HK1081959A1 - Thienopyriminediones and their use in the modulation of autoimmune disease - Google Patents

Thienopyriminediones and their use in the modulation of autoimmune disease

Info

Publication number
HK1081959A1
HK1081959A1 HK06102161A HK06102161A HK1081959A1 HK 1081959 A1 HK1081959 A1 HK 1081959A1 HK 06102161 A HK06102161 A HK 06102161A HK 06102161 A HK06102161 A HK 06102161A HK 1081959 A1 HK1081959 A1 HK 1081959A1
Authority
HK
Hong Kong
Prior art keywords
sup
thienopyriminediones
modulation
autoimmune disease
compounds
Prior art date
Application number
HK06102161A
Other languages
English (en)
Inventor
Simon David Guile
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of HK1081959A1 publication Critical patent/HK1081959A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Transplantation (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
HK06102161A 2003-01-17 2006-02-17 Thienopyriminediones and their use in the modulation of autoimmune disease HK1081959A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE0300119A SE0300119D0 (sv) 2003-01-17 2003-01-17 Novel compounds
PCT/SE2004/000052 WO2004065394A1 (fr) 2003-01-17 2004-01-15 Thienopyrimidinediones et leur utilisation dans la modulation de maladies auto-immunes

Publications (1)

Publication Number Publication Date
HK1081959A1 true HK1081959A1 (en) 2006-05-26

Family

ID=20290154

Family Applications (1)

Application Number Title Priority Date Filing Date
HK06102161A HK1081959A1 (en) 2003-01-17 2006-02-17 Thienopyriminediones and their use in the modulation of autoimmune disease

Country Status (24)

