ES2185002T3 - Metodos y composiciones para detectar mutaciones por empalme de la deshidrogenasa de dihidro-pirimidina. - Google Patents
Metodos y composiciones para detectar mutaciones por empalme de la deshidrogenasa de dihidro-pirimidina.Info
- Publication number
- ES2185002T3 ES2185002T3 ES97915143T ES97915143T ES2185002T3 ES 2185002 T3 ES2185002 T3 ES 2185002T3 ES 97915143 T ES97915143 T ES 97915143T ES 97915143 T ES97915143 T ES 97915143T ES 2185002 T3 ES2185002 T3 ES 2185002T3
- Authority
- ES
- Spain
- Prior art keywords
- methods
- compositions
- empalme
- dihydro
- detect mutations
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
- C12Q1/6837—Enzymatic or biochemical coupling of nucleic acids to a solid phase using probe arrays or probe chips
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Physics & Mathematics (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Analytical Chemistry (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
LA PRESENTE INVENCION PROPORCIONA COMPOSICIONES, METODOS Y KITS PARA LA DETECCION DE POLIMORFISMOS O MUTACIONES GENETICOS RELACIONADOS CON LE DEFICIENCIA DE DIHIDROPIRIMIDINA DEHIDROGENASA (DPDD), EL POLIMORFISMO O MUTACIONES OCURREN GENERALMENTE EN EL GEN DPD DE DIHIDROPIRIMIDINA DEHIDROGENASA EN EL CROMOSOMA 1. TAMBIEN SE PROPORCIONAN FORMAS MUTANTES DE DPD.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US1383596P | 1996-03-20 | 1996-03-20 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2185002T3 true ES2185002T3 (es) | 2003-04-16 |
Family
ID=21762020
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES97915143T Expired - Lifetime ES2185002T3 (es) | 1996-03-20 | 1997-03-19 | Metodos y composiciones para detectar mutaciones por empalme de la deshidrogenasa de dihidro-pirimidina. |
Country Status (8)
Country | Link |
---|---|
EP (1) | EP0896629B8 (es) |
AT (1) | ATE225404T1 (es) |
AU (1) | AU2215897A (es) |
CA (1) | CA2249364C (es) |
DE (1) | DE69716057T2 (es) |
DK (1) | DK0896629T3 (es) |
ES (1) | ES2185002T3 (es) |
WO (1) | WO1997035034A1 (es) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6787306B1 (en) | 1996-03-20 | 2004-09-07 | The United States Of America As Represented By The Department Of Health And Human Services | Methods and compositions for detecting dihydropyrimidine dehydrogenase splicing mutations |
AU771446B2 (en) * | 1996-03-20 | 2004-03-25 | Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The | Methods and compositions for detecting dihydropyrimidine dehydrogenase splicing mutations |
WO2001036686A2 (en) * | 1999-11-15 | 2001-05-25 | University Of Southern California | Genomic polymorphism for predicting therapeutic response |
US20020142328A1 (en) | 2000-12-01 | 2002-10-03 | Danenberg Kathleen D. | Method of determining a chemotherapeutic regimen by assaying gene expression in primary tumors |
US7005278B2 (en) | 2001-03-02 | 2006-02-28 | Danenberg Kathleen D | Method of determining dihydropyrimidine dehydrogenase gene expression |
US7049059B2 (en) | 2000-12-01 | 2006-05-23 | Response Genetics, Inc. | Method of determining a chemotherapeutic regimen based on ERCC1 and TS expression |
US6602670B2 (en) | 2000-12-01 | 2003-08-05 | Response Genetics, Inc. | Method of determining a chemotherapeutic regimen based on ERCC1 expression |
US6956111B2 (en) | 2001-03-02 | 2005-10-18 | Response Genetics, Inc. | Method of determining dihydropyrimidine dehydrogenase gene expression |
US6686155B2 (en) | 2001-06-14 | 2004-02-03 | Response Genetics, Inc. | Method of determining a chemotherapeutic regimen based on glutathione-S-transferase pi expression |
FR2884257B1 (fr) * | 2005-04-12 | 2010-11-26 | Centre Regional De Lutte Contre Le Cancer Dangers | Prevention des toxicites dues au 5-fluorouracile |
