WO2009037183A3 - Nukleinsäurehaltige kosmetische und/oder pharmazeutische zubereitung zur induktion antimikrobieller peptide in epithelialen deckgeweben - Google Patents

Nukleinsäurehaltige kosmetische und/oder pharmazeutische zubereitung zur induktion antimikrobieller peptide in epithelialen deckgeweben Download PDF

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Publication number
WO2009037183A3
WO2009037183A3 PCT/EP2008/062051 EP2008062051W WO2009037183A3 WO 2009037183 A3 WO2009037183 A3 WO 2009037183A3 EP 2008062051 W EP2008062051 W EP 2008062051W WO 2009037183 A3 WO2009037183 A3 WO 2009037183A3
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WO
WIPO (PCT)
Prior art keywords
epithelia
cosmetic
induction
antimicrobial peptides
nucleic acid
Prior art date
Application number
PCT/EP2008/062051
Other languages
English (en)
French (fr)
Other versions
WO2009037183A2 (de
Inventor
Stefan Kippenberger
August Bernd
Andreas Bock
Annette Dorn
Original Assignee
Henkel Ag & Co Kgaa
Stefan Kippenberger
August Bernd
Andreas Bock
Annette Dorn
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Henkel Ag & Co Kgaa, Stefan Kippenberger, August Bernd, Andreas Bock, Annette Dorn filed Critical Henkel Ag & Co Kgaa
Publication of WO2009037183A2 publication Critical patent/WO2009037183A2/de
Publication of WO2009037183A3 publication Critical patent/WO2009037183A3/de

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088—Compounds having three or more nucleosides or nucleotides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088—Compounds having three or more nucleosides or nucleotides
    • A61K31/712—Nucleic acids or oligonucleotides having modified sugars, i.e. other than ribose or 2'-deoxyribose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088—Compounds having three or more nucleosides or nucleotides
    • A61K31/7125—Nucleic acids or oligonucleotides having modified internucleoside linkage, i.e. other than 3'-5' phosphodiesters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088—Compounds having three or more nucleosides or nucleotides
    • A61K31/713—Double-stranded nucleic acids or oligonucleotides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/60—Sugars; Derivatives thereof
    • A61K8/606—Nucleosides; Nucleotides; Nucleic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A61Q17/005—Antimicrobial preparations
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biochemistry (AREA)
  • Dermatology (AREA)
  • Birds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Cosmetics (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Die vorliegende Erfindung betrifft kosmetische und/oder pharmazeutische Zubereitungen zur Behandlung epithelialen Deckgewebes durch Induktion antimikrobieller Peptide in dem behandelten epithelialen Deckgewebe sowie die Verwendung von Nukleinsäuren zur Induktion antimikrobieller Peptide in epithelialen Deckgeweben.
PCT/EP2008/062051 2007-09-14 2008-09-11 Nukleinsäurehaltige kosmetische und/oder pharmazeutische zubereitung zur induktion antimikrobieller peptide in epithelialen deckgeweben WO2009037183A2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102007044093A DE102007044093A1 (de) 2007-09-14 2007-09-14 Nukleinsäurehaltige kosmetische und/oder pharmazeutische Zubereitungen zur Induktion antimikrobieller Peptide in epithelialen Deckgeweben
DE102007044093.8 2007-09-14

Publications (2)

Publication Number Publication Date
WO2009037183A2 WO2009037183A2 (de) 2009-03-26
WO2009037183A3 true WO2009037183A3 (de) 2009-06-11

Family

ID=40348585

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2008/062051 WO2009037183A2 (de) 2007-09-14 2008-09-11 Nukleinsäurehaltige kosmetische und/oder pharmazeutische zubereitung zur induktion antimikrobieller peptide in epithelialen deckgeweben

Country Status (2)

