HK1110782A1 - 4-phenyl-5-oxo-1,4,5,6,7,8-hexahydroqe inoline derivatives as medicaments for the treatment of infertility - Google Patents
4-phenyl-5-oxo-1,4,5,6,7,8-hexahydroqe inoline derivatives as medicaments for the treatment of infertilityInfo
- Publication number
- HK1110782A1 HK1110782A1 HK08105174A HK08105174A HK1110782A1 HK 1110782 A1 HK1110782 A1 HK 1110782A1 HK 08105174 A HK08105174 A HK 08105174A HK 08105174 A HK08105174 A HK 08105174A HK 1110782 A1 HK1110782 A1 HK 1110782A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- hexahydroqe
- inoline
- infertility
- medicaments
- oxo
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Endocrinology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Reproductive Health (AREA)
- Epidemiology (AREA)
- Diabetes (AREA)
- Pregnancy & Childbirth (AREA)
- Gynecology & Obstetrics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Quinoline Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP05103741 | 2005-05-04 | ||
| PCT/EP2006/061978 WO2006117371A1 (en) | 2005-05-04 | 2006-05-02 | 4-PHENYL-5-0X0-l,4,5,6,7,8-HEXAHYDR0QËIN0LINE DERIVATIVES AS MEDICAMENTS FOR THE TREATMENT OF INFERTILITY |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HK1110782A1 true HK1110782A1 (en) | 2008-07-25 |
Family
ID=34939698
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HK08105174A HK1110782A1 (en) | 2005-05-04 | 2008-05-08 | 4-phenyl-5-oxo-1,4,5,6,7,8-hexahydroqe inoline derivatives as medicaments for the treatment of infertility |
Country Status (31)
| Country | Link |
|---|---|
| US (1) | US8017782B2 (ru) |
| EP (1) | EP1879581B1 (ru) |
| JP (1) | JP5118631B2 (ru) |
| KR (1) | KR20080010445A (ru) |
| CN (1) | CN101212971B (ru) |
| AR (1) | AR054109A1 (ru) |
| AT (1) | ATE406895T1 (ru) |
| AU (1) | AU2006243194B2 (ru) |
| BR (1) | BRPI0611124A2 (ru) |
| CA (1) | CA2607106C (ru) |
| CY (1) | CY1108584T1 (ru) |
| DE (1) | DE602006002608D1 (ru) |
| DK (1) | DK1879581T3 (ru) |
| ES (1) | ES2313667T3 (ru) |
| HK (1) | HK1110782A1 (ru) |
| HR (1) | HRP20080488T3 (ru) |
| IL (1) | IL186831A (ru) |
| MX (1) | MX2007013754A (ru) |
| MY (1) | MY144609A (ru) |
| NO (1) | NO20075637L (ru) |
| NZ (1) | NZ562804A (ru) |
| PE (1) | PE20061371A1 (ru) |
| PL (1) | PL1879581T3 (ru) |
| PT (1) | PT1879581E (ru) |
| RS (1) | RS50614B (ru) |
| RU (1) | RU2403249C2 (ru) |
| SI (1) | SI1879581T1 (ru) |
| TW (1) | TW200716553A (ru) |
| UA (1) | UA92009C2 (ru) |
| WO (1) | WO2006117371A1 (ru) |
| ZA (1) | ZA200709096B (ru) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2361674T3 (es) * | 2005-05-04 | 2011-06-21 | N.V. Organon | Derivados de dihidropiridina. |
| UA92007C2 (ru) * | 2005-05-04 | 2010-09-27 | Н.В. Органон | Производные 4-фенил-5-оксо-1,4,5,6,7,8-гексагидрохинолина для лечения бесплодности |
| UA92008C2 (en) * | 2005-05-04 | 2010-09-27 | Н.В. Органон | 4-PHENYL-5-OXO-l,4,5,6,7,8-HEXAHYDROQUINOLINE DERIVATIVES AS MEDICAMENTS FOR THE TREATMENT OF INFERTILITY |
| TW200944523A (en) | 2008-02-08 | 2009-11-01 | Organon Nv | (Dihydro)pyrrolo[2,1-a]isoquinolines |
| US8071587B2 (en) * | 2009-05-27 | 2011-12-06 | N. V. Organon | (Dihydro)imidazoiso[5,1-A]quinolines |
| US8431564B2 (en) | 2009-07-29 | 2013-04-30 | Merck Sharp & Dohme B.V. | Ring-annulated dihydropyrrolo[2,1-α]isoquinolines |
| TW201116531A (en) | 2009-07-29 | 2011-05-16 | Organon Nv | Ring-annulated dihydropyrrolo[2,1-a]isoquinolines |