US8440398B2 (en) | 2006-01-25 | 2013-05-14 | Taiho Pharmaceutical Co., Ltd. | Method for prediction of sensitivity to 5-fluorouracil-type anticancer agent |
-
1997
- 1997-03-19 AU AU22158/97A patent/AU2215897A/en not_active Abandoned
- 1997-03-19 CA CA002249364A patent/CA2249364C/en not_active Expired - Lifetime
- 1997-03-19 WO PCT/US1997/004269 patent/WO1997035034A1/en active IP Right Grant
- 1997-03-19 EP EP97915143A patent/EP0896629B8/en not_active Expired - Lifetime
- 1997-03-19 AT AT97915143T patent/ATE225404T1/de active
- 1997-03-19 ES ES97915143T patent/ES2185002T3/es not_active Expired - Lifetime
- 1997-03-19 DK DK97915143T patent/DK0896629T3/da active
- 1997-03-19 DE DE69716057T patent/DE69716057T2/de not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
ATE225404T1 (de) | 2002-10-15 |
CA2249364A1 (en) | 1997-09-25 |
EP0896629B1 (en) | 2002-10-02 |
DE69716057D1 (de) | 2002-11-07 |
CA2249364C (en) | 2009-07-07 |
EP0896629B8 (en) | 2003-01-02 |
AU2215897A (en) | 1997-10-10 |
DE69716057T2 (de) | 2003-07-03 |
DK0896629T3 (da) | 2003-02-03 |
EP0896629A1 (en) | 1999-02-17 |
WO1997035034A1 (en) | 1997-09-25 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
Zak et al. | Repair of O6-methylguanine and O4-methylthymine by the human and rat O6-methylguanine-DNA methyltransferases. | |
WO1998030883A3 (en) | Analysis of genetic polymorphisms and gene copy number | |
ES2185002T3 (es) | Metodos y composiciones para detectar mutaciones por empalme de la deshidrogenasa de dihidro-pirimidina. | |
CA2251842A1 (en) | Small molecule mimetics of erythropoietin | |
WO1999052942A3 (en) | Genomic sequence of the 5-lipoxygenase-activating protein (flap), polymorphic markers thereof and methods for detection of asthma | |
WO2001050829A3 (en) | Alzheimer's disease secretase, app substrates therefor, and uses therefor | |
AU2001268449A1 (en) | Toxicity typing using liver stem cells | |
ATE454468T1 (de) | Nachweis der instabilität von mikrosatelliten und verwendung davon bei der tumordiagnose | |
IL146448A0 (en) | Dr4 antibodies and uses thereof | |
WO2000063441A3 (en) | Single nucleotide polymorphisms in mitochondrial genes that segregate with alzheimer's disease | |
AU6659698A (en) | Compositions, methods, kits and apparatus for determining the presence or absence of target molecules | |
DK0760010T3 (da) | Fremgangsmåder til screening for Crohn's sygdom under anvendelse af TNF-mikrosatellit-alleler | |
WO2001096604A3 (en) | Assay for genetic polymorphisms using scattered light detectable labels | |
WO2003087763A3 (en) | Association of polymorphisms in the sost gene region with bone mineral density | |
EP2314715A3 (en) | Method for the amplification of HLA class I alleles | |
ATE277171T1 (de) | Ikk-alpha proteine, nukleinsäuren und verfahren | |
DE69931279D1 (de) | Methode und zusammensetzungen zum vermindern des cholesterolspiegels im plasma | |
WO2000022122A3 (en) | Genes, proteins and biallelic markers related to central nervous system disease | |
WO2005046459A3 (en) | Primers, methods and kits for detecting killer-cell immunoglobulin-like receptor alleles | |
WO1997024974A3 (en) | Compositions and methods for diagnosis of mutation in the von hippel-lindau tumor suppressor gene | |
ATE174634T1 (de) | Verfahren und proben zum nachweis von mit dem locus der infantilen spinalamyotrophien verbundenen markern | |
EP0747489A3 (en) | Nucleic acid probes and amplification oligonucleotides for Neisseria species | |
WO2001023410A3 (en) | Drug target isogenes: polymorphisms in the interleukin 13 gene | |
WO2001027312A3 (en) | Drug target isogenes: polymorphisms in the m1 muscarinic acetylcholine receptor gene | |
WO2003018605A3 (en) | Solid-phase synthesis of oligosaccharides and glycopeptides using glycosynthases |