HK1070921A1 - Method for determining the expression level of glutathione-s-transferase pi - Google Patents

Method for determining the expression level of glutathione-s-transferase pi

Info

Publication number
HK1070921A1
HK1070921A1 HK05103515.5A HK05103515A HK1070921A1 HK 1070921 A1 HK1070921 A1 HK 1070921A1 HK 05103515 A HK05103515 A HK 05103515A HK 1070921 A1 HK1070921 A1 HK 1070921A1
Authority
HK
Hong Kong
Prior art keywords
gst
expression level
mrna
patient
glutathione
Prior art date
Application number
HK05103515.5A
Other languages
English (en)
Inventor
Kathleen D Danenberg
Original Assignee
Response Genetics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Response Genetics Inc filed Critical Response Genetics Inc
Publication of HK1070921A1 publication Critical patent/HK1070921A1/xx

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1085—Transferases (2.) transferring alkyl or aryl groups other than methyl groups (2.5)
    • C12N9/1088—Glutathione transferase (2.5.1.18)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/243—Platinum; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6806—Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y205/00—Transferases transferring alkyl or aryl groups, other than methyl groups (2.5)
    • C12Y205/01—Transferases transferring alkyl or aryl groups, other than methyl groups (2.5) transferring alkyl or aryl groups, other than methyl groups (2.5.1)
    • C12Y205/01018—Glutathione transferase (2.5.1.18)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pathology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Hospice & Palliative Care (AREA)
  • Oncology (AREA)
  • Inorganic Chemistry (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
HK05103515.5A 2001-06-14 2005-04-25 Method for determining the expression level of glutathione-s-transferase pi HK1070921A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/879,986 US6686155B2 (en) 2001-06-14 2001-06-14 Method of determining a chemotherapeutic regimen based on glutathione-S-transferase pi expression
PCT/US2002/015203 WO2002103055A1 (fr) 2001-06-14 2002-05-15 Procede permettant de determiner un schema de chimiotherapie base sur l'expression d'une glutathione-s-transferase pi

Publications (1)

Publication Number Publication Date
HK1070921A1 true HK1070921A1 (en) 2005-06-30

Family

ID=25375288

Family Applications (1)

Application Number Title Priority Date Filing Date
HK05103515.5A HK1070921A1 (en) 2001-06-14 2005-04-25 Method for determining the expression level of glutathione-s-transferase pi

Country Status (15)

Country Link
US (4) US6686155B2 (fr)
EP (1) EP1407047B1 (fr)
JP (2) JP4303104B2 (fr)
KR (2) KR20090060380A (fr)
CN (2) CN100494398C (fr)
AR (1) AR034342A1 (fr)
AU (1) AU2002305573B2 (fr)
CA (1) CA2450257C (fr)
ES (1) ES2457077T3 (fr)
HK (1) HK1070921A1 (fr)
IL (2) IL159301A0 (fr)
MX (1) MXPA03011632A (fr)
NZ (1) NZ530520A (fr)
TW (1) TWI338049B (fr)
WO (1) WO2002103055A1 (fr)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
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US20040204435A1 (en) * 2003-04-09 2004-10-14 Joachim Liehr Alternating treatment with topoisomerase I and topoisomerase II inhibitors
WO2005100606A2 (fr) * 2004-04-09 2005-10-27 Genomic Health, Inc. Marqueurs d'expression genique permettant de predire la reponse a la chimiotherapie
US20060115827A1 (en) * 2004-07-01 2006-06-01 University Of Southern California Genetic markers for predicting disease and treatment outcome
WO2006119464A1 (fr) * 2005-05-04 2006-11-09 University Of South Florida Prediction de reponse de traitement chez des sujets cancereux
US20070059753A1 (en) * 2005-09-15 2007-03-15 Tatiana Vener Detecting gene methylation
ES2401475T3 (es) * 2007-06-15 2013-04-19 University Of South Florida Métodos de diagnóstico y tratamiento del cáncer
AU2009339802B2 (en) * 2009-02-16 2014-07-24 Atlas Antibodies Ab RBM3 as a marker for malignant melanoma prognosis
JP5361488B2 (ja) * 2009-03-24 2013-12-04 オリンパス株式会社 蛍光観察装置
JP5680442B2 (ja) * 2011-02-24 2015-03-04 シスメックス株式会社 癌細胞のタキサン系抗癌剤感受性判定方法、それを実現するためのコンピュータプログラム及び装置
GB201316027D0 (en) * 2013-09-09 2013-10-23 Almac Diagnostics Ltd Molecular diagnostic test for oesophageal cancer
CN113577290B (zh) * 2014-12-26 2023-10-24 日东电工株式会社 细胞死亡诱导试剂、细胞增殖抑制试剂及用于治疗由细胞增殖异常导致的疾病的医药组合物
CN112321489B (zh) * 2020-10-15 2022-04-19 中山大学 一种基于活性巯基和报告离子的亲电分子探针及其制备方法和应用