| TW201116515A (en) | 2009-07-31 | 2011-05-16 | Organon Nv | Dihydrobenzoindazoles |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1070162B (de) | 1959-12-03 | Farbwerke Hoechst Aktiengesellschaft vormals Meister Lucius &. Brüning, Frankfurt/M | Verfahren zur Herstellung von 5 - Brom - 3 - nitro - 4 - hydroxybenzaldehyd bzw. 5 - Chlor - 3 - nitro - 4 - hydroxybenzaldehyd | |
| GB9318935D0 (en) * | 1992-10-20 | 1993-10-27 | Zeneca Ltd | Heterocyclic derivatives |
| US5455253A (en) * | 1992-10-20 | 1995-10-03 | Zeneca Limited | Heterocyclic derivatives |
| DE4430639A1 (de) * | 1994-08-29 | 1996-03-07 | Bayer Ag | Verwendung von 5-substituierten Pyridin- und Hexahydrochinolin-3-carbonsäurederivaten |
| GB9515445D0 (en) | 1995-07-27 | 1995-09-27 | Pharmacia Spa | Dihydropyridine and pyridine derivatives and process for their preparation |
| DE69623655T2 (de) * | 1995-10-19 | 2003-04-24 | Takeda Chemical Industries, Ltd. | Chinolinderivate als gnrh antagonisten |
| US6593335B1 (en) | 1997-12-18 | 2003-07-15 | Abbott Laboratories | Potassium channel openers |
| IL141063A (en) | 1998-08-07 | 2005-06-19 | Applied Research Systems | Derivatives of pyrrolidine-2-carboxylic acid and piperidine-2-carboxylic acids and pharmaceutical compositions comprising said derivatives for treating infertility |
| JP2004505051A (ja) | 2000-07-27 | 2004-02-19 | スミスクライン ビーチャム コーポレーション | 卵胞刺激ホルモン活性のアゴニスト |
| CZ20042A3 (en) * | 2001-07-02 | 2004-04-14 | Akzo Nobel N. V. | Tetrahydroquinoline derivatives |
| JP2003026630A (ja) | 2001-07-13 | 2003-01-29 | Taoka Chem Co Ltd | カラーカプラー中間体用カルボン酸クロリド類の製造法 |
| TWI322012B (en) | 2002-12-20 | 2010-03-21 | Organon Nv | Tetrahydroquinoline derivatives |
| ES2361674T3 (es) * | 2005-05-04 | 2011-06-21 | N.V. Organon | Derivados de dihidropiridina. |
| UA92008C2 (en) * | 2005-05-04 | 2010-09-27 | Н.В. Органон | 4-PHENYL-5-OXO-l,4,5,6,7,8-HEXAHYDROQUINOLINE DERIVATIVES AS MEDICAMENTS FOR THE TREATMENT OF INFERTILITY |
| UA92007C2 (ru) * | 2005-05-04 | 2010-09-27 | Н.В. Органон | Производные 4-фенил-5-оксо-1,4,5,6,7,8-гексагидрохинолина для лечения бесплодности |
-
2006
- 2006-02-05 UA UAA200711804A patent/UA92009C2/ru unknown
- 2006-05-02 SI SI200630120T patent/SI1879581T1/sl unknown
- 2006-05-02 CN CN2006800235439A patent/CN101212971B/zh not_active Expired - Fee Related
- 2006-05-02 DE DE602006002608T patent/DE602006002608D1/de active Active
- 2006-05-02 AT AT06754954T patent/ATE406895T1/de active
- 2006-05-02 ES ES06754954T patent/ES2313667T3/es active Active
- 2006-05-02 DK DK06754954T patent/DK1879581T3/da active
- 2006-05-02 NZ NZ562804A patent/NZ562804A/en not_active IP Right Cessation
- 2006-05-02 MX MX2007013754A patent/MX2007013754A/es active IP Right Grant
- 2006-05-02 AU AU2006243194A patent/AU2006243194B2/en not_active Ceased
- 2006-05-02 WO PCT/EP2006/061978 patent/WO2006117371A1/en active Application Filing
- 2006-05-02 KR KR1020077027874A patent/KR20080010445A/ko not_active Application Discontinuation
- 2006-05-02 EP EP06754954A patent/EP1879581B1/en active Active
- 2006-05-02 JP JP2008509437A patent/JP5118631B2/ja not_active Expired - Fee Related
- 2006-05-02 RU RU2007144984/04A patent/RU2403249C2/ru not_active IP Right Cessation
- 2006-05-02 PT PT06754954T patent/PT1879581E/pt unknown
- 2006-05-02 PL PL06754954T patent/PL1879581T3/pl unknown
- 2006-05-02 BR BRPI0611124-6A patent/BRPI0611124A2/pt not_active IP Right Cessation
- 2006-05-02 CA CA2607106A patent/CA2607106C/en not_active Expired - Fee Related
- 2006-05-02 RS RSP-2008/0457A patent/RS50614B/sr unknown
