HK1116772A1 - Macrocylic inhibitors of hepatitis c virus - Google Patents

Macrocylic inhibitors of hepatitis c virus

Info

Publication number
HK1116772A1
HK1116772A1 HK08106769.8A HK08106769A HK1116772A1 HK 1116772 A1 HK1116772 A1 HK 1116772A1 HK 08106769 A HK08106769 A HK 08106769A HK 1116772 A1 HK1116772 A1 HK 1116772A1
Authority
HK
Hong Kong
Prior art keywords
hepatitis
virus
macrocylic
inhibitors
macrocylic inhibitors
Prior art date
Application number
HK08106769.8A
Other languages
English (en)
Inventor
Pierre Jean-Marie Bernard Raboisson
Kock Herman Augustinus De
Sandrine Marie Helene Vendeville
Lili Hu
Vreken Wim Van De
Gowan David Craig Mc
Abdellah Tahri
Dominique Louis Nestor Ghislain Surleraux
Kenneth Alan Simmen
Original Assignee
Tibotec Pharm Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=37036843&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HK1116772(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Tibotec Pharm Ltd filed Critical Tibotec Pharm Ltd
Publication of HK1116772A1 publication Critical patent/HK1116772A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/05—Dipeptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06139—Dipeptides with the first amino acid being heterocyclic
    • C07K5/06165—Dipeptides with the first amino acid being heterocyclic and Pro-amino acid; Derivatives thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Virology (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Pulmonology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
HK08106769.8A 2005-07-29 2008-06-18 Macrocylic inhibitors of hepatitis c virus HK1116772A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP05107067 2005-07-29
EP05107413 2005-08-11
PCT/EP2006/064813 WO2007014919A1 (en) 2005-07-29 2006-07-28 Macrocylic inhibitors of hepatitis c virus

Publications (1)

Publication Number Publication Date
HK1116772A1 true HK1116772A1 (en) 2009-01-02

Family

ID=37036843

Family Applications (1)

Application Number Title Priority Date Filing Date
HK08106769.8A HK1116772A1 (en) 2005-07-29 2008-06-18 Macrocylic inhibitors of hepatitis c virus

Country Status (28)

Country Link
US (1) US7989471B2 (ru)
EP (1) EP1912995B1 (ru)
JP (1) JP5426163B2 (ru)
KR (1) KR101074673B1 (ru)
CN (1) CN101233137B (ru)
AP (1) AP2473A (ru)
AR (1) AR055104A1 (ru)
AT (1) ATE517902T1 (ru)
AU (1) AU2006274858B2 (ru)
BR (1) BRPI0614670A2 (ru)
CA (1) CA2617095C (ru)
DK (1) DK1912995T3 (ru)
EA (1) EA014646B1 (ru)
GT (1) GT200600341A (ru)
HK (1) HK1116772A1 (ru)
IL (1) IL188283A (ru)
JO (1) JO2768B1 (ru)
MX (1) MX2008001395A (ru)
MY (1) MY152153A (ru)
NO (1) NO20081071L (ru)
NZ (1) NZ564541A (ru)
PE (1) PE20070221A1 (ru)
SG (1) SG163613A1 (ru)
SI (1) SI1912995T1 (ru)
SV (1) SV2008002639A (ru)
TW (1) TWI412534B (ru)
UY (1) UY29705A1 (ru)
WO (1) WO2007014919A1 (ru)

