HK1090362A1 - Heterocyclic methyl sulfone derivative - Google Patents
Heterocyclic methyl sulfone derivativeInfo
- Publication number
- HK1090362A1 HK1090362A1 HK06110974A HK06110974A HK1090362A1 HK 1090362 A1 HK1090362 A1 HK 1090362A1 HK 06110974 A HK06110974 A HK 06110974A HK 06110974 A HK06110974 A HK 06110974A HK 1090362 A1 HK1090362 A1 HK 1090362A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- methyl sulfone
- sulfone derivative
- heterocyclic methyl
- heterocyclic
- derivative
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/28—Radicals substituted by singly-bound oxygen or sulphur atoms
- C07D213/30—Oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/095—Sulfur, selenium, or tellurium compounds, e.g. thiols
- A61K31/10—Sulfides; Sulfoxides; Sulfones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C317/00—Sulfones; Sulfoxides
- C07C317/14—Sulfones; Sulfoxides having sulfone or sulfoxide groups bound to carbon atoms of six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyridine Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Pyrane Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
- Thiazole And Isothizaole Compounds (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2003187796 | 2003-06-30 | ||
JP2004099151 | 2004-03-30 | ||
PCT/JP2004/009132 WO2005000798A1 (ja) | 2003-06-30 | 2004-06-29 | 複素環メチルスルホン誘導体 |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1090362A1 true HK1090362A1 (en) | 2006-12-22 |
Family
ID=33554493
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK06110974A HK1090362A1 (en) | 2003-06-30 | 2006-10-04 | Heterocyclic methyl sulfone derivative |
Country Status (14)
Country | Link |
---|---|
US (1) | US7932271B2 (ru) |
EP (1) | EP1640366A4 (ru) |
JP (1) | JP4523914B2 (ru) |
KR (1) | KR20060066057A (ru) |
AU (1) | AU2004251987C1 (ru) |
CA (1) | CA2526487A1 (ru) |
HK (1) | HK1090362A1 (ru) |
IL (1) | IL172139A0 (ru) |
MX (1) | MXPA05013631A (ru) |
NO (1) | NO20055921L (ru) |
PL (1) | PL379466A1 (ru) |
RU (1) | RU2336270C2 (ru) |
TW (1) | TWI328005B (ru) |
WO (1) | WO2005000798A1 (ru) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB0108591D0 (en) | 2001-04-05 | 2001-05-23 | Merck Sharp & Dohme | Therapeutic agents |
GB0120347D0 (en) | 2001-08-21 | 2001-10-17 | Merck Sharp & Dohme | Therapeutic agents |
RU2304140C2 (ru) * | 2001-12-27 | 2007-08-10 | Дайити Фармасьютикал Ко., Лтд. | ИНГИБИТОРЫ ПРОДУЦИРОВАНИЯ / СЕКРЕЦИИ β-АМИЛОИДНОГО БЕЛКА |
GB0223039D0 (en) | 2002-10-04 | 2002-11-13 | Merck Sharp & Dohme | Therapeutic compounds |
CA2526487A1 (en) | 2003-06-30 | 2005-01-06 | Daiichi Pharmaceutical Co., Ltd. | Heterocyclic methyl sulfone derivative |
KR20070116865A (ko) * | 2005-04-08 | 2007-12-11 | 다이이찌 산쿄 가부시키가이샤 | 피리딜메틸설폰 유도체 |
RU2446158C9 (ru) * | 2006-06-22 | 2012-06-20 | Астразенека Аб | Замещенные изоиндолы в качестве ингибиторов васе и их применение |
JP2008115166A (ja) * | 2006-10-10 | 2008-05-22 | Daiichi Sankyo Co Ltd | ピリジルフェニルメチルスルホン誘導体 |
