DK0760010T3 - Fremgangsmåder til screening for Crohn's sygdom under anvendelse af TNF-mikrosatellit-alleler - Google Patents
Fremgangsmåder til screening for Crohn's sygdom under anvendelse af TNF-mikrosatellit-allelerInfo
- Publication number
- DK0760010T3 DK0760010T3 DK95921264T DK95921264T DK0760010T3 DK 0760010 T3 DK0760010 T3 DK 0760010T3 DK 95921264 T DK95921264 T DK 95921264T DK 95921264 T DK95921264 T DK 95921264T DK 0760010 T3 DK0760010 T3 DK 0760010T3
- Authority
- DK
- Denmark
- Prior art keywords
- crohn
- disease
- screening
- microsatellite alleles
- methods
- Prior art date
Links
- 208000011231 Crohn disease Diseases 0.000 title abstract 7
- 108700028369 Alleles Proteins 0.000 title abstract 5
- 108091092878 Microsatellite Proteins 0.000 title abstract 4
- 238000012216 screening Methods 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 2
- 108020004707 nucleic acids Proteins 0.000 abstract 3
- 150000007523 nucleic acids Chemical class 0.000 abstract 3
- 102000039446 nucleic acids Human genes 0.000 abstract 3
- 102100040247 Tumor necrosis factor Human genes 0.000 abstract 2
- 108060008682 Tumor Necrosis Factor Proteins 0.000 abstract 1
- 102000003390 tumor necrosis factor Human genes 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/6858—Allele-specific amplification
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/156—Polymorphic or mutational markers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/172—Haplotypes
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Analytical Chemistry (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Pathology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US24529794A | 1994-05-17 | 1994-05-17 | |
| PCT/US1995/006107 WO1995031575A1 (en) | 1994-05-17 | 1995-05-17 | Methods of screening for crohn's disease using tnf microsatellite alleles |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0760010T3 true DK0760010T3 (da) | 2002-02-25 |
Family
ID=22926104
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK95921264T DK0760010T3 (da) | 1994-05-17 | 1995-05-17 | Fremgangsmåder til screening for Crohn's sygdom under anvendelse af TNF-mikrosatellit-alleler |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US6001569A (da) |
| EP (1) | EP0760010B1 (da) |
| AT (1) | ATE207967T1 (da) |
| AU (1) | AU698604B2 (da) |
| CA (1) | CA2190586A1 (da) |
| DE (1) | DE69523586T2 (da) |
| DK (1) | DK0760010T3 (da) |
| ES (1) | ES2166822T3 (da) |
| WO (1) | WO1995031575A1 (da) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6300060B1 (en) | 1995-11-09 | 2001-10-09 | Dana-Farber Cancer Institute, Inc. | Method for predicting the risk of prostate cancer morbidity and mortality |
| AU2456197A (en) * | 1996-04-12 | 1997-11-07 | Cedars-Sinai Medical Center | Methods of identifying and diagnosing inflammatory bowel disease |
| WO1997039146A1 (en) * | 1996-04-12 | 1997-10-23 | Cedars-Sinai Medical Center | Methods of identifying and diagnosing inflammatory bowel disease |
| US5968741A (en) * | 1997-04-11 | 1999-10-19 | Cedars-Sinai Medical Center | Methods of diagnosing a medically resistant clinical subtype of ulcerative colitis |
| US6183951B1 (en) | 1997-04-11 | 2001-02-06 | Prometheus Laboratories, Inc. | Methods of diagnosing clinical subtypes of crohn's disease with characteristic responsiveness to anti-Th1 cytokine therapy |
| US20030148288A1 (en) * | 2002-02-01 | 2003-08-07 | Yi-Wei Tang | Colorimetric genetic test for clinically significant TNF polymorphism and methods of use thereof |
| US6881983B2 (en) * | 2002-02-25 | 2005-04-19 | Kopin Corporation | Efficient light emitting diodes and lasers |
| US7285269B2 (en) | 2002-12-02 | 2007-10-23 | Amgen Fremont, Inc. | Antibodies directed to tumor necrosis factor |
| US20070041905A1 (en) * | 2005-08-19 | 2007-02-22 | Hoffman Rebecca S | Method of treating depression using a TNF-alpha antibody |
| US8486640B2 (en) | 2007-03-21 | 2013-07-16 | Cedars-Sinai Medical Center | Ileal pouch-anal anastomosis (IPAA) factors in the treatment of inflammatory bowel disease |
| US20110229471A1 (en) | 2008-11-26 | 2011-09-22 | Cedars-Sinai Medical Center | Methods of determining responsiveness to anti-tnf alpha therapy in inflammatory bowel disease |
| US9580752B2 (en) | 2008-12-24 | 2017-02-28 | Cedars-Sinai Medical Center | Methods of predicting medically refractive ulcerative colitis (MR-UC) requiring colectomy |
| WO2015067913A1 (en) | 2013-11-07 | 2015-05-14 | Diagnodus Limited | Biomarkers |
