GB0315870D0 - Heterocyclic derivatives - Google Patents

Heterocyclic derivatives

Info

Publication number
GB0315870D0
GB0315870D0 GBGB0315870.6A GB0315870A GB0315870D0 GB 0315870 D0 GB0315870 D0 GB 0315870D0 GB 0315870 A GB0315870 A GB 0315870A GB 0315870 D0 GB0315870 D0 GB 0315870D0
Authority
GB
United Kingdom
Prior art keywords
heterocyclic derivatives
heterocyclic
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
GBGB0315870.6A
Other versions
GB2392910A (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
Original Assignee
Bayer AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0220962A external-priority patent/GB0220962D0/en
Application filed by Bayer AG filed Critical Bayer AG
Priority to GB0315870A priority Critical patent/GB2392910A/en
Publication of GB0315870D0 publication Critical patent/GB0315870D0/en
Priority to ARP030103093A priority patent/AR042179A1/en
Priority to PCT/EP2003/009525 priority patent/WO2004024700A1/en
Priority to MXPA05002644A priority patent/MXPA05002644A/en
Priority to US10/527,391 priority patent/US7687510B2/en
Priority to PL03375647A priority patent/PL375647A1/en
Priority to BR0314186-1A priority patent/BR0314186A/en
Priority to CA2498051A priority patent/CA2498051C/en
Priority to ES03773613T priority patent/ES2414865T3/en
Priority to AU2003282006A priority patent/AU2003282006C1/en
Priority to JP2004571738A priority patent/JP4708034B2/en
Priority to KR1020057004110A priority patent/KR20050042190A/en
Priority to EP03773613.9A priority patent/EP1546113B1/en
Priority to NZ538670A priority patent/NZ538670A/en
Priority to UAA200503292A priority patent/UA82074C2/en
Priority to UY27965A priority patent/UY27965A1/en
Priority to PE2003000910A priority patent/PE20041078A1/en
Priority to TW092124801A priority patent/TWI314555B/en
Publication of GB2392910A publication Critical patent/GB2392910A/en
Priority to MA28139A priority patent/MA27431A1/en
Priority to EC2005005669A priority patent/ECSP055669A/en
Priority to NO20051726A priority patent/NO20051726L/en
Priority to HR20050318A priority patent/HRP20050318A2/en
Priority to HK06108489.5A priority patent/HK1088304A1/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/20—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D239/22—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
GB0315870A 2002-09-10 2003-07-07 2-Oxopyrimidine derivatives and their use as human leukocyte elastase inhibitors Withdrawn GB2392910A (en)

Priority Applications (23)