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PE20070211A1 (es) 2005-07-29 2007-05-12 Medivir Ab Compuestos macrociclicos como inhibidores del virus de hepatitis c
US7741281B2 (en) 2005-11-03 2010-06-22 Bristol-Myers Squibb Company Hepatitis C virus inhibitors
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EP2049474B1 (en) 2006-07-11 2015-11-04 Bristol-Myers Squibb Company Hepatitis c virus inhibitors
EP2374812B1 (en) 2006-07-13 2015-04-15 Achillion Pharmaceuticals, Inc. 4-amino-4-oxobutanoyl Peptides as Inhibitors of Viral Replication
US8343477B2 (en) 2006-11-01 2013-01-01 Bristol-Myers Squibb Company Inhibitors of hepatitis C virus
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US8003604B2 (en) 2006-11-16 2011-08-23 Bristol-Myers Squibb Company Hepatitis C virus inhibitors
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CA2705803A1 (en) 2007-11-14 2009-05-22 Enanta Pharmaceuticals, Inc. Macrocyclic tetrazolyl hepatitis c serine protease inhibitors
WO2009079353A1 (en) 2007-12-14 2009-06-25 Enanta Pharmaceuticals, Inc. Triazole-containing macrocyclic hcv serine protease inhibitors
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US7964560B2 (en) 2008-05-29 2011-06-21 Bristol-Myers Squibb Company Hepatitis C virus inhibitors
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US8563505B2 (en) 2008-09-29 2013-10-22 Bristol-Myers Squibb Company Hepatitis C virus inhibitors
US8044087B2 (en) 2008-09-29 2011-10-25 Bristol-Myers Squibb Company Hepatitis C virus inhibitors
AU2009324643B2 (en) 2008-12-10 2014-08-28 Achillion Pharmaceuticals, Inc. New 4-amino-4-oxobutanoyl peptides as inhibitors of viral replication
US8283310B2 (en) 2008-12-15 2012-10-09 Bristol-Myers Squibb Company Hepatitis C virus inhibitors
US8377962B2 (en) 2009-04-08 2013-02-19 Idenix Pharmaceuticals, Inc. Macrocyclic serine protease inhibitors
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BR112013016480A2 (pt) 2010-12-30 2016-09-20 Abbvie Inc macrocíclo da fenantridina inibadores da protease da serina da hepatite c
TW201309690A (zh) 2011-02-10 2013-03-01 Idenix Pharmaceuticals Inc 巨環絲胺酸蛋白酶抑制劑，其醫藥組合物及其於治療ｈｃｖ感染之用途
US8957203B2 (en) 2011-05-05 2015-02-17 Bristol-Myers Squibb Company Hepatitis C virus inhibitors
US10201584B1 (en) 2011-05-17 2019-02-12 Abbvie Inc. Compositions and methods for treating HCV
US8691757B2 (en) 2011-06-15 2014-04-08 Bristol-Myers Squibb Company Hepatitis C virus inhibitors
US9346785B2 (en) * 2012-01-11 2016-05-24 Abbvie Inc. Process for making HCV protease inhibitors
CN104822682A (zh) 2012-10-08 2015-08-05 艾伯维公司 用于制备hcv蛋白酶抑制剂的化合物
JP6154474B2 (ja) 2012-10-19 2017-06-28 ブリストル−マイヤーズ スクイブ カンパニーＢｒｉｓｔｏｌ−Ｍｙｅｒｓ Ｓｑｕｉｂｂ Ｃｏｍｐａｎｙ Ｃ型肝炎ウイルス阻害剤
EP2914598B1 (en) 2012-11-02 2017-10-18 Bristol-Myers Squibb Company Hepatitis c virus inhibitors
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Also Published As

Publication number Publication date
EA014646B1 (ru) 2010-12-30
CN101233137B (zh) 2014-05-07
KR20080041651A (ko) 2008-05-13
UY29705A1 (es) 2007-05-31
CA2617095A1 (en) 2007-02-08
AU2006274858A1 (en) 2007-02-08
AU2006274858B2 (en) 2012-05-24
CN101233137A (zh) 2008-07-30
DK1912995T3 (da) 2011-10-24
TWI412534B (zh) 2013-10-21
EP1912995B1 (en) 2011-07-27
MX2008001395A (es) 2008-04-16
US20100240698A1 (en) 2010-09-23
MY152153A (en) 2014-08-15
JO2768B1 (en) 2014-03-15
AP2473A (en) 2012-09-24
US7989471B2 (en) 2011-08-02
WO2007014919A1 (en) 2007-02-08
JP5426163B2 (ja) 2014-02-26
PE20070221A1 (es) 2007-04-16
ATE517902T1 (de) 2011-08-15
NZ564541A (en) 2010-03-26
TW200745165A (en) 2007-12-16
NO20081071L (no) 2008-04-25
IL188283A0 (en) 2008-04-13
EP1912995A1 (en) 2008-04-23
SG163613A1 (en) 2010-08-30
BRPI0614670A2 (pt) 2011-04-12
SI1912995T1 (sl) 2011-11-30
CA2617095C (en) 2014-05-13
AR055104A1 (es) 2007-08-08
EA200800484A1 (ru) 2008-06-30
IL188283A (en) 2016-12-29
SV2008002639A (es) 2008-07-23
JP2009502882A (ja) 2009-01-29
GT200600341A (es) 2007-02-26
KR101074673B1 (ko) 2011-10-19

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Legal Events

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PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20150728