HK1078796A1 - 1H-1,2,4-triazole-3-carboxamide derivatives as cannabinoid-cb1- receptor ligands - Google Patents
1H-1,2,4-triazole-3-carboxamide derivatives as cannabinoid-cb1- receptor ligandsInfo
- Publication number
- HK1078796A1 HK1078796A1 HK05110963A HK05110963A HK1078796A1 HK 1078796 A1 HK1078796 A1 HK 1078796A1 HK 05110963 A HK05110963 A HK 05110963A HK 05110963 A HK05110963 A HK 05110963A HK 1078796 A1 HK1078796 A1 HK 1078796A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- cannabinoid
- triazole
- receptor ligands
- carboxamide derivatives
- carboxamide
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4196—1,2,4-Triazoles
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
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- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
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- A—HUMAN NECESSITIES
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- A61P25/08—Antiepileptics; Anticonvulsants
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- A—HUMAN NECESSITIES
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- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
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- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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- A—HUMAN NECESSITIES
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- A61P3/00—Drugs for disorders of the metabolism
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
- C07D249/10—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Diabetes (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Epidemiology (AREA)
- Psychiatry (AREA)
- Hematology (AREA)
- Pain & Pain Management (AREA)
- Obesity (AREA)
- Psychology (AREA)
- Hospice & Palliative Care (AREA)
- Ophthalmology & Optometry (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Addiction (AREA)
- Endocrinology (AREA)
- Emergency Medicine (AREA)
- Child & Adolescent Psychology (AREA)
- Otolaryngology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP02078966 | 2002-09-19 | ||
PCT/EP2003/050628 WO2004026301A1 (fr) | 2002-09-19 | 2003-09-17 | Derives de 1h-1,2,4-triazole-3-carboxamide ayant une activite agoniste partielle, agoniste ou antagoniste inverse du recepteur de cannabinoides-cb1 |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1078796A1 true HK1078796A1 (en) | 2006-03-24 |
Family
ID=31970417
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK05110963A HK1078796A1 (en) | 2002-09-19 | 2005-12-01 | 1H-1,2,4-triazole-3-carboxamide derivatives as cannabinoid-cb1- receptor ligands |
Country Status (25)
Country | Link |
---|---|
US (1) | US7319110B2 (fr) |
EP (1) | EP1542678B1 (fr) |
JP (1) | JP2006501275A (fr) |
KR (1) | KR100996828B1 (fr) |
CN (1) | CN1319529C (fr) |
AR (1) | AR041268A1 (fr) |
AT (1) | ATE458479T1 (fr) |
AU (1) | AU2003299024B2 (fr) |
BR (1) | BR0312020A (fr) |
CA (1) | CA2491394C (fr) |
DE (1) | DE60331444D1 (fr) |
DK (1) | DK1542678T3 (fr) |
ES (1) | ES2341540T3 (fr) |
HK (1) | HK1078796A1 (fr) |
HR (1) | HRP20050053A2 (fr) |
IL (1) | IL165611A (fr) |
