IT1398191B1 - Uso di tossine che attivano le rho gtpasi per il trattamento e/o la prevenzione della sintomatologia associata alla sindrome di rett (rtt). - Google Patents

Uso di tossine che attivano le rho gtpasi per il trattamento e/o la prevenzione della sintomatologia associata alla sindrome di rett (rtt).

Info

Publication number
IT1398191B1
IT1398191B1 ITRM2010A000063A ITRM20100063A IT1398191B1 IT 1398191 B1 IT1398191 B1 IT 1398191B1 IT RM2010A000063 A ITRM2010A000063 A IT RM2010A000063A IT RM20100063 A ITRM20100063 A IT RM20100063A IT 1398191 B1 IT1398191 B1 IT 1398191B1
Authority
IT
Italy
Prior art keywords
gtpasis
rtt
toxins
prevention
treatment
Prior art date
Application number
ITRM2010A000063A
Other languages
English (en)
Inventor
Alessia Fabbri
Filippis Bianca De
Carla Fiorentini
Giovanni Laviola
Laura Ricceri
Original Assignee
Ist Superiore Sanita
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ist Superiore Sanita filed Critical Ist Superiore Sanita
Priority to ITRM2010A000063A priority Critical patent/IT1398191B1/it
Priority to EP11713878.4A priority patent/EP2536424B1/en
Priority to PCT/IT2011/000039 priority patent/WO2011101881A2/en
Publication of ITRM20100063A1 publication Critical patent/ITRM20100063A1/it
Application granted granted Critical
Publication of IT1398191B1 publication Critical patent/IT1398191B1/it

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/164—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Plant Substances (AREA)
ITRM2010A000063A 2010-02-17 2010-02-17 Uso di tossine che attivano le rho gtpasi per il trattamento e/o la prevenzione della sintomatologia associata alla sindrome di rett (rtt). IT1398191B1 (it)

Priority Applications (3)

Application Number Priority Date Filing Date Title
ITRM2010A000063A IT1398191B1 (it) 2010-02-17 2010-02-17 Uso di tossine che attivano le rho gtpasi per il trattamento e/o la prevenzione della sintomatologia associata alla sindrome di rett (rtt).
EP11713878.4A EP2536424B1 (en) 2010-02-17 2011-02-15 Use of rho gtpase activating toxins for the treatment and/or prevention of symptomatology associated with rett syndrome
PCT/IT2011/000039 WO2011101881A2 (en) 2010-02-17 2011-02-15 Use of rho gtpase activating toxines for the treatment and/or prevention of symptomatology associated with rett syndrome

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITRM2010A000063A IT1398191B1 (it) 2010-02-17 2010-02-17 Uso di tossine che attivano le rho gtpasi per il trattamento e/o la prevenzione della sintomatologia associata alla sindrome di rett (rtt).

Publications (2)

Publication Number Publication Date
ITRM20100063A1 ITRM20100063A1 (it) 2011-08-18
IT1398191B1 true IT1398191B1 (it) 2013-02-14

Family

ID=42664670

Family Applications (1)

Application Number Title Priority Date Filing Date
ITRM2010A000063A IT1398191B1 (it) 2010-02-17 2010-02-17 Uso di tossine che attivano le rho gtpasi per il trattamento e/o la prevenzione della sintomatologia associata alla sindrome di rett (rtt).

Country Status (3)

Country Link
EP (1) EP2536424B1 (it)
IT (1) IT1398191B1 (it)
WO (1) WO2011101881A2 (it)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2017195224A1 (en) 2016-05-09 2017-11-16 Istituto Superiore Di Sanita' Rho gtpase activating bacterial toxins for use in the treatment of disorders of the central nervous system by mucosal administration

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5830213B2 (ja) * 2004-02-17 2015-12-09 ザ ホスピタル フォー シック チルドレン Ｍｅｃｐ２ｅ１遺伝子
EP1570856A3 (en) * 2004-02-26 2005-10-12 Institut National De La Sante Et De La Recherche Medicale (Inserm) A vaccine composition comprising an immunoadjuvant compound consisting of a RHO GTPase family activator
JP2008050263A (ja) * 2004-11-11 2008-03-06 Univ Kurume Ｒｅｔｔ症候群を治療する医薬
GB0506797D0 (en) * 2005-04-04 2005-05-11 Istituto Superiore Di Sanito Treatment of cognitive and learning impairment
ITRM20050422A1 (it) * 2005-08-05 2007-02-06 Consiglio Nazionale Ricerche Fattori proteici dermonecrotizzanti di origine batterica e relativi usi in campo medico.
CA2647125C (en) * 2006-04-07 2015-02-03 Georg-August-Universitaet Goettingen Stiftung Oeffentlichen Rechts Synthetic mecp2 sequence for protein substitution therapy

Also Published As

Publication number Publication date
EP2536424A2 (en) 2012-12-26
WO2011101881A2 (en) 2011-08-25
EP2536424B1 (en) 2014-06-04
ITRM20100063A1 (it) 2011-08-18
WO2011101881A3 (en) 2011-10-27

Similar Documents

Publication Publication Date Title
BR112015001838A2 (pt) composições de inibidor de efluxo e métodos de tratamento utilizando o mesmo.
BR112012003792A2 (pt) gel tópico, e, uso do gel tópico.
BR112012002349A2 (pt) composto,e, uso do mesmo
BR112012004335A2 (pt) composto, composição farmacêutica, e, uso do composto.
IT1399435B1 (it) Anta per mobili con pannello amovibile - intercambiabile.
SMT201400008B (it) Uso di betanecolo per il trattamento di xerostomia
BRPI1013698A2 (pt) métodos para tratamento com o uso de terapia de combinação
BRPI1005292A2 (pt) composição de decapagem e uso da composição
BRPI1005670A8 (pt) composições adjuvantes e processos de uso.
BR112013022166A2 (pt) composição com atividade antifúngica e antibacteriana e uso da composição
BR112012004281A2 (pt) uso de metformina tratamento e prevenção de câncer
CO6790239A1 (es) Vidrios blindados curvos con vidrios, vitro- cerámicos o cerámicos curvados mecánicamente en la capa externa
IT1403847B1 (it) Composizioni farmaceutiche comprendenti rifaximina e loro uso.
IT1398316B1 (it) Struttura di ruota piroettante, particolarmente per mobili e simili.
BRPI0914560A2 (pt) pestivírus atenuado
BRPI0913175A2 (pt) artigo antibalístico, e, uso do mesmo.
EA201490761A1 (ru) R(+)-n-формилпропаргиламиноиндан
BR112014009476A2 (pt) refletor, iluminador e uso do iluminador
CL2008000110A1 (es) Uso de compuestos derivados de piranona sustituidos para el tratamiento del sindrome metabolico; y compuestos derivados de piranona sustituidos.
BRPI0911772A2 (pt) composto, composição farmacêutica, e, uso do composto.
MA32321B1 (fr) Pregn-4-en-21, 17 carbolactones substitués sur le noyau c, et préparations pharmaceutiques contenant ces derniers
BR112013023575A2 (pt) “derivado de octaidrotienoquinolina, composição farmacêutica compreendendo o derivado, e uso destes”
BR112013012175A2 (pt) combinação, coadministração, uso e método
BR112013023616A2 (pt) dispositivo eletricamente operado e dinamicamente evacuável, e, uso de aerogéis orgânicos ou xerogéis orgânicos
ES2663096T3 (es) Métodos para el tratamiento del síndrome nefrótico y de afecciones relacionadas