HK1121468A1 - Synthetic mecp2 sequence for protein substitution therapy - Google Patents

Synthetic mecp2 sequence for protein substitution therapy

Info

Publication number
HK1121468A1
HK1121468A1 HK09101479.9A HK09101479A HK1121468A1 HK 1121468 A1 HK1121468 A1 HK 1121468A1 HK 09101479 A HK09101479 A HK 09101479A HK 1121468 A1 HK1121468 A1 HK 1121468A1
Authority
HK
Hong Kong
Prior art keywords
protein
proteins
nucleic acid
relates
substitution therapy
Prior art date
Application number
HK09101479.9A
Other languages
English (en)
Inventor
Franco Antonio Laccone
Original Assignee
Univ Goettingen Georg August
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Goettingen Georg August filed Critical Univ Goettingen Georg August
Publication of HK1121468A1 publication Critical patent/HK1121468A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702—Regulators; Modulating activity
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
HK09101479.9A 2006-04-07 2009-02-17 Synthetic mecp2 sequence for protein substitution therapy HK1121468A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/EP2006/003203 WO2007115578A1 (en) 2006-04-07 2006-04-07 Synthetic mecp2 sequence for protein substitution therapy

Publications (1)

Publication Number Publication Date
HK1121468A1 true HK1121468A1 (en) 2009-04-24

Family

ID=36589309

Family Applications (1)

Application Number Title Priority Date Filing Date
HK09101479.9A HK1121468A1 (en) 2006-04-07 2009-02-17 Synthetic mecp2 sequence for protein substitution therapy

Country Status (16)

Country Link
US (1) US8226930B2 (hr)
EP (1) EP2010563B1 (hr)
JP (1) JP5102283B2 (hr)
CN (1) CN101415726B (hr)
AT (1) ATE500265T1 (hr)
AU (1) AU2006341726B2 (hr)
CA (1) CA2647125C (hr)
DE (1) DE602006020501D1 (hr)
DK (1) DK2010563T3 (hr)
ES (1) ES2362195T3 (hr)
HK (1) HK1121468A1 (hr)
HR (1) HRP20110386T1 (hr)
IL (1) IL194274A (hr)
PL (1) PL2010563T3 (hr)
SI (1) SI2010563T1 (hr)
WO (1) WO2007115578A1 (hr)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1398191B1 (it) * 2010-02-17 2013-02-14 Ist Superiore Sanita Uso di tossine che attivano le rho gtpasi per il trattamento e/o la prevenzione della sintomatologia associata alla sindrome di rett (rtt).
US9920317B2 (en) 2010-11-12 2018-03-20 The General Hospital Corporation Polycomb-associated non-coding RNAs
EP3702460A1 (en) 2010-11-12 2020-09-02 The General Hospital Corporation Polycomb-associated non-coding rnas
CN104583401A (zh) 2012-05-16 2015-04-29 Rana医疗有限公司 用于调节atp2a2表达的组合物和方法
US20150152410A1 (en) * 2012-05-16 2015-06-04 Rana Therapeutics, Inc. Compositions and methods for modulating mecp2 expression
WO2013173645A1 (en) 2012-05-16 2013-11-21 Rana Therapeutics, Inc. Compositions and methods for modulating utrn expression
KR20150030205A (ko) 2012-05-16 2015-03-19 라나 테라퓨틱스, 인크. Smn 유전자 패밀리 발현을 조절하기 위한 조성물 및 방법
CA2873769A1 (en) 2012-05-16 2013-11-21 Rana Therapeutics Inc. Compositions and methods for modulating hemoglobin gene family expression
US10837014B2 (en) 2012-05-16 2020-11-17 Translate Bio Ma, Inc. Compositions and methods for modulating SMN gene family expression
WO2014130408A1 (en) * 2013-02-20 2014-08-28 The Research Foundation For The State University Of New York Regulators of rab5 activity
US10858650B2 (en) 2014-10-30 2020-12-08 The General Hospital Corporation Methods for modulating ATRX-dependent gene repression
EP3271460A4 (en) 2015-03-17 2019-03-13 The General Hospital Corporation INTERACTOME RNA OF COMPLEX REPRESSIVE POLYCOMB 1 (PRC1)
TWI601821B (zh) * 2016-04-15 2017-10-11 中央研究院 治療神經發展性疾病
CA3057425A1 (en) * 2017-03-24 2018-09-27 The University Court Of The University Of Edinburgh Mecp2 based therapy
WO2019079462A1 (en) * 2017-10-17 2019-04-25 President And Fellows Of Harvard College TRANSCRIPTION MODULATION SYSTEMS BASED ON CAS9
KR102052097B1 (ko) * 2017-11-30 2019-12-05 한국과학기술연구원 Mecp2 단백질 또는 이를 암호화하는 폴리뉴클레오티드를 포함하는 퇴행성 뇌질환 예방 또는 치료용 조성물
EP3973060A4 (en) * 2019-04-24 2023-05-10 The Trustees of The University of Pennsylvania COMPOSITIONS USEFUL FOR THE TREATMENT OF RETT SYNDROME
WO2023235648A1 (en) * 2022-06-03 2023-12-07 The Regents Of The University Of California Nuclear Delivery and Transcriptional Repression with a Cell-penetrant MeCP2

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000062067A1 (en) 1999-02-28 2000-10-19 Washington University Novel transduction molecules and methods for using same
US6709817B1 (en) 1999-09-07 2004-03-23 Baylor College Of Medicine Method of screening Rett syndrome by detecting a mutation in MECP2
US20040126877A1 (en) * 2001-04-20 2004-07-01 Man-Wook Hur Repressors for hiv transcription and methods thereof
CA2554380C (en) * 2004-02-17 2015-05-19 The Hospital For Sick Children Mecp2e1 gene

Also Published As

Publication number Publication date
US20090233856A1 (en) 2009-09-17
AU2006341726B2 (en) 2012-09-20
CA2647125C (en) 2015-02-03
SI2010563T1 (sl) 2011-07-29
JP2009532045A (ja) 2009-09-10
WO2007115578A8 (en) 2008-10-30
CN101415726B (zh) 2013-07-31
ES2362195T3 (es) 2011-06-29
PL2010563T3 (pl) 2011-11-30
WO2007115578A1 (en) 2007-10-18
ATE500265T1 (de) 2011-03-15
DE602006020501D1 (de) 2011-04-14
JP5102283B2 (ja) 2012-12-19
IL194274A (en) 2011-07-31
DK2010563T3 (da) 2011-05-23
EP2010563A1 (en) 2009-01-07
US8226930B2 (en) 2012-07-24
CA2647125A1 (en) 2007-10-18
CN101415726A (zh) 2009-04-22
HRP20110386T1 (hr) 2011-08-31
AU2006341726A1 (en) 2007-10-18
EP2010563B1 (en) 2011-03-02

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Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20180407