MX (1) | MXPA05002862A (fr) |
NO (1) | NO20051870L (fr) |
PL (1) | PL375020A1 (fr) |
PT (1) | PT1542678E (fr) |
RU (1) | RU2325382C2 (fr) |
SI (1) | SI1542678T1 (fr) |
UA (1) | UA80298C2 (fr) |
WO (1) | WO2004026301A1 (fr) |
ZA (1) | ZA200500133B (fr) |
Families Citing this family (51)
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US6897240B2 (en) * | 2002-05-08 | 2005-05-24 | The Regents Of The University Of California | Thio semicarbazone and semicarbazone inhibitors of cysteine proteases and methods of their use |
RU2005135927A (ru) * | 2003-04-21 | 2006-05-10 | Дайити Фармасьютикал Ко., Лтд. (JP) | Пятичленное гетероциклическое производное |
US7223780B2 (en) * | 2003-05-19 | 2007-05-29 | Sanofi-Aventis Deutschland Gmbh | Triazole-derivatives as blood clotting enzyme factor Xa inhibitors |
AU2004283056A1 (en) * | 2003-10-24 | 2005-05-06 | Solvay Pharmaceuticals Gmbh | Novel medical uses of compounds showing CB1-antagonistic activity and combination treatment involving said compounds |
CN1882327A (zh) * | 2003-11-19 | 2006-12-20 | 症变治疗公司 | 含磷的新的拟甲状腺素药 |
US20060025448A1 (en) | 2004-07-22 | 2006-02-02 | Cadila Healthcare Limited | Hair growth stimulators |
FR2874012B1 (fr) * | 2004-08-09 | 2008-08-22 | Sanofi Synthelabo | Derives de pyrrole, leur preparation et leur utlisation en therapeutique |
ES2255834B1 (es) * | 2004-09-14 | 2008-01-16 | Laboratorios Del Dr. Esteve, S.A. | Nuevos derivados 1,2,4-triazol-3-carboxamida. |
CN101031540B (zh) * | 2004-10-01 | 2010-05-26 | 霍夫曼-拉罗奇有限公司 | 六氟异丙醇取代的醚衍生物 |
RU2007119315A (ru) | 2004-10-25 | 2008-11-27 | Зольвай Фармасьютиклз Гмбх (De) | Фармацевтические композиции, содержащие антагонисты каннабиноидного рецептора св1 и открыватели калиевых каналов, предназначенные для лечения сахарного диабета типа i, ожирения и связанных с ними состояний |
WO2006050472A2 (fr) * | 2004-11-03 | 2006-05-11 | Xenoport, Inc. | Prodrogues d'acyloxyalkyl carbamate, et leurs procedes de synthese et d'utilisation |
CA2600052A1 (fr) * | 2005-04-29 | 2006-11-09 | Janssen Pharmaceutica N.V. | Derives de benzotriazole tenant lieu d'antagonistes du recepteur cannabinoide |
US7923465B2 (en) | 2005-06-02 | 2011-04-12 | Glenmark Pharmaceuticals S.A. | Cannabinoid receptor ligands, pharmaceutical compositions containing them, and process for their preparation |
WO2006129178A1 (fr) | 2005-06-02 | 2006-12-07 | Glenmark Pharmaceuticals S.A. | Nouveaux ligands des recepteurs des cannabinoides, compositions pharmaceutiques contenant ces ligands, et procede servant a leur preparation |
TW200726765A (en) | 2005-06-17 | 2007-07-16 | Bristol Myers Squibb Co | Triazolopyridine cannabinoid receptor 1 antagonists |
US7632837B2 (en) | 2005-06-17 | 2009-12-15 | Bristol-Myers Squibb Company | Bicyclic heterocycles as cannabinoid-1 receptor modulators |
EP1910328A1 (fr) * | 2005-06-29 | 2008-04-16 | AstraZeneca AB | Derives de thiophene-2-carboxamide utilises comme modulateurs du recepteur nicotinique alpha7. |
WO2007003962A2 (fr) | 2005-06-30 | 2007-01-11 | Prosidion Limited | Agonistes de gpcr |