Country Link
DE (1) DE102007044093A1 (de)
WO (1) WO2009037183A2 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102011077052A1 (de) 2011-06-07 2012-12-13 Beiersdorf Ag Verwendung von epsilon-Poly-L-Lysin zur Erhöhung der Bioverfügbarkeit antimikrobieller Peptide in menschlicher Haut.
ITMI20122263A1 (it) 2012-12-28 2014-06-29 Azienda Ospedaliero Universitaria Di Parma Nuovi peptidi cationici ciclici ad attività antimicrobica
WO2015198265A2 (en) * 2014-06-27 2015-12-30 I.C.F. S.R.L. Disinfectant and antimicrobial compositions, in particular for the veterinary field
RU2602298C2 (ru) * 2015-04-10 2016-11-20 Федеральное государственное бюджетное научное учреждение "Научно-исследовательский институт вакцин и сывороток им. И.И. Мечникова" (ФГБНУ НИИВС им. И.И. Мечникова) Способ определения совокупной активности антимикробных пептидов как маркера состояния местного иммунитета различных эпителиальных тканей
CN105106729A (zh) * 2015-09-28 2015-12-02 成都倍加特生物科技有限公司 一种治疗传染性红斑的内服药物及其制备方法
CN114317652A (zh) * 2021-12-16 2022-04-12 中国科学院兰州化学物理研究所 一种利用多孔聚合物分离材料从鱼籽多肽中分离纯化具有改善记忆功能的多肽的方法

Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001022990A2 (en) * 1999-09-27 2001-04-05 Coley Pharmaceutical Group, Inc. Methods related to immunostimulatory nucleic acid-induced interferon
WO2001054720A1 (en) * 2000-01-28 2001-08-02 Cistem Biotechnologies Gmbh Pharmaceutical composition for immunomodulation and preparation of vaccines comprising an antigen and an immunogenic oligodeoxynucleotide and a polycationic polymer as adjuvants
US20040001803A1 (en) * 2001-12-03 2004-01-01 Hancock Robert E.W. Effectors of innate immunity determination
WO2004012688A2 (de) * 2002-07-25 2004-02-12 Phenion Gmbh & Co. Kg Kosmetische oder pharmazeutische zubereitungen enthaltend nukleinsäuren auf der basis nicht-methylierter cpg-motive
WO2005025614A2 (en) * 2003-09-15 2005-03-24 Glaxo Group Limited Improvements in vaccination
WO2005063300A2 (de) * 2003-12-23 2005-07-14 Phenion Gmbh & Co. Kg Kosmetische oder pharmazeutische zubereitungen enthaltend superstrukturbildende nukleinsäure-sequenzen
DE202005001952U1 (de) * 2005-02-06 2006-08-31 Phenion Gmbh & Co. Kg Kosmetische oder pharmazeutische Zubereitungen enthaltend Nukleinsäuren, die zur Ausbildung von stem-loop-Sekundärstrukturen geeignete Sequenzen umfassen
EP1733735A2 (de) * 1998-05-22 2006-12-20 Ottawa Health Research Institute Verfahren und Produkte zur Induktion von mukosaler Immunität
WO2008135169A1 (de) * 2007-04-27 2008-11-13 Henkel Ag & Co. Kgaa Nukleinsäurehaltige kosmetische und/oder pharmazeutische zubereitungen zur behandlung epithelialen deckgewebes

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1165574B (de) 1960-08-08 1964-03-19 Dehydag Gmbh Verfahren zur Herstellung von als Emulgiermittel fuer Salbengrundlagen dienenden Mischestern
DE2024051C3 (de) 1970-05-16 1986-05-07 Henkel KGaA, 4000 Düsseldorf Verwendung der Veresterungsprodukte von Glycerin-Äthylenoxid-Addukten mit Fettsäuren als Rückfettungsmittel in kosmetischen Zubereitungen
LU68901A1 (de) 1973-11-30 1975-08-20
DE4426215A1 (de) 1994-07-23 1996-01-25 Merck Patent Gmbh Ketotricyclo [5.2.1.0] decan-Derivate
DE4426216A1 (de) 1994-07-23 1996-01-25 Merck Patent Gmbh Benzyliden-Norcampher-Derivate
ES2188883T3 (es) 1996-07-08 2003-07-01 Ciba Sc Holding Ag Derivados de triazina como filtro uv en productos antisolares.
DE19712033A1 (de) 1997-03-21 1998-09-24 Basf Ag Photostabile UV-Filter enthaltende kosmetische und pharmazeutische Zubereitungen
DE19740092A1 (de) 1997-09-12 1999-03-18 Ulrich Dr Med Hengge Liposomen und Verfahren zur Transfektion von Zellen
WO2002038150A1 (de) 2000-11-09 2002-05-16 Phenion Gmbh & Co. Kg Aktivatoren von peroxisom-proliferator-aktivierten rezeptoren alpha, beta als arzneimittel zur behandlung von immunologisch bedingten hautstörungen
DE102004039537A1 (de) 2004-08-13 2006-02-23 Phenion Gmbh & Co. Kg Vernetzte Kollagenmatrix zur Herstellung eines Hautäquivalentes
DE102005005642A1 (de) * 2005-02-06 2006-08-10 Phenion Gmbh & Co. Kg Kosmetische oder pharmazeutische Zubereitungen enthaltend Nukleinsäuren, die zur Ausbildung von stem-loop-Sekundärstrukturen geeignete Sequenzen umfassen