- 2006-05-02 US US11/912,756 patent/US8017782B2/en active Active
- 2006-05-03 MY MYPI20062028A patent/MY144609A/en unknown
- 2006-05-03 PE PE2006000466A patent/PE20061371A1/es not_active Application Discontinuation
- 2006-05-03 AR ARP060101781A patent/AR054109A1/es unknown
- 2006-05-03 TW TW095115776A patent/TW200716553A/zh unknown
-
2007
- 2007-10-22 ZA ZA200709096A patent/ZA200709096B/xx unknown
- 2007-10-22 IL IL186831A patent/IL186831A/en not_active IP Right Cessation
- 2007-11-06 NO NO20075637A patent/NO20075637L/no not_active Application Discontinuation
-
2008
- 2008-05-08 HK HK08105174A patent/HK1110782A1/xx not_active IP Right Cessation
- 2008-09-30 HR HR20080488T patent/HRP20080488T3/xx unknown
- 2008-11-20 CY CY20081101342T patent/CY1108584T1/el unknown
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DK3872059T3 (en) | Process for the preparation of 2,3,3,3 tetrahydrofluoropropene | |
| ZA200709090B (en) | 4-phenyl-5-oxo-1,4,5,6,7,8-hexahydroquinoline derivatives as medicaments for the treatment of infertility | |
| ZA200709094B (en) | 4-phenyl-5-oxo-1,4,5,6,7,8-hexahydroquinoline derivatives as medicaments for the treatment of infertility | |
| IL191832A0 (en) | Pyridiazinone derivatives for the treatment of tumours | |
| IL191907A0 (en) | Azepinoindole derivatives as pharmaceutical agents | |
| IL187235A0 (en) | 2,6 quinolinyl derivatives, processes for preparing them and their use as medicament | |
| IL179758A0 (en) | Substituted tetrahydro - 2h - isoquinolin - 1 - one derivatives, method for the production thereof, and use of the same as medicaments | |
| IL187904A (en) | Use of quinoline derivatives for the preparation of bacterial preparations for the treatment of bacteria caused by bacteria | |
| HK1110782A1 (en) | 4-phenyl-5-oxo-1,4,5,6,7,8-hexahydroqe inoline derivatives as medicaments for the treatment of infertility | |
| SI2024368T1 (sl) | Derivati 6,7,8,9-tetrahidro-5h-pirimido(4,5-d)azepin-4-il)-amina kot modulatorji trpv 1 za zdravljenje boleäśine | |
| TWI315305B (en) | Piperidin-4-yl-amide derivatives,pharmaceutical compositions comprising the same,process for preparing the same and the use thereof | |
| WO2009071689A3 (de) | 5-halogen-substituierte oxindol-derivate und ihre verwendung zur behandlung von vasopressin-abhängigen erkrankungen | |
| IL196206A0 (en) | Isoindoline derivatives for the treatment of arrhythmias | |
| PL1959957T3 (pl) | Pochodne pirymidyloaminobenzamidu do leczenia neurowłókniakowatości | |
| IL190596A0 (en) | 9-chloro-15-deoxyprostaglandin derivatives, process for their preparation and their use as medicaments | |
| IL213474A0 (en) | Processes for the preparation of cyclopropyl-amide derivatives | |
| PL2099765T3 (pl) | 5-, 6- lub 7-podstawione pochodne 3-aryloizochinolinoaminy jako środki przeciwnowotworowe | |
| EP1996192A4 (en) | PROCESS FOR PREPARING 3,4-SUBSTITUTED THIAZOLIDIN-2-ONES IN 3,4 | |
| IL186457A0 (en) | Process for the preparation of 9,10-dehydro-12,13-desoxyepothilone derivatives | |
| ZA200710259B (en) | 2,6 quinolinyl derivatives, processes for preparing them and their use as medicament | |
| ZA200706710B (en) | 6-Phenylhex-5-enoic acid derivatives, processes for the preparation thereof, pharmaceutical compositions them, and therapeutic uses thereof | |
| EP1915380A4 (en) | PROCESS FOR THE SYNTHESIS OF N, N'-DISUBSTITUTED OXABISPIDINES |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PC | Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee) |
Effective date: 20120502 |