DK2010563T3 - Syntetisk MeCP2 sekvens til proteinsubstitutionsterapi - Google Patents
Syntetisk MeCP2 sekvens til proteinsubstitutionsterapiInfo
- Publication number
- DK2010563T3 DK2010563T3 DK06724141.4T DK06724141T DK2010563T3 DK 2010563 T3 DK2010563 T3 DK 2010563T3 DK 06724141 T DK06724141 T DK 06724141T DK 2010563 T3 DK2010563 T3 DK 2010563T3
- Authority
- DK
- Denmark
- Prior art keywords
- protein
- proteins
- nucleic acid
- relates
- substitution therapy
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4702—Regulators; Modulating activity
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/EP2006/003203 WO2007115578A1 (en) | 2006-04-07 | 2006-04-07 | Synthetic mecp2 sequence for protein substitution therapy |
Publications (1)
Publication Number | Publication Date |
---|---|
DK2010563T3 true DK2010563T3 (da) | 2011-05-23 |
Family
ID=36589309
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK06724141.4T DK2010563T3 (da) | 2006-04-07 | 2006-04-07 | Syntetisk MeCP2 sekvens til proteinsubstitutionsterapi |
Country Status (16)
Country | Link |
---|---|
US (1) | US8226930B2 (da) |
EP (1) | EP2010563B1 (da) |
JP (1) | JP5102283B2 (da) |
CN (1) | CN101415726B (da) |
AT (1) | ATE500265T1 (da) |
AU (1) | AU2006341726B2 (da) |
CA (1) | CA2647125C (da) |
DE (1) | DE602006020501D1 (da) |
DK (1) | DK2010563T3 (da) |
ES (1) | ES2362195T3 (da) |
HK (1) | HK1121468A1 (da) |
HR (1) | HRP20110386T1 (da) |
IL (1) | IL194274A (da) |
PL (1) | PL2010563T3 (da) |
SI (1) | SI2010563T1 (da) |
WO (1) | WO2007115578A1 (da) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IT1398191B1 (it) * | 2010-02-17 | 2013-02-14 | Ist Superiore Sanita | Uso di tossine che attivano le rho gtpasi per il trattamento e/o la prevenzione della sintomatologia associata alla sindrome di rett (rtt). |
JP6336755B2 (ja) | 2010-11-12 | 2018-06-06 | ザ ジェネラル ホスピタル コーポレイション | ポリコームに関連する非コードrna |
US9920317B2 (en) | 2010-11-12 | 2018-03-20 | The General Hospital Corporation | Polycomb-associated non-coding RNAs |
WO2013173608A1 (en) | 2012-05-16 | 2013-11-21 | Rana Therapeutics, Inc. | Compositions and methods for modulating mecp2 expression |
US10174323B2 (en) | 2012-05-16 | 2019-01-08 | The General Hospital Corporation | Compositions and methods for modulating ATP2A2 expression |
JP2015523854A (ja) | 2012-05-16 | 2015-08-20 | ラナ セラピューティクス インコーポレイテッド | Smn遺伝子ファミリー発現を調節するための組成物及び方法 |
AU2013262656A1 (en) | 2012-05-16 | 2015-01-22 | Rana Therapeutics, Inc. | Compositions and methods for modulating UTRN expression |
AP2014008100A0 (en) | 2012-05-16 | 2014-12-31 | Gen Hospital Corp | Compositions and methods for modulating hemoglobingene family expression |
US10837014B2 (en) | 2012-05-16 | 2020-11-17 | Translate Bio Ma, Inc. | Compositions and methods for modulating SMN gene family expression |
WO2014130408A1 (en) * | 2013-02-20 | 2014-08-28 | The Research Foundation For The State University Of New York | Regulators of rab5 activity |
CA2966044A1 (en) | 2014-10-30 | 2016-05-06 | The General Hospital Corporation | Methods for modulating atrx-dependent gene repression |
WO2016149455A2 (en) | 2015-03-17 | 2016-09-22 | The General Hospital Corporation | The rna interactome of polycomb repressive complex 1 (prc1) |