Application Number Priority Date Filing Date Title
GB0315870A GB2392910A (en) 2002-09-10 2003-07-07 2-Oxopyrimidine derivatives and their use as human leukocyte elastase inhibitors
ARP030103093A AR042179A1 (en) 2002-09-10 2003-08-27 DERIVATIVES OF PIRIMIDIN-2 ONA, PROCEDURE TO SYNTHEIZE THEM, A COMPOSITION, A PROCEDURE FOR THE PREPARATION OF COMPOSITION AND THE USE OF SUCH COMPOUNDS FOR MEDICINES
UAA200503292A UA82074C2 (en) 2002-09-10 2003-08-28 Pyrimidinone derivatives as therapeutic agents against acute and chronic inflammatory, ischaemic and remodelling processes
MXPA05002644A MXPA05002644A (en) 2002-09-10 2003-08-28 Pyrimidinone derivatives as therapeutic agents against acute and chronic inflammatory, ischaemic and remodelling processes.
KR1020057004110A KR20050042190A (en) 2002-09-10 2003-08-28 Pyrimidinone derivatives as therapeutic agents against acute and chronic inflammatory, ischaemic and remodelling processes
NZ538670A NZ538670A (en) 2002-09-10 2003-08-28 Pyrimidinone derivatives as therapeutic agents against acute and chronic inflammatory, ischaemic and remodelling processes
US10/527,391 US7687510B2 (en) 2002-09-10 2003-08-28 Pyrimidinone derivatives as therapeutic agents against acute and chronic inflammatory, ischaemic and remodelling processes
PL03375647A PL375647A1 (en) 2002-09-10 2003-08-28 Pyrimidinone derivatives as therapeutic agents against acute and chronic inflammatory, ischaemic and remodelling processes
BR0314186-1A BR0314186A (en) 2002-09-10 2003-08-28 Pyrimidinone derivatives as therapeutic agents against acute, chronic and ischemic and remodeling inflammatory processes
CA2498051A CA2498051C (en) 2002-09-10 2003-08-28 Pyrimidinone derivatives as therapeutic agents against acute and chronic inflammatory, ischaemic and remodelling processes
ES03773613T ES2414865T3 (en) 2002-09-10 2003-08-28 Pyrimidinone derivatives as therapeutic agents against acute and chronic, ischemic and remodeling inflammatory processes
AU2003282006A AU2003282006C1 (en) 2002-09-10 2003-08-28 Pyrimidinone derivatives as therapeutic agents against acute and chronic inflammatory ischaemic and remodelling processes
JP2004571738A JP4708034B2 (en) 2002-09-10 2003-08-28 Pyrimidinone derivatives as therapeutic agents for acute and chronic inflammation, ischemia and remodeling processes
PCT/EP2003/009525 WO2004024700A1 (en) 2002-09-10 2003-08-28 Pyrimidinone derivatives as therapeutic agents against acute and chronic inflammatory, ischaemic and remodelling processes
EP03773613.9A EP1546113B1 (en) 2002-09-10 2003-08-28 Pyrimidinone derivatives as therapeutic agents against acute and chronic inflammatory, ischaemic and remodelling processes
UY27965A UY27965A1 (en) 2002-09-10 2003-09-08 HETEROCYCLIC DERIVATIVES
TW092124801A TWI314555B (en) 2002-09-10 2003-09-09 Heterocyclic derivatives
PE2003000910A PE20041078A1 (en) 2002-09-10 2003-09-09 INHIBITING HETEROCYCLIC DERIVATIVES OF HUMAN LEUKOCYTIC ELASTASE (HLE)
MA28139A MA27431A1 (en) 2002-09-10 2005-03-10 PYRIMIDINONE DERIVATIVES FOR USE AS THERAPEUTIC AGENTS AGAINST ACUTE AND CHRONIC INFLAMMATORY ISCHEMIC AND INFLAMMATORY PROCESSES
EC2005005669A ECSP055669A (en) 2002-09-10 2005-03-10 DERIVATIVES OF PYRIMIDINONE AS THERAPEUTIC AGENTS AGAINST REMODELING, ISCHEMICAL AND INFLAMMATORY PROCESSES, ACUTE AND CHRONIC
NO20051726A NO20051726L (en) 2002-09-10 2005-04-07 Pyrimidinone derivatives as therapeutic agents for acute and chronic inflammatory, ischemic and remodeling processes
HR20050318A HRP20050318A2 (en) 2002-09-10 2005-04-07 Pyrimidinone derivatives as therapeutic agents against acute and chronic inflamatory, ischaemic and remodelling processes
HK06108489.5A HK1088304A1 (en) 2002-09-10 2006-07-31 Pyrimidinone derivatives as therapeutic agents against acute and chronic inflammatory, ischaemic and remodelling processes

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB0220962A GB0220962D0 (en) 2002-09-10 2002-09-10 Heterocyclic derivatives
GB0315870A GB2392910A (en) 2002-09-10 2003-07-07 2-Oxopyrimidine derivatives and their use as human leukocyte elastase inhibitors

Publications (2)

Publication Number Publication Date
GB0315870D0 true GB0315870D0 (en) 2003-08-13
GB2392910A GB2392910A (en) 2004-03-17

Family

ID=39827677

Family Applications (1)

Application Number Title Priority Date Filing Date
GB0315870A Withdrawn GB2392910A (en) 2002-09-10 2003-07-07 2-Oxopyrimidine derivatives and their use as human leukocyte elastase inhibitors

Country Status (9)