Country Link
US (2) US7384951B2 (fr)
EP (1) EP1587812B1 (fr)
JP (1) JP4519121B2 (fr)
KR (2) KR101107486B1 (fr)
CN (1) CN100334093C (fr)
AT (1) ATE335748T1 (fr)
AU (1) AU2004206012B2 (fr)
BR (1) BRPI0406801B8 (fr)
CA (1) CA2512441C (fr)
DE (1) DE602004001857T2 (fr)
EG (1) EG25613A (fr)
ES (1) ES2270337T3 (fr)
HK (1) HK1081959A1 (fr)
IL (1) IL169370A (fr)
IS (1) IS2376B (fr)
MX (1) MXPA05007496A (fr)
NO (1) NO333702B1 (fr)
NZ (1) NZ541217A (fr)
PL (1) PL214682B1 (fr)
RU (1) RU2331647C2 (fr)
SE (1) SE0300119D0 (fr)
UA (1) UA81788C2 (fr)
WO (1) WO2004065394A1 (fr)
ZA (1) ZA200505364B (fr)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0117583D0 (en) 2001-07-19 2001-09-12 Astrazeneca Ab Novel compounds
GB0118479D0 (en) * 2001-07-28 2001-09-19 Astrazeneca Ab Novel compounds
SE0300120D0 (sv) * 2003-01-17 2003-01-17 Astrazeneca Ab Novel compounds
NZ541218A (en) * 2003-01-17 2008-05-30 Astrazeneca Ab Thienopyrimidinediones and their use in modulation of autoimmune disease
DK1696920T3 (en) 2003-12-19 2015-01-19 Plexxikon Inc RELATIONS AND PROCEDURES FOR THE DEVELOPMENT OF LAW MODULATORS
US7498342B2 (en) 2004-06-17 2009-03-03 Plexxikon, Inc. Compounds modulating c-kit activity
WO2007013896A2 (fr) 2005-05-17 2007-02-01 Plexxikon, Inc. Composes modulant l'activite de c-kit et c-fms et utilisations
DK1893612T3 (da) 2005-06-22 2011-11-21 Plexxikon Inc Pyrrol [2,3-B]pyridin-derivater som proteinkinasehæmmere
WO2008063888A2 (fr) 2006-11-22 2008-05-29 Plexxikon, Inc. Composés modulant l'activité de c-fms et/ou de c-kit et utilisations associées
WO2008079909A1 (fr) 2006-12-21 2008-07-03 Plexxikon, Inc. Composés et méthodes de modulation des kinases, et indications connexes
PE20121126A1 (es) 2006-12-21 2012-08-24 Plexxikon Inc Compuestos pirrolo [2,3-b] piridinas como moduladores de quinasa
AU2007336811A1 (en) 2006-12-21 2008-07-03 Plexxikon, Inc. Compounds and methods for kinase modulation, and indications therefor
GB0713479D0 (en) * 2007-07-11 2007-08-22 Syngenta Participations Ag Substituted aromatic heterocyclic compounds as fungicides
WO2009012283A1 (fr) 2007-07-17 2009-01-22 Plexxikon Inc. Composés et procédés pour la modulation des kinases et leurs indications
WO2010089580A1 (fr) 2009-02-06 2010-08-12 Astrazeneca Ab Utilisation d'un inhibiteur de mct1 de traitement du cancer exprimant mct1 sur mct4
DK2411397T3 (da) * 2009-03-23 2013-08-05 Glenmark Pharmaceuticals Sa Isothiazol-pyrimidindionderivater som modulatorer af TRPA1
PL2411395T3 (pl) * 2009-03-23 2013-10-31 Glenmark Pharmaceuticals Sa Pochodne furopirymidynodionu jako modulatory TRPA1
ES2552386T3 (es) 2009-04-03 2015-11-27 F. Hoffmann-La Roche Ag Composiciones de {3-[5-(4-cloro-fenil)-1H-pirrol[2,3-b]piridin-3-carbonil]-2,4-difluoro-fenil}-amida del ácido propano-1-sulfónico y usos de las mismas
US8329724B2 (en) 2009-08-03 2012-12-11 Hoffmann-La Roche Inc. Process for the manufacture of pharmaceutically active compounds
JP2013510166A (ja) 2009-11-06 2013-03-21 プレキシコン インコーポレーテッド キナーゼ調節のための化合物、方法およびその適用
AU2012214762B2 (en) 2011-02-07 2015-08-13 Plexxikon Inc. Compounds and methods for kinase modulation, and indications therefor
TWI558702B (zh) 2011-02-21 2016-11-21 普雷辛肯公司 醫藥活性物質的固態形式
EP2804852A2 (fr) 2012-01-20 2014-11-26 Regents Of The University Of Minnesota Composés thérapeutiques
WO2013112881A1 (fr) 2012-01-27 2013-08-01 Thomas Jefferson University Procédés pronostique et thérapeutique liés à l'inhibiteur de la protéine mct
US9150570B2 (en) 2012-05-31 2015-10-06 Plexxikon Inc. Synthesis of heterocyclic compounds
EP2986290A4 (fr) 2013-04-19 2017-01-04 Thomas Jefferson University Methodes associees a la caveoline-1 pour le traitement d'un glioblastome par temozolomide
KR102228034B1 (ko) * 2013-10-21 2021-03-16 제노스코 치환된 피리미딘 화합물 및 syk 억제제로서의 이의 용도
WO2016118825A1 (fr) * 2015-01-22 2016-07-28 The Scripps Research Institute Inhibiteurs hétérocycliques de transporteurs de monocarboxylate
UY36586A (es) * 2015-03-26 2016-10-31 Bayer Pharma AG Heterociclilmetiltienouracilos y uso de los mismos
KR101712836B1 (ko) * 2016-03-17 2017-03-22 주식회사 골프존 가상 골프 시뮬레이션 장치, 가상 골프를 위한 영상 구현 방법 및 이를 기록한 컴퓨팅 장치에 의해 판독 가능한 기록 매체
KR101712838B1 (ko) * 2016-03-17 2017-03-07 주식회사 골프존 가상 골프 시뮬레이션 장치, 가상 골프를 위한 영상 구현 방법 및 이를 기록한 컴퓨팅 장치에 의해 판독 가능한 기록 매체
KR101730536B1 (ko) * 2016-03-17 2017-05-02 주식회사 골프존 스크린 골프 시스템에서 구현되는 컨텐츠 전송 서비스 방법, 컨텐츠 전송 서비스를 위한 모바일 단말기의 제어방법 및 이를 기록한 컴퓨팅 장치에 의해 판독 가능한 기록매체
TWI823932B (zh) 2018-05-11 2023-12-01 中國大陸商迪哲（江蘇）醫藥有限公司 三唑并嘧啶化合物及其在治療癌症中之用途