US20100183513A1 (en) | 2006-11-24 | 2010-07-22 | Wolfgang Froestl | N-(methyl) -1h-pyrazol-3-amine, n-(methyl)-pyridin-2-amine and n-(methyl)-thiazol-2-amine derivatives for the treatment of diseases associated with amyloid or amyloid-like proteins, like e.g. alzheimer's |
TW200920362A (en) | 2007-09-11 | 2009-05-16 | Daiichi Sankyo Co Ltd | Alkylsulfone derivatives |
WO2009045382A1 (en) | 2007-10-04 | 2009-04-09 | Merck & Co., Inc. | Substituted aryl sulfone derivatives as calcium channel blockers |
EP2311823A1 (en) | 2009-10-15 | 2011-04-20 | AC Immune S.A. | 2,6-Diaminopyridine compounds for treating diseases associated with amyloid proteins or for treating ocular diseases |
UA103272C2 (ru) * | 2009-12-11 | 2013-09-25 | Ф. Хоффманн-Ля Рош Аг | 2-амино-5,5-дифтор-5,6-дигидро-4h-оксазины как ингибиторы bace1 и/или bace2 |
US9120752B2 (en) | 2010-07-16 | 2015-09-01 | Purdue Pharma, L.P. | Pyridine compounds as sodium channel blockers |
WO2013136170A1 (en) | 2012-03-16 | 2013-09-19 | Purdue Pharma L.P. | Substituted pyridines as sodium channel blockers |
EP2935257B1 (en) | 2012-12-20 | 2018-02-07 | Purdue Pharma LP | Cyclic sulfonamides as sodium channel blockers |
US10730866B2 (en) | 2014-04-07 | 2020-08-04 | Purdue Pharma L.P. | Indole derivatives and use thereof |
WO2017168464A1 (en) * | 2016-03-30 | 2017-10-05 | Nikon Corporation | Curable composition, cured product and optical member |
Family Cites Families (48)
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US3849423A (en) * | 1971-03-22 | 1974-11-19 | Lilly Co Eli | 3-benzylpyridines |
US4055652A (en) | 1975-07-07 | 1977-10-25 | Syntex (U.S.A.) Inc. | 1-[β(R-thio)phenethyl]imidazoles and derivatives thereof |
ZA765075B (en) | 1975-09-25 | 1977-08-31 | American Cyanamid Co | Hypolipemic compounds and method of treatment |
US4116665A (en) | 1976-04-02 | 1978-09-26 | Eli Lilly And Company | Method of regulating the growth of aquatic weeds with pyridine derivatives |
FR2375228A1 (fr) | 1976-12-23 | 1978-07-21 | Parcor | Nouveaux benzothiophenes, leurs procedes de preparation et leur application notamment comme hypolipemiants et hypocholesterolemiants |
DE2724684A1 (de) | 1977-06-01 | 1978-12-14 | Basf Ag | Triazolsubstituierte schwefelverbindungen |
DE2735314A1 (de) | 1977-08-05 | 1979-02-22 | Basf Ag | Alpha-azolylsulfide und deren derivate |
US4675316A (en) * | 1978-03-10 | 1987-06-23 | Rohm And Haas Company | Substituted azoylmethylarylsulfides and derivatives and pesticidal use thereof |
ZA794030B (en) * | 1978-08-08 | 1980-07-30 | Sterling Drug Inc | Aryl sulfinic acid derivatives of aliphatic,aromatic or heterocyclic compounds |
US4379921A (en) | 1980-08-21 | 1983-04-12 | Sumitomo Chemical Company, Limited | Production of triazolylvinyl ketones |
FR2509725A1 (fr) | 1981-07-15 | 1983-01-21 | Choay Sa | (hydroxyalkyl)phenylsulfures, leurs procedes de preparation et compositions pharmaceutiques les contenant |
EP0117485A3 (de) | 1983-02-28 | 1985-01-23 | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft | Pyridin-, Pyrazin- und Pyrimidinderivate und deren Verwendung als fungizide Wirkstoffe |