Country Link
JP (1) JP4708034B2 (en)
AR (1) AR042179A1 (en)
EC (1) ECSP055669A (en)
ES (1) ES2414865T3 (en)
GB (1) GB2392910A (en)
HK (1) HK1088304A1 (en)
PE (1) PE20041078A1 (en)
TW (1) TWI314555B (en)
UA (1) UA82074C2 (en)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MXPA03008714A (en) 2002-09-26 2004-09-10 Oreal Sequenced polymers and cosmetic compositions comprising the same.
EP1545440B1 (en) 2002-09-26 2010-11-17 L'Oréal Cosmetic composition comprising a sequenced polymer and a plasticizer
SE0302486D0 (en) 2003-09-18 2003-09-18 Astrazeneca Ab Novel compounds
FR2860143B1 (en) 2003-09-26 2008-06-27 Oreal COSMETIC COMPOSITION COMPRISING A SEQUENCE POLYMER AND A NON-VOLATILE SILICONE OIL
JP4825194B2 (en) * 2004-02-26 2011-11-30 バイエル・シェーリング・ファルマ・アクチェンゲゼルシャフト 1,4-Diaryl-dihydropyrimidin-2-one compounds and their use as human neutrophil elastase inhibitors
JP4825195B2 (en) * 2004-02-26 2011-11-30 バイエル・シェーリング・ファルマ・アクチェンゲゼルシャフト 1,4-Diaryl-dihydropyrimidin-2-one compounds and their use as human neutrophil elastase inhibitors
TW200808771A (en) 2006-05-08 2008-02-16 Astrazeneca Ab Novel compounds II
TW200808763A (en) 2006-05-08 2008-02-16 Astrazeneca Ab Novel compounds I
FR2904320B1 (en) 2006-07-27 2008-09-05 Oreal POLYMER SEQUENCES, AND PROCESS FOR THEIR PREPARATION
US20110003858A1 (en) * 2006-09-04 2011-01-06 Bergstroem Lena Multimeric heterocyclic compounds useful as neutrophil elastase inhibitors
AR069206A1 (en) 2007-11-06 2010-01-06 Astrazeneca Ab DERIVATIVES OF 2-PIRAZINONA, PROCESS TO PREPARE THEM, PHARMACEUTICAL COMPOSITIONS THAT INCLUDE THEM, PREPARATION PROCESS OF THE SAME AND USES IN THE TREATMENT OF OSTEOARTICULAR DISORDERS AND THE RESPIRATORY DEVICE, AMONG OTHERS.
DE102008022521A1 (en) * 2008-05-07 2009-11-12 Bayer Schering Pharma Aktiengesellschaft 1,4-Diaryl-pyrimidopyridazine-2,5-diones and their use
CN101903356B (en) * 2007-12-20 2013-05-22 拜耳知识产权有限责任公司 4-(4-cyano-2-thioaryl)dihydropyrimidinones and use thereof
US8642595B2 (en) * 2008-06-09 2014-02-04 Bayer Intellectual Property Gmbh Annellated 4-(indazolyl)-1,4-dihydropyridine derivatives and methods of use thereof
TW201036957A (en) 2009-02-20 2010-10-16 Astrazeneca Ab Novel salt 628
DE102009016553A1 (en) * 2009-04-06 2010-10-07 Bayer Schering Pharma Aktiengesellschaft Sulfonamide- and sulfoximine-substituted diaryldihydropyrimidinones and their use
MX2012003644A (en) 2009-10-02 2012-04-30 Astrazeneca Ab 2-pyridone compounds used as inhibitors of neutrophil elastase.
US20140221335A1 (en) 2013-02-06 2014-08-07 Boehringer Ingelheim International Gmbh Substituted bicyclic dihydropyrimidinones and their use as inhibitors of neutrophil elastase activity
US9115093B2 (en) 2013-03-04 2015-08-25 Boehringer Ingelheim International Gmbh Substituted bicyclic dihydropyrimidinones and their use as inhibitors of neutrophil elastase activity
USRE47493E1 (en) 2014-02-20 2019-07-09 Boehringer Ingelheim International Gmbh Substituted bicyclic dihydropyrimidinones and their use as inhibitors of neutrophil elastase activity
US9475779B2 (en) 2014-07-31 2016-10-25 Boehringer Ingelheim International Gmbh Substituted bicyclic dihydropyrimidinones and their use as inhibitors of neutrophil elastase activity
US9440930B2 (en) 2014-07-31 2016-09-13 Boehringer Ingelheim International Gmbh Substituted bicyclic dihydropyrimidinones and their use as inhibitors of neutrophil elastase activity
US9458113B2 (en) 2014-07-31 2016-10-04 Boehringer Ingelheim International Gmbh Substituted bicyclic dihydropyrimidinones and their use as inhibitors of neutrophil elastase activity
US9290457B2 (en) 2014-07-31 2016-03-22 Boehringer Ingelheim International Gmbh Substituted dihydropyrimidinones and their use as inhibitors of neutrophil elastase activity
US9657015B2 (en) 2014-07-31 2017-05-23 Boehringer Ingelheim International Gmbh Substituted bicyclic dihydropyrimidinones and their use as inhibitors of neutrophil elastase activity

Also Published As

Publication number Publication date
JP4708034B2 (en) 2011-06-22
HK1088304A1 (en) 2006-11-03
TW200410963A (en) 2004-07-01
ES2414865T3 (en) 2013-07-23
PE20041078A1 (en) 2005-02-25
GB2392910A (en) 2004-03-17
AR042179A1 (en) 2005-06-15
TWI314555B (en) 2009-09-11
UA82074C2 (en) 2008-03-11
JP2006507355A (en) 2006-03-02
ECSP055669A (en) 2005-05-30

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Legal Events

Date Code Title Description
WAP Application withdrawn, taken to be withdrawn or refused ** after publication under section 16(1)