Patent Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1733735A2 (de) * 1998-05-22 2006-12-20 Ottawa Health Research Institute Verfahren und Produkte zur Induktion von mukosaler Immunität
WO2001022990A2 (en) * 1999-09-27 2001-04-05 Coley Pharmaceutical Group, Inc. Methods related to immunostimulatory nucleic acid-induced interferon
WO2001054720A1 (en) * 2000-01-28 2001-08-02 Cistem Biotechnologies Gmbh Pharmaceutical composition for immunomodulation and preparation of vaccines comprising an antigen and an immunogenic oligodeoxynucleotide and a polycationic polymer as adjuvants
US20040001803A1 (en) * 2001-12-03 2004-01-01 Hancock Robert E.W. Effectors of innate immunity determination
WO2004012688A2 (de) * 2002-07-25 2004-02-12 Phenion Gmbh & Co. Kg Kosmetische oder pharmazeutische zubereitungen enthaltend nukleinsäuren auf der basis nicht-methylierter cpg-motive
WO2005025614A2 (en) * 2003-09-15 2005-03-24 Glaxo Group Limited Improvements in vaccination
WO2005063300A2 (de) * 2003-12-23 2005-07-14 Phenion Gmbh & Co. Kg Kosmetische oder pharmazeutische zubereitungen enthaltend superstrukturbildende nukleinsäure-sequenzen
DE202005001952U1 (de) * 2005-02-06 2006-08-31 Phenion Gmbh & Co. Kg Kosmetische oder pharmazeutische Zubereitungen enthaltend Nukleinsäuren, die zur Ausbildung von stem-loop-Sekundärstrukturen geeignete Sequenzen umfassen
WO2008135169A1 (de) * 2007-04-27 2008-11-13 Henkel Ag & Co. Kgaa Nukleinsäurehaltige kosmetische und/oder pharmazeutische zubereitungen zur behandlung epithelialen deckgewebes

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
GLAESER REGINE ET AL: "Antimicrobial psoriasin (S100A7) protects human skin from Escherichia coli infection", NATURE IMMUNOLOGY, vol. 6, no. 1, January 2005 (2005-01-01), pages 57 - 64, XP002520407, ISSN: 1529-2908 *
HARDER JUERGEN ET AL: "Psoriatic scales: a promising source for the isolation of human skin-derivedantimicrobial proteins", JOURNAL OF LEUKOCYTE BIOLOGY, BIOLOGY, BETHESDA, vol. 77, no. 4, 1 April 2005 (2005-04-01), pages 476 - 486, XP009087974, ISSN: 0741-5400 *
JURK MARION ET AL: "Therapeutic applications of synthetic CpG oligodeoxynucleotides as TLR9 agonists for immune modulation", BIODRUGS, AUCKLAND, NZ, vol. 21, no. 6, 1 January 2007 (2007-01-01), pages 387 - 401, XP008096225, ISSN: 1173-8804 *
STEFAN KIPPENBERGER ET AL: "Detection of human beta defensin-1 and -2 by RT-competitive multiplex PCR", ARCHIVES OF DERMATOLOGICAL RESEARCH ; FOUNDED IN 1869 AS ARCHIV FÜR DERMATOLOGIE UND SYPHILIS, SPRINGER, BERLIN, DE, vol. 296, no. 11, 1 May 2005 (2005-05-01), pages 539 - 542, XP019341084, ISSN: 1432-069X *

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WO2009037183A2 (de) 2009-03-26
DE102007044093A1 (de) 2009-03-19

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