HK1069121A1 - Agent for prophylaxis and treatment of asthenopia and pseudomyopia - Google Patents
Agent for prophylaxis and treatment of asthenopia and pseudomyopiaInfo
- Publication number
- HK1069121A1 HK1069121A1 HK05102431.8A HK05102431A HK1069121A1 HK 1069121 A1 HK1069121 A1 HK 1069121A1 HK 05102431 A HK05102431 A HK 05102431A HK 1069121 A1 HK1069121 A1 HK 1069121A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- prophylaxis
- treatment
- agent
- glaucoma
- compound
- Prior art date
Links
- 238000011321 prophylaxis Methods 0.000 title abstract 5
- 238000011282 treatment Methods 0.000 title abstract 5
- 208000003464 asthenopia Diseases 0.000 title 1
- 230000004436 pseudomyopia Effects 0.000 title 1
- 208000010412 Glaucoma Diseases 0.000 abstract 4
- 150000001875 compounds Chemical class 0.000 abstract 3
- 230000002401 inhibitory effect Effects 0.000 abstract 2
- 102000000568 rho-Associated Kinases Human genes 0.000 abstract 2
- 108010041788 rho-Associated Kinases Proteins 0.000 abstract 2
- 210000001742 aqueous humor Anatomy 0.000 abstract 1
- 230000017531 blood circulation Effects 0.000 abstract 1
- 230000004410 intraocular pressure Effects 0.000 abstract 1
- 230000001737 promoting effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4409—Non condensed pyridines; Hydrogenated derivatives thereof only substituted in position 4, e.g. isoniazid, iproniazid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/4545—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. pipamperone, anabasine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/10—Ophthalmic agents for accommodation disorders, e.g. myopia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Ophthalmology & Optometry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pyridine Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicinal Preparation (AREA)
- Pyrane Compounds (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP24776298 | 1998-08-17 | ||
JP12296099 | 1999-04-28 | ||
HK01101779A HK1030883A1 (en) | 1998-08-17 | 2001-03-12 | Preventives/remedies for glaucoma |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1069121A1 true HK1069121A1 (en) | 2005-05-13 |
Family
ID=26459997
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK05102430.9A HK1069120A1 (en) | 1998-08-17 | 2001-03-12 | Agent for prophylaxis and treatment of glaucoma |
HK05102431.8A HK1069121A1 (en) | 1998-08-17 | 2001-03-12 | Agent for prophylaxis and treatment of asthenopia and pseudomyopia |
HK01101779A HK1030883A1 (en) | 1998-08-17 | 2001-03-12 | Preventives/remedies for glaucoma |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK05102430.9A HK1069120A1 (en) | 1998-08-17 | 2001-03-12 | Agent for prophylaxis and treatment of glaucoma |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK01101779A HK1030883A1 (en) | 1998-08-17 | 2001-03-12 | Preventives/remedies for glaucoma |
Country Status (12)
Country | Link |
---|---|
US (2) | US6673812B1 (fr) |
EP (3) | EP1459743B9 (fr) |
JP (2) | JP3720264B2 (fr) |