FR2894579B1 (fr) * | 2005-12-12 | 2008-01-18 | Sanofi Aventis Sa | Derives diaryltriazolmethylamine, leur preparation et leur application en therapeutique. |
WO2008014199A2 (fr) | 2006-07-28 | 2008-01-31 | Boehringer Ingelheim International Gmbh | Composés modulant le récepteur cb2 |
WO2008033572A1 (fr) * | 2006-09-15 | 2008-03-20 | Xenoport, Inc. | Promédicaments à base de carbamate d'acyloxyalkyle, procédés de synthèse et utilisation |
JP2010514832A (ja) | 2007-01-04 | 2010-05-06 | プロシディオン・リミテッド | ピペリジンgpcrアゴニスト |
CL2008000017A1 (es) | 2007-01-04 | 2008-08-01 | Prosidion Ltd | Compuestos derivados de heterociclos de nitrogeno y oxigeno, agonistas de gpcr; composicion farmaceutica que comprende a dicho compuesto; y uso del compuesto para el tratamiento de la obesidad, diabetes, sindrome metabolico, hiperlipidemia, toleranci |
RS52065B (en) | 2007-01-04 | 2012-06-30 | Prosidion Ltd | PIPERIDINSKI GPCR AGONIST |
AR064735A1 (es) | 2007-01-04 | 2009-04-22 | Prosidion Ltd | Agonistas de gpcr y composicion farmaceutica en base al compuesto |
GB0700122D0 (en) | 2007-01-04 | 2007-02-14 | Prosidion Ltd | GPCR agonists |
CN101302200B (zh) * | 2007-05-09 | 2011-04-20 | 上海医药工业研究院 | 制备n-哌啶子基-5-(4-氯苯基)-1-(2,4-二氯苯基)-4-甲基吡唑-3-甲酰胺的方法 |
GB0720389D0 (en) | 2007-10-18 | 2008-11-12 | Prosidion Ltd | G-Protein Coupled Receptor Agonists |
GB0720390D0 (en) | 2007-10-18 | 2007-11-28 | Prosidion Ltd | G-Protein coupled receptor agonists |
CA2704684A1 (fr) | 2007-11-07 | 2009-05-14 | Boehringer Ingelheim International Gmbh | Composes modulant le recepteur cb2 |
WO2009105509A1 (fr) | 2008-02-21 | 2009-08-27 | Boehringer Ingelheim International Gmbh | Composés amine et éther qui modulent le récepteur cb2 |
JP5749162B2 (ja) | 2008-07-10 | 2015-07-15 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | Cb2受容体を調節するスルホン化合物 |
EP2342200B1 (fr) | 2008-09-25 | 2013-01-23 | Boehringer Ingelheim International GmbH | Composés modulant sélectivement le récepteur cb2 |
US8629157B2 (en) | 2009-01-05 | 2014-01-14 | Boehringer Ingelheim International Gmbh | Pyrrolidine compounds which modulate the CB2 receptor |
WO2010079241A1 (fr) | 2009-01-12 | 2010-07-15 | Fundacion Hospital Nacional De Paraplejicos Para La Investigacion Y La Integracion | Utilisation d'antagonistes et/ou d'agonistes inverses des récepteurs cb1 pour la préparation de médicaments qui augmentent l'excitabilité des motoneurones |
WO2010096371A2 (fr) | 2009-02-18 | 2010-08-26 | Boehringer Ingelheim International Gmbh | Composés hétérocycliques qui modulent le récepteur cb2 |
US8299103B2 (en) | 2009-06-15 | 2012-10-30 | Boehringer Ingelheim International Gmbh | Compounds which selectively modulate the CB2 receptor |
EP2443107B1 (fr) | 2009-06-16 | 2018-08-08 | Boehringer Ingelheim International GmbH | Dérivés d'azétidine 2-carboxamide qui modulent le récepteur cb2 |
US8383651B2 (en) | 2009-09-22 | 2013-02-26 | Boehringer Ingelheim International Gmbh | Compounds which selectively modulate the CB2 receptor |
EP2523936A1 (fr) | 2010-01-15 | 2012-11-21 | Boehringer Ingelheim International GmbH | Composés qui modulent le récepteur cb2 |