TWI601821B (zh) * | 2016-04-15 | 2017-10-11 | 中央研究院 | 治療神經發展性疾病 |
US11969479B2 (en) * | 2017-03-24 | 2024-04-30 | The University Court Of The University Of Edinburgh | MeCP2 expression cassettes |
US11629342B2 (en) | 2017-10-17 | 2023-04-18 | President And Fellows Of Harvard College | Cas9-based transcription modulation systems |
KR102052097B1 (ko) * | 2017-11-30 | 2019-12-05 | 한국과학기술연구원 | Mecp2 단백질 또는 이를 암호화하는 폴리뉴클레오티드를 포함하는 퇴행성 뇌질환 예방 또는 치료용 조성물 |
JP2022530095A (ja) * | 2019-04-24 | 2022-06-27 | ザ・トラステイーズ・オブ・ザ・ユニバーシテイ・オブ・ペンシルベニア | レット症候群の治療に有用な組成物 |
WO2023235648A1 (en) * | 2022-06-03 | 2023-12-07 | The Regents Of The University Of California | Nuclear Delivery and Transcriptional Repression with a Cell-penetrant MeCP2 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1157275A4 (en) | 1999-02-28 | 2003-01-15 | Univ Washington | NEW TRANSDUCTION MOLECULES AND METHOD FOR USING THE SAME |
US6709817B1 (en) | 1999-09-07 | 2004-03-23 | Baylor College Of Medicine | Method of screening Rett syndrome by detecting a mutation in MECP2 |
US20040126877A1 (en) * | 2001-04-20 | 2004-07-01 | Man-Wook Hur | Repressors for hiv transcription and methods thereof |
JP5830213B2 (ja) * | 2004-02-17 | 2015-12-09 | ザ ホスピタル フォー シック チルドレン | Mecp2e1遺伝子 |
-
2006
- 2006-04-07 DK DK06724141.4T patent/DK2010563T3/da active
- 2006-04-07 PL PL06724141T patent/PL2010563T3/pl unknown
- 2006-04-07 CN CN2006800541487A patent/CN101415726B/zh not_active Expired - Fee Related
- 2006-04-07 EP EP06724141A patent/EP2010563B1/en active Active
- 2006-04-07 WO PCT/EP2006/003203 patent/WO2007115578A1/en active Application Filing
- 2006-04-07 ES ES06724141T patent/ES2362195T3/es active Active
- 2006-04-07 DE DE602006020501T patent/DE602006020501D1/de active Active
- 2006-04-07 SI SI200631023T patent/SI2010563T1/sl unknown
- 2006-04-07 AT AT06724141T patent/ATE500265T1/de active
- 2006-04-07 CA CA2647125A patent/CA2647125C/en not_active Expired - Fee Related
- 2006-04-07 JP JP2009503417A patent/JP5102283B2/ja not_active Expired - Fee Related
- 2006-04-07 AU AU2006341726A patent/AU2006341726B2/en not_active Ceased
- 2006-04-07 US US12/295,856 patent/US8226930B2/en active Active
-
2008
- 2008-09-22 IL IL194274A patent/IL194274A/en not_active IP Right Cessation
-
2009
- 2009-02-17 HK HK09101479.9A patent/HK1121468A1/xx not_active IP Right Cessation
-
2011
- 2011-05-24 HR HR20110386T patent/HRP20110386T1/hr unknown
Also Published As
Publication number | Publication date |
---|---|
AU2006341726B2 (en) | 2012-09-20 |
DE602006020501D1 (de) | 2011-04-14 |
WO2007115578A8 (en) | 2008-10-30 |
EP2010563B1 (en) | 2011-03-02 |
CN101415726B (zh) | 2013-07-31 |
JP5102283B2 (ja) | 2012-12-19 |
IL194274A (en) | 2011-07-31 |
CA2647125A1 (en) | 2007-10-18 |
CA2647125C (en) | 2015-02-03 |
HK1121468A1 (en) | 2009-04-24 |
US8226930B2 (en) | 2012-07-24 |
HRP20110386T1 (hr) | 2011-08-31 |
SI2010563T1 (sl) | 2011-07-29 |
US20090233856A1 (en) | 2009-09-17 |
ATE500265T1 (de) | 2011-03-15 |
WO2007115578A1 (en) | 2007-10-18 |
JP2009532045A (ja) | 2009-09-10 |
ES2362195T3 (es) | 2011-06-29 |
EP2010563A1 (en) | 2009-01-07 |
AU2006341726A1 (en) | 2007-10-18 |
CN101415726A (zh) | 2009-04-22 |
PL2010563T3 (pl) | 2011-11-30 |
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