KR (1) | KR100616466B1 (fr) |
CN (2) | CN1195547C (fr) |
AT (3) | ATE307609T1 (fr) |
AU (1) | AU5198199A (fr) |
CA (2) | CA2307285C (fr) |
DE (1) | DE69927936T2 (fr) |
ES (3) | ES2247822T3 (fr) |
HK (3) | HK1069120A1 (fr) |
WO (1) | WO2000009162A1 (fr) |
Families Citing this family (82)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN100444843C (zh) * | 1998-08-10 | 2008-12-24 | 旭化成制药株式会社 | 法舒地尔盐酸盐缓释口服制剂 |
AU3328600A (en) * | 1999-03-25 | 2000-10-16 | Santen Pharmaceutical Co. Ltd. | Ocular tension-lowering agents |
DE60036540T2 (de) * | 1999-03-25 | 2008-07-03 | Mitsubishi Tanabe Pharma Corp. | Rho-kinase-inhibitoren für die vorbeugung oder behandlung von interstitieller pneumonie und pulmonaler fibrose |
US9603741B2 (en) | 2000-05-19 | 2017-03-28 | Michael S. Berlin | Delivery system and method of use for the eye |
CA2422488A1 (fr) | 2000-09-20 | 2002-03-28 | Merck Patent Gesellschaft Mit Beschraenkter Haftung | 4-amino-quinazolines |
WO2002083175A1 (fr) | 2001-04-11 | 2002-10-24 | Senju Pharmaceutical Co., Ltd. | Agents ameliorant la fonction visuelle |
JP2003010158A (ja) * | 2001-04-26 | 2003-01-14 | Biochemical & Pharmacological Laboratories Inc | 眼精疲労モデル、その作製方法、そのモデルを用いた評価方法およびその評価法を用いて選択された薬剤 |
US7829566B2 (en) | 2001-09-17 | 2010-11-09 | Werner Mederski | 4-amino-quinazolines |
ES2305435T3 (es) | 2002-01-10 | 2008-11-01 | Bayer Healthcare Ag | Inhibidores de la rho-quinasa. |
CA2473910C (fr) | 2002-01-23 | 2011-03-15 | Bayer Pharmaceuticals Corporation | Derives de pyrimidine en tant qu'inhibiteurs de la rho-kinase |
MXPA04007191A (es) | 2002-01-23 | 2005-03-31 | Bayer Pharmaceuticals Corp | Derivados de pirimidina como inhibidores de rho-quinasa. |
US7645878B2 (en) | 2002-03-22 | 2010-01-12 | Bayer Healthcare Llc | Process for preparing quinazoline Rho-kinase inhibitors and intermediates thereof |
GB0206860D0 (en) | 2002-03-22 | 2002-05-01 | Glaxo Group Ltd | Compounds |
TWI337881B (en) * | 2002-08-29 | 2011-03-01 | Santen Pharmaceutical Co Ltd | Treating agent for glaucoma comprising rho kinase inhibitor and prostaglandin |
AU2003269413A1 (en) * | 2002-11-01 | 2004-05-25 | Pharmacia & Upjohn Company Llc | Nicotinic acetylcholine agonists in the treatment of glaucoma and retinal neuropathy |
AU2003280812A1 (en) * | 2002-11-18 | 2004-06-15 | Santen Pharmaceutical Co., Ltd. | REMEDY FOR GLAUCOMA COMPRISING Rho KINASE INHIBITOR AND Beta-BLOCKER |
US7160894B2 (en) * | 2003-06-06 | 2007-01-09 | Asahi Kasei Pharma Corporation | Tricyclic compound |
CN100390173C (zh) * | 2003-06-06 | 2008-05-28 | 旭化成制药株式会社 | 3环系化合物 |
KR101163800B1 (ko) | 2003-10-15 | 2012-07-09 | 산텐 세이야꾸 가부시키가이샤 | 신규 인다졸 유도체 |
US8415364B2 (en) | 2003-11-26 | 2013-04-09 | Duke University | Method of preventing or treating glaucoma |
US7083783B2 (en) * | 2004-02-18 | 2006-08-01 | Wisconsin Alumni Research Foundation | Method for treating glaucoma |
WO2005102345A1 (fr) * | 2004-03-30 | 2005-11-03 | Alcon, Inc. | Utilisation d'inhibiteurs de kinase rho dans le traitement de deficits auditifs, d'acouphenes et dans l'amelioration de l'equilibre corporel |