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US4830969A (en) * 1981-08-31 1989-05-16 The Research Foundation Of State University Of New York Process for the rapid and simple isolation of nucleic acids
US4843155A (en) * 1987-11-19 1989-06-27 Piotr Chomczynski Product and process for isolating RNA
US5128247A (en) * 1989-08-14 1992-07-07 Board Of Regents, The University Of Texas System Methods for isolation of nucleic acids from eukaryotic and prokaryotic sources
US5942389A (en) * 1990-10-19 1999-08-24 Board Of Trustees Of The University Of Illinois Genes and genetic elements associated with sensitivity to cisplatin
US5204241A (en) * 1990-10-22 1993-04-20 Oxi-Gene Inc. Glutathione-S-transferase mu as a measure of drug resistance
US5620852A (en) * 1990-11-14 1997-04-15 Hri Research, Inc. Nucleic acid preparation methods
US5284940A (en) * 1990-11-14 1994-02-08 Hri Research, Inc. Preparation for nucleic acid samples
US5654179A (en) * 1990-11-14 1997-08-05 Hri Research, Inc. Nucleic acid preparation methods
US5346994A (en) * 1992-01-28 1994-09-13 Piotr Chomczynski Shelf-stable product and process for isolating RNA, DNA and proteins
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JP3615545B2 (ja) * 1993-02-01 2005-02-02 キアゲン・エヌ・ブイ 第四級アンモニウム塩界面活性剤及びそのｒｎａの単離剤
US5637687A (en) * 1993-08-31 1997-06-10 Wiggins; James C. Methods and compositions for isolating nucleic acids
AU2289495A (en) 1994-04-13 1995-11-10 Uab Research Foundation, The Dihydropyrimidine dehydrogenase compositions and methods of use
US5643767A (en) * 1994-05-02 1997-07-01 The Rockefeller University Process for isolating cellular components
CA2153215A1 (fr) * 1994-07-06 1996-01-07 Lu Wang Traitement de tissus enchasses dans la paraffine pour l'analyse genique
US6136605A (en) * 1994-08-26 2000-10-24 Wisconsin Alumni Research Foundation Glutathione S-transferase isoforms
US5707802A (en) * 1995-01-13 1998-01-13 Ciba Corning Diagnostics Corp. Nucleic acid probes for the detection and identification of fungi
US5777099A (en) * 1995-02-24 1998-07-07 Biotecx Laboratories, Inc. RNA separation
US5945515A (en) * 1995-07-31 1999-08-31 Chomczynski; Piotr Product and process for isolating DNA, RNA and proteins
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EP0791654A1 (fr) * 1996-02-21 1997-08-27 Jürgen A. Dr. Richt Polypeptides aux séquences d'acides aminés des protéines p57 ou p9.5 du virus de la maladie Borna, fragments d'acide nucléique codant pour ceux-ci et leur utilisation pour des buts diagnostiques et d'immunisation
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ES2185002T3 (es) 1996-03-20 2003-04-16 Us Gov Health & Human Serv Metodos y composiciones para detectar mutaciones por empalme de la deshidrogenasa de dihidro-pirimidina.
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Also Published As

Publication number Publication date
IL159301A0 (en) 2004-06-01
ES2457077T3 (es) 2014-04-24
MXPA03011632A (es) 2005-04-19
KR20090060380A (ko) 2009-06-11
JP4303104B2 (ja) 2009-07-29
CN1541277A (zh) 2004-10-27
US20020197609A1 (en) 2002-12-26
CN1763064A (zh) 2006-04-26
CA2450257A1 (fr) 2002-12-27
EP1407047A4 (fr) 2005-03-30
CN100494398C (zh) 2009-06-03
AU2002305573B2 (en) 2009-01-08
CN100355770C (zh) 2007-12-19
JP4308309B2 (ja) 2009-08-05
EP1407047A1 (fr) 2004-04-14
US6686155B2 (en) 2004-02-03
US20040241705A1 (en) 2004-12-02
EP1407047B1 (fr) 2014-01-22
TWI338049B (en) 2011-03-01
KR100918927B1 (ko) 2009-09-28
US20050019783A1 (en) 2005-01-27
US20050074775A1 (en) 2005-04-07
KR20040018269A (ko) 2004-03-02
NZ530520A (en) 2006-10-27
JP2004530434A (ja) 2004-10-07
CA2450257C (fr) 2012-11-06
WO2002103055A1 (fr) 2002-12-27
IL159301A (en) 2010-06-16
JP2009000118A (ja) 2009-01-08
US7138507B2 (en) 2006-11-21
AR034342A1 (es) 2004-02-18

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Legal Events

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PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20190515