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US738495A (en) * 1902-12-26 1903-09-08 William E Sherwood Thill-coupling.
SE9702001D0 (sv) * 1997-05-28 1997-05-28 Astra Pharma Prod Novel compounds
US6469014B1 (en) * 1997-05-28 2002-10-22 Astrazeneca Ab Thieno[2,3-d] pyrimidinediones, their preparation and use in therapy
EP1036076B1 (fr) 1997-12-05 2002-09-04 AstraZeneca UK Limited Nouveaux composes
US6232320B1 (en) 1998-06-04 2001-05-15 Abbott Laboratories Cell adhesion-inhibiting antiinflammatory compounds
DE69912618T2 (de) * 1998-08-28 2004-10-28 Astrazeneca Ab NEUE THIENO[2,3-d]PYRIMIDINDIONE, VERFAHREN FÜR IHRE HERSTELLUNG UND IHRE VERWENDUNG IN DER THERAPIE
AU2001252825A1 (en) * 2000-05-04 2001-11-12 Astrazeneca Ab Thieno(2,3-d)pyrimidinediones and their use as pharmaceuticals
GB0117583D0 (en) 2001-07-19 2001-09-12 Astrazeneca Ab Novel compounds
GB0118479D0 (en) 2001-07-28 2001-09-19 Astrazeneca Ab Novel compounds
NZ541218A (en) 2003-01-17 2008-05-30 Astrazeneca Ab Thienopyrimidinediones and their use in modulation of autoimmune disease
SE0300120D0 (sv) * 2003-01-17 2003-01-17 Astrazeneca Ab Novel compounds

Also Published As

Publication number Publication date
RU2331647C2 (ru) 2008-08-20
EG25613A (en) 2012-03-22
NZ541217A (en) 2008-05-30
CN1761672A (zh) 2006-04-19
NO20053826D0 (no) 2005-08-15
SE0300119D0 (sv) 2003-01-17
UA81788C2 (uk) 2008-02-11
KR101107486B1 (ko) 2012-01-19
ATE335748T1 (de) 2006-09-15
BRPI0406801B8 (pt) 2021-05-25
BRPI0406801B1 (pt) 2018-04-03
KR20110125256A (ko) 2011-11-18
NO333702B1 (no) 2013-08-26
CA2512441C (fr) 2012-01-03
JP2006516974A (ja) 2006-07-13
CN100334093C (zh) 2007-08-29
WO2004065394A1 (fr) 2004-08-05
JP4519121B2 (ja) 2010-08-04
ES2270337T3 (es) 2007-04-01
IL169370A0 (en) 2007-07-04
KR20050092760A (ko) 2005-09-22
PL214682B1 (pl) 2013-09-30
EP1587812A1 (fr) 2005-10-26
PL378222A1 (pl) 2006-03-20
RU2005121494A (ru) 2006-02-10
BRPI0406801A (pt) 2006-01-17
DE602004001857T2 (de) 2007-05-24
US20060052400A1 (en) 2006-03-09
DE602004001857D1 (de) 2006-09-21
ZA200505364B (en) 2006-09-27
US7384951B2 (en) 2008-06-10
CA2512441A1 (fr) 2004-08-05
EP1587812B1 (fr) 2006-08-09
IL169370A (en) 2011-05-31
AU2004206012A1 (en) 2004-08-05
IS2376B (is) 2008-07-15
MXPA05007496A (es) 2005-09-21
AU2004206012B2 (en) 2007-06-14
US20080214579A1 (en) 2008-09-04
NO20053826L (no) 2005-10-17
IS7965A (is) 2005-07-29

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Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20210111