FR2868310A1 (fr) * | 2004-04-02 | 2005-10-07 | Oreal | Utilisation cosmetique d'au moins un inhibiteur de la production et/ou de l'activation des rhoa kinases comme agent destine a detendre les traits et/ou decontracter la peau |
JP4932480B2 (ja) * | 2004-06-03 | 2012-05-16 | 千寿製薬株式会社 | アミド化合物を含有する角膜知覚回復剤 |
TWI367098B (en) | 2004-12-23 | 2012-07-01 | Kowa Co | Treating agent for glaucoma |
ATE519488T1 (de) * | 2004-12-27 | 2011-08-15 | Novartis Ag | Aminopyrazin-analoga zur behandlung von glaukomen und anderen durch rho-kinase verursachten krankheiten |
WO2006088088A1 (fr) * | 2005-02-16 | 2006-08-24 | Astellas Pharma Inc. | Remède contre la douleur contenant un inhibiteur de la protéine rho-kinase |
KR101326425B1 (ko) * | 2005-06-21 | 2013-11-11 | 코와 가부시키가이샤 | 녹내장의 예방 또는 치료제 |
KR101333990B1 (ko) | 2005-07-12 | 2013-11-27 | 코와 가부시키가이샤 | 녹내장을 예방 또는 치료하는 약제 |
EP1922306A2 (fr) | 2005-09-02 | 2008-05-21 | Astellas Pharma Inc. | Dérivés d'amides comme inhibiteurs rock |
US7867999B1 (en) | 2005-12-22 | 2011-01-11 | Alcon Research, Ltd. | Hydroxyamino- and amino-substituted pyridine analogs for treating rho kinase-mediated diseases and conditions |
EP1962853A1 (fr) | 2005-12-22 | 2008-09-03 | Alcon Research, Ltd. | (indazol-5-yl)-pyrazines et (1,3-dihydro-indol-2-un)- pyrazines pour le traitement de maladies et de conditions a mediation de rho kinase |
CA2653424A1 (fr) | 2006-06-08 | 2007-12-13 | Ube Industries, Ltd. | Nouveau derive d'indazole ayant une structure cyclique spiro dans une chaine laterale |
EP2050449A4 (fr) * | 2006-07-31 | 2010-10-06 | Senju Pharma Co | Préparation liquide aqueuse contenant un amide |
US20100022517A1 (en) * | 2006-12-18 | 2010-01-28 | Richards Lori A | Ophthalmic formulation of rho kinase inhibitor compound |
AR064420A1 (es) * | 2006-12-21 | 2009-04-01 | Alcon Mfg Ltd | Composiciones farmaceuticas oftalmicas que comprenden una cantidad efectiva de analogos de 6-aminoimidazo[1,2b]piridazinas, utiles para el tratamiento del glaucoma y/o controlar la presion intraocular normal o elevada(iop). |
ES2375522T3 (es) | 2006-12-26 | 2012-03-01 | Santen Pharmaceutical Co., Ltd | Nuevo derivado de n-(2-aminofenil)benzamida con estructura urea. |
WO2008117862A1 (fr) | 2007-03-28 | 2008-10-02 | Santen Pharmaceutical Co., Ltd. | Nouveau dérivé de (2-aminophényl)pyridinecarboxamide ayant une structure d'urée |
WO2008123395A1 (fr) | 2007-03-28 | 2008-10-16 | Santen Pharmaceutical Co., Ltd. | Agent hypotenseur oculaire comprenant un composé capable d'inhiber une histone désacétylase comme principe actif |
CN101808994B (zh) | 2007-07-17 | 2013-05-15 | 普莱希科公司 | 用于激酶调节的化合物和方法以及其适应症 |
KR20150088907A (ko) | 2007-08-29 | 2015-08-03 | 센주 세이야꾸 가부시키가이샤 | 각막 내피 세포 접착 촉진제 |
KR101467841B1 (ko) * | 2007-09-21 | 2015-01-29 | 아이진 주식회사 | 트롬빈 유래 펩타이드를 포함하는 망막증 또는 녹내장 치료용 조성물 |
US20170360609A9 (en) | 2007-09-24 | 2017-12-21 | Ivantis, Inc. | Methods and devices for increasing aqueous humor outflow |