EP2542539B1 (fr) | 2010-03-05 | 2014-02-26 | Boehringer Ingelheim International GmbH | Composés tétrazoles qui modulent sélectivement le récepteur cb2 |
JP5746764B2 (ja) | 2010-07-22 | 2015-07-08 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | Cb2受容体を調節する化合物 |
CN102558157B (zh) * | 2010-12-20 | 2014-04-30 | 中国科学院上海药物研究所 | 羟乙基三唑类化合物或氨乙基三唑类化合物及其制备方法和用途 |
CN102731418B (zh) * | 2012-07-15 | 2015-03-11 | 浙江大学 | 1-取代-1h-1,2,4-三氮唑-甲酰胺衍生物及其制备和用途 |
ES2605632T3 (es) * | 2012-09-17 | 2017-03-15 | F. Hoffmann-La Roche Ag | Derivados triazol carboxamida |
EP2803668A1 (fr) | 2013-05-17 | 2014-11-19 | Boehringer Ingelheim International Gmbh | Nouveau (cyano-dimethyl-methyl)-isoxazoles et - [1,3,4] thiadiazoles |
BR112016028119A2 (pt) | 2014-06-06 | 2017-08-22 | Res Triangle Inst | Agonistas receptores de apelina (apj) e usos dos mesmos |
CN107406420B (zh) | 2015-01-30 | 2020-11-06 | 纽罗克里生物科学有限公司 | 取代的三唑及与其相关的方法 |
EP3386976A1 (fr) | 2015-12-09 | 2018-10-17 | Research Triangle Institute, International | Agonistes améliorés du récepteur de l'apéline (apj) et leurs utilisations |
JP7104690B2 (ja) * | 2016-10-12 | 2022-07-21 | リサーチ トライアングル インスティテュート | 複素環式アペリン受容体(apj)アゴニスト及びそれらの使用 |
WO2020103856A1 (fr) * | 2018-11-20 | 2020-05-28 | Shanghaitech University | Inhibiteurs de mmpl3, compositions et utilisations associées |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
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JPS58194866A (ja) * | 1982-05-07 | 1983-11-12 | Kureha Chem Ind Co Ltd | トリアゾ−ル誘導体及び該誘導体を含有する除草剤 |
DE3316300A1 (de) * | 1982-05-07 | 1983-11-24 | Kureha Kagaku Kogyo K.K., Tokyo | Heribizide zusammensetzung mit einem gehalt an einem derivat des 1,2,4-triazols als wirkstoff |
DE3817192A1 (de) * | 1988-05-20 | 1989-11-30 | Hoechst Ag | 1,2,4-triazolderivate enthaltende pflanzenschuetzende mittel sowie neue derivate des 1,2,4-triazols |
FR2692575B1 (fr) * | 1992-06-23 | 1995-06-30 | Sanofi Elf | Nouveaux derives du pyrazole, procede pour leur preparation et compositions pharmaceutiques les contenant. |
DE4225778A1 (de) * | 1992-08-04 | 1994-02-17 | Hoechst Ag | 1,2,4-Triazolyl-3-carbonsäure-4-aminopiperidide, Verfahren zu ihrer Herstellung, sie enthaltende Mittel und ihre Verwendung als Schädlingsbekämpfungsmittel, insbesondere Fungizide |
FR2741621B1 (fr) * | 1995-11-23 | 1998-02-13 | Sanofi Sa | Nouveaux derives de pyrazole, procede pour leur preparation et compositions pharmaceutiques en contenant |
FR2789079B3 (fr) * | 1999-02-01 | 2001-03-02 | Sanofi Synthelabo | Derive d'acide pyrazolecarboxylique, sa preparation, les compositions pharmaceutiques en contenant |
EP1224173B1 (fr) | 1999-10-18 | 2005-10-12 | The University Of Connecticut | Derives de pyrazole comme antagonistes des recepteurs des cannabinoides |
CA2399791A1 (fr) | 2000-02-11 | 2001-08-16 | Bristol-Myers Squibb Company | Modulateurs de recepteurs aux cannabinoides, leurs procedes de preparation et utilisations de modulateurs de recepteurs aux cannabinoides pour le traitement de maladies respiratoires et non respiratoires |
-
2003
- 2003-09-16 AR ARP030103347A patent/AR041268A1/es unknown
