FR2375228A1 - Nouveaux benzothiophenes, leurs procedes de preparation et leur application notamment comme hypolipemiants et hypocholesterolemiants - Google Patents
Nouveaux benzothiophenes, leurs procedes de preparation et leur application notamment comme hypolipemiants et hypocholesterolemiantsInfo
- Publication number
- FR2375228A1 FR2375228A1 FR7735387A FR7735387A FR2375228A1 FR 2375228 A1 FR2375228 A1 FR 2375228A1 FR 7735387 A FR7735387 A FR 7735387A FR 7735387 A FR7735387 A FR 7735387A FR 2375228 A1 FR2375228 A1 FR 2375228A1
- Authority
- FR
- France
- Prior art keywords
- new
- application
- preparation
- hypolipemiants
- hypocholesterolemiants
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
- C07D295/182—Radicals derived from carboxylic acids
- C07D295/185—Radicals derived from carboxylic acids from aliphatic carboxylic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
- C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/092—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings with aromatic radicals attached to the chain
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/62—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
- C07D333/64—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/62—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
- C07D333/66—Nitrogen atoms not forming part of a nitro radical
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
Abstract
Nouveaux benzothiophènes, leurs procédés de préparation et leur application notamment comme hypolipémiants et hypocholesterolémiants. a. Benzothiophènes. b. De formule :
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AT958776A AT345814B (de) | 1976-12-23 | 1976-12-23 | Verfahren zur herstellung von neuen n- substituierten 2-phenyl-benzo(b)thiophen-3-amin-derivaten und ihren salzen |
AT652777A ATA652777A (de) | 1977-09-12 | 1977-09-12 | Verfahren zur herstellung von neuen n,n- -disubstituierten 2-phenyl-benzo(b)thiophen-3- -amin-derivaten und ihren salzen |
AT652877 | 1977-09-12 |
Publications (2)
Publication Number | Publication Date |
---|---|
FR2375228A1 true FR2375228A1 (fr) | 1978-07-21 |
FR2375228B1 FR2375228B1 (fr) | 1981-01-16 |
Family
ID=27150647
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR7735387A Granted FR2375228A1 (fr) | 1976-12-23 | 1977-11-24 | Nouveaux benzothiophenes, leurs procedes de preparation et leur application notamment comme hypolipemiants et hypocholesterolemiants |
Country Status (16)
Country | Link |
---|---|
US (1) | US4157399A (fr) |
JP (1) | JPS5384962A (fr) |
AR (1) | AR217095A1 (fr) |
AU (1) | AU511826B2 (fr) |
BE (1) | BE862097A (fr) |
CA (1) | CA1120934A (fr) |
CH (1) | CH633552A5 (fr) |
DE (1) | DE2757422A1 (fr) |
ES (1) | ES465233A1 (fr) |
FR (1) | FR2375228A1 (fr) |
GB (1) | GB1586486A (fr) |
IE (1) | IE46097B1 (fr) |
LU (1) | LU78739A1 (fr) |
NL (1) | NL7714235A (fr) |
NZ (1) | NZ185880A (fr) |
SE (1) | SE433213B (fr) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3637223A1 (de) * | 1986-11-03 | 1988-05-05 | Bayer Ag | Verfahren zur herstellung von thiophenverbindungen |
NZ250916A (en) * | 1993-02-27 | 1995-08-28 | Nihon Nohyaku Co Ltd | N-heteroaryl-n'-phenylureas, their use as acat inhibitors |
CA2214919A1 (fr) * | 1996-09-24 | 1998-03-24 | Kenneth Lee Hauser | Composes de benzothiophene, intermediaires, procedes, compositions et methodes |
AU2001286392A1 (en) * | 2000-08-25 | 2002-03-13 | Eli Lilly And Company | Process for preparing 2-phenyl-3-aminobenzothiophenes |
US20040044224A1 (en) * | 2001-08-21 | 2004-03-04 | Conrad Preston Charles | Process for preparing 2-phenyl-3-aminobenzothiophenes |
CA2471943C (fr) * | 2001-12-27 | 2011-09-20 | Daiichi Pharmaceutical Co., Ltd. | Inhibiteurs de la production-secretion de la proteine amyloide-.beta. |
PL379466A1 (pl) * | 2003-06-30 | 2006-09-18 | Daiichi Sankyo Company , Limited | Heterocykliczne pochodne metylosulfonu |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AT316543B (de) * | 1972-08-21 | 1974-07-10 | Sauter Dr Fritz | Verfahren zur Herstellung von neuen, basisch substituierten 2-Phenyl-2-3-dihydro-benzo[b]-thiophen-1,1-dioxyd-Derivaten und ihren Salzen |
-
1977
- 1977-11-24 FR FR7735387A patent/FR2375228A1/fr active Granted
- 1977-11-29 IE IE2419/77A patent/IE46097B1/en unknown
- 1977-12-05 US US05/857,134 patent/US4157399A/en not_active Expired - Lifetime
- 1977-12-06 NZ NZ185880A patent/NZ185880A/xx unknown
- 1977-12-20 ES ES465233A patent/ES465233A1/es not_active Expired
- 1977-12-21 LU LU78739A patent/LU78739A1/xx unknown
- 1977-12-21 BE BE183659A patent/BE862097A/fr not_active IP Right Cessation
- 1977-12-21 AU AU31810/77A patent/AU511826B2/en not_active Expired
- 1977-12-21 CH CH1580977A patent/CH633552A5/fr not_active IP Right Cessation
- 1977-12-22 NL NL7714235A patent/NL7714235A/xx not_active Application Discontinuation
- 1977-12-22 GB GB53524/77A patent/GB1586486A/en not_active Expired
- 1977-12-22 SE SE7714663A patent/SE433213B/xx unknown
- 1977-12-22 DE DE19772757422 patent/DE2757422A1/de not_active Withdrawn
- 1977-12-22 JP JP15502277A patent/JPS5384962A/ja active Pending
- 1977-12-23 CA CA000293814A patent/CA1120934A/fr not_active Expired
- 1977-12-23 AR AR270497A patent/AR217095A1/es active
Non-Patent Citations (1)
Title |
---|
CA1976 * |
Also Published As
Publication number | Publication date |
---|---|
AU511826B2 (en) | 1980-09-04 |
CH633552A5 (fr) | 1982-12-15 |
IE46097B1 (en) | 1983-02-23 |
GB1586486A (en) | 1981-03-18 |
DE2757422A1 (de) | 1978-06-29 |
SE433213B (sv) | 1984-05-14 |
AU3181077A (en) | 1979-06-28 |
AR217095A1 (es) | 1980-02-29 |
LU78739A1 (fr) | 1978-04-17 |
NZ185880A (en) | 1979-12-11 |
IE46097L (en) | 1978-06-23 |
FR2375228B1 (fr) | 1981-01-16 |
ES465233A1 (es) | 1979-06-01 |
CA1120934A (fr) | 1982-03-30 |
NL7714235A (nl) | 1978-06-27 |
US4157399A (en) | 1979-06-05 |
SE7714663L (sv) | 1978-06-24 |
JPS5384962A (en) | 1978-07-26 |
BE862097A (fr) | 1978-06-21 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
ST | Notification of lapse |