JP2011513002A (ja) | 2008-03-05 | 2011-04-28 | イバンティス インコーポレイテッド | 緑内障を治療する方法及び器具 |
EP2292611B1 (fr) | 2008-05-23 | 2012-07-25 | Santen Pharmaceutical Co., Ltd | Nouveau dérivé de thiophènediamine ayant une structure d urée |
EP2319539A4 (fr) * | 2008-07-24 | 2012-03-28 | Univ Osaka | Agent prophylactique ou thérapeutique pour la myopie axiale |
JPWO2010010715A1 (ja) * | 2008-07-25 | 2012-01-05 | 旭化成ファーマ株式会社 | スルホンアミド化合物を含有する安定な水溶液組成物 |
US8273900B2 (en) | 2008-08-07 | 2012-09-25 | Novartis Ag | Organic compounds |
EP2331507A2 (fr) * | 2008-09-18 | 2011-06-15 | Astellas Pharma Inc. | Composés de carboxamide hétérocycliques |
US10272035B2 (en) * | 2008-11-13 | 2019-04-30 | Gholam A. Peyman | Ophthalmic drug delivery method |
US10842669B2 (en) | 2008-11-13 | 2020-11-24 | Gholam A. Peyman | Ophthalmic drug delivery method |
US20110125090A1 (en) * | 2008-11-13 | 2011-05-26 | Peyman Gholam A | Ophthalmic drug delivery system and method |
US9447089B2 (en) | 2009-04-03 | 2016-09-20 | Plexxikon Inc. | Compositions and uses thereof |
US8299079B2 (en) | 2009-05-22 | 2012-10-30 | Kaufman Herbert E | Preparations and methods for ameliorating or reducing presbyopia |
WO2010135731A1 (fr) * | 2009-05-22 | 2010-11-25 | Kaufman Herbert E | Préparations et procédés pour améliorer ou réduire une presbytie |
CA2766192C (fr) | 2009-07-09 | 2017-10-24 | Ivantis, Inc. | Implants oculaires destines a une installation partielle dans le canal de schlemm |
CN102481171B (zh) | 2009-07-09 | 2015-01-28 | 伊万提斯公司 | 用于输送眼部植入物的单人操作装置 |
US8329724B2 (en) | 2009-08-03 | 2012-12-11 | Hoffmann-La Roche Inc. | Process for the manufacture of pharmaceutically active compounds |
WO2011021221A2 (fr) | 2009-08-17 | 2011-02-24 | Reliance Life Sciences Pvt. Ltd. | Compositions destinées aux lésions de la moelle épinière |
UA105813C2 (uk) | 2009-11-06 | 2014-06-25 | Плексікон, Інк. | Сполуки-інгібітори кіназ та фармацевтична композиція (варіанти) |
CA2803689A1 (fr) * | 2010-07-27 | 2012-02-02 | Inspire Pharmaceuticals, Inc. | Methode de traitement de maladies ophtalmiques a l'aide de composes d'inhibiteurs de kinase sous forme de promedicaments |
US20130310370A1 (en) | 2011-02-04 | 2013-11-21 | Kowa Co., Ltd. | Drug therapy for preventing or treating glaucoma |
AU2012214762B2 (en) | 2011-02-07 | 2015-08-13 | Plexxikon Inc. | Compounds and methods for kinase modulation, and indications therefor |
TWI558702B (zh) | 2011-02-21 | 2016-11-21 | 普雷辛肯公司 | 醫藥活性物質的固態形式 |
US8657776B2 (en) | 2011-06-14 | 2014-02-25 | Ivantis, Inc. | Ocular implants for delivery into the eye |
US8663150B2 (en) | 2011-12-19 | 2014-03-04 | Ivantis, Inc. | Delivering ocular implants into the eye |
US9358156B2 (en) | 2012-04-18 | 2016-06-07 | Invantis, Inc. | Ocular implants for delivery into an anterior chamber of the eye |
US9150570B2 (en) | 2012-05-31 | 2015-10-06 | Plexxikon Inc. | Synthesis of heterocyclic compounds |
CA2878370C (fr) * | 2012-07-13 | 2021-01-19 | Santen Pharmaceutical Co., Ltd. | Combinaison de composes de sulfonamide aux fins de traitement d'un glaucome ou d'une hypertension oculaire |
