ATE225404T1 - Verfahren und zusammensetzungen zum nachweis von spleiss-mutationen in dihydropyremudine dehydrogenase - Google Patents
Verfahren und zusammensetzungen zum nachweis von spleiss-mutationen in dihydropyremudine dehydrogenaseInfo
- Publication number
- ATE225404T1 ATE225404T1 AT97915143T AT97915143T ATE225404T1 AT E225404 T1 ATE225404 T1 AT E225404T1 AT 97915143 T AT97915143 T AT 97915143T AT 97915143 T AT97915143 T AT 97915143T AT E225404 T1 ATE225404 T1 AT E225404T1
- Authority
- AT
- Austria
- Prior art keywords
- methods
- compositions
- dihydropyremudine
- dehydrogenase
- splicing mutations
- Prior art date
Links
- 230000035772 mutation Effects 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 title abstract 2
- 101710088194 Dehydrogenase Proteins 0.000 title 1
- 201000010385 Dihydropyrimidine Dehydrogenase Deficiency Diseases 0.000 abstract 2
- 102100022334 Dihydropyrimidine dehydrogenase [NADP(+)] Human genes 0.000 abstract 1
- 108010066455 Dihydrouracil Dehydrogenase (NADP) Proteins 0.000 abstract 1
- 206010071602 Genetic polymorphism Diseases 0.000 abstract 1
- 210000000349 chromosome Anatomy 0.000 abstract 1
- 238000001514 detection method Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
- C12Q1/6837—Enzymatic or biochemical coupling of nucleic acids to a solid phase using probe arrays or probe chips
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Physics & Mathematics (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Analytical Chemistry (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US1383596P | 1996-03-20 | 1996-03-20 | |
| PCT/US1997/004269 WO1997035034A1 (en) | 1996-03-20 | 1997-03-19 | Methods and compositions for detecting dihydropyrimidine dehydrogenase splicing mutations |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE225404T1 true ATE225404T1 (de) | 2002-10-15 |
Family
ID=21762020
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT97915143T ATE225404T1 (de) | 1996-03-20 | 1997-03-19 | Verfahren und zusammensetzungen zum nachweis von spleiss-mutationen in dihydropyremudine dehydrogenase |
Country Status (8)
| Country | Link |
|---|---|
| EP (1) | EP0896629B8 (de) |
| AT (1) | ATE225404T1 (de) |
| AU (1) | AU2215897A (de) |
| CA (1) | CA2249364C (de) |
| DE (1) | DE69716057T2 (de) |
| DK (1) | DK0896629T3 (de) |
| ES (1) | ES2185002T3 (de) |
| WO (1) | WO1997035034A1 (de) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU771446B2 (en) * | 1996-03-20 | 2004-03-25 | Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The | Methods and compositions for detecting dihydropyrimidine dehydrogenase splicing mutations |
| US6787306B1 (en) | 1996-03-20 | 2004-09-07 | The United States Of America As Represented By The Department Of Health And Human Services | Methods and compositions for detecting dihydropyrimidine dehydrogenase splicing mutations |
| JP2003521896A (ja) * | 1999-11-15 | 2003-07-22 | ユニバーシティ・オブ・サザン・カリフォルニア | 治療応答を予測するためのゲノム多形現象 |
| US6602670B2 (en) | 2000-12-01 | 2003-08-05 | Response Genetics, Inc. | Method of determining a chemotherapeutic regimen based on ERCC1 expression |
| US7049059B2 (en) | 2000-12-01 | 2006-05-23 | Response Genetics, Inc. | Method of determining a chemotherapeutic regimen based on ERCC1 and TS expression |
| US20020142328A1 (en) | 2000-12-01 | 2002-10-03 | Danenberg Kathleen D. | Method of determining a chemotherapeutic regimen by assaying gene expression in primary tumors |
| US7005278B2 (en) | 2001-03-02 | 2006-02-28 | Danenberg Kathleen D | Method of determining dihydropyrimidine dehydrogenase gene expression |
| US6956111B2 (en) | 2001-03-02 | 2005-10-18 | Response Genetics, Inc. | Method of determining dihydropyrimidine dehydrogenase gene expression |
| US6686155B2 (en) | 2001-06-14 | 2004-02-03 | Response Genetics, Inc. | Method of determining a chemotherapeutic regimen based on glutathione-S-transferase pi expression |
| FR2884257B1 (fr) * | 2005-04-12 | 2010-11-26 | Centre Regional De Lutte Contre Le Cancer Dangers | Prevention des toxicites dues au 5-fluorouracile |
| WO2007086351A1 (ja) * | 2006-01-25 | 2007-08-02 | Taiho Pharmaceutical Co., Ltd. | ５－フルオロウラシル系抗癌剤に対する感受性を予測する方法 |
-
1997
- 1997-03-19 WO PCT/US1997/004269 patent/WO1997035034A1/en not_active Ceased
- 1997-03-19 CA CA002249364A patent/CA2249364C/en not_active Expired - Lifetime
- 1997-03-19 AT AT97915143T patent/ATE225404T1/de active
- 1997-03-19 AU AU22158/97A patent/AU2215897A/en not_active Abandoned
- 1997-03-19 EP EP97915143A patent/EP0896629B8/de not_active Expired - Lifetime
- 1997-03-19 DK DK97915143T patent/DK0896629T3/da active
- 1997-03-19 DE DE69716057T patent/DE69716057T2/de not_active Expired - Lifetime
- 1997-03-19 ES ES97915143T patent/ES2185002T3/es not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| CA2249364C (en) | 2009-07-07 |
| DK0896629T3 (da) | 2003-02-03 |
| EP0896629A1 (de) | 1999-02-17 |
| AU2215897A (en) | 1997-10-10 |
| CA2249364A1 (en) | 1997-09-25 |
| WO1997035034A1 (en) | 1997-09-25 |
| DE69716057D1 (de) | 2002-11-07 |
| EP0896629B8 (de) | 2003-01-02 |
| DE69716057T2 (de) | 2003-07-03 |
| ES2185002T3 (es) | 2003-04-16 |
| EP0896629B1 (de) | 2002-10-02 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
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