- 2003-09-16 US US10/662,477 patent/US7319110B2/en not_active Expired - Fee Related
- 2003-09-17 KR KR1020057004584A patent/KR100996828B1/ko not_active IP Right Cessation
- 2003-09-17 CN CNB038173522A patent/CN1319529C/zh not_active Expired - Fee Related
- 2003-09-17 PL PL03375020A patent/PL375020A1/xx not_active Application Discontinuation
- 2003-09-17 CA CA2491394A patent/CA2491394C/fr not_active Expired - Fee Related
- 2003-09-17 RU RU2005103244/04A patent/RU2325382C2/ru not_active IP Right Cessation
- 2003-09-17 BR BR0312020-1A patent/BR0312020A/pt not_active IP Right Cessation
- 2003-09-17 MX MXPA05002862A patent/MXPA05002862A/es active IP Right Grant
- 2003-09-17 SI SI200331803T patent/SI1542678T1/sl unknown
- 2003-09-17 UA UAA200503704A patent/UA80298C2/uk unknown
- 2003-09-17 DE DE60331444T patent/DE60331444D1/de not_active Expired - Lifetime
- 2003-09-17 EP EP03797318A patent/EP1542678B1/fr not_active Expired - Lifetime
- 2003-09-17 ES ES03797318T patent/ES2341540T3/es not_active Expired - Lifetime
- 2003-09-17 WO PCT/EP2003/050628 patent/WO2004026301A1/fr active Application Filing
- 2003-09-17 AT AT03797318T patent/ATE458479T1/de active
- 2003-09-17 PT PT03797318T patent/PT1542678E/pt unknown
- 2003-09-17 AU AU2003299024A patent/AU2003299024B2/en not_active Ceased
- 2003-09-17 JP JP2004537155A patent/JP2006501275A/ja active Pending
- 2003-09-17 DK DK03797318.7T patent/DK1542678T3/da active
-
2004
- 2004-12-07 IL IL165611A patent/IL165611A/en not_active IP Right Cessation
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2005
- 2005-01-06 ZA ZA200500133A patent/ZA200500133B/en unknown
- 2005-01-19 HR HR20050053A patent/HRP20050053A2/xx not_active Application Discontinuation
- 2005-04-18 NO NO20051870A patent/NO20051870L/no not_active Application Discontinuation
- 2005-12-01 HK HK05110963A patent/HK1078796A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
DE60331444D1 (de) | 2010-04-08 |
WO2004026301A1 (fr) | 2004-04-01 |
RU2005103244A (ru) | 2005-06-27 |
BR0312020A (pt) | 2005-03-22 |
UA80298C2 (en) | 2007-09-10 |
CN1671377A (zh) | 2005-09-21 |
PL375020A1 (en) | 2005-11-14 |
SI1542678T1 (sl) | 2010-07-30 |
ES2341540T3 (es) | 2010-06-22 |
AU2003299024B2 (en) | 2008-03-06 |
AR041268A1 (es) | 2005-05-11 |
NO20051870L (no) | 2005-06-03 |
KR100996828B1 (ko) | 2010-11-29 |
DK1542678T3 (da) | 2010-06-07 |
CA2491394C (fr) | 2010-06-15 |
CN1319529C (zh) | 2007-06-06 |
US20040106614A1 (en) | 2004-06-03 |
IL165611A0 (en) | 2006-01-15 |
HRP20050053A2 (en) | 2005-04-30 |
US7319110B2 (en) | 2008-01-15 |
EP1542678B1 (fr) | 2010-02-24 |
IL165611A (en) | 2010-04-15 |
ZA200500133B (en) | 2005-11-01 |
ATE458479T1 (de) | 2010-03-15 |
CA2491394A1 (fr) | 2004-04-01 |
MXPA05002862A (es) | 2005-05-27 |
KR20050057399A (ko) | 2005-06-16 |
EP1542678A1 (fr) | 2005-06-22 |
RU2325382C2 (ru) | 2008-05-27 |
AU2003299024A1 (en) | 2004-04-08 |
PT1542678E (pt) | 2010-05-25 |
JP2006501275A (ja) | 2006-01-12 |
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PC | Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee) |
Effective date: 20110917 |