US10617558B2 (en) | 2012-11-28 | 2020-04-14 | Ivantis, Inc. | Apparatus for delivering ocular implants into an anterior chamber of the eye |
CN105050600B (zh) | 2013-04-24 | 2018-09-28 | 国立大学法人九州大学 | 眼底疾病治疗剂 |
WO2016011056A1 (fr) | 2014-07-14 | 2016-01-21 | Ivantis, Inc. | Système et procédé de pose d'implant oculaire |
US9844556B2 (en) | 2015-03-25 | 2017-12-19 | Megumi Honjo | Preventive/therapeutic method and preventive/therapeutic agent for complications after cataract surgery |
AU2016307951B2 (en) | 2015-08-14 | 2021-04-01 | Alcon Inc. | Ocular implant with pressure sensor and delivery system |
EP4088719A1 (fr) | 2015-10-13 | 2022-11-16 | Institut National de la Santé et de la Recherche Médicale (INSERM) | Procédés et compositions pharmaceutiques pour le traitement de non-perfusion capillaire rétinienne |
US12048761B2 (en) | 2015-10-13 | 2024-07-30 | Inserm (Institut National De La Santé Et De La Recherche Medicale) | Methods and pharmaceutical compositions for the treatment of retinal capillary non-perfusion |
WO2017106517A1 (fr) * | 2015-12-15 | 2017-06-22 | Ivantis, Inc. | Implant vasculaire et système de pose |
TWI833535B (zh) | 2017-12-21 | 2024-02-21 | 日商參天製藥股份有限公司 | 賽佩普斯特(Sepetaprost)及Rho激酶抑制劑之組合醫藥 |
AU2019223946B2 (en) | 2018-02-22 | 2021-05-20 | Alcon Inc. | Ocular implant and delivery system |
CA3166602A1 (fr) | 2020-02-05 | 2021-08-12 | Nicoletta Almirante | Compositions pour le traitement du glaucome et de l'hypertension oculaire |
WO2022150676A1 (fr) | 2021-01-11 | 2022-07-14 | Incyte Corporation | Polythérapie comprenant un inhibiteur de la voie jak et un inhibiteur de rock |
JP2024503989A (ja) | 2021-01-11 | 2024-01-30 | アルコン インコーポレイティド | 粘弾性体送達のためのシステム及び方法 |
Family Cites Families (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4838677A (en) | 1987-04-06 | 1989-06-13 | Ayetech Inc. | Eye exercising devices |
US5250547A (en) | 1991-08-29 | 1993-10-05 | Syntex (U.S.A.) Inc. | Benzopyran derivatives |
KR0133372B1 (ko) | 1991-09-06 | 1998-04-23 | 고야 다다시 | 4-아미노(알킬)시클로헥산-1-카르복사미드 화합물 및 그 용도 |
IL104755A0 (en) | 1992-02-17 | 1993-06-10 | Ciba Geigy Ag | Treatment of glaucoma |
IL103932A (en) | 1992-11-30 | 1997-02-18 | Yissum Res & Dev | Fatty acid and pharmaceutical compositions containing them |
US5618955A (en) | 1992-11-30 | 1997-04-08 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Fatty acid derivatives and pharmaceutical compositions containing same |
JP3066561B2 (ja) * | 1993-10-07 | 2000-07-17 | 武田薬品工業株式会社 | 近視予防・治療剤 |
JPH07133225A (ja) | 1993-11-09 | 1995-05-23 | Santen Pharmaceut Co Ltd | 毛様体筋緊張緩和剤 |
EP1195372A1 (fr) * | 1994-04-18 | 2002-04-10 | Mitsubishi Pharma Corporation | Dérivés benzamide substitués avec un N-hétérocycle présentant des propriétés antihypertensives |
JPH08198876A (ja) | 1995-01-30 | 1996-08-06 | Yoshitomi Pharmaceut Ind Ltd | トランス−N−(1H−ピラゾロ〔3,4−b〕ピリジン−4−イル)−4−グアニジノメチルシクロヘキサンカルボキサミド・1メタンスルホン酸塩・1水和物 |
US5888173A (en) | 1995-08-10 | 1999-03-30 | Singhal; Tara Chand | Health saver computer break |