| GB201223223D0 (en) | 2012-12-21 | 2013-02-06 | Norinnova Technology Transfer As | Inflammatory bowel disease |
| KR20240122922A (ko) | 2013-03-27 | 2024-08-13 | 세다르스-신나이 메디칼 센터 | Tl1a 기능 및 관련된 신호전달 경로의 저해에 의한 섬유증 및 염증의 완화 및 반전 |
| EP4105236A1 (en) | 2013-07-19 | 2022-12-21 | Cedars-Sinai Medical Center | Anti-tl1a (tnfsf15) antibody for treatment of inflammatory bowel disease |
| CN109462996A (zh) | 2016-03-17 | 2019-03-12 | 西达-赛奈医疗中心 | 通过rnaset2诊断炎性肠病的方法 |
| CN111670254B (zh) * | 2018-02-20 | 2024-10-11 | 豪夫迈·罗氏有限公司 | 微卫星不稳定性的改进检测 |
| CN112831558B (zh) * | 2021-03-10 | 2022-12-20 | 北京科力丹迪生物医疗科技有限公司 | 克罗恩病易感基因的早筛方法及试剂盒 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1993007485A1 (en) * | 1991-10-10 | 1993-04-15 | The Regents Of The University Of California | Rare immunoglobulin framework regions associated with human disease |
| US5225329A (en) * | 1991-10-18 | 1993-07-06 | Yale University | Method for early detection of intestinal ischemia |
-
1995
- 1995-05-17 ES ES95921264T patent/ES2166822T3/es not_active Expired - Lifetime
- 1995-05-17 AT AT95921264T patent/ATE207967T1/de not_active IP Right Cessation
- 1995-05-17 CA CA002190586A patent/CA2190586A1/en not_active Abandoned
- 1995-05-17 DE DE69523586T patent/DE69523586T2/de not_active Expired - Fee Related
- 1995-05-17 AU AU26384/95A patent/AU698604B2/en not_active Ceased
- 1995-05-17 WO PCT/US1995/006107 patent/WO1995031575A1/en not_active Ceased
- 1995-05-17 EP EP95921264A patent/EP0760010B1/en not_active Expired - Lifetime
- 1995-05-17 DK DK95921264T patent/DK0760010T3/da active
-
1997
- 1997-02-11 US US08/798,668 patent/US6001569A/en not_active Expired - Lifetime
-
1999
- 1999-10-15 US US09/419,406 patent/US6534263B1/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| US6534263B1 (en) | 2003-03-18 |
| EP0760010B1 (en) | 2001-10-31 |
| US6001569A (en) | 1999-12-14 |
| ES2166822T3 (es) | 2002-05-01 |
| WO1995031575A1 (en) | 1995-11-23 |
| CA2190586A1 (en) | 1995-11-23 |
| EP0760010A1 (en) | 1997-03-05 |
| AU2638495A (en) | 1995-12-05 |
| DE69523586T2 (de) | 2002-07-18 |
| ATE207967T1 (de) | 2001-11-15 |
| AU698604B2 (en) | 1998-11-05 |
| DE69523586D1 (de) | 2001-12-06 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DK0760010T3 (da) | Fremgangsmåder til screening for Crohn's sygdom under anvendelse af TNF-mikrosatellit-alleler | |
| NO975508D0 (no) | DNA-sekvens og kodet bryst- spesifikk brystkreftprotein | |
| ATE408422T1 (de) | Methode zur hemmung immunstimulatorischer mit dna assoziierter antworten | |
| NO941887L (no) | Metallocener med silylbroer og deres anvendelse | |
| DE69216478D1 (de) | Sequenz-spezifische DNS-Bindung durch P53 | |
| DE69941701D1 (de) | Mutanten von flt3-l und ihre verwendungen | |
| WO2000037679A3 (en) | Method for determining the susceptibility to developing sepsis and therapeutics for the treatment of sepsis | |
| IT1267464B1 (it) | Procedimento per la produzione di carburo di ferro. | |
| EA200200565A1 (ru) | Применение клеток, трансфицированных днк, кодирующей лиганд мнс класса ii, и способ получения таких клеток | |
| FI946127A7 (fi) | Menetelmä alukkeen pidentämiseksi yhdellä nukleotidilla spesifisten al leelien detektoimiseksi, ja testipakkaus näiden menetelmien suorittami seksi | |
| DE3682149D1 (de) | Verfahren zur quantitativen bestimmung von 1,5-anhydroglucitol. | |
| ES2175095T3 (es) | Marcadores de adn respecto al tamaño de una camada de cerdos. | |
| CA2269664A1 (en) | Diagnostic assay for breast cancer susceptibility | |
| MX9702789A (es) | Novedosas proteinas ligandos del dominio de la muerte del receptor tnf, e inhibidores de la union delos ligandos. | |
| EP0547920A3 (en) | Recombinant thermostable dna polymerase from archaebacteria | |
| AU2174392A (en) | Adn sequences of the human papillomavirus type 42, and diagnostic application thereof | |
| ATE305037T1 (de) | Peptide, die fähig sind die sh3-domäne des gap- proteins zu binden, ihre kodierende dns, ihre zubereitung und verwendung | |
| SE9602822D0 (sv) | New receptor | |
| NO995438D0 (no) | Fremgangsmåter for å screene forbindelser nyttige for forhindring av infeksjon eller patogenisitet | |
| DE59005312D1 (de) | Verwendung der Feinfraktion von Gewässersedimenten. | |
| WO1998024896A3 (en) | Muteins of obese protein | |
| EP1108212A4 (en) | METHODS AND MATERIALS FOR DIAGNOSING AN UNSTABLE ANGOR | |
| DE59914061D1 (de) | Das gen prv-1 und dessen verwendung | |
| CA2308766A1 (en) | Diagnostic assay for cancer susceptibility | |
| EP0850249A4 (en) | Novel detection methods for cryptosporidium |