DK0760010T3 - Fremgangsmåder til screening for Crohn's sygdom under anvendelse af TNF-mikrosatellit-alleler - Google Patents

Fremgangsmåder til screening for Crohn's sygdom under anvendelse af TNF-mikrosatellit-alleler

Info

Publication number
DK0760010T3
DK0760010T3 DK95921264T DK95921264T DK0760010T3 DK 0760010 T3 DK0760010 T3 DK 0760010T3 DK 95921264 T DK95921264 T DK 95921264T DK 95921264 T DK95921264 T DK 95921264T DK 0760010 T3 DK0760010 T3 DK 0760010T3
Authority
DK
Denmark
Prior art keywords
crohn
disease
screening
microsatellite alleles
methods
Prior art date
Application number
DK95921264T
Other languages
English (en)
Inventor
Scott E Plevy
Jerome I Rotter
Stephan R Targan
Hiroo Toyoda
Huiying Yang
Original Assignee
Cedars Sinai Medical Center
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cedars Sinai Medical Center filed Critical Cedars Sinai Medical Center
Application granted granted Critical
Publication of DK0760010T3 publication Critical patent/DK0760010T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/6858—Allele-specific amplification
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/172—Haplotypes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Analytical Chemistry (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
DK95921264T 1994-05-17 1995-05-17 Fremgangsmåder til screening for Crohn's sygdom under anvendelse af TNF-mikrosatellit-alleler DK0760010T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US24529794A 1994-05-17 1994-05-17
PCT/US1995/006107 WO1995031575A1 (en) 1994-05-17 1995-05-17 Methods of screening for crohn's disease using tnf microsatellite alleles

Publications (1)

Publication Number Publication Date
DK0760010T3 true DK0760010T3 (da) 2002-02-25

Family

ID=22926104

Family Applications (1)

Application Number Title Priority Date Filing Date
DK95921264T DK0760010T3 (da) 1994-05-17 1995-05-17 Fremgangsmåder til screening for Crohn's sygdom under anvendelse af TNF-mikrosatellit-alleler

Country Status (9)

Country Link
US (2) US6001569A (da)
EP (1) EP0760010B1 (da)
AT (1) ATE207967T1 (da)
AU (1) AU698604B2 (da)
CA (1) CA2190586A1 (da)
DE (1) DE69523586T2 (da)
DK (1) DK0760010T3 (da)
ES (1) ES2166822T3 (da)
WO (1) WO1995031575A1 (da)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6300060B1 (en) 1995-11-09 2001-10-09 Dana-Farber Cancer Institute, Inc. Method for predicting the risk of prostate cancer morbidity and mortality
AU2725697A (en) * 1996-04-12 1997-11-07 Cedars-Sinai Medical Center Methods of identifying and diagnosing inflammatory bowel disease
WO1997039147A1 (en) * 1996-04-12 1997-10-23 Cedars-Sinai Medical Center Methods of identifying and diagnosing inflammatory bowel disease
US5968741A (en) * 1997-04-11 1999-10-19 Cedars-Sinai Medical Center Methods of diagnosing a medically resistant clinical subtype of ulcerative colitis
US6183951B1 (en) 1997-04-11 2001-02-06 Prometheus Laboratories, Inc. Methods of diagnosing clinical subtypes of crohn's disease with characteristic responsiveness to anti-Th1 cytokine therapy
US20030148288A1 (en) * 2002-02-01 2003-08-07 Yi-Wei Tang Colorimetric genetic test for clinically significant TNF polymorphism and methods of use thereof
US6881983B2 (en) * 2002-02-25 2005-04-19 Kopin Corporation Efficient light emitting diodes and lasers
ES2347239T3 (es) 2002-12-02 2010-10-27 Amgen Fremont Inc. Anticuerpos dirigidos al factor de necrosis tumoral y usos de los mismos.
US20070041905A1 (en) * 2005-08-19 2007-02-22 Hoffman Rebecca S Method of treating depression using a TNF-alpha antibody
US8486640B2 (en) 2007-03-21 2013-07-16 Cedars-Sinai Medical Center Ileal pouch-anal anastomosis (IPAA) factors in the treatment of inflammatory bowel disease
WO2010062960A2 (en) 2008-11-26 2010-06-03 Cedars-Sinai Medical Center METHODS OF DETERMINING RESPONSIVENESS TO ANTI-TNFα THERAPY IN INFLAMMATORY BOWEL DISEASE
US9580752B2 (en) 2008-12-24 2017-02-28 Cedars-Sinai Medical Center Methods of predicting medically refractive ulcerative colitis (MR-UC) requiring colectomy
WO2015067913A1 (en) 2013-11-07 2015-05-14 Diagnodus Limited Biomarkers
GB201223223D0 (en) 2012-12-21 2013-02-06 Norinnova Technology Transfer As Inflammatory bowel disease
CN105246501B (zh) 2013-03-27 2021-01-12 雪松-西奈医学中心 通过抑制tl1a的功能和相关信号传导途径来减轻并逆转纤维化和炎症
EP3022295A4 (en) 2013-07-19 2017-03-01 Cedars-Sinai Medical Center Signature of tl1a (tnfsf15) signaling pathway
EP3430172A4 (en) 2016-03-17 2019-08-21 Cedars-Sinai Medical Center METHOD FOR DIAGNOSIS OF INFLAMMATORY ENDURANCE THROUGH RNASET2
US20190256925A1 (en) * 2018-02-20 2019-08-22 Roche Molecular Systems, Inc. Detection of microsatellite instability
CN112831558B (zh) * 2021-03-10 2022-12-20 北京科力丹迪生物医疗科技有限公司 克罗恩病易感基因的早筛方法及试剂盒

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993007485A1 (en) * 1991-10-10 1993-04-15 The Regents Of The University Of California Rare immunoglobulin framework regions associated with human disease
US5225329A (en) * 1991-10-18 1993-07-06 Yale University Method for early detection of intestinal ischemia

Also Published As

Publication number Publication date
AU2638495A (en) 1995-12-05
WO1995031575A1 (en) 1995-11-23
US6534263B1 (en) 2003-03-18
CA2190586A1 (en) 1995-11-23
EP0760010A1 (en) 1997-03-05
ES2166822T3 (es) 2002-05-01
US6001569A (en) 1999-12-14
EP0760010B1 (en) 2001-10-31
AU698604B2 (en) 1998-11-05
DE69523586D1 (de) 2001-12-06
DE69523586T2 (de) 2002-07-18
ATE207967T1 (de) 2001-11-15

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