JP3421217B2 (ja) * | 1995-11-20 | 2003-06-30 | 麒麟麦酒株式会社 | Rho標的タンパク質Rhoキナーゼ |
US5906819A (en) | 1995-11-20 | 1999-05-25 | Kirin Beer Kabushiki Kaisha | Rho target protein Rho-kinase |
JPH09143099A (ja) | 1995-11-27 | 1997-06-03 | Santen Pharmaceut Co Ltd | 毛様体筋緊張緩和剤 |
KR100452715B1 (ko) | 1995-12-21 | 2004-12-17 | 알콘 래보레이토리스, 인코퍼레이티드 | 녹내장및안구국소빈혈을치료하기위한특정이소퀴놀린술포닐화합물의용도 |
US5798380A (en) | 1996-02-21 | 1998-08-25 | Wisconsin Alumni Research Foundation | Cytoskeletal active agents for glaucoma therapy |
JPH10203982A (ja) * | 1996-07-05 | 1998-08-04 | Takeda Chem Ind Ltd | 視機能障害の予防・治療剤 |
ATE359822T1 (de) * | 1996-08-12 | 2007-05-15 | Mitsubishi Pharma Corp | Medikamente enthaltend rho-kinase inhibitoren |
-
1999
- 1999-08-13 ES ES99937073T patent/ES2247822T3/es not_active Expired - Lifetime
- 1999-08-13 CN CNB998018732A patent/CN1195547C/zh not_active Expired - Fee Related
- 1999-08-13 AT AT99937073T patent/ATE307609T1/de not_active IP Right Cessation
- 1999-08-13 JP JP2000564663A patent/JP3720264B2/ja not_active Expired - Fee Related
- 1999-08-13 WO PCT/JP1999/004403 patent/WO2000009162A1/fr active IP Right Grant
- 1999-08-13 ES ES04014077T patent/ES2374518T3/es not_active Expired - Lifetime
- 1999-08-13 EP EP04014078A patent/EP1459743B9/fr not_active Expired - Lifetime
- 1999-08-13 CN CNB2003101142105A patent/CN1293878C/zh not_active Expired - Fee Related
- 1999-08-13 AT AT04014077T patent/ATE527993T1/de not_active IP Right Cessation
- 1999-08-13 EP EP99937073A patent/EP1034793B1/fr not_active Expired - Lifetime
- 1999-08-13 AT AT04014078T patent/ATE529102T1/de not_active IP Right Cessation
- 1999-08-13 ES ES04014078T patent/ES2372572T3/es not_active Expired - Lifetime
- 1999-08-13 CA CA002307285A patent/CA2307285C/fr not_active Expired - Fee Related
- 1999-08-13 AU AU51981/99A patent/AU5198199A/en not_active Abandoned
- 1999-08-13 CA CA2635412A patent/CA2635412C/fr not_active Expired - Fee Related
- 1999-08-13 EP EP04014077A patent/EP1459742B9/fr not_active Expired - Lifetime
- 1999-08-13 DE DE69927936T patent/DE69927936T2/de not_active Expired - Lifetime
- 1999-08-13 KR KR1020007004051A patent/KR100616466B1/ko not_active IP Right Cessation
- 1999-08-13 US US09/529,354 patent/US6673812B1/en not_active Expired - Lifetime
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2001
- 2001-03-12 HK HK05102430.9A patent/HK1069120A1/xx not_active IP Right Cessation
- 2001-03-12 HK HK05102431.8A patent/HK1069121A1/xx not_active IP Right Cessation
- 2001-03-12 HK HK01101779A patent/HK1030883A1/xx not_active IP Right Cessation
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2002
- 2002-11-19 US US10/298,674 patent/US6649625B2/en not_active Expired - Fee Related
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2004
- 2004-07-06 JP JP2004199836A patent/JP4490748B2/ja not_active Expired - Fee Related
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PC | Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee) |
Effective date: 20150813 |