DE3406908A1 (de) | 1984-02-25 | 1985-09-05 | Hoechst Ag, 6230 Frankfurt | Neue triazolylalkylderivate, verfahren zu ihrer herstellung sowie ihre verwendung als pflanzenbehandlungsmittel |
JPS6239563A (ja) | 1985-08-13 | 1987-02-20 | Hokko Chem Ind Co Ltd | β−ニトロフエネチル誘導体および農園芸用殺菌剤 |
US5359078A (en) | 1989-05-19 | 1994-10-25 | The United States Of America As Represented By The Department Of Health And Human Services | Signal transduction inhibitor compounds |
DE4215437A1 (de) | 1992-05-11 | 1993-11-18 | Paul Prof Dr Messinger | Darstellung von Alkylacylaten mit ß-ständigen elektronenziehenden Resten im Alkylteil |
JPH0625168A (ja) * | 1992-07-10 | 1994-02-01 | Nippon Bayeragrochem Kk | 殺菌性ベンジルピリジン類 |
JPH0656780A (ja) * | 1992-08-01 | 1994-03-01 | Nippon Bayeragrochem Kk | 殺菌性α−置換ベンジルピリジン類 |
DE19521355A1 (de) * | 1995-06-12 | 1996-12-19 | Hoechst Schering Agrevo Gmbh | Sulfonamide, Verfahren zu deren Herstellung und ihre Verwendung als Herbizide und Pflanzenwachstumsregulatoren |
JPH0995444A (ja) | 1995-10-02 | 1997-04-08 | Teijin Ltd | アミロイド蛋白凝集阻害剤 |
JP3868354B2 (ja) * | 1997-02-27 | 2007-01-17 | 武田薬品工業株式会社 | アミン誘導体、その製造法および剤 |
ATE390404T1 (de) | 1997-02-27 | 2008-04-15 | Takeda Pharmaceutical | Aminderivate, ihre herstellung und verwendung als inhibitoren der produktion von amyloid-beta |
GB9902938D0 (en) * | 1999-02-10 | 1999-03-31 | Novartis Ag | Organic compounds |
KR20020006626A (ko) | 1999-02-26 | 2002-01-23 | 폴락 돈나 엘. | 신규한 술폰아미드 화합물 및 그의 용도 |
CA2404125C (en) | 2000-03-20 | 2011-01-25 | Merck Sharp & Dohme Limited | Sulphonamido-substituted bridged bicycloalkyl derivatives |
WO2001094318A2 (en) * | 2000-06-05 | 2001-12-13 | Ortho-Mcneil Pharmaceutical, Inc. | Method for synthesis of substituted azole libraries |
HUP0303857A3 (en) * | 2000-12-13 | 2007-07-30 | Wyeth Corp | Heterocyclic sulifonamide inhibitors of beta amyloid production |
GB0108591D0 (en) | 2001-04-05 | 2001-05-23 | Merck Sharp & Dohme | Therapeutic agents |
GB0108592D0 (en) | 2001-04-05 | 2001-05-23 | Merck Sharp & Dohme | Therapeutic agents |
MXPA04001016A (es) | 2001-08-03 | 2004-05-27 | Schering Corp | Derivados de sulfonamida como inhibidores de la gamma secretasa. |
AU2002324582B9 (en) | 2001-08-03 | 2006-02-16 | Schering Corporation | Novel gamma secretase inhibitors |
EA006225B1 (ru) | 2001-08-21 | 2005-10-27 | Мерк Шарп Энд Домэ Лимитед | Новые циклогексилсульфоны |
PL204281B1 (pl) | 2001-12-20 | 2009-12-31 | Bristol Myers Squibb Co | Pochodna α-(N-sulfonamido)-acetamidu jako inhibitor ß-amyloidu oraz kompozycja farmaceutyczna |
RU2304140C2 (ru) | 2001-12-27 | 2007-08-10 | Дайити Фармасьютикал Ко., Лтд. | ИНГИБИТОРЫ ПРОДУЦИРОВАНИЯ / СЕКРЕЦИИ β-АМИЛОИДНОГО БЕЛКА |
DE10201392A1 (de) | 2002-01-16 | 2003-07-31 | Bayer Ag | Phenylsulfoxide und-sulfone |
TW200302717A (en) | 2002-02-06 | 2003-08-16 | Schering Corp | Novel gamma secretase inhibitors |
DE60328182D1 (de) | 2002-05-01 | 2009-08-13 | Merck Sharp & Dohme | Heteroaryl substituierte spirocyclische sulfamide zur hemmung von gamma sekretase |
GB0209991D0 (en) | 2002-05-01 | 2002-06-12 | Merck Sharp & Dohme | Therapeutic agents |
GB0209995D0 (en) | 2002-05-01 | 2002-06-12 | Merck Sharp & Dohme | Therapeutic agents |
GB0209997D0 (en) | 2002-05-01 | 2002-06-12 | Merck Sharp & Dohme | Therapeutic agents |
BR0311767A (pt) | 2002-06-11 | 2005-03-08 | Wyeth Corp | Compostos inibidores de sulfonamida substituìda da produção de beta amilóide, suas composições e usos |
US7384941B2 (en) * | 2002-08-23 | 2008-06-10 | Eli Lilly And Company | 2-(phenoxymethyl)-and 2-(phenylthiomethyl)-morpholine derivatives for use as selective norepinephrine reuptake inhibitors |
GB0223038D0 (en) | 2002-10-04 | 2002-11-13 | Merck Sharp & Dohme | Therapeutic compounds |
GB0223039D0 (en) | 2002-10-04 | 2002-11-13 | Merck Sharp & Dohme | Therapeutic compounds |
GB0223040D0 (en) | 2002-10-04 | 2002-11-13 | Merck Sharp & Dohme | Therapeutic compounds |
GB0225475D0 (en) | 2002-11-01 | 2002-12-11 | Merck Sharp & Dohme | Therapeutic agents |
GB0225474D0 (en) | 2002-11-01 | 2002-12-11 | Merck Sharp & Dohme | Therapeutic agents |
CA2526487A1 (en) | 2003-06-30 | 2005-01-06 | Daiichi Pharmaceutical Co., Ltd. | Heterocyclic methyl sulfone derivative |
-
2004
- 2004-06-29 CA CA002526487A patent/CA2526487A1/en not_active Abandoned
- 2004-06-29 MX MXPA05013631A patent/MXPA05013631A/es unknown
- 2004-06-29 EP EP04746601A patent/EP1640366A4/en not_active Withdrawn
- 2004-06-29 AU AU2004251987A patent/AU2004251987C1/en not_active Ceased
- 2004-06-29 RU RU2005141552/04A patent/RU2336270C2/ru not_active IP Right Cessation
- 2004-06-29 US US10/561,838 patent/US7932271B2/en not_active Expired - Fee Related
- 2004-06-29 JP JP2005511074A patent/JP4523914B2/ja not_active Expired - Fee Related
- 2004-06-29 WO PCT/JP2004/009132 patent/WO2005000798A1/ja active Application Filing
- 2004-06-29 KR KR1020057025070A patent/KR20060066057A/ko not_active Application Discontinuation
- 2004-06-29 PL PL379466A patent/PL379466A1/pl not_active Application Discontinuation
- 2004-06-30 TW TW093119651A patent/TWI328005B/zh not_active IP Right Cessation
-
2005
- 2005-11-23 IL IL172139A patent/IL172139A0/en unknown
- 2005-12-13 NO NO20055921A patent/NO20055921L/no not_active Application Discontinuation
-
2006
- 2006-10-04 HK HK06110974A patent/HK1090362A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
TWI328005B (en) | 2010-08-01 |
KR20060066057A (ko) | 2006-06-15 |
AU2004251987C1 (en) | 2010-11-18 |
WO2005000798A1 (ja) | 2005-01-06 |
CA2526487A1 (en) | 2005-01-06 |
JPWO2005000798A1 (ja) | 2006-08-03 |
AU2004251987B2 (en) | 2010-07-01 |
PL379466A1 (pl) | 2006-09-18 |
RU2005141552A (ru) | 2006-06-27 |
JP4523914B2 (ja) | 2010-08-11 |
US7932271B2 (en) | 2011-04-26 |
RU2336270C2 (ru) | 2008-10-20 |
AU2004251987A1 (en) | 2005-01-06 |
US20060241302A1 (en) | 2006-10-26 |
AU2004251987B8 (en) | 2010-07-22 |
EP1640366A4 (en) | 2009-05-13 |
MXPA05013631A (es) | 2006-02-24 |
IL172139A0 (en) | 2006-04-10 |
NO20055921L (no) | 2006-01-24 |
TW200523251A (en) | 2005-07-16 |
EP1640366A1 (en) | 2006-03-29 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PC | Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee) |
Effective date: 20130629 |