작성 야간 혈색소뇨증, 용혈성 빈혈, 및 혈관내 및 혈관외 용혈을 수반한 질환 상태의 치료 |
GB0922659D0 (en) * | 2009-12-24 | 2010-02-10 | Univ Edinburgh | Factor H |
CA2791841C (en) * | 2010-03-05 | 2023-01-03 | Rigshospitalet | Chimeric inhibitor molecules of complement activation |
EP2569332B1 (en) * | 2010-05-14 | 2019-01-09 | The Regents of the University of Colorado, A Body Corporate | Improved complement receptor 2 (cr2) targeting groups |
CA2803588A1 (en) * | 2010-06-22 | 2011-12-29 | The Regents Of The University Of Colorado, A Body Corporate | Antibodies to the c3d fragment of complement component 3 |
EP2785744B1 (en) | 2011-12-01 | 2017-10-04 | AP Biosciences, Inc. | Protein inhibitors to complement and vegf pathways and methods of use thereof |
FR2988298A1 (fr) * | 2012-03-23 | 2013-09-27 | Lfb Biotechnologies | Facteur h pour son utilisation comme molecule antioxydante |
EP2855529A4 (en) | 2012-05-24 | 2015-12-09 | Alexion Pharma Inc | HUMANIZED ANTI-FACTOR B ANTIBODIES |
AU2013302441B2 (en) | 2012-08-17 | 2018-05-10 | The Regents Of The University Of Colorado, A Body Corporate | Compositions and methods for detecting complement activation |
US10413620B2 (en) | 2012-08-17 | 2019-09-17 | The Regents Of The University Of Colorado, A Body Corporate | Light-emitting versions of the monoclonal antibody to C3D (MAB 3D29) for imaging |
CA2906527A1 (en) | 2013-03-14 | 2014-09-25 | Baxalta Incorporated | Factor h for transplantation |
AU2014236782B2 (en) * | 2013-03-14 | 2019-01-03 | Baxalta GmbH | Factor H for treatment of rheumatoid arthritis |
AU2013202965B2 (en) | 2013-03-15 | 2016-07-21 | Takeda Pharmaceutical Company Limited | Improved method for producing factor h from a plasma precipitation fraction |
CN104293901A (zh) * | 2013-07-19 | 2015-01-21 | 金弗康生物科技(上海)有限公司 | 一种用于系统性红斑狼疮的早期诊断的检测试剂盒 |
CN105683759B (zh) | 2013-08-07 | 2019-03-29 | 瑞颂医药公司 | 非典型溶血性尿毒综合征(aHUS)生物标志物蛋白 |
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CN104231085B (zh) * | 2013-09-05 | 2017-03-15 | 复旦大学附属肿瘤医院 | 靶向特异性补体系统抑制剂、其制备方法及应用 |
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FR3046355A1 (fr) * | 2015-12-30 | 2017-07-07 | Lab Francais Du Fractionnement | Fragments du facteur h pour son utilisation comme agent anti-angiogenique |
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- 2007-06-21 EP EP14170690.3A patent/EP2826788B1/en active Active
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WO2007149567A2 (en) | 2007-12-27 |
AU2007261315A1 (en) | 2007-12-27 |
US8569225B2 (en) | 2013-10-29 |
PT2044111E (pt) | 2014-11-12 |
CA2656063A1 (en) | 2007-12-27 |
HK1206368A1 (zh) | 2016-01-08 |
US20140073572A1 (en) | 2014-03-13 |
CN101563363B (zh) | 2013-01-02 |
EP2826788A1 (en) | 2015-01-21 |
EP2826788B1 (en) | 2017-12-13 |
US7759304B2 (en) | 2010-07-20 |
DK2044111T3 (en) | 2014-11-17 |
US9212212B2 (en) | 2015-12-15 |
JP5250548B2 (ja) | 2013-07-31 |
BRPI0712987A2 (pt) | 2012-04-10 |
ES2523640T3 (es) | 2014-11-28 |
SI2044111T1 (sl) | 2015-02-27 |
JP2009540831A (ja) | 2009-11-26 |
EP2044111A2 (en) | 2009-04-08 |
US20080221011A1 (en) | 2008-09-11 |
CA2656063C (en) | 2016-10-18 |
US20110015127A1 (en) | 2011-01-20 |
CN101563363A (zh) | 2009-10-21 |
AU2007261315B2 (en) | 2012-10-25 |
WO2007149567A3 (en) | 2008-05-02 |
PL2044111T3 (pl) | 2015-02-27 |
EP2044111B1 (en) | 